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45 条记录 (耗时 0.03 秒)

    POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING SAME
    31.
    发明申请
    POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING SAME 审中-公开
    聚合物化合物和发光装置

    公开(公告)号：US20140183414A1

    公开(公告)日：2014-07-03

    申请号：US14238892

    申请日：2012-08-10

    申请人： Yoshikazu Umemoto ,  Tomoya Nakatani

    发明人： Yoshikazu Umemoto ,  Tomoya Nakatani

    IPC分类号： H01L51/00

    CPC分类号： H01L51/0043 ,  C08G61/12 ,  C08G2261/124 ,  C08G2261/148 ,  C08G2261/3142 ,  C08G2261/3162 ,  C08G2261/411 ,  C08G2261/512 ,  C08G2261/5222 ,  C08G2261/95 ,  C08L65/00 ,  C08L2205/02 ,  H01L51/0035 ,  H01L51/0039 ,  H01L51/5012

    摘要： A polymer compound comprising a repeating unit represented by the formula (1): wherein, E1, E2, E3 and E4 represent each independently an aryl group, a mono-valent heterocyclic group or the like, a, b, c, d and e represent each independently 1 or 2, and f represents an integer of 0 to 3, and when f=0, then, 5≦a+b+c+e≦8 and at least one of b and c is 2, and when there are a plurality of d, these may be the same or different, m, n, o, p, q and l represent each independently an integer of 0 to 4, and when there are a plurality of m, n, o, p and q, these may be the same or different, respectively, j and k represent each independently an integer of 0 to 5.

    摘要翻译： 一种包含式（1）表示的重复单元的高分子化合物：其中，E1，E2，E3和E4各自独立地表示芳基，1价杂环基等，a，b，c，d和e 每个独立地表示1或2，f表示0〜3的整数，当f = 0时，5＆lt; 1lE; a + b + c + e＆nlE; 8，b和c中的至少一个为2， 是多个d，它们可以相同或不同，m，n，o，p，q和l各自独立地表示0〜4的整数，当有多个m，n，o，p和 q，这些可以分别相同或不同，j和k各自独立地表示0〜5的整数。

    Specific marker Lmx1a on dopaminergic neurons
    32.
    发明授权
    Specific marker Lmx1a on dopaminergic neurons 有权
    多巴胺能神经元上的特异性标记物Lmx1a

    公开(公告)号：US08187804B2

    公开(公告)日：2012-05-29

    申请号：US10580989

    申请日：2004-11-26

    申请人： Yuichi Ono ,  Yasuko Nakagawa ,  Tomoya Nakatani

    发明人： Yuichi Ono ,  Yasuko Nakagawa ,  Tomoya Nakatani

    IPC分类号： C12Q1/68 ,  G01N33/53

    CPC分类号： C12Q1/6881 ,  C12Q1/6883 ,  C12Q2600/158 ,  G01N33/6896 ,  G01N33/9413 ,  G01N2800/2835

    摘要： The present invention identified Lmx1a genes, which are expressed in dopaminergic neurons at all differentiation stages, from proliferating dopaminergic neuron progenitor cells before cell cycle exit to cells after cell cycle exit. Lmx1a expression in cells can be used as an indicator when selecting cells suitable for transplantation therapy for neurodegenerative diseases such as Parkinson's disease, and is useful as a marker for screening agents involved in the induction of dopaminergic neuron differentiation.

    摘要翻译： 本发明鉴定了在细胞周期退出至细胞周期后出现的细胞周期性增殖的多巴胺能神经元祖细胞中，在所有分化阶段的多巴胺能神经元中表达的Lmx1a基因。 当选择适合于帕金森病等神经变性疾病的移植治疗的细胞时，细胞中的Lmx1a表达可用作指示剂，并且可用作参与多巴胺能神经元分化诱导的筛选剂的标记。

    DOPAMINERGIC NEURON PROLIFERATIVE PROGENITOR CELL MARKER Msx1/2
    33.
    发明申请
    DOPAMINERGIC NEURON PROLIFERATIVE PROGENITOR CELL MARKER Msx1/2 审中-公开
    多巴胺神经元增殖性前体细胞标记Msx1 / 2

    公开(公告)号：US20110229889A1

    公开(公告)日：2011-09-22

    申请号：US13071450

    申请日：2011-03-24

    申请人： Yuichi Ono ,  Yasuko Nakagawa ,  Tomoya Nakatani ,  Yoshimasa Sakamoto

    发明人： Yuichi Ono ,  Yasuko Nakagawa ,  Tomoya Nakatani ,  Yoshimasa Sakamoto

    IPC分类号： C12Q1/68 ,  C07H21/00

    CPC分类号： G01N33/56966 ,  C07K16/18 ,  C12Q1/6881 ,  C12Q2600/158

    摘要： The present invention is a probe, a primer, and an antibody, for detecting a dopaminergic neuron proliferative progenitor cell. According to the present invention, there is provided a polynucleotide probe and a polynucleotide primer for use in the detection or selection of a dopaminergic neuron proliferative progenitor cell, which can hybridize with a polynucleotide consisting of a nucleotide sequence of an Msx1 gene or an Msx2 gene, or a complementary sequence thereto, and an antibody against an Msx1 protein or an Msx2 protein, or a part thereof for use in the detection or selection of a dopaminergic neuron proliferative progenitor cell.

