公开(公告)号：US20200016579A1

公开(公告)日：2020-01-16

申请号：US16335723

申请日：2017-09-14

Applicant: BASF SE

Inventor： Michael SCHREIBER ,  Zeljko KOTANJAC ,  Michael NILLES ,  Irene de WISPELAERE ,  Michael SCHWARZ ,  Rolf PINKOS ,  Marie Katrin SCHROETER

IPC: B01J25/02 ,  B01J8/02 ,  C07C29/141 ,  C07C29/17 ,  C07C31/12 ,  C07C31/20 ,  B01J35/00 ,  B01J35/04 ,  B01J35/10 ,  B01J37/02 ,  B01J37/06 ,  B01J37/08

Abstract: A process for activating a fixed catalyst bed is disclosed. The fixed catalyst bed includes monolithic shaped catalyst bodies or include monolithic shaped catalyst bodies including at a first metal selected from Ni, Fe, Co, Cu, Cr, Pt, Ag, Au and Pd, and a second component selected from Al, Zn and Si. The fixed catalyst bed, for activation, is treated with an aqueous base having a strength of not more than 3.5% by weight. The base is selected from alkali metal hydroxides, alkaline earth metal hydroxides and mixtures thereof. The fixed catalyst bed has a temperature gradient during the activation and the temperature differential between the coldest point in the fixed catalyst bed and the warmest point in the fixed catalyst bed is kept at not more than 50 K.

公开(公告)号：US10532967B2

公开(公告)日：2020-01-14

申请号：US16340838

申请日：2017-10-17

Applicant: JOHNSON MATTHEY DAVY TECHNOLOGIES LIMITED

Inventor： Roger Bence ,  Robert Gallen ,  Robert Wild

IPC: C07C29/149 ,  C07C31/20

Abstract: A process for the production of propylene glycol from a lactate ester is disclosed. The process comprises supplying a feed comprising a C3-6 alkyl lactate ester. The feed is contacted with a stream of hydrogen containing gas and subjected to hydrogenation in the vapour phase in the presence of a catalyst at a temperature of from about 130° C. to about 185° C., a pressure of from about 20 bar to about 60 bar, and a weight hourly space velocity greater than about 0.3 h−1. The catalyst is a reduced copper catalyst selected from copper alumina, optionally comprising manganese, copper chromite, copper zinc oxide and Raney copper.

公开(公告)号：US10464870B2

公开(公告)日：2019-11-05

申请号：US15514980

申请日：2015-09-23

Applicant: Changchun Meihe Science and Technology Development Co., LTD ,  The Coca-Cola Company

Inventor： Jing Liu ,  Hongbin Qi ,  Haiyu Ren ,  Indra Prakash ,  Yu Shi

IPC: C07C29/00 ,  B01J25/02 ,  B01J23/835 ,  B01J23/888 ,  B01J27/19 ,  C07C31/20 ,  B01J37/04 ,  B01J35/00 ,  B01J27/188 ,  C07C29/132 ,  C07C29/60 ,  B01J23/30 ,  B01J37/00

Abstract: Provided is a method for preparing a diol. In the method, a saccharide and hydrogen as raw materials are contacted with a catalyst in water to prepare the diol. The employed catalyst is a composite catalyst comprised of a main catalyst and a cocatalyst, wherein the main catalyst is a water-insoluble acid-resistant alloy; and the cocatalyst is a soluble tungstate and/or soluble tungsten compound. The method uses an acid-resistant, inexpensive and stable alloy needless of a support as a main catalyst, and can guarantee a high yield of the diol in the case where the production cost is relatively low.

公开(公告)号：US10464008B2

公开(公告)日：2019-11-05

申请号：US16333471

申请日：2017-11-16

Applicant: SABIC Global Technologies B.V.

