公开(公告)号：US08980289B2

公开(公告)日：2015-03-17

申请号：US13819262

申请日：2011-05-26

申请人： Takashi Hara ,  Yuki Higuchi ,  Mikio Fujii

发明人： Takashi Hara ,  Yuki Higuchi ,  Mikio Fujii

IPC分类号： A61K45/00 ,  A61K39/02 ,  A61K39/00 ,  A61K39/38 ,  A61K47/00 ,  A01N63/00 ,  A01N65/00 ,  A23L1/30

CPC分类号： A61K35/747 ,  A23L33/135

摘要： The purpose of the present invention is to provide a better intestine immunomodulator. The intestine immunomodulator of the present invention comprises bacterial cells or a bacterial component of a Lactobacillus paracasei K71 strain having an international deposit No.: FERM BP-11098 as an active ingredient. Preferably, the intestine immunomodulator is used to facilitate production of secretory immunoglobulin A or to activate natural killer cells.

摘要翻译： 本发明的目的是提供一种更好的肠免疫调节剂。 本发明的肠内免疫调节剂包含具有国际保藏号：FERM BP-11098的细菌细胞或副干酪乳杆菌K71菌株的细菌成分作为活性成分。 优选地，肠免疫调节剂用于促进分泌型免疫球蛋白A的产生或激活天然杀伤细胞。

公开(公告)号：US08389194B2

公开(公告)日：2013-03-05

申请号：US12731396

申请日：2010-03-25

申请人： Yoshiaki Akazawa ,  Yoshitaka Kawase ,  Yoritaka Tsubaki ,  Yoshinori Mutoh ,  Keiichi Kikawa ,  Takashi Hara

发明人： Yoshiaki Akazawa ,  Yoshitaka Kawase ,  Yoritaka Tsubaki ,  Yoshinori Mutoh ,  Keiichi Kikawa ,  Takashi Hara

IPC分类号： G03G5/00

CPC分类号： G03G9/0808 ,  G03G9/0815 ,  G03G9/09708 ,  G03G9/09716 ,  G03G9/09725

摘要： A toner manufacturing method, a toner obtained by the method, a one-component developer, a two-component developer, a developing device and an image forming apparatus are provided. By using a toner manufacturing apparatus including a powder passage, a spraying section for spraying a predetermined substance in the powder passage and a rotary stirring section, provided in the powder passage, and stirring particles in the powder passage to apply impact force to the particles so that the particles are fluidized in the powder passage, performed are a stirring step S3 of fluidizing toner core particles with fine inorganic particles adhering to the surfaces thereof and fine resin particles in the powder passage as the powder by the rotary stirring section, and a spraying step S5 of spraying a volatile liquid which softens fine resin particles as a predetermined substance by the spraying section.

摘要翻译： 提供调色剂制造方法，通过该方法获得的调色剂，单组分显影剂，双组分显影剂，显影装置和图像形成装置。 通过使用包括粉末通道的粉末制造装置，用于喷射粉末通道中的预定物质的喷射部分和设置在粉末通道中的旋转搅拌部分，并且搅拌粉末通道中的颗粒以向颗粒施加冲击力 颗粒在粉末通道中流动，是通过旋转搅拌部分将粉末通道中附着有微细无机颗粒的调色剂芯颗粒和作为粉末的粉末通道中的细小树脂颗粒流化的搅拌步骤S3和喷雾 喷洒通过喷涂部软化作为规定物质的树脂微粒的挥发性液体的步骤S5。

公开(公告)号：US08361481B2

公开(公告)日：2013-01-29

申请号：US12989052

申请日：2009-04-24

申请人： Takashi Hara ,  Toshio Joh ,  Takehisa Kumagai ,  Mariko Saito ,  Kimiko Uchiyama

发明人： Takashi Hara ,  Toshio Joh ,  Takehisa Kumagai ,  Mariko Saito ,  Kimiko Uchiyama

