公开(公告)号：US5160672A

公开(公告)日：1992-11-03

申请号：US358618

申请日：1989-05-30

申请人： Masatomi Sasaki ,  Nobuyoshi Kashiwagi ,  Hiroki Sakakibara ,  Makoto Saruhashi

发明人： Masatomi Sasaki ,  Nobuyoshi Kashiwagi ,  Hiroki Sakakibara ,  Makoto Saruhashi

IPC分类号： B01D67/00 ,  A61M1/18 ,  B01D69/08 ,  B01D71/10 ,  D01D5/24 ,  D01F2/04 ,  D01F6/00

CPC分类号： D01D5/24 ,  B01D69/08

摘要： A method for the production of a hollow fiber membrane by the steps of discharging a spinning dope through an annular spinning nozzle and, at the same time, introducing a non-coagulating liquid for the spinning dope into the central cavity in a hollow fiber of the spinning dope being discharged, and then introducing the discharged fiber of the spinning dope into a coagulating liquid thereby solidifying the discharged fiber into a hollow fiber membrane, which method is characterized by incorporating a surface modifying agent in said non-coagulating liquid thereby modifying the inner surface behavior of the produced hollow fiber membrane.

公开(公告)号：US5489303A

公开(公告)日：1996-02-06

申请号：US200569

申请日：1994-02-22

申请人： Masatomi Sasaki ,  Hiroki Sakakibara ,  Makoto Saruhashi ,  Shinichi Tategami

发明人： Masatomi Sasaki ,  Hiroki Sakakibara ,  Makoto Saruhashi ,  Shinichi Tategami

IPC分类号： A61L33/00 ,  B01D67/00 ,  C08G65/332 ,  A61F2/02 ,  A61F2/06

CPC分类号： B01D67/0093 ,  A61L33/0005 ,  A61L33/0082 ,  C08G65/3322 ,  B01D2323/38

摘要： A medical material which comprises an oil-soluble vitamin hydrophobically bound to a hydrophobic moiety containing macromer which is bound to the surface of a polymeric substrate via a copolymer is described. Suitable macromers include for example glycidyl methacrylate-linoleic acid. Suitable polymeric substrate materials include, in particular, cellulose. Methods for producing said medical material are also provided.

摘要翻译： 描述了包含与通过共聚物结合到聚合物基材的表面的含疏水部分的大分子单体疏水结合的油溶性维生素的医疗材料。 合适的大分子单体包括例如甲基丙烯酸缩水甘油酯 - 亚油酸。 合适的聚合物基材包括，特别是纤维素。 还提供了生产所述医疗材料的方法。

公开(公告)号：US20090014366A1

公开(公告)日：2009-01-15

申请号：US12278585

申请日：2007-02-14

申请人： Hatsumi Takeda ,  Atsushi Hatakeyama ,  Futomitsu Horiuchi ,  Hiroki Sakakibara

发明人： Hatsumi Takeda ,  Atsushi Hatakeyama ,  Futomitsu Horiuchi ,  Hiroki Sakakibara

IPC分类号： B01D35/14 ,  C02F1/00 ,  C02F103/04

CPC分类号： B01D63/024 ,  B01D61/18 ,  B01D2311/2626 ,  B01D2313/40 ,  C02F1/001 ,  C02F1/281 ,  C02F1/283 ,  C02F1/32 ,  C02F1/42 ,  C02F1/444 ,  C02F1/78 ,  C02F9/005

摘要： A drinking water device including a water storage section that stores drinking water inside an installation type casing; a water outlet that is connected to the water storage section via a passage and is located outside the casing; filtering device that is provided in the passage on further upstream side of the water outlet so as to be freely attachable/detachable; and a flow rate switch, which is provided between the water storage section and the water outlet and which is capable of detecting flow rate of the drinking water and also capable of outputting an actuating signal upon detecting the flow rate within a preset flow rate range.

