摘要:
This invention is directed toward monoclonal antibodies that bind specifically to Notch1. In one embodiment, the antibodies binds to at least a first epitope and a second epitope, wherein the first epitope resides with the LinA domain of the Notch1 negative regulatory region (NRR), and the second epitope resides within the HD-C domain of the Notch1 NRR.
摘要:
A system and methods for the efficient segmentation of globally optimal surfaces representing object boundaries in volumetric datasets is provided. An optical surface detection system and methods are provided that are capable of simultaneously detecting multiple interacting surfaces in which the optimality is controlled by the cost functions designed for individual surfaces and by several geometric constraints defining the surface smoothness and interrelations.
摘要:
The present invention relates to agonist antibodies that specifically bind to Notch 3 and activate signaling. The present invention includes antibodies binding to an epitope comprising the first Lin12 domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
摘要:
A method for controlling a lamp circuit that includes: setting a first voltage threshold and a first time window within a control circuit corresponding to a characteristic of a first lamp type; providing a first signal through the lamp circuit to start a first time interval and create a first test voltage; comparing the first test voltage to the first voltage threshold; and operating a switch to couple an output of the lamp circuit to a source of electrical power if the first test voltage is greater than or equal to the first voltage threshold before the first time interval exceeds the first time window.
摘要:
A method of recovering hydrocarbons from a porous subterranean hydrocarbon-bearing formation by: (a) reducing the salinity of a saline source water by reverse osmosis using a membrane having a first surface and a second surface by (i) feeding the saline source water to the first surface of the membrane, and (ii) removing treated water of reduced salinity from the second surface of the membrane; and (b) injecting the treated water into the formation; wherein the membrane is selectively permeable to water over dissolved solids such that when (i) the saline source water has a total dissolved solids content of at least 17,500 ppm, and (ii) the applied pressure across the membrane is greater than the osmotic pressure across the membrane and lies within the range 45 to 90 bar (4.5 to 9.0 MPa), the total dissolved solids content of the treated water is in the range 500 to 5000 ppm. Increased oil recovery can be achieved.
摘要:
The present invention relates to agonist antibodies that specifically bind to Notch 3 and activate signaling. The present invention includes antibodies binding to an epitope comprising the first Lin12 domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
摘要:
A system and methods for the efficient segmentation of globally optimal surfaces representing object boundaries in volumetric datasets is provided. An optical surface detection system and methods are provided that are capable of simultaneously detecting multiple interacting surfaces in which the optimality is controlled by the cost functions designed for individual surfaces and by several geometric constraints defining the surface smoothness and interrelations.
摘要:
An electrical circuit whose slow rate can be changed. Included in the circuit is an input node for applying a voltage signal, a first switch in series with the input node, and a resistance in series with and in-between the input node and first switch. The slew rate of the circuit is adjusted by changing the equivalent resistance between the input node and the first switch based upon a control signal.
摘要:
A PWM current control circuit that determines whether a start-up time, during which an decreased current is being drawn, for a load has elapsed and providing a switch that supplies current to the load with a control signal that limits the current being drawn if the start-up time has not elapsed and providing a standard PWM control signal from a microcontroller if the start-up time has not elapsed. Excessive inrush current during the start-up period of the load is avoided while the current is maintained to be within a predetermined range during start-up and after the start-up time has elapsed the control is again turned over to the microcontroller.
摘要:
A system and method for detecting the presence of a voltage on a ground conductor which is coupled to a protective Earth (PE) terminal associated with a power source. The power source is used to apply a voltage to a device. The system may use a high impedance device coupled across a switch, with the switch being in communication with a portion of the device. A control system may monitor a voltage across the high impedance device and determine if the voltage across the high impedance device exceeds a predetermined threshold. Exceeding the predetermined threshold indicates that an unsafe voltage from the power source is present on the ground conductor. A natural high impedance path between the device and the Earth is used to provide an Earth connection through the device to the Earth during operation of the system.