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31.发明授权
公开(公告)号：US5735859A
公开(公告)日：1998-04-07
申请号：US800613
申请日：1997-02-14
摘要： The present invention is a device and method for securing and releasing the distal end of a thin-walled sheath to and from a distal section of a stent delivery catheter. The invention comprises a stent delivery catheter system which includes a sheath which is releasably attached to a distal section of a stent delivery catheter. When the stent delivery system has been advanced into the body so that the stent (which is situated coaxially within the sheath) is placed at the site of an arterial stenosis where it is to be deployed, the sheath is released from the stent delivery catheter and then the sheath is pulled back in a proximal direction thereby uncovering the stent. Self-deploying stents will automatically deploy when the sheath is pulled back. Balloon expandable stents can be deployed by balloon inflation after the sheath has been pulled back. One embodiment of the distally attachable and releasable sheath utilizes a guide wire that passes through the stent delivery catheter first to hold and then to release the distal end of the sheath from a distal section of the stent delivery catheter.
摘要翻译： 本发明是一种用于将薄壁护套的远端固定并释放到支架输送导管的远端部分的装置和方法。 本发明包括支架递送导管系统，其包括可释放地附接到支架递送导管的远端部分的护套。 当支架输送系统已经进入体内，使得支架（其位于鞘内同轴位置）被放置在其将要部署的动脉狭窄部位时，护套从支架输送导管释放，并且 然后将护套沿近侧方向拉回，从而露出支架。 当护套被拉回时，自动部署支架将自动部署。 护套被拉回之后，球囊扩张支架可以通过球囊膨胀进行部署。 远端可附接和可释放的护套的一个实施例使用导线首先穿过支架输送导管以保持，然后从支架输送导管的远端部分释放护套的远端。
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公开(公告)号：US5695516A
公开(公告)日：1997-12-09
申请号：US604682
申请日：1996-02-21
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91541 , A61F2002/91558 , A61F2002/91566 , A61F2250/0067 , A61F2310/00131 , A61F2310/00155
摘要： The present invention is designed to overcome several disadvantages of prior art balloon expandable stents. Specifically, the Butterfly Expandable To Honeycomb (BETH) stent described herein consists of a collection of circumferential (or vertical) arc structures and diagonal struts. These arcs and struts form a butterfly shape before the stent is expanded and a hexagonal, honeycomb type of structure is created when the stent is fully expanded. Until the nominal stent diameter is reached, the deployed length of the stent is actually longer than the non-deployed length. At the nominal fully-deployed diameter, the deployed stent is exactly the same length as the non-deployed length. This characteristic provides better assurance of completely covering a dilated stenosis as compared to a stent that shortens in length when deployed as is typical of all prior art balloon expandable stents. Furthermore, because at least one quarter of the expanded stent's circumference consist of vertical arcs that are arcs of a circle, they provide the BETH stent with improved radial rigidity.
摘要翻译： 本发明被设计为克服现有技术的球囊可扩张支架的若干缺点。 具体来说，本文所述的蝴蝶展开型蜂窝（BETH）支架由周向（或垂直）弧形结构和对角支柱的集合组成。 这些弧形和支柱在支架膨胀之前形成蝴蝶形状，并且当支架完全展开时产生六边形蜂窝型结构。 直到达到标称支架直径，支架的展开长度实际上比非展开长度长。 在标称完全直径的情况下，展开的支架的长度与未展开的长度完全相同。 与所有现有技术的球囊可扩张支架的典型部署时相比，当展开长度缩短的支架时，该特征提供了完全覆盖扩张狭窄的更好的保证。 此外，因为扩张支架的圆周的至少四分之一由垂直圆弧组成，它们是圆弧，它们为BETH支架提供了改进的径向刚度。
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公开(公告)号：US5605530A
公开(公告)日：1997-02-25
申请号：US408780
申请日：1995-03-23
CPC分类号： A61N5/1002 , A61F2/95 , A61F2/0095 , A61N2005/1094 , A61N5/1007
摘要： There is provided a radiation shield for protecting a health care worker from ionizing radiation prior to and during delivery of a radioisotope stent into a patient's blood vessel. The radiation shield is placed coaxially over at least a distal portion of a stent delivery catheter assembly carrying or having formed therein a radioactive stent. The radiation shield is maintained about the distal portion of the catheter assembly until delivery of the radioactive stent is to occur. During the stent's delivery, the catheter assembly is axially displaced relative to the radiation shield to pass therethrough, then into the patient's blood vessel. A protective barrier is thus continually maintained between the health care worker and the radioactive stent he or she is delivering.
