公开(公告)号：US20020066866A1

公开(公告)日：2002-06-06

申请号：US09996672

申请日：2001-11-30

Applicant: FUJI PHOTO FILM CO., LTD.

Inventor： Nobuhiko Ogura

IPC: G01N021/64

CPC classification number: G01N21/6456 ,  G01N21/6458 ,  G01N2021/6439 ,  G01N2021/6463 ,  G01N2201/1042

Abstract: An image reading apparatus is adapted for irradiating an image carrier including a labeling substance contained in two-dimensionally distributed spots with a stimulating ray and photoelectrically detecting light released from the labeling substance, thereby producing image data, and the image reading apparatus includes at least one stimulating ray source for emitting a stimulating ray, a lens for shaping the stimulating ray emitted from the at least one stimulating ray source into a line beam, a sensor for photoelectrically detecting light released from the labeling substance, and a controller for performing a stimulation and detection step of irradiating the image carrier including the labeling substance contained in the two-dimensionally distributed spots with the line beam of the stimulating ray to stimulate the labeling substance, stopping irradiation with the line beam of the stimulating ray and causing the sensor to photoelectrically detect light released from the labeling substance after the completion of irradiation with the line beam of the stimulating ray. According to the thus constituted image reading apparatus, it is possible to produce low noise image data rapidly and with a simple operation by irradiating an image carrier including two-dimensionally distributed spots of a labeling substance such as a fluorescent substance, a radioactive labeling substance or the like with a stimulating ray to excite the labeling substance and photoelectrically detecting light released from the labeling substance.

Abstract translation: 一种图像读取装置适用于用包含在二维分布斑点中的标记物质的图像载体用刺激光线照射和光电检测从标记物质释放的光，从而产生图像数据，图像读取装置包括至少一个 用于将从至少一个刺激射线源发射的刺激射线成形为线束的透镜，用于光电检测从标记物质释放的光的传感器，以及用于进行刺激的控制器，以及 将包含二维分布斑点中的标记物质的图像载体用刺激射线的线束照射的刺激标记物质的停止检测步骤，停止用刺激射线的线束照射，使传感器进行光电检测 光从标签上释放出来 在用激发光束的线束照射完成后。 根据这样构成的图像读取装置，可以通过照射包含荧光物质，放射性标记物质等标记物质的二维分布的斑点的图像载体，并且通过简单的操作，可以产生低噪声图像数据。 其具有刺激性射线以激发标记物质并光电检测从标记物质释放的光。

公开(公告)号：US5108179A

公开(公告)日：1992-04-28

申请号：US391481

申请日：1989-08-09

Applicant: Stephen A. Myers

Inventor： Stephen A. Myers

IPC: G01N21/64 ,  G01N27/447

CPC classification number: G01N21/6428 ,  G01N21/645 ,  G01N27/44721 ,  G01N2021/6439 ,  G01N2021/6463 ,  G01N21/6402 ,  G01N21/6456 ,  G01N2201/064 ,  G01N2201/1042

Abstract: The use of continuous wave (CW) laser excitation to measure small differences in the fluorescence of bands of fluorophore stained nucleic acid fragments present in gels is described.

Abstract translation: 描述了使用连续波（CW）激光激发来测量存在于凝胶中的荧光团染色的核酸片段的荧光的微小差异。