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公开(公告)号:US11589785B2
公开(公告)日:2023-02-28
申请号:US17176976
申请日:2021-02-16
Applicant: Medtronic, Inc.
Inventor: David Probst , Randal Schulhauser , Patrick W. Kinzie , Jadin C. Jackson , Daniel Hahn
IPC: A61B5/1468 , A61B5/00 , A61N1/05 , A61K31/662 , A61M5/142 , A61N1/36
Abstract: An enzymatic sensor configured to determine the concentration of levodopa present in a sample according to a current or a resonant frequency produced in response to levodopa interactions with L-amino acid decarboxylase present in the sensor. A processor associated with the sensor determines levodopa concentration and produces dose recommendation or output according to levodopa concentration.
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公开(公告)号:US11529517B2
公开(公告)日:2022-12-20
申请号:US17036641
申请日:2020-09-29
Applicant: Medtronic, Inc.
Inventor: Jadin C. Jackson , Steven M. Goetz
Abstract: Devices, systems, and techniques are disclosed for managing electrical stimulation therapy and/or sensing of physiological signals such as brain signals. For example, a system may assist a clinician in identifying one or more electrode combinations for sensing a brain signal. In another example, a user interface may display brain signal information and values of a stimulation parameter at least partially defining electrical stimulation delivered to a patient when the brain signal information was sensed.
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公开(公告)号:US11315682B2
公开(公告)日:2022-04-26
申请号:US16735340
申请日:2020-01-06
Applicant: Medtronic, Inc.
Inventor: Robert A. Corey , Gregory J. Loxtercamp , Heather Diane Orser , Scott R. Stanslaski , Jadin C. Jackson
Abstract: Techniques are described for real-time phase detection. For the phase detection, a signal is correlated with a frequency component of a frequency band whose phase is being detected, and the correlation includes predominantly decreasing weighting of past portions of the signals.
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公开(公告)号:US20220032059A1
公开(公告)日:2022-02-03
申请号:US16945639
申请日:2020-07-31
Applicant: Medtronic, Inc.
Inventor: Rene A. Molina , Scott R. Stanslaski , Jadin C. Jackson , Christopher L. Pulliam , Eric J. Panken , Michelle A. Case , Abbey Beuning Holt Becker
Abstract: Devices, systems, and techniques are described for identifying stimulation parameter values based on electrical stimulation that induces dyskinesia for the patient. For example, a method may include controlling, by processing circuitry, a medical device to deliver electrical stimulation to a portion of a brain of a patient, receiving, by the processing circuitry, information representative of an electrical signal sensed from the brain after delivery of the electrical stimulation, determining, by the processing circuitry and from the information representative of the electrical signal, a peak in a spectral power of the electrical signal at a second frequency lower than a first frequency of the electrical stimulation, and responsive to determining the peak in the spectral power of the electrical signal at the second frequency, performing, by the processing circuitry, an action.
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公开(公告)号:US11135429B2
公开(公告)日:2021-10-05
申请号:US16395308
申请日:2019-04-26
Applicant: Medtronic, Inc.
Inventor: Eric J. Panken , Christopher L. Pulliam , Jadin C. Jackson , Yizi Xiao
IPC: A61B5/00 , A61B5/24 , A61B5/369 , A61N1/05 , A61N1/36 , A61N1/372 , G01B7/00 , G16H20/30 , G16H50/20 , G16H50/50
Abstract: Techniques are described to determine a location of at least one oscillatory signal source in a patient. Processing circuitry may determine expected electrical signal levels based on a hypothetical location of the at least one oscillatory signal source. Processing circuitry may determine the electrical signal levels and determine an error value based on the expected electrical signal levels and the determined electrical signal levels. Processing circuitry may adjust the hypothetical location of the at least one oscillatory signal source until the error value is less than or equal to a threshold value, including the example where the error value is minimized.
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公开(公告)号:US20210226471A1
公开(公告)日:2021-07-22
申请号:US17221465
申请日:2021-04-02
Applicant: Medtronic, Inc.