摘要翻译： 提供了辐射屏蔽，用于在将放射性同位素支架输送到患者血管之前和期间保护医护人员免受电离辐射。 辐射屏蔽同轴地放置在支架输送导管组件的至少一个远端部分上，该导管组件携带或已经形成放射性支架。 辐射屏蔽围绕导管组件的远端部分保持，直到发生放射性支架的输送。 在支架的输送期间，导管组件相对于辐射屏蔽件轴向移位，从而穿过其中，然后进入患者的血管。 因此，保健工作者和他或她正在投放的放射性支架之间持续保持保护屏障。
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公开(公告)号：US5409454A
公开(公告)日：1995-04-25
申请号：US236249
申请日：1994-05-02
申请人： Robert E. Fischell , James J. Thompson , David R. Fischell , Richard L. Harding , Tim A. Fischell
发明人： Robert E. Fischell , James J. Thompson , David R. Fischell , Richard L. Harding , Tim A. Fischell
CPC分类号： A61B17/320783 , A61B2017/22038 , A61B2017/22051 , A61B2017/320052
摘要： A catheter is disclosed which is capable of cutting obstructive tissue from a vessel of a living body while shielding a portion of the wall of the vessel from being exposed to the cutting blade at the catheter's distal end. An essentially continuous outer surface at the catheter's distal end allows it to be readily advanced through an introducer sheath and through a tight stenosis in an artery. The shield at the catheter's distal end could subtend an arc from as little as 45 degrees to as large as 270 degrees depending on the extent of the vessel wall that is to be protected from being cut. A vacuum source at the catheter's proximal end can cause a suction to exist at a cutout at the catheter's distal end in order to pull obstructive tissue into the cutout as the cutting cylinder is pulled back in a retrograde direction, this suction being capable of enhancing the removal of the obstructive tissue.
摘要翻译： 公开了一种导管，其能够屏蔽来自血管的容器的阻塞性组织，同时屏蔽该容器的壁的一部分在导管远端暴露于切割刀片。 在导管的远端处基本上连续的外表面允许其容易地推进穿过导引鞘并且通过动脉中的狭窄狭窄。 导管远端的护罩可以根据待保护的血管壁的切割程度，从45度到270度的弧度相对应。 在导管的近端处的真空源可以导致在导管远端的切口处存在抽吸，以便当切割圆筒沿逆行方向被拉回时将阻塞性组织拉入切口，该吸力能够增强 去除阻塞性组织。
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公开(公告)号：US5389090A
公开(公告)日：1995-02-14
申请号：US192347
申请日：1994-02-07
IPC分类号： A61M25/06 , A61M25/088 , A61M25/00
CPC分类号： A61M25/0662
摘要： A guiding catheter system (10) is provided that includes a Tuohy-Borst fitting (20) attached as a one-piece construction to a guiding catheter tube (11). The guiding catheter system (10) can also include a dilator (16) and a guide wire 15. The Tuohy-Borst fitting (20) can have a side arm (14) onto which a stop cock (30) can be attached. With the stop cock (30) in its closed position, fluid flow through the side arm (14) is prevented. When the nut (22) on the Tuohy-Borst fitting (20) is tightened down so that the gland (24) in the Tuohy-Borst fitting (20) seals against the guide wire (15) and the stop cock (30) is closed, blood loss through the proximal end of the guiding catheter system (10) can be essentially eliminated. Since the Tuohy-Borst fitting (20) is integrally joined to the proximal end of the guiding catheter tube (11), the need for a separately packaged and sterilized Tuohy-Borst fitting to be screwed onto the guiding catheter's proximal end is eliminated. The dilator (16) with the guide wire (15) can be used to allow percutaneous insertion of the guiding catheter system (10) into a patient's artery without requiring an introducer sheath, thus reducing the size of the hole that is made in the wall of the artery. A smaller hole in the artery's wall reduces the possibility of post-procedure bleeding at that point where the guiding catheter system (10) is inserted.
