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公开(公告)号：US20090260986A1
公开(公告)日：2009-10-22
申请号：US12463187
申请日：2009-05-08
IPC分类号： G01N27/26
CPC分类号： G01N27/3272 , Y10S439/909
摘要： A sensor, and methods of making, for determining the concentration of an analyte, such as glucose or lactate, in a biological fluid such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and can include an insertion monitoring trace to determine correct positioning of the sensor in a connector.
摘要翻译： 一种传感器，以及用于使用诸如库仑法，电流分析法和电位法等技术测定生物流体如血液或血清中的分析物如葡萄糖或乳酸盐的浓度的方法。 传感器包括工作电极和对电极，并且可以包括插入监视轨迹，以确定传感器在连接器中的正确定位。
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公开(公告)号：US20090260985A1
公开(公告)日：2009-10-22
申请号：US12437141
申请日：2009-05-07
IPC分类号： G01N27/26
CPC分类号： G01N27/3272 , Y10S439/909
摘要： A sensor, and methods of making, for determining the concentration of an analyte, such as glucose or lactate, in a biological fluid such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and can include an insertion monitoring trace to determine correct positioning of the sensor in a connector.
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公开(公告)号：US20060091006A1
公开(公告)日：2006-05-04
申请号：US11281883
申请日：2005-11-17
申请人： Yi Wang , Joseph Vivolo , Shridhara Alva Karinka
发明人： Yi Wang , Joseph Vivolo , Shridhara Alva Karinka
IPC分类号： G01N33/487
CPC分类号： G01N33/48771 , A61B5/14532 , A61B5/1486 , A61B2562/085 , A61B2562/227 , C12Q1/006
摘要： A sensor, and methods of making, for determining the concentration of an analyte, such as glucose or lactate, in a biological fluid such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and can include an insertion monitoring trace to determine correct positioning of the sensor in a connector.
摘要翻译： 一种传感器，以及用于使用诸如库仑法，电流分析法和电位法等技术测定生物流体如血液或血清中的分析物如葡萄糖或乳酸盐的浓度的方法。 传感器包括工作电极和对电极，并且可以包括插入监视轨迹，以确定传感器在连接器中的正确定位。
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公开(公告)号：US08409425B2
公开(公告)日：2013-04-02
申请号：US13568974
申请日：2012-08-07
摘要： The disclosure provides for reagent compositions for biosensors comprising release polymers, methods of making such biosensors and films of reagent compositions comprising release polymers. The reagent compositions comprise a release polymer and an effective analyte detecting amount of an enzyme an enzyme cofactor and a redox compound capable of acting in a biosensor as (i) a redox mediator associated with a working electrode (ii) a redox couple associated with a reference electrode or (iii) the redox mediator associated with the working electrode and the redox couple for the reference electrode.
摘要翻译： 本公开提供了用于包含释放聚合物的生物传感器的试剂组合物，制备这种生物传感器的方法和包含释放聚合物的试剂组合物的膜。 试剂组合物包含释放聚合物和有效分析物检测量酶，酶辅助因子和能够在生物传感器中起作用的氧化还原化合物作为（i）与工作电极相关联的氧化还原介体（ii）与 参比电极或（iii）与工作电极相关的氧化还原介体和用于参比电极的氧化还原对。
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公开(公告)号：US08163160B2
公开(公告)日：2012-04-24
申请号：US12815169
申请日：2010-06-14
IPC分类号： G01N27/327 , G01N33/50 , G01F1/64
摘要： The present invention provides reagent compositions, and analyte measuring devices and methods that utilize the reagent compositions.
摘要翻译： 本发明提供了试剂组合物以及利用试剂组合物的分析物测量装置和方法。
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公开(公告)号：US20090255811A1
公开(公告)日：2009-10-15
申请号：US12102374
申请日：2008-04-14
摘要： The disclosure provides for reagent compositions for biosensors comprising release polymers, methods of making such biosensors and films of reagent compositions comprising release polymers. The reagent compositions comprise a release polymer and an effective analyte detecting amount of an enzyme an enzyme cofactor and a redox compound capable of acting in a biosensor as (i) a redox mediator associated with a working electrode (ii) a redox couple associated with a reference electrode or (iii) the redox mediator associated with the working electrode and the redox couple for the reference electrode.
