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31.
公开(公告)号:US11466323B2
公开(公告)日:2022-10-11
申请号:US16630593
申请日:2018-07-13
申请人: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. , HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD.
发明人: Yuval Dor , Ruth Shemer , Benjamin Glaser , Judith Magenheim
IPC分类号: C12Q1/6876 , C12Q1/6827 , C12Q1/686 , C12Q1/6869
摘要: A digital droplet PCR method of analyzing the methylation status of methylation sites of a double-stranded DNA molecule which comprises at least two methylation sites per single strand of the double-stranded DNA molecule is disclosed.
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公开(公告)号:US11437501B2
公开(公告)日:2022-09-06
申请号:US17045892
申请日:2019-04-07
申请人: YEDA RESEARCH AND DEVELOPMENT CO. LTD. , YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
发明人: Yossef Paltiel , Ron Naaman , Karen Michaeli , Eilam Smolinsky
IPC分类号: G11C16/04 , H01L29/66 , G01N27/414 , G11C11/02 , H01L29/205 , H01L29/778 , H01L43/06 , H01L29/20
摘要: In a technique for inducing local electric field controlled magnetization, despite the absence of magnetic components, there is provided a novel heterostructure, a semiconductor device thereof, or an array of semiconductor devices. The heterostructure includes a semiconductor substrate carrying a plurality of layers forming at least one heterojunction and hosting a two-dimensional electron gas layer when one of the layer of the plurality of layers is bounded to an interacting layer being a chiral or a biological macromolecule assembly.
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公开(公告)号:US20220251126A1
公开(公告)日:2022-08-11
申请号:US17597878
申请日:2020-08-05
发明人: Dan GIBSON , Amrita SARKAR
摘要: The claimed subject matter provides for a method for conjugating an active material to a Pt complex.
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公开(公告)号:US11357884B2
公开(公告)日:2022-06-14
申请号:US15111567
申请日:2015-01-14
申请人: NANYANG TECHNOLOGICAL UNIVERSITY , YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD
发明人: Terry W. J. Steele , Daniel Mandler
摘要: The present invention relates to electrochemically initiated bioadhesive compositions comprising biocompatible polymers containing derivatives of diazonium, arylsulfonium, or diaryliodonium in general, and to their use in tissue fixation, in particular.
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公开(公告)号:US20220119474A1
公开(公告)日:2022-04-21
申请号:US17431867
申请日:2020-02-19
申请人: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. , HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD.
发明人: Rachel BAR-SHAVIT , Chaim GILON , Amnon HOFFMAN
IPC分类号: C07K14/705 , A61P35/00
摘要: The present invention provides peptides derived from the cytoplasmic region of protease-activated receptors 4 (PAR4) as well as analogs and cyclic analogs, such as backbone cyclic analogs, of these peptides. Pharmaceutical compositions comprising said peptides, analog, cyclic analogs and well as conjugates thereof are provides as well. The peptides, analogs and conjugates of the present invention and pharmaceutical composition comprising thereof have several uses including treating cancer and inhibiting interactions between PARs and protein comprising PH-domain.
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公开(公告)号:US11304989B2
公开(公告)日:2022-04-19
申请号:US16753083
申请日:2018-10-02
发明人: Raymond Kaempfer , Gila Arad
IPC分类号: A61K38/08 , A61K31/215 , A61K31/351 , A61K45/06 , A61P31/16
摘要: Disclosed are peptides, compositions, combinations, kits and methods for the treatment of viral pathogen infection. Combinations and kits comprise the disclosed peptides together with an additional antiviral therapeutic agent.
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公开(公告)号:US11297868B2
公开(公告)日:2022-04-12
申请号:US16304697
申请日:2017-05-29
申请人: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center) , Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
发明人: Moshe Shemesh , Ram Reifen
IPC分类号: A23L33/135 , A61K35/742 , A61K35/747 , C12N1/20 , C12P39/00 , C12R1/25 , C12R1/125
摘要: A method of preparing a bacterial composition is disclosed. The method comprises: (a) in vitro co-culturing beneficial bacteria with biofilm-producing bacteria in a growth substrate under conditions that generate a biofilm which comprises the beneficial bacteria and the non-pathogenic bacteria; and (b) isolating the biofilm from the growth substrate.
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公开(公告)号:US11241147B2
公开(公告)日:2022-02-08
申请号:US14891611
申请日:2014-05-16
申请人: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. , Hadasit Medical Research Services and Development Ltd.
发明人: Itai Hayut , Elchanan Fried , Yaakov Nahmias , Tommy Weiss-Sadan , Ariel Shrem
摘要: A guided tracheal intubation system using an autonomous modulated light source, outputting modulated illumination at a constant level, and externally applied to the subject's larynx region. An optical imaging system receives a video stream from within the subject's throat, including modulated illumination from the subject's trachea. A display control system performs signal processing on the modulated content of the images, and outputs frames of those images in which the intensity level of illumination from the trachea can be controlled without any need to change the illumination output from the modulated light source. The light source has no connection with the rest of the system, and need contain no more than a battery, a power supply circuit and a light source. It can therefore be of low cost and can be made disposable, such as in the form of an adhesive patch applied to the subject's neck.
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公开(公告)号:US20220008354A1
公开(公告)日:2022-01-13
申请号:US17289932
申请日:2019-10-31
发明人: Elka TOUITOU , Hiba NATSHEH
IPC分类号: A61K31/05 , A61K9/00 , A61K47/24 , A61K9/48 , A61K31/352
摘要: Essentially water-free liquid composition for oral administration, comprising: from 25% to 75% by weight of one or more cannabinoid (s); and from 25% to 59% by weight one or more phospholipid (s); and optionally one or more antioxidants (s).
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公开(公告)号:US20210379557A1
公开(公告)日:2021-12-09
申请号:US17288460
申请日:2019-10-23
申请人: Yeda Research and Development Co. Ltd. , Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
发明人: Ron NAAMAN , Claudio FONTANESI , Francesco TASSINARI , Suryakant MISHRA , Eyal CAPUA , Yossef PALTIEL , Shira YOCHELIS , Tzuriel METZGER
IPC分类号: B01J19/08 , B01J19/22 , C07C319/28 , C07C319/02
摘要: A system and method for use in synthesis and promoting interactions of chiral molecules. The system can include: a container configured for containing fluid mixture comprising one or more reactant molecules and at least one surface comprising ferromagnetic or paramagnetic material located to be in at least partial contact with reactants in said container. The ferromagnetic of paramagnetic material can be magnetizable with magnetization direction perpendicular to said at least one surface, thereby providing chiral selective synthesis from said one or more reactant molecules. The technique can enable selective interactions of enantiomers of selected handedness of chiral molecules or formation of selected enantiomers from achiral molecule reactants.
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