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31.发明授权Cancer therapy based on tumor associated antigens derived from cyclin D1 有权基于衍生自细胞周期蛋白D1的肿瘤相关抗原的癌症治疗公开(公告)号：US09056069B2
公开(公告)日：2015-06-16
申请号：US13150785
申请日：2011-06-01
申请人： Harpreet Singh , Toni Weinschenk , Steffen Walter
发明人： Harpreet Singh , Toni Weinschenk , Steffen Walter
IPC分类号： A61K39/00 , A61K38/20 , A61K38/21 , A61K45/06 , C07K14/47 , A61K31/404 , A61K31/44 , A61K31/675 , A61K39/39 , C12N5/0783 , A61K38/17 , A61K38/19
CPC分类号： A61K39/0011 , A61K31/404 , A61K31/44 , A61K31/675 , A61K38/1709 , A61K38/193 , A61K38/20 , A61K38/2013 , A61K38/2026 , A61K38/21 , A61K39/39 , A61K45/06 , C07K14/4738 , C12N5/0638 , G01N2800/24 , G01N2800/7028 , A61K2300/00
摘要： The present invention relates to cyclin D1-derived peptides for use in the improved treatment of cancer in a patient, particularly in the form of a combination therapy using a vaccine. Other aspects relate to the use of the peptides or a combination thereof as a diagnostic tool.
摘要翻译： 本发明涉及用于改善患者癌症治疗的细胞周期蛋白D1衍生肽，特别是以使用疫苗的组合疗法的形式。 其他方面涉及肽或其组合的用途作为诊断工具。
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32.发明申请公开(公告)号：US20130115188A1
公开(公告)日：2013-05-09
申请号：US13635898
申请日：2011-03-16
IPC分类号： A61K39/00
CPC分类号： A61K39/0011 , A61K2039/55511 , A61K2039/55522 , C07K14/4748 , G01N33/5005
摘要： The present invention relates to immunotherapeutic peptides and their use in immunotherapy, in particular the immunotherapy of cancer. The present invention discloses tumor-associated T-helper cell peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumor immune responses. In particular, the composition of the peptides of the present invention can be used in vaccine compositions for eliciting anti-tumor immune responses against gastric cancers (GC).
摘要翻译： 本发明涉及免疫治疗肽及其在免疫治疗中的用途，特别是癌症的免疫治疗。 本发明公开了肿瘤相关的T辅助细胞肽表位，其单独或与作为刺激抗肿瘤免疫应答的疫苗组合物的活性药物成分的其它肿瘤相关肽组合。 特别地，本发明的肽的组合物可用于引发针对胃癌（GC）的抗肿瘤免疫应答的疫苗组合物中。
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33.发明申请公开(公告)号：US20130045191A1
公开(公告)日：2013-02-21
申请号：US13635896
申请日：2011-03-15
IPC分类号： A61K35/26 , C07K7/08 , C07K14/725 , C12N5/0783 , A61P37/04 , A61P35/00 , C12N5/10 , C12P21/02 , C07K7/06 , C12N15/12
CPC分类号： A61K38/1709 , A61K39/0011 , A61K2039/5158 , A61K2039/572 , A61K2039/585 , A61P35/00 , C07K7/06 , C07K2319/00 , G01N33/505
摘要： The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to 95 novel peptide sequences and their variants derived from HLA class I molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
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公开(公告)号：US20110291557A1
公开(公告)日：2011-12-01
申请号：US13201225
申请日：2010-02-02
CPC分类号： H01J61/366 , H01J9/323
摘要： A high pressure discharge lamp may include a ceramic discharge vessel and a longitudinal axis, wherein at least one electrode is led out of the discharge vessel by means of a metal-containing feed-through, wherein the feed-through is connected to one end of the discharge vessel by way of a ceramic-containing adjustment part, wherein the adjustment part is tubular and consists of individual layers with different compositions, at least two materials A and B forming a plurality of layers of the adjustment part, these materials being chosen such that their coefficient of thermal expansion is between that of the feed-through and that of the end of the discharge vessel or at most is just outside, the layer thickness of each layer being so low that no shearing forces can occur, and the layer thickness of each layer of the same material being different.
摘要翻译： 高压放电灯可以包括陶瓷放电容器和纵向轴线，其中至少一个电极通过含金属的馈通引出放电容器，其中馈通连接到 所述放电容器通过含陶瓷的调节部件，其中所述调节部件是管状的，并且由具有不同成分的各个层组成，至少两种材料A和B形成所述调节部件的多个层，这些材料被选择为 它们的热膨胀系数在馈通和放电容器末端的热膨胀系数之间，或者至多在外侧，每层的层厚度如此之低，不会产生剪切力，层厚度 相同材料的每层不同。
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公开(公告)号：US20110248028A1
公开(公告)日：2011-10-13
申请号：US13140443
申请日：2009-11-11
IPC分类号： H01J61/30
CPC分类号： H01J61/302 , H01J9/247 , H01J61/073 , H01J61/82
摘要： In various embodiments, a discharge vessel for a high-pressure discharge lamp may include a plurality of parts from ceramic material, wherein the discharge vessel is made of at least two stacked layers.