摘要翻译： 本公开提供了用于包含释放聚合物的生物传感器的试剂组合物，制备这种生物传感器的方法和包含释放聚合物的试剂组合物的膜。 试剂组合物包含释放聚合物和有效分析物检测量酶，酶辅助因子和能够在生物传感器中起作用的氧化还原化合物作为（i）与工作电极相关联的氧化还原介体（ii）与 参比电极或（iii）与工作电极相关的氧化还原介体和用于参比电极的氧化还原对。
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公开(公告)号：US06939450B2
公开(公告)日：2005-09-06
申请号：US10266548
申请日：2002-10-08
IPC分类号： B01L3/00 , C12Q1/00 , G01N27/403 , G01N33/487 , G01N27/327 , B01L3/02 , G01N21/00
CPC分类号： B01L3/502723 , B01L2300/0645 , B01L2300/0825 , B01L2400/0406 , B01L2400/0688 , C12Q1/001 , G01N27/3272
摘要： A device having a flow channel, wherein at least one flow-terminating interface is used to control the flow of liquid in the flow channel. The flow-terminating interface prevents the flow of the liquid beyond the interface. In one aspect, the invention provides a sensor, such as, for example, a biosensor, in the form of a strip, the sensor being suitable for electrochemical or optical measurement. The sensor comprises a base layer and a cover layer, and the base layer is separated from the cover layer by a spacer layer. The base layer, cover layer, and spacer layer define a flow channel into which a liquid sample is drawn therein and flows therethrough by means of capillary attraction. The flow of the sample is terminated by a flow-terminating interface positioned in the flow channel.
摘要翻译： 一种具有流动通道的装置，其中使用至少一个流动终止界面来控制流动通道中的液体的流动。 流动终止界面防止液体流过界面。 在一个方面，本发明提供一种传感器，例如带状的传感器，例如生物传感器，该传感器适用于电化学或光学测量。 传感器包括基底层和覆盖层，并且基底层通过间隔层与覆盖层分离。 基层，覆盖层和间隔层限定了流动通道，液体样品在其中被抽吸到其中并通过毛细管吸引流过其中。 样品的流动由位于流动通道中的流动终止界面终止。
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公开(公告)号：US06801041B2
公开(公告)日：2004-10-05
申请号：US10145837
申请日：2002-05-14
申请人： Shridhara Alva Karinka , Isabella Moser , Gerhard Jobst , Uwe Tietjen , Panagiota S. Petrou , Uwe Herberth , Gerald Urban
发明人： Shridhara Alva Karinka , Isabella Moser , Gerhard Jobst , Uwe Tietjen , Panagiota S. Petrou , Uwe Herberth , Gerald Urban
IPC分类号： G01N2702
摘要： Sensors that are capable measuring the rate of flow of a fluid that passes over the electrodes of the sensor. In these sensors, an electrode, designated the flow rate-determining electrode, is used in conjunction with the conventional electrodes, e.g., the working electrode, the reference electrode, and the counter electrode, to determine the rate of flow of the fluid. In one aspect, this invention provides a sensor for measuring the concentration of an analyte in a sample of fluid when the sample flows continuously over the electrodes of the sensor, especially when the rate of flow of the sample is relatively low. In another aspect, this invention provides a method for measuring the concentration of an analyte in a sample of fluid, wherein the rate of flow of the sample varies during the period of time that the sensor is in place. In a preferred embodiment, the sensor employs four electrodes, namely, a working electrode, a reference electrode, a counter electrode, and a flow rate-determining electrode. Alternatively, a single electrode that performs both the function of the reference electrode and the function of the counter electrode can replace the reference electrode and the counter electrode. In addition, a dummy electrode or a blank electrode can be used to compensate for interference from electrochemically active species. The reagent(s) specific to the analyte of interest is required to be deposited on the working electrode.
摘要翻译： 能够测量通过传感器电极的流体流速的传感器。 在这些传感器中，与常规电极（例如工作电极，参比电极和对电极）结合使用称为流速确定电极的电极，以确定流体的流速。 一方面，本发明提供一种传感器，用于当样品连续地流过传感器的电极时，特别是当样品的流速相对较低时，用于测量流体样品中分析物的浓度。 在另一方面，本发明提供了一种用于测量流体样品中分析物浓度的方法，其中样品的流速在传感器就位的时间段内变化。 在优选实施例中，传感器使用四个电极，即工作电极，参考电极，对电极和流速确定电极。 或者，执行参考电极的功能和对电极的功能的单个电极可以替代参考电极和对电极。 此外，可以使用虚拟电极或空白电极来补偿来自电化学活性物质的干扰。 需要将特定于目标分析物的试剂沉积在工作电极上。
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公开(公告)号：US20110031133A1
公开(公告)日：2011-02-10
申请号：US12815169
申请日：2010-06-14
摘要： The present invention provides reagent compositions, and analyte measuring devices and methods that utilize the reagent compositions.
摘要翻译： 本发明提供了试剂组合物以及利用试剂组合物的分析物测量装置和方法。
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公开(公告)号：US07754093B2
公开(公告)日：2010-07-13
申请号：US11420628
申请日：2006-05-26
摘要： The present invention provides reagent compositions, and analyte measuring devices and methods that utilize the reagent compositions.
摘要翻译： 本发明提供了试剂组合物以及利用试剂组合物的分析物测量装置和方法。
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