IPC分类号： A61K39/02 ,  C12N1/20

CPC分类号： C12R1/225 ,  A23L7/104 ,  A23L33/135 ,  A61K35/74

摘要： An object aims to develop a lactic acid bacterium having an anti-allergic activity, which can be grown by using rice, particularly polished white rice, and can be collected, cooked and ingested together with rice in such a state that the lactic acid bacterium is attached to the surface of the rice. Another object aims to develop a food composition and a pharmaceutical composition, each of which comprises rice containing the lactic acid bacterium as a material. Thus, disclosed are: a lactic acid bacterium Lactobacillus paracasei K71 strain which has been internationally deposited in National Institute of Advanced Industrial Science and Technology, International Patent Organism Depositary under Accession No. FERM BP-11098; an anti-allergic agent comprising the lactic acid bacterium; a food composition comprising the anti-allergic agent; a food composition comprising rice which has been fermented with the lactic acid bacterium, a crushed product of the rice, or a cooked product of the rice or the crushed product of the rice; and a pharmaceutical composition comprising the anti-allergic agent.

摘要翻译： 本发明的目的是开发具有抗过敏活性的乳酸菌，其可以通过使用水稻，特别是抛光的白米来生长，并且可以在乳酸菌为 附着在米的表面。 另一个目的是开发食品组合物和药物组合物，其中每种包含含有乳酸菌作为材料的水稻。 因此，公开了：已经国际保藏在国家先进工业科学技术研究所的国际专利生物保藏中心，保藏号为FERM BP-11098的乳酸菌副干酪乳杆菌K71株; 包含所述乳酸菌的抗过敏剂; 包含抗过敏剂的食品组合物; 包含已经用乳酸菌发酵的米，米粉碎产品或米饭的熟制品或米粉碎产品的食品组合物; 和包含抗过敏剂的药物组合物。

公开(公告)号：US08236474B2

公开(公告)日：2012-08-07

申请号：US12556996

申请日：2009-09-10

申请人： Yoshitaka Kawase ,  Takashi Hara ,  Yoshiaki Akazawa

发明人： Yoshitaka Kawase ,  Takashi Hara ,  Yoshiaki Akazawa

IPC分类号： G03G9/08

CPC分类号： G03G9/09392 ,  G03G9/0808 ,  G03G9/081 ,  G03G9/0825 ,  G03G9/09733

摘要： A method for manufacturing a toner is provided. The method for manufacturing a toner uses a rotary stirring apparatus. The rotary stirring apparatus includes at least a circulation section, a temperature regulation section and a spraying section composed of a two-fluid nozzle. The two-fluid nozzle includes a liquid pipe and an air pipe, the liquid pipe is inserted in the air pipe such that an axis of the liquid pipe coincides with an axis of the air pipe, and at least a part of the liquid pipe and the air pipe is fixed such that the centers of those pipes do not move. A substance in liquid form is sprayed in constant rate from the two-fluid nozzle while regulating temperature and circulating the toner base particles and the fine resin particles in a powder passage, thereby forming a film on the surface of the toner base particle.

摘要翻译： 提供了一种制造调色剂的方法。 调色剂的制造方法使用旋转搅拌装置。 旋转搅拌装置至少包括循环部，温度调节部和由双流体喷嘴构成的喷射部。 双流体喷嘴包括液体管和空气管，液体管插入空气管中，使得液体管的轴线与空气管的轴线重合，并且液体管的至少一部分与 空气管是固定的，使得这些管道的中心不移动。 液体形式的物质在调节温度并使调色剂基础颗粒和细小树脂颗粒循环在粉末通道中时以恒定速率从双流体喷嘴喷射，从而在调色剂基础颗粒的表面上形成膜。

