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公开(公告)号:US20210401806A1
公开(公告)日:2021-12-30
申请号:US17363193
申请日:2021-06-30
申请人: Vireo Systems, Inc.
发明人: Mark C. Faulkner , Deeannah Seymour
IPC分类号: A61K31/4168 , A61P31/04 , A61K33/22 , A61K31/194 , A61K9/02 , A61K9/00 , A61K35/747 , A61K31/702 , A61K31/733 , A61K31/7016
摘要: The present invention generally relates to compositions and methods for treatment and prevention of vaginal infections. More particularly, the present invention relates to compositions including creatinine, such as protonated creatinine or creatinine salts, and optionally one or more weak acids, such as boric acid. The disclosed compositions may be used to treat and/or prevent a vaginal infection, such as bacterial vaginosis, to prevent recurrence of a vaginal infection, to treat and/or prevent a sexually transmitted disease (STD) or sexually transmitted infection (STI), and reduce the incidence and/or risk of a subject transmitting a STI or STD.
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公开(公告)号:US20210369765A1
公开(公告)日:2021-12-02
申请号:US16767928
申请日:2018-11-20
发明人: Kyoung Heon KIM , Jungwoo YANG , Ju Hwan SONG , Sora YU
IPC分类号: A61K31/729 , A61Q17/00 , A61K8/73 , A61K8/60 , A61K31/7016 , A61K31/702 , A61P31/04 , A23L33/125 , A23L33/10 , A23K20/163 , A23K20/195
摘要: The present invention relates to a use of agar-derived oligosaccharides for inhibiting the growth of Staphylococcus. More specifically, the present invention provides, as a material for medicine, food, cosmetics and the like, a use of agar-derived agarooligosaccharides, agarobiose or AHG, which have an effect of inhibiting the growth of Staphylococcus or killing the same.
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公开(公告)号:US20210330729A1
公开(公告)日:2021-10-28
申请号:US17313964
申请日:2021-05-06
IPC分类号: A61K36/68 , A61K31/732 , A61K31/7016 , A61K31/733 , A61K31/716 , A61K31/718 , A23L33/125 , A23L33/22 , A23L33/00 , A23L2/52
摘要: The present disclosure relates to compositions comprising dietary fibers. For example, in some embodiments, the composition comprises two or more fibers (e.g., fibers such as wheat dextrin, inulin, pectin, or potato starch) each present in amount of about 2% to about 6% w/w of the composition. The present disclosure also relates to partially hydrolyzed dietary fibers and methods to prepare a partially hydrolyzed dietary. In some embodiments, the composition comprises further comprises an acid and/or a preservative present in an amount of about 0.01% to about 2% w/w of the composition. In some embodiments, the composition further includes a sweetener and/or a flavoring agent. Such compositions are useful in the treatment or improvement of gastrointestinal diseases.
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公开(公告)号:US20210330688A1
公开(公告)日:2021-10-28
申请号:US17367115
申请日:2021-07-02
发明人: Georgios TZORTZIS , Jelena VULEVIC
IPC分类号: A61K31/702 , A61K31/7016 , A61P31/06
摘要: The present invention relates to the use of a galactooligosaccharide composition for preventing or reducing the risk of developing metabolic syndrome.
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公开(公告)号:US11123351B2
公开(公告)日:2021-09-21
申请号:US16797426
申请日:2020-02-21
IPC分类号: A61K31/568 , A61P1/16 , A61K9/48 , A61K47/14 , A61K31/7016 , A61K31/437
摘要: The present invention is directed to a novel pharmaceutical formulation comprising 3α-ethynyl-3β-hydroxyandrostan-17-one oxime in an amount of 0.1-10% by weight of the total weight of the composition; and a vehicle comprising (a) 45-100% of a monoester; (b) optionally up to 51% of a diester; and (c) optionally up to about 10% of a triester. Also claimed is a method for the treatment of medical conditions such as hypersomnia and hepatic encephalopathy by the use of a pharmaceutical formulation as claimed.
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公开(公告)号:US20210275507A1
公开(公告)日:2021-09-09
申请号:US17213678
申请日:2021-03-26
发明人: William Forbes
IPC分类号: A61K31/437 , A61K31/08 , A61K31/352 , A61K31/395 , A61K31/4164 , A61K31/426 , A61K31/4439 , A61K31/606 , A61K31/7016 , A61K31/785 , A61K38/14 , A61K38/31 , A61K45/06
摘要: The application describes treatment of hepatic encephalopathy using gastrointestinal specific antibiotics. One example of a gastrointestinal specific antibiotic is rifaximin.
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公开(公告)号:US20210252031A1
公开(公告)日:2021-08-19
申请号:US17306614
申请日:2021-05-03
申请人: Curemark, LLC
IPC分类号: A61K31/7016 , A61K31/045 , A61K31/7012 , A61K31/047
摘要: A treatment for autism in which an effective amount of lactulose is administered in order to bind excess ammonia in the gastrointestinal tract, the bloodstream, and the nervous system in order to prevent or reverse ammonia poisoning caused by the administration of certain antibiotics. Lactulose molecules in the colon are fermented by certain bacteria. The fermentation process lowers the colonic pH, and ammonia, in the form of ammonium ions, is used by the bacteria for amino acid and protein synthesis. This lowers the serum ammonia levels and reduces neurotoxicity.
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公开(公告)号:US20210252030A1
公开(公告)日:2021-08-19
申请号:US17251429
申请日:2018-10-16
申请人: P. SIVARAJAKUMAR
发明人: P. SIVARAJAKUMAR
摘要: The present invention discloses oral pharmaceutical compositions of Lactulose particularly useful to treat Constipation and hepatic encephalopathy. In particular, the present invention provides consumable, novel gummy delivery systems comprises Lactulose and methods of making the same. The composition comprises Lactulose, gelling agent, sweetener, buffering agents, flavouring agent, colouring agent, anti-tacking agent and preservative. Such gummy compositions for Lactulose may provide improved patient compliance relative to non-gummy compositions. Further the composition comprises Vitamin, nutritional supplements, minerals, antioxidants, soluble and insoluble fibre, herbs, plants, Probiotics, Pre-biotics amino acids, and digestive enzymes.
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公开(公告)号:US11040049B2
公开(公告)日:2021-06-22
申请号:US15903959
申请日:2018-02-23
申请人: Glycom A/S
IPC分类号: A61K31/702 , A61K31/7016 , A61P1/12
摘要: The application relates to a method for the prophylaxis or treatment of non-infectious diarrhea in a human, the method