摘要翻译： 提供了一种引导导管系统（10），其包括以引导导管（11）作为一体结构附接的Tuohy-Borst配件（20）。 引导导管系统（10）还可以包括扩张器（16）和导丝15. Tuohy-Borst配件（20）可以具有侧臂（14），可以在其上安装止动旋塞（30）。 在停止旋塞（30）处于其关闭位置时，流体流过侧臂（14）被阻止。 当Tuohy-Borst配件（20）上的螺母（22）拧紧时，Tuohy-Borst配件（20）中的压盖（24）密封在导丝（15）上，止动螺母（30）是 可以基本上消除通过引导导管系统（10）的近端的失血。 由于Tuohy-Borst配件（20）与引导导管（11）的近端整体连接，所以不需要将单独包装的灭菌的Tuohy-Borst配件拧入导向导管的近端。 具有引导线（15）的扩张器（16）可以用于允许引导导管系统（10）经皮插入病人的动脉中，而不需要引导器护套，从而减小在壁中形成的孔的尺寸 的动脉。 动脉壁上的一个较小的孔减少了引导导管系统（10）插入的那一点的手术后出血的可能性。
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公开(公告)号：US5334187A
公开(公告)日：1994-08-02
申请号：US98439
申请日：1993-07-28
CPC分类号： A61M25/0169 , A61M25/0172 , A61M25/104 , A61M2025/0183 , A61M2025/107
摘要： A balloon angioplasty catheter system comprising a flexible guide wire, balloon catheter and slide handle. The balloon catheter has a shaft with a guide wire lumen that includes a guide wire removal slit which extends along a portion of the shaft. The slide handle is configured to open the slit as the handle slides along the catheter. The handle includes a separate passage for the catheter and guide wire and is provided with a fitting for connecting the handle to the "Y" adaptor of a guide catheter. The system provides a arrangement with the advantages of both an over-the-wire and monorail catheter.
摘要翻译： 一种球囊血管成形术导管系统，包括柔性导丝，球囊导管和滑动手柄。 气囊导管具有带有导丝管腔的轴，其包括沿轴的一部分延伸的导丝线移除狭缝。 滑动手柄构造成当手柄沿着导管滑动时打开狭缝。 手柄包括用于导管和导丝的独立通道，并且设置有用于将手柄连接到导向导管的“Y”适配器的配件。 该系统提供了具有超线和单轨导管两者优点的布置。
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公开(公告)号：US09101278B2
公开(公告)日：2015-08-11
申请号：US13025476
申请日：2011-02-11
IPC分类号： A61B5/0452 , A61B5/0468 , A61B5/00
CPC分类号： A61B5/02455 , A61B5/0031 , A61B5/04012 , A61B5/0422 , A61B5/0452 , A61B5/0456 , A61B5/0468 , A61B5/0472 , A61B5/746 , A61B5/7465 , A61B2560/0209
摘要： Disclosed is a system for the detection of cardiac events (a guardian system) that includes an implanted device called a cardiosaver, a physician's programmer and an external alarm system. The system is designed to provide early detection of cardiac events such as acute myocardial infarction or exercise induced myocardial ischemia caused by an increased heart rate or exertion. The system can also alert the patient with a less urgent alarm if a heart arrhythmia is detected. Using one or more detection algorithms, the cardiosaver can detect a change in the patient's electrogram that is indicative of a cardiac event within five minutes after it occurs and then automatically warn the patient that the event is occurring. To provide this warning, the guardian system includes an internal alarm sub-system (internal alarm means) within the cardiosaver and/or an external alarm system (external alarm means). If the guardian system is put into a pacemaker, the algorithm can utilize a different analysis of the electrogram depending on whether or not the pacemaker is actually pacing the heart.
摘要翻译： 公开了一种用于检测心脏事件（监护系统）的系统，其包括称为心脏切除器的植入装置，医师编程器和外部警报系统。 该系统旨在提供心脏事件的早期检测，例如由心率增加或运动引起的急性心肌梗死或运动诱发的心肌缺血。 如果检测到心律失常，该系统还可以警告患者不太紧急的警报。 使用一个或多个检测算法，心脏扫描器可以检测患者的电描记图中的变化，其指示在发生后五分钟内的心脏事件，然后自动向患者发出事件发生。 为了提供此警告，监护系统包括在心脏保护器内和/或外部报警系统（外部报警装置）内的内部报警子系统（内部报警装置）。 如果将监护人系统放入心脏起搏器，该算法可以根据起搏器是否实际起搏心脏，对电图进行不同的分析。
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公开(公告)号：US08747452B2
公开(公告)日：2014-06-10
申请号：US12286558
申请日：2008-09-30
IPC分类号： A61F2/82
CPC分类号： A61F2/844 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/825 , A61F2002/91533 , A61F2002/9155 , A61F2210/0019
摘要： A method for implanting a balloon expandable stent at a site within a passageway of a curved coronary article. The stent includes at least two longitudinally spaced apart circumferential rings. At least one longitudinally extending connector extends between adjacent rings. The connector has at least one turn back portion that can expand or contract in length while being passed through a curved passageway. The stent is disposed on a stent delivery catheter having an inflatable balloon. The stent delivery catheter and the stent is delivered through the passageway to the site of implementation with the connector member expanding or contracting in length to facilitate delivery and placement of the stent. The stent is expanded at the site of implantation by inflating the balloon to force the stent radially outward against the wall of the coronary artery.