Inventor： Selvakumar Subramanian ,  Dhaneesh Varappurath Sukumaran ,  Satish Angadi

IPC: B01D53/04 ,  B01D53/26 ,  B01D53/68 ,  C07C29/48 ,  C07C31/20

Abstract: A process for purifying a by-product stream comprising primarily CO2 that emanates from a an ethylene glycol plant, where the by-product stream may contain organic chlorides and water. The process employs an adsorbent to remove one or more organic chlorides from the by-product stream to produce pure or substantially pure CO2. To improve the efficiency of the organic chloride adsorbent, prior to the organic chloride adsorption process, a moisture adsorbent may be employed to remove at least some of the water from the by-product stream.

公开(公告)号：US10414708B2

公开(公告)日：2019-09-17

申请号：US16319960

申请日：2017-07-25

Applicant: SHELL OIL COMPANY

Inventor： Smita Edulji ,  Brendan Dermot Murray

IPC: C07C29/60 ,  C07C31/20 ,  B01J23/83

Abstract: Implementations of the disclosed subject matter provide a process for producing ethylene glycol and propylene glycol from a sorbitol feed which may include contacting the sorbitol feed with hydrogen in a reactor in the presence of a solvent and a bi-functional catalyst system. The bi-functional catalyst system may include a first catalyst comprising a copper compound, a zinc compound, and an additional metal compound and a second catalyst comprising sodium carbonate.

公开(公告)号：US20190263742A1

公开(公告)日：2019-08-29

申请号：US16142547

申请日：2018-09-26

Applicant: Esperion Therapeutics, Inc.

Inventor： Jean-Louis H. Dasseux ,  Carmen D. Oniciu

IPC: C07C31/27 ,  A61K31/20 ,  C07C69/757 ,  A61K31/194 ,  A61K31/23 ,  C07C61/12 ,  C07C47/19 ,  C07C69/003 ,  C07C69/017 ,  C07C47/34 ,  C07D261/12 ,  C07C69/675 ,  C07D261/08 ,  C07C33/26 ,  C07F9/24 ,  C07C309/24 ,  C07C309/25 ,  C07F9/12 ,  C07C309/08 ,  C07C59/01 ,  C07C59/105 ,  C07C59/245 ,  C07D213/80 ,  C07C62/06 ,  C07F9/44 ,  C07F9/09 ,  C07F9/117 ,  C07C59/29 ,  C07D405/12 ,  C07C65/17 ,  A61K31/191 ,  C07C59/46 ,  C07C31/24 ,  C07C59/11 ,  C07C31/20 ,  C07C59/48 ,  C07D309/12 ,  C07D309/10 ,  C07C59/54 ,  C07C31/22 ,  C07C59/285 ,  C07C62/02

Abstract: The present invention relates to novel hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination in bile, pancreatitis, pancreatitius, Parkinson's disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, metabolic syndrome disorders (e.g., Syndrome X), thrombotic disorder. Compounds and methods of the invention can also be used to modulate C reactive protein or enhance bile production in a patient. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.

公开(公告)号：US20190263739A1

公开(公告)日：2019-08-29

申请号：US16340838

申请日：2017-10-17

Applicant: JOHNSON MATTHEY DAVY TECHNOLOGIES LIMITED

Inventor： Roger BENCE ,  Robert GALLEN ,  Robert WILD

IPC: C07C29/149 ,  C07C31/20

Abstract: A process for the production of propylene glycol from a lactate ester is disclosed. The process comprises supplying a feed comprising a C3-6 alkyl lactate ester. The feed is contacted with a stream of hydrogen containing gas and subjected to hydrogenation in the vapour phase in the presence of a catalyst at a temperature of from about 130° C. to about 185° C., a pressure of from about 20 bar to about 60 bar, and a weight hourly space velocity greater than about 0.3 h−1. The catalyst is a reduced copper catalyst selected from copper alumina, optionally comprising manganese, copper chromite, copper zinc oxide and Raney copper.

