NOVEL RNA-GUIDED DNA NUCLEASES AND USES THEREOF

    公开(公告)号:US20180362943A1

    公开(公告)日:2018-12-20

    申请号:US15766662

    申请日:2016-10-07

    Abstract: Provided herein are systems, methods, and compositions for the modification of target DNA sequences. More particularly, systems, methods, and compositions for cleaving a target DNA in eukaryotic cells with a guide RNA capable of hybridizing with a target sequence and an RNA-guided DNA nuclease are provided. Also provided are vectors and vector systems which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods for identifying and validating novel CRISPR systems.

    Plant regulatory elements and uses thereof

    公开(公告)号:US10351866B2

    公开(公告)日:2019-07-16

    申请号:US15602069

    申请日:2017-05-22

    Abstract: The invention provides recombinant DNA molecules and constructs, as well as their nucleotide sequences, useful for modulating gene expression in plants. The invention also provides transgenic plants, plant cells, plant parts, and seeds comprising the recombinant DNA molecules operably linked to heterologous transcribable DNA molecules, as are methods of their use.

    PLANT REGULATORY ELEMENTS AND USES THEREOF
    40.
    发明申请
    PLANT REGULATORY ELEMENTS AND USES THEREOF 审中-公开
    植物调节因子及其用途

    公开(公告)号:US20140283200A1

    公开(公告)日:2014-09-18

    申请号:US14205251

    申请日:2014-03-11

    Abstract: The invention provides recombinant DNA molecules and constructs, as well as their nucleotide sequences, useful for modulating gene expression in plants. The invention also provides transgenic plants, plant cells, plant parts, and seeds comprising a recombinant DNA molecule comprising a DNA molecule operably linked to heterologous transcribable DNA molecule, as are methods of their use.

    Abstract translation: 本发明提供了可用于调节植物中基因表达的重组DNA分子和构建体及其核苷酸序列。 本发明还提供转基因植物,植物细胞,植物部分和种子,其包含与异源可转录DNA分子可操作地连接的DNA分子的重组DNA分子,以及它们的使用方法。

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