摘要翻译： 一种用于将球囊可扩张支架植入弯曲冠状动脉制品通道内的部位的方法。 支架包括至少两个纵向间隔开的周向环。 至少一个纵向延伸的连接器在相邻的环之间延伸。 连接器具有至少一个回转部分，其能够在穿过弯曲通道的同时膨胀或收缩。 支架设置在具有可膨胀气囊的支架输送导管上。 支架输送导管和支架通过通道被输送到实现位置，连接器构件的长度膨胀或收缩以便于支架的输送和放置。 通过使气囊膨胀来使支架在植入部位扩张，以使支架径向向外抵靠冠状动脉壁。
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公开(公告)号：US08630702B2
公开(公告)日：2014-01-14
申请号：US11594806
申请日：2006-11-09
申请人： David R. Fischell , Tim A. Fischell , Jonathan Harwood , Robert E. Fischell , Steven R. Johnson , Bruce Hopenfeld , Michael Sasha John
发明人： David R. Fischell , Tim A. Fischell , Jonathan Harwood , Robert E. Fischell , Steven R. Johnson , Bruce Hopenfeld , Michael Sasha John
IPC分类号： A61B5/0452
CPC分类号： A61B5/0456 , A61B5/0006 , A61B5/0031 , A61B5/0452 , A61B5/046 , A61B5/0464 , A61B5/7465 , A61B2560/0209 , A61N1/3627 , A61N1/3702
摘要： A system for the detection of cardiac events occurring in a human patient is provided. At least two electrodes are included in the system for obtaining an electrical signal from a patient's heart. An electrical signal processor is electrically coupled to the electrodes for processing the electrical signal and a patient alarm means is further provided and electrically coupled to the electrical signal processor. The electrical signal is acquired in the form of electrogram segments, which are categorized according to heart rate, ST segment shift and type heart rhythm (normal or abnormal). Baseline electrogram segments are tracked over time.
摘要翻译： 提供了一种用于检测在人类患者中发生的心脏事件的系统。 系统中包括至少两个电极，以从患者的心脏获得电信号。 电信号处理器电耦合到电极以处理电信号，并且还提供患者报警装置并电耦合到电信号处理器。 电信号是以心律，ST段移位和心律（正常或异常）分为心电图段的形式获得的。 基线电描绘片段随时间跟踪。
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公开(公告)号：US08157856B2
公开(公告)日：2012-04-17
申请号：US11804710
申请日：2007-05-18
IPC分类号： A61F2/82
CPC分类号： A61F2/844 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/825 , A61F2002/91533 , A61F2002/9155 , A61F2210/0019
摘要： A method for implanting a balloon expandable stent at a site within a passageway of a curved coronary article. The stent includes at least two longitudinally spaced apart circumferential rings. At least one longitudinally extending connector extends between adjacent rings. The connector has at least one turn back portion that can expand or contract in length while being passed through a curved passageway. The stent is disposed on a stent delivery catheter having an inflatable balloon. The stent delivery catheter and the stent is delivered through the passageway to the site of implementation with the connector member expanding or contracting in length to facilitate delivery and placement of the stent. The stent is expanded at the site of implantation by inflating the balloon to force the stent radially outward against the wall of the coronary artery.
摘要翻译： 一种用于将球囊可扩张支架植入弯曲冠状动脉制品通道内的部位的方法。 支架包括至少两个纵向间隔开的周向环。 至少一个纵向延伸的连接器在相邻的环之间延伸。 连接器具有至少一个回转部分，其能够在穿过弯曲通道的同时膨胀或收缩。 支架设置在具有可膨胀气囊的支架输送导管上。 支架输送导管和支架通过通道被输送到实现位置，连接器构件的长度膨胀或收缩以便于支架的输送和放置。 通过使气囊膨胀来使支架在植入部位扩张，以使支架径向向外抵靠冠状动脉壁。
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