Inventor: Kunal Paralikar , Elizabeth A. Fehrmann , Venkat R. Gaddam , Boysie R. Morgan , David P. Olson , Jadin C. Jackson
Abstract: Devices, systems, and techniques for monitoring the temperature of a device used to charge a rechargeable power source are disclosed. Implantable medical devices may include a rechargeable power source that can be transcutaneously charged. The temperature of an external charging device and/or an implantable medical device may be monitored to control the temperature exposure to patient tissue during a charging session used to recharge the rechargeable power source. In one example, a temperature sensor may sense a temperature of an internal portion of a device, wherein the housing of the device is not directly thermally coupled to the temperature sensor. A temperature for the housing of the device may then be estimated based on the sensed temperature provided by the non-thermally coupled temperature sensor. A processor may then control charging of the rechargeable power source based on the determined temperature for the housing.
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公开(公告)号:US20200338351A1
公开(公告)日:2020-10-29
申请号:US16395308
申请日:2019-04-26
Applicant: Medtronic, Inc.
Inventor: Eric J. Panken , Christopher L. Pulliam , Jadin C. Jackson , Yizi Xiao
Abstract: Techniques are described to determine a location of at least one oscillatory signal source in a patient. Processing circuitry may determine expected electrical signal levels based on a hypothetical location of the at least one oscillatory signal source. Processing circuitry may determine the electrical signal levels and determine an error value based on the expected electrical signal levels and the determined electrical signal levels. Processing circuitry may adjust the hypothetical location of the at least one oscillatory signal source until the error value is less than or equal to a threshold value, including the example where the error value is minimized.
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公开(公告)号:US20200338350A1
公开(公告)日:2020-10-29
申请号:US16392129
申请日:2019-04-23
Applicant: Medtronic, Inc.
Inventor: Eric J. Panken , Jadin C. Jackson , Yizi Xiao , Christopher L. Pulliam
IPC: A61N1/36 , A61B5/00 , A61B5/0478 , A61N1/372 , A61N1/05
Abstract: Techniques are disclosed for using probabilistic entropy to select electrodes with fewer artifacts for controlling adaptive electrical neurostimulation. In one example, a plurality of electrodes sense bioelectrical signals of a brain of a patient. Processing circuitry determines, for each bioelectrical signal sensed at a respective electrode of the plurality of electrodes, a probabilistic entropy value of the bioelectrical signal. The processing circuitry compares each of the respective probabilistic entropy values of the bioelectrical signal to respective entropy threshold values and selects, based on the comparisons, a subset of electrodes of the plurality of electrodes. The processing circuitry controls, based on the bioelectrical signals sensed via respective electrodes of the subset of electrodes and excluding the bioelectrical signals of the plurality of bioelectrical signals sensed via respective electrodes not in the subset of electrodes, delivery of electrical stimulation therapy to the patient.
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公开(公告)号:US20200185093A1
公开(公告)日:2020-06-11
申请号:US16735340
申请日:2020-01-06
Applicant: Medtronic, Inc.
Inventor: Robert A. Corey , Gregory J. Loxtercamp , Heather Diane Orser , Scott R. Stanslaski , Jadin C. Jackson
Abstract: Techniques are described for real-time phase detection. For the phase detection, a signal is correlated with a frequency component of a frequency band whose phase is being detected, and the correlation includes predominantly decreasing weighting of past portions of the signals.
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公开(公告)号:US10554069B2
公开(公告)日:2020-02-04
申请号:US15843854
申请日:2017-12-15
Applicant: Medtronic, Inc.
Inventor: Kunal Paralikar , Elizabeth A. Fehrmann , Venkat R. Gaddam , Boysie Morgan , David P. Olson , Jadin C. Jackson
IPC: H02J7/00 , H02J50/10 , A61B5/00 , A61M25/00 , A61N1/378 , G01K7/00 , G01K13/00 , H02J7/02 , A61N1/36 , A61N1/372
Abstract: Devices, systems, and techniques for monitoring the temperature of a device used to charge a rechargeable power source are disclosed. Implantable medical devices may include a rechargeable power source that can be transcutaneously charged. The temperature of an external charging device and/or an implantable medical device may be monitored to control the temperature exposure to patient tissue during a charging session used to recharge the rechargeable power source. In one example, a temperature sensor may sense a temperature of an internal portion of a device, wherein the housing of the device is not directly thermally coupled to the temperature sensor. A temperature for the housing of the device may then be estimated based on the sensed temperature provided by the non-thermally coupled temperature sensor. A processor may then control charging of the rechargeable power source based on the determined temperature for the housing.
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