    摘要翻译： 本发明是用于检测多巴胺能神经元增殖祖细胞的探针，引物和抗体。 根据本发明，提供了用于检测或选择多巴胺能神经元增殖祖细胞的多核苷酸探针和多核苷酸引物，其可以与由Msx1基因或Msx2基因的核苷酸序列组成的多核苷酸杂交 ，或其互补序列，以及针对用于检测或选择多巴胺能神经元增殖祖细胞的Msx1蛋白或Msx2蛋白或其一部分的抗体。

    COMPOUND CONTAINING 1,3-DIENE STRUCTURE AND METHOD FOR PRODUCING SAME
    34.
    发明申请
    COMPOUND CONTAINING 1,3-DIENE STRUCTURE AND METHOD FOR PRODUCING SAME 有权
    含有1,3-二烯结构的化合物及其生产方法

    公开(公告)号：US20110127517A1

    公开(公告)日：2011-06-02

    申请号：US13056257

    申请日：2009-07-29

    申请人： Tomoya Nakatani

    发明人： Tomoya Nakatani

    IPC分类号： H01L51/52 ,  C07C25/24 ,  C07C43/225 ,  C07D307/91 ,  C08G79/08 ,  C09K11/06

    CPC分类号： C07C17/269 ,  C07C41/16 ,  C07C43/225 ,  C07C2603/18 ,  C08G61/02 ,  C08G61/12 ,  C08G61/126 ,  C08G2261/135 ,  C08G2261/15 ,  C08G2261/312 ,  C08G2261/3142 ,  C08G2261/3162 ,  C08G2261/3241 ,  C08G2261/3243 ,  C08G2261/51 ,  C09K11/06 ,  C09K2211/1416 ,  C09K2211/1425 ,  C09K2211/1433 ,  C09K2211/1458 ,  C09K2211/1466 ,  H01L51/0035 ,  H01L51/0036 ,  H01L51/0039 ,  H01L51/0042 ,  H01L51/0094 ,  H01L51/5048 ,  H05B33/14 ,  Y10S428/917

    摘要： Disclosed is a compound containing a divalent group represented by formula (I). (In formula (I), Ar1 represents an arylene group, a divalent heterocyclic group or a divalent aromatic amine group; J1 represents a phenylene group; J2 represents an alkylene group; X represents an oxygen atom or a sulfur atom; j represents 0 or 1, k represents an integer of 0-3, and l represents 0 or 1, while satisfying 1≦j+k+l≦5; m represents 1 or 2; R1 represents a hydrogen atom, an alkyl group, an alkoxy group, an alkylthio group, an aryl group, an aryloxy group, an arylthio group, an arylalkyl group, an arylalkoxy group, an arylalkylthio group, an arylalkenyl group, an arylalkynyl group, an amino group, a substituted amino group, a silyl group, a substituted silyl group, a halogen atom, an acyl group, an acyloxy group, an imine residue, a carbamoyl group, an acid imide group, a monovalent heterocyclic group, a carboxyl group, a substituted carboxyl group, a cyano group or a nitro group; the plurality of R1's may be the same as or different from each other; and when there are a plurality of J1's, J2's, X's, j's, k's or l's, the J1's, J2's, X's, j's, k's or l's may be the same as or different from each other, respectively.)

    摘要翻译： 公开了含有式（I）表示的二价基团的化合物。 （式（I）中，Ar 1表示亚芳基，2价杂环基或2价芳香族胺基，J 1表示亚苯基，J2表示亚烷基，X表示氧原子或硫原子，j表示0或 1，k表示0-3的整数，l表示0或1，同时满足1＆nlE; j + k + 1＆nlE; 5; m表示1或2; R1表示氢原子，烷基，烷氧基， 烷硫基，芳基，芳氧基，芳硫基，芳基烷基，芳基烷氧基，芳基烷硫基，芳基烯基，芳基炔基，氨基，取代氨基，甲硅烷基， 取代甲硅烷基，卤素原子，酰基，酰氧基，亚胺残基，氨基甲酰基，酰亚胺基，1价杂环基，羧基，取代羧基，氰基或硝基 ;多个R1可以彼此相同或不同;并且当有一个 重新分配J1，J2，X，J，K或I，J1，J2，X，J，K或者可以分别相同或不同。

    SPECIFIC MARKER Lmx1a ON DOPAMINERGIC NEURONS
    40.
    发明申请
    SPECIFIC MARKER Lmx1a ON DOPAMINERGIC NEURONS 有权
    特异性标记Lmx1a在多巴胺神经元上

    公开(公告)号：US20120178083A1

    公开(公告)日：2012-07-12

    申请号：US13352241

    申请日：2012-01-17

    申请人： Yuichi Ono ,  Yasuko Nakagawa ,  Tomoya Nakatani

    发明人： Yuichi Ono ,  Yasuko Nakagawa ,  Tomoya Nakatani

    IPC分类号： C12Q1/68 ,  C07K16/18 ,  G01N33/566

    CPC分类号： C12Q1/6881 ,  C12Q1/6883 ,  C12Q2600/158 ,  G01N33/6896 ,  G01N33/9413 ,  G01N2800/2835

    摘要： The present invention identified Lmx1a genes, which are expressed in dopaminergic neurons at all differentiation stages, from proliferating dopaminergic neuron progenitor cells before cell cycle exit to cells after cell cycle exit. Lmx1a expression in cells can be used as an indicator when selecting cells suitable for transplantation therapy for neurodegenerative diseases such as Parkinson's disease, and is useful as a marker for screening agents involved in the induction of dopaminergic neuron differentiation.

    摘要翻译： 本发明鉴定了在细胞周期退出至细胞周期后出现的细胞周期性增殖的多巴胺能神经元祖细胞中，在所有分化阶段的多巴胺能神经元中表达的Lmx1a基因。 当选择适合于帕金森病等神经变性疾病的移植治疗的细胞时，细胞中的Lmx1a表达可用作指示剂，并且可用作参与多巴胺能神经元分化诱导的筛选剂的标记。