公开(公告)号：US08236473B2

公开(公告)日：2012-08-07

申请号：US12605686

申请日：2009-10-26

申请人： Yoshitaka Kawase ,  Takashi Hara ,  Yoshiaki Akazawa

发明人： Yoshitaka Kawase ,  Takashi Hara ,  Yoshiaki Akazawa

IPC分类号： G03G9/08

CPC分类号： G03G15/08 ,  G03G9/0804 ,  G03G9/0825

摘要： A method for manufacturing a resin-layer coated toner is provided. The method for manufacturing the resin-layer coated toner uses a rotary stirring apparatus including a circulating section, a temperature regulation section, a spraying section and an exhausting section, sprays a liquid substance to particles of toner materials and particles of coating materials in a fluidized state to plasticize such particles from a spraying section by carrier gas and gasifies the liquid, circulates the carrier gas in the powder passage and continuously exhausts the carrier gas including the gasified substance through the exhausting section to the outside of the powder passage, and pressure P1 in the powder passage and pressure P0 outside the powder passage satisfy the following formula (1): 0 atm

摘要翻译： 提供了一种用于制造树脂层涂覆的调色剂的方法。 制造树脂层涂布调色剂的方法使用包括循环部分，温度调节部分，喷射部分和排出部分的旋转搅拌装置，将液体物质喷射到流化床中的调色剂材料颗粒和涂层材料颗粒 状态，通过载气从喷雾部分增塑这样的颗粒，并使液体气化，使载体气体在粉末通道中循环，并将包括气化物质的载气通过排气部分连续排出到粉末通道的外部，并且将压力P1 在粉末通道中，粉末通道外的压力P0满足下列公式（1）：0 atm <（粉末通道中的压力P1 - 粉末通道外的压力P0）＆nlE; 0.3atm（1）。

公开(公告)号：US20110177451A1

公开(公告)日：2011-07-21

申请号：US13009297

申请日：2011-01-19

申请人： Yoritaka TSUBAKI ,  Yoshitaka Kawase ,  Keiichi Kikawa ,  Yoshinori Mutoh ,  Takashi Hara ,  Yoshiaki Akazawa

发明人： Yoritaka TSUBAKI ,  Yoshitaka Kawase ,  Keiichi Kikawa ,  Yoshinori Mutoh ,  Takashi Hara ,  Yoshiaki Akazawa

IPC分类号： G03G9/093

CPC分类号： G03G9/09392 ,  G03G9/09314

摘要： A method for manufacturing a capsule toner, capable of obtaining a capsule toner including a coating layer having uniform thickness at high yield is provided. The method for manufacturing a capsule toner includes a fine resin particle adhering step of adhering fine resin particles to surfaces of toner base particles, a spraying step of spraying a spray liquid for plasticizing the toner base particles and the fine resin particles, while fluidizing the toner base particles and the fine resin particles, and a film-forming step of fluidizing the toner base particles and the fine resin particles until the fine resin particles adhered to the surfaces of the toner base particles are softened to form a film. In the spraying step, ultrasonic vibration is applied to set a number average liquid-droplet diameter of the spray liquid to less than 10 μm.

摘要翻译： 提供了一种制造胶囊调色剂的方法，其能够以高产率获得包含具有均匀厚度的涂层的胶囊调色剂。 制造胶囊调色剂的方法包括：将树脂颗粒粘附到调色剂基础颗粒的表面上的粘附步骤，在调色剂基础颗粒的流化化过程中喷洒用于塑化调色剂基础颗粒和细小树脂颗粒的喷雾液的喷涂步骤 基础颗粒和细树脂颗粒，以及使调色剂基础颗粒和细颗粒树脂颗粒流化直到粘附到调色剂基础颗粒的表面的细小树脂颗粒被软化以形成膜的成膜步骤。 在喷涂步骤中，施加超声波振动以使喷射液体的数量平均液滴直径小于10μm。

公开(公告)号：US20110070541A1

公开(公告)日：2011-03-24

申请号：US12881412

申请日：2010-09-14

申请人： Yoritaka Tsubaki ,  Yoshitaka Kawase ,  Keiichi Kikawa ,  Yoshinori Mutoh ,  Takashi Hara ,  Yoshiaki Akazawa