公开(公告)号：US20190241491A1

公开(公告)日：2019-08-08

申请号：US16262898

申请日：2019-01-30

Applicant: Inolex Investment Corporation

Inventor： Rocco V. Burgo ,  Michael E. Wright ,  Gary B. Mosser ,  Michael J. Fevola

IPC: C07C29/04 ,  C07C31/20 ,  C07C29/80 ,  B01J23/06 ,  B01J37/08 ,  B01J21/04

CPC classification number: C07C29/04 ,  A61L2/18 ,  B01J21/04 ,  B01J23/06 ,  B01J37/08 ,  B01J2523/27 ,  B01J2523/31 ,  C07B41/02 ,  C07B63/00 ,  C07C29/80 ,  C07C31/20

Abstract: A process is incorporated herein for the synthesis of bio-1,2-alkanediols, comprising: providing a bio-alkene having a carbon chain of about 5 to about 20 carbon atoms and a bio-1-alkene regioselectivity of at least about 80%, at least about 92% and/or at least about 95%; and converting the bio-alkene to a bio-1,2-alkanediol having a carbon chain length of about 5 to about 20 carbon atoms. Methods for treating catalysts which may be incorporated in the process for the synthesis of bio-1,2-alkanediols are also included herein. Such bio-1,2-alkanediols are used in compositions and products alone as antimicrobial materials, or with existing bio-compounds and/or antimicrobials, preservatives, alternative preservation systems and/or hurdle technology components. The bio-1,2-alkanediols incorporate a natural and bio-based pathway for antimicrobial effects in various compositions such as cosmetic, pharmaceutical, industrial and household products.

公开(公告)号：US10315973B2

公开(公告)日：2019-06-11

申请号：US15763296

申请日：2015-12-08

Applicant: Dalian Institute of Chemical Physics, Chinese Academy of Sciences

Inventor： Youming Ni ,  Wenliang Zhu ,  Yong Liu ,  Hongchao Liu ,  Lei Shi ,  Zhongmin Liu

IPC: C07C29/10 ,  C07C31/20 ,  B01J29/70 ,  B01J39/05 ,  B01J29/08 ,  B01J29/18 ,  B01J29/40 ,  B01J29/65 ,  B01J31/02

Abstract: This invention provides a method for preparing ethylene glycol by hydrolyzing ethylene glycol monomethyl ether. The method comprises passing a fresh raw material containing ethylene glycol monomethyl ether and water through a reaction zone loaded with a solid acid catalyst to react under the following conditions; separating the reacted mixture via a separation system to obtain a target product of ethylene glycol, by-products containing methanol, dimethyl ether and ethylene glycol-based derivatives, and an unreacted raw material containing ethylene glycol monomethyl ether and water; passing the target product of ethylene glycol into a product collection system; and passing methyl alcohol and dimethyl ether in the by-products into a by-product collection system; and after being mixed with the fresh raw materials containing ethylene glycol monomethyl ether and water, the ethylene glycol-based derivatives in the by-products and the unreacted raw material containing ethylene glycol monomethyl ether and water being recycled into the reaction zone, to realize the preparation of ethylene glycol by hydrolyzing ethylene glycol monomethyl ether. This invention provides a new process to realize the preparation of ethylene glycol by hydrolyzing ethylene glycol monomethyl ether. And in the method, the catalyst has long life and good stability.

公开(公告)号：US10252182B2

公开(公告)日：2019-04-09

申请号：US15494985

申请日：2017-04-24

Applicant: Cameron Solutions, Inc.

Inventor： Joseph Min-Hsiun Lee ,  Gary W. Sams

IPC: B01D1/30 ,  C07C29/76 ,  C07C29/80 ,  C07C31/20

Abstract: Systems and methods for removing solids from a process stream being fed into a flash separator include a solids fluidization device and a solids removal device. The solids fluidization device at the bottom end of the fluid column of the flash separator introduces a swirling motive fluid within the fluid column, while the solids removal device located above the solids fluidization device removes the slurry created by the swirling motive fluid. Systems and methods for fluidizing solids in the fluid column of a flash separator include a solids fluidization device that introduces a swirling motive fluid within the fluid column, means to limit the upward movement of the swirling motive fluid, such as a valve, and removing the solid slurry produced by the swirling motive fluid.