摘要翻译： 一种饮用水装置，包括：储水部，其将饮用水储存在安装型壳体的内部; 出水口，经由通道连接到储水部并且位于壳体外部; 过滤装置，其设置在所述通道的另一上游侧，以便可自由地安装/拆卸; 以及流量开关，其设置在储水部和出水口之间，并且能够检测饮用水的流量，并且还能够在预设流量范围内检测流量时输出致动信号。

公开(公告)号：US5679372A

公开(公告)日：1997-10-21

申请号：US424414

申请日：1995-04-26

申请人： Yasuhiko Shimuzu ,  Toru Natsume ,  Toshikazu Makihara ,  Masanori Akasaka ,  Hiroki Sakakibara

发明人： Yasuhiko Shimuzu ,  Toru Natsume ,  Toshikazu Makihara ,  Masanori Akasaka ,  Hiroki Sakakibara

IPC分类号： A61L15/32 ,  A61L15/00 ,  A61F13/00 ,  A61M35/00

CPC分类号： A61L15/325 ,  A61L2400/04

摘要： An absorbable spun, cotton-like topical hemostat containing fibers entangled with each other and being made of atelcollagen obtained by reconstituting solubilized collagen. Each of the fibers has a diameter of 10 to 70 .mu.m and a length of 3 to 70 mn. At least a part of the collagen molecules constituting the fibers are crosslinked by heat at a temperature of 50.degree. to 200.degree. C. The hemostat is swellable upon contact with blood. In use, the hemostat readily adapts to the shape of the hemorrhagic site, has an adhesiveness to a bleeding surface and provides an effective suppression of hemorrhage.

摘要翻译： PCT No.PCT / JP93 / 01587 Sec。 371日期1995年04月26日 102（e）日期1995年4月26日PCT 1993年11月2日PCT公布。 公开号WO94 / 09831 日期1994年5月11日含有纤维缠结的可吸收纺丝，棉状局部止血剂，由通过重构溶解胶原得到的胶原蛋白制成。 每个纤维的直径为10至70μm，长度为3至70mn。 构成纤维的胶原分子的至少一部分在50〜200℃的温度下通过加热交联。止血剂在与血液接触时可膨胀。 在使用中，止血剂容易适应出血部位的形状，具有与出血表面的粘合性，并且能有效抑制出血。

公开(公告)号：US5084349A

公开(公告)日：1992-01-28

申请号：US403354

申请日：1989-09-06

申请人： Masatomi Sasaki ,  Hirotomo Morita ,  Hiroki Sakakibara ,  Makoto Saruhashi ,  Yutaka Matsumoto

发明人： Masatomi Sasaki ,  Hirotomo Morita ,  Hiroki Sakakibara ,  Makoto Saruhashi ,  Yutaka Matsumoto

IPC分类号： B01D69/02 ,  B01D69/08 ,  B01D71/10

CPC分类号： B01D69/02 ,  B01D69/08 ,  B01D71/10 ,  Y10T428/2935 ,  Y10T428/2975

摘要： The cellulosic hollow-fiber membranes of the invention are useful in fluid processing apparatus typically for artificial dialysis. Each fiber has a tubular microporous wall having micropores and defining a lumen. The micropores have an average pore diameter of about 55 to about 300 .ANG.. The cellulosic hollow fibers exhibit a percent removal of .beta..sub.2 -microglobulin through adsorption of up to 10% after a solution of 20 mg/l of .beta..sub.2 -microglobulin in water is circulated through the fiber lumen for 3 hours. They also exhibit a sufficient filtration fraction of .beta..sub.2 -microglobulin and a ultrafiltration rate to remove .beta..sub.2 -microglobulin from blood predominantly through filtration while preventing contamination of the membranes with .beta..sub.2 -microglobulin due to adsorption and controlling the amount of water removed from the blood. The fibers are prepraed by wet spinning a cellulosic spinning dope into a hollow fiber followed by washing, heat treatment, plasticizing, and drying.