发明人： Yoritaka Tsubaki ,  Yoshitaka Kawase ,  Keiichi Kikawa ,  Yoshinori Mutoh ,  Takashi Hara ,  Yoshiaki Akazawa

IPC分类号： G03G9/093 ,  G03G9/08

CPC分类号： G03G9/09385 ,  G03G9/09314 ,  G03G9/09378 ,  G03G9/09392

摘要： A capsule toner achieving both low temperature fixability and hot offset resistance, and a method of manufacturing the capsule toner are provided. A capsule toner includes a toner base particle containing a binder resin and a colorant, and a resin coating layer formed on a surface of the toner base particle. The resin coating layer includes a film of plural fine resin particles having different complex viscosities. The plural fine resin particles include first fine resin particles having complex viscosity at a softening temperature of the toner base particles of 5.0×102 Pa·s or more and 1.0×103 Pa·s or less, and second fine resin particles having complex viscosity at a softening temperature of the toner base particles of 1.0×104 Pa·s or more and 1.0×105 Pa·s or less.

摘要翻译： 提供了实现低温定影性和耐热偏移性的胶囊调色剂，以及制造胶囊调色剂的方法。 胶囊调色剂包括含有粘合剂树脂和着色剂的调色剂基础颗粒和形成在调色剂基础颗粒的表面上的树脂涂层。 树脂涂层包括具有不同复合粘度的多种细小树脂颗粒的膜。 多个细小树脂颗粒包括在调色剂基础颗粒的软化温度下的复数粘度为5.0×10 2 Pa·s以上且1.0×10 3 Pa·s以下的第1微细树脂粒子， 调色剂基础颗粒的软化温度为1.0×10 4 Pa·s以上且1.0×10 5 Pa·s以下。

公开(公告)号：US07852647B2

公开(公告)日：2010-12-14

申请号：US12760628

申请日：2010-04-15

申请人： Takayoshi Nishiyama ,  Takashi Hara ,  Koichi Ueki

发明人： Takayoshi Nishiyama ,  Takashi Hara ,  Koichi Ueki

IPC分类号： H02M7/44 ,  G05F1/56

CPC分类号： H02M1/40 ,  H02M3/33515 ,  H02M3/3376 ,  H02M2001/0012

摘要： A switching power supply apparatus includes a transformer or an inductor, a switching element connected to the transformer or the inductor and configured to perform switching of an input power supply, and a switching control circuit including a digital control circuit configured to sample voltage values and/or current values and control on and off of the switching element in accordance with the voltage values and/or current values. The number of points of sampling is set to n or more points, where n is an integer greater than 3, in an ON period of the switching element except at around a turn-on point or a turn-off point of the switching element. The presence or absence of magnetic saturation of the transformer or the inductor is detected on the basis of whether or not a slope of change in current value over time is larger than a predetermined value, and circuit operation is protected from the effect of magnetic saturation. Thus, the presence or absence of magnetic saturation can be rapidly and precisely detected without the influence of switching noise.

摘要翻译： 开关电源装置包括变压器或电感器，连接到变压器或电感器并且被配置为执行输入电源的切换的开关元件以及包括数字控制电路的开关控制电路，该数字控制电路被配置为对电压值和/ 或当前值，并根据电压值和/或电流值控制开关元件的导通和关断。 在开关元件的导通周期内，除了开关元件的导通点或关断点之外，将采样点数设定为n以上，其中n为大于3的整数。 基于电流值随时间变化的斜率是否大于预定值来检测变压器或电感器的磁饱和的存在或不存在，并且保护电路操作免受磁饱和的影响。 因此，不受开关噪声的影响，可以快速，精确地检测磁饱和的存在或不存在。

