摘要:
Process for the preparation of antibacterial compounds of the formula ##STR1## comprises condensing an oxo compound of the formula ##STR2## with an amino compound of the formula ##STR3## to produce a compound of the formula ##STR4## reacting the compound of the formula (III) with a compound of the formula ##STR5## to give a compound of the formula ##STR6## and then eliminating the amino-protective group ##STR7##
摘要:
Strains of Actinoplanes produce an antibiotic substance upon aerobic cultivation. The antibiotic is sparingly soluble in water with a pronounced band in the UV absorption spectrum at 307 nm. Methods for preparing and using the antibiotic, both therapeutically and for promoting livestock growth, and composition adapted for these uses are described.
摘要:
Imines of 2-formylquinoxaline-3-carboxylic acid-1,4-dioxides and their salts are obtained through treatment of the lactone or a salt of 2-dihydroxymethylquinoxaline-N,N-dioxide-3-carboxylic acid with a reactant bearing a free primary amino group. Veterinary feedstuffs are produced by combining a nutritious material with an imine as above described.
摘要:
Imines of 2-formylquinoxaline-3-carboxylic acid-1,4-dioxides and their salts are obtained through treatment of the lactone or a salt of 2-dihydroxymethylquinoxaline-N,N-dioxide-3-carboxylic acid with a reactant bearing a free primary amino group. Veterinary feedstuffs are produced by combining a nutritious material with an imine as above described.
摘要:
Imines of 2-formylquinoxaline-3-carboxylic acid-1,4-dioxides and their salts are obtained through treatment of the lactone or a salt of 2-dihydroxymethylquinoxaline-N,N-dioxide-3-carboxylic acid with a reactant bearing a free primary amino group. Veterinary feedstuffs are produced by combining a nutritious material with an imine as above described.
摘要:
Pharmaceutical compositions comprising a 3-amino-1,2,4-benzotriazine-1,4-di-N-oxide as the active ingredient and method of using same. Said compositions exhibit antimicrobial activity and may be used to promote livestock growth by adding an effective amount of said composition to edible fodder.
摘要:
Animal feedstuffs are produced which comprise an antibacterially effective amount of a compound of the formula ##SPC1##WhereinEach of R.sup.1 and R.sup.2, independent of the other, is hydrogen, lower alkyl, hydroxy(lower alkyl), (lower alkoxy)lower alkyl, cyclopentyl, cyclohexyl or cycloheptyl, or R.sup.1 and R.sup.2, together with the nitrogen atom to which they are attached, are pyrrolidino, piperidino, hexamethyleneimino, morpholino or thiomorpholino; and ##EQU1## in which Y is an oxygen or sulfur atom and R.sup.3 is lower alkyl, hydroxy(lower alkoxy), lower alkoxy, pyridyl, or NR.sup.5 R.sup.6 in which each of R.sup.5 and R.sup.6, independent of the other, is hydrogen, lower alkyl, hydroxy(lower alkyl) or lower alkoxy(lower alkyl), or R.sup.5 and R.sup.6, together with the nitrogen atom to which they are attached, are pyrrolidino, piperidino, hexamethyleneimino, morpholino or thiomorpholino;In combination with an animal feed or water. Administration of said compound is useful for accelerating animal growth and improving feed utilization in animals.
摘要:
The invention is related to 7-amino-1-cyclopropyl-6,8-dihalogeno-1,4-dihydro-4-oxo-3-quinoline-carboxylic acids of the formula (I) ##STR1## in which X.sup.1, X.sup.2, R.sup.1 and R.sup.2 have the meaning as pointed out in the following specification. Moreover, the invention is related to a process for the production of the compounds of formula (I) and to antibacterial agents containing them.
摘要:
The invention relates to new quinolone- and naphthyridonecarboxylic acid derivatives which are substituted in the 7-position by a tricyclic amine radical, their salts, processes for their preparation and antibacterial compositions comprising these compounds.
摘要:
Compositions comprising a 3-amino-1,2,4-benzotriazine-1,4-di-N-oxide as the active ingredient exhibit antimicrobial activity and may be used to promote livestock growth by adding an effective amount of said composition to edible fodder.