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公开(公告)号：US12077770B2
公开(公告)日：2024-09-03
申请号：US17689613
申请日：2022-03-08
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Larry A. Gilbertson , David K. Kovalic , Thomas J. Larosa , Maolong Lu , Tichafa R. I. Munyikwa , James K. Roberts , Wei Wu , Bei Zhang
CPC classification number: C12N15/8286 , A01N63/50 , A01N63/60 , C12N15/8275 , C12N15/8279 , C12N15/8285 , Y02A40/146
Abstract: The present invention is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The invention discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.
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32.发明公开公开(公告)号：US20240117373A1
公开(公告)日：2024-04-11
申请号：US18490545
申请日：2023-10-19
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Claire A. CaJacob , Pascale Feldmann , Gregory R. Heck , Irene Maria Antonia Nooren , Geert Plaetinck , Wendy T. Maddelein , Ty T. Vaughn
IPC: C12N15/82 , C07H21/04 , C07K14/435 , C12N15/113
CPC classification number: C12N15/8286 , C07H21/04 , C07K14/43536 , C07K14/43563 , C12N15/113 , C12N15/8218 , C12N15/8282 , C12N15/8285 , Y02A40/146
Abstract: The present invention relates to control of pest infestation by inhibiting one or more biological functions. The invention provides methods and compositions for such control, By feeding one or more recombinant double stranded RNA molecules provided by the invention to the pest, a reduction in pest infestation is obtained through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.
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公开(公告)号：US11685930B2
公开(公告)日：2023-06-27
申请号：US16988589
申请日：2020-08-07
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Larry A. Gilbertson , David K. Kovalic , Thomas J. LaRosa , Maolong Lu , Tichafa R. I. Munyikwa , James K. Roberts , Wei Wu , Bei Zhang
CPC classification number: C12N15/8286 , A01N63/50 , A01N63/60 , C12N15/8275 , C12N15/8279 , C12N15/8285 , Y02A40/146 , A01N63/50 , A01N63/23
Abstract: The present invention is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The invention discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.
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公开(公告)号：US20220315945A1
公开(公告)日：2022-10-06
申请号：US17729892
申请日：2022-04-26
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Claire A. CaJacob , Pascale Feldman , Gregory R. Heck , Irene Maria Antonia Nooren , Geert Plaetinck , Wendy T. Maddelein , Ty T. Vaughn
IPC: C12N15/82 , C07H21/04 , C07K14/435 , C12N15/113
Abstract: The present invention relates to control of pest infestation by inhibiting one or more biological functions. The invention provides methods and compositions for such control, By feeding one or more recombinant double stranded RNA molecules provided by the invention to the pest, a reduction in pest infestation is obtained through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.
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公开(公告)号：US20220306703A1
公开(公告)日：2022-09-29
申请号：US17671011
申请日：2022-02-14
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas A. Cerruti , Crystal L. Dart , Leigh H. English , Stanislaw Flasinski , Xiaoran Fu , Victor M. Guzov , Arlene R. Howe , Jay P. Morgenstern , James K. Roberts , Sara A. Salvador , Jinling Wang
IPC: C07K14/325 , C12N15/82
Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
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Patent Agency Ranking
公开(公告)号：US11091770B2
公开(公告)日：2021-08-17
申请号：US15300661
申请日：2015-03-27
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Brian D. Eads , Jeremy A. Kroemer , Christina Marie Taylor
Abstract: Disclosed herein are methods of controlling insect pests which infest crop plants, in particular Spodoptera frugiperda (fall armyworm), Lygus hesperus (western tarnished plant bug), Euschistus heros (neotropical brown stink bug), and Plutella xylostella (diamondback moth), and methods of providing plants resistant to such pests. Also disclosed are polynucleotides and recombinant DNA molecules and constructs useful in such methods, insecticidal compositions such as topical sprays containing insecticidal double-stranded RNAs, and plants with improved resistance to infestation by these insects. Further disclosed are methods of selecting target genes for RNAi-mediated silencing and control of these insect pests.
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公开(公告)号：US20200002719A1
公开(公告)日：2020-01-02
申请号：US16573538
申请日：2019-09-17
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas Cerruti , Stanislaw Flasinski , Xiaoran Fu , Arlene R. Howe , Sara Ann Salvador
IPC: C12N15/82 , C07K14/325 , A01N47/08 , A01N63/02
Abstract: Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to the naturally occurring Cry1Da protein toxin. Polynucleotide sequences intended for use in expression of the improved proteins in plants are also provided. Particular embodiments provide compositions containing insect inhibitory amounts of the engineered proteins, as well as recombinant plants, plant parts, and seeds containing polynucleotide constructs encoding one or more of the improved engineered proteins.
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公开(公告)号：US20180334684A1
公开(公告)日：2018-11-22
申请号：US16047187
申请日：2018-07-27
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas Cerruti , Stanislaw Flasinski , Xiaoran Fu , Arlene R. Howe , Sara Ann Salvador
IPC: C12N15/82 , A01N63/02 , C07K14/325 , A01N47/08
Abstract: Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to the naturally occurring Cry1Da protein toxin. Polynucleotide sequences intended for use in expression of the improved proteins in plants are also provided. Particular embodiments provide compositions containing insect inhibitory amounts of the engineered proteins, as well as recombinant plants, plant parts, and seeds containing polynucleotide constructs encoding one or more of the improved engineered proteins.
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公开(公告)号：US10059959B2
公开(公告)日：2018-08-28
申请号：US14884432
申请日：2015-10-15
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas Cerruti , Stanislaw Flasinski , Xiaoran Fu , Arlene R. Howe , Sara Ann Salvador
Abstract: Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to the naturally occurring Cry1Da protein toxin. Polynucleotide sequences intended for use in expression of the improved proteins in plants are also provided. Particular embodiments provide compositions containing insect inhibitory amounts of the engineered proteins, as well as recombinant plants, plant parts, and seeds containing polynucleotide constructs encoding one or more of the improved engineered proteins.
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公开(公告)号：US20180127774A1
公开(公告)日：2018-05-10
申请号：US15849012
申请日：2017-12-20
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas A. Cerruti , Crystal L. Dart , Leigh H. English , Stanislaw Flasinski , Xiaoran Fu , Victor M. Guzov , Arlene R. Howe , Jay P. Morgenstern , James K. Roberts , Sara A. Salvador , Jinling Wang
IPC: C12N15/82
Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
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