公开(公告)号：US20100248124A1

公开(公告)日：2010-09-30

申请号：US12731396

申请日：2010-03-25

申请人： Yoshiaki Akazawa ,  Yoshitaka Kawase ,  Yoritaka Tsubaki ,  Yoshinori Mutoh ,  Keiichi Kikawa ,  Takashi Hara

发明人： Yoshiaki Akazawa ,  Yoshitaka Kawase ,  Yoritaka Tsubaki ,  Yoshinori Mutoh ,  Keiichi Kikawa ,  Takashi Hara

IPC分类号： G03G9/00 ,  G03G15/08 ,  G03G9/08 ,  G03G9/093

CPC分类号： G03G9/0808 ,  G03G9/0815 ,  G03G9/09708 ,  G03G9/09716 ,  G03G9/09725

摘要： A toner manufacturing method, a toner obtained by the method, a one-component developer, a two-component developer, a developing device and an image forming apparatus are provided. By using a toner manufacturing apparatus including a powder passage, a spraying section for spraying a predetermined substance in the powder passage and a rotary stirring section, provided in the powder passage, and stirring particles in the powder passage to apply impact force to the particles so that the particles are fluidized in the powder passage, performed are a stirring step S3 of fluidizing toner core particles with fine inorganic particles adhering to the surfaces thereof and fine resin particles in the powder passage as the powder by the rotary stirring section, and a spraying step S5 of spraying a volatile liquid which softens fine resin particles as a predetermined substance by the spraying section.

摘要翻译： 提供调色剂制造方法，通过该方法获得的调色剂，单组分显影剂，双组分显影剂，显影装置和图像形成装置。 通过使用包括粉末通道的粉末制造装置，用于喷射粉末通道中的预定物质的喷射部分和设置在粉末通道中的旋转搅拌部分，并且搅拌粉末通道中的颗粒以向颗粒施加冲击力 颗粒在粉末通道中流动，是通过旋转搅拌部分将粉末通道中附着有微细无机颗粒的调色剂芯颗粒和作为粉末的粉末通道中的细小树脂颗粒流化的搅拌步骤S3和喷雾 喷洒通过喷涂部软化作为规定物质的树脂微粒的挥发性液体的步骤S5。

公开(公告)号：US20100104329A1

公开(公告)日：2010-04-29

申请号：US12451857

申请日：2008-07-08

申请人： Nobuyuki Yoshioka ,  Tadashi Iwamatsu ,  Yoshinori Mutuo ,  Hiroyuki Hirakawa ,  Takashi Hara ,  Takanori Kamoto

发明人： Nobuyuki Yoshioka ,  Tadashi Iwamatsu ,  Yoshinori Mutuo ,  Hiroyuki Hirakawa ,  Takashi Hara ,  Takanori Kamoto

IPC分类号： G03G15/09

CPC分类号： G03G15/09 ,  G03G9/0819 ,  G03G9/107 ,  G03G9/1131 ,  G03G9/1136 ,  G03G9/1139 ,  G03G2215/0607

摘要： Regarding a magnetic carrier of the present invention, a surface of a magnetic core material is coated with a coating layer containing electrically conductive particles and a charge control agent composed of same components as components of a charge control agent contained in a electrophotographic toner. Further, the magnetic carrier exhibits an electric resistance value of 8.22×107 Ωcm to 1.12×1010 Ωcm in an electric field of 4×103 V/cm. This allows the magnetic carrier to stay capable of charging the electrophotographic toner even over a long period of time.

摘要翻译： 对于本发明的磁性载体，磁性材料的表面涂覆有包含导电颗粒的涂层和由与电子照相调色剂中所含的电荷控制剂的组分相同的成分组成的电荷控制剂。 此外，在4×103V / cm的电场中，磁性载体的电阻值为8.22×107＆OHgr·cm〜1.12×1010＆OHgr·cm。 这使得磁性载体即使在长时间内也能够保持对电子照相调色剂的充电。