摘要翻译： 在各种实施例中，用于高压放电灯的放电容器可以包括来自陶瓷材料的多个部件，其中放电容器由至少两个堆叠层制成。
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36.发明授权公开(公告)号：US08025203B2
公开(公告)日：2011-09-27
申请号：US12797846
申请日：2010-06-10
申请人： Rene Jabado , Ursus Krüger , Daniel Körtvelyessy , Ralph Reiche , Michael Rindler , Steffen Walter
发明人： Rene Jabado , Ursus Krüger , Daniel Körtvelyessy , Ralph Reiche , Michael Rindler , Steffen Walter
IPC分类号： B23K31/02
CPC分类号： B23K31/02 , B23K1/0018 , B23K35/0244 , B23K2101/001 , B23P6/005 , B23P6/007 , Y10T156/10 , Y10T428/12493 , Y10T428/249924
摘要： Short fibers in a solder or a welding material often do not have the desired strength. Fiber mats that are introduced onto a surface or into a recess of a metallic component are provided. In addition a process for applying material to a metallic component is provided. In the process, a first fiber mat and a second fiber mat are used.
摘要翻译： 焊料或焊接材料中的短纤维通常不具有所需的强度。 提供了引入到金属部件的表面或凹部中的纤维毡。 此外，提供了将材料施加到金属部件的方法。 在该过程中，使用第一纤维垫和第二纤维垫。
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37.发明申请HIGH-PRESSURE DISCHARGE LAMP COMPRISING A HIGH-VOLTAGE IMPULSE GENERATOR AND METHOD FOR PRODUCING A HIGH-VOLTAGE IMPULSE GENERATOR 审中-公开包含高电压脉冲发生器的高压放电灯和用于生产高压脉冲发生器的方法公开(公告)号：US20100176728A1
公开(公告)日：2010-07-15
申请号：US12663496
申请日：2008-06-02
申请人： Andreas Kloss , Steffen Walter
发明人： Andreas Kloss , Steffen Walter
CPC分类号： H01J61/547 , H01J61/34 , H01J61/82 , H03K3/53 , H05B41/04
摘要： A coating method for coating a spiral pulse generator with a ferritic layer, wherein the spiral pulse generator is surrounded by a ferritic compound that is cured by heat or UV radiation.
摘要翻译： 一种用铁素体层涂覆螺旋脉冲发生器的涂覆方法，其中螺旋脉冲发生器由通过热或UV辐射固化的铁素体化合物包围。
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公开(公告)号：US20090263579A1
公开(公告)日：2009-10-22
申请号：US11992924
申请日：2006-09-26
申请人： Roman Karmazin , Steffen Walter
发明人： Roman Karmazin , Steffen Walter
CPC分类号： C23C10/04 , B22F1/0074 , B22F2998/00 , B22F2998/10 , C22C1/0433 , C23C4/01 , C23C14/042 , C23C16/042 , Y02T50/67 , Y10T428/31678 , B22F2202/03 , B22F2201/04 , B22F3/1021
摘要： Coating processes are often only intended to be applied locally. At the same time, local coating processes cannot always be used, so that frequently masking has to be used. A protective layer contains a binder and titanium oxide and can be used as a diffusion barrier, so that, in a coating process, the coating material is only applied locally. The binder is converted into carbon before the coating.
摘要翻译： 涂覆过程通常仅用于本地应用。 同时，局部涂层工艺不能总是被使用，所以必须经常使用掩模。 保护层含有粘合剂和氧化钛，并且可以用作扩散阻挡层，因此在涂布过程中，涂层材料仅局部施加。 粘合剂在涂层之前转化为碳。
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39.发明申请High-Pressure Discharge Lamp With Improved Ignitability and High-Voltage Pulse Generator 失效高压放电灯具有改进的可燃性和高压脉冲发生器公开(公告)号：US20090261730A1
公开(公告)日：2009-10-22
申请号：US12086879
申请日：2006-12-22
申请人： Andreas Kloss , Ute Liepold , Carsten Schuh , Thorsten Steinkopff , Klaus Stockwald , Steffen Walter
发明人： Andreas Kloss , Ute Liepold , Carsten Schuh , Thorsten Steinkopff , Klaus Stockwald , Steffen Walter
IPC分类号： H01J61/54
CPC分类号： H05B41/042 , H01F27/323 , H01F41/061 , H01J61/34 , H01J61/547 , H01J61/56 , H03K3/537
摘要： High pressure discharge lamp (20) with improved ignitability. A spiral pulse generator (1) that is directly mounted inside the outer piston (12) of the lamp is used for igniting the high pressure discharge lamp.
摘要翻译： 高压放电灯（20）具有改善的点火性能。 直接安装在灯的外活塞（12）内的螺旋脉冲发生器（1）用于点燃高压放电灯。
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公开(公告)号：US20090134796A1
公开(公告)日：2009-05-28
申请号：US12086076
申请日：2006-11-29
CPC分类号： H01J61/366 , H01J5/36
摘要： The invention relates to a metal halide lamp comprising a ceramic discharge vessel (10), characterized in that an MoV leadthrough is connected to a PCA element (Al2O3) by means of a specific adhesive layer containing Al and Mo.
摘要翻译： 本发明涉及一种包括陶瓷放电容器（10）的金属卤化物灯，其特征在于，MoV引线通过含有Al和Mo的特定粘合剂层与PCA元件（Al 2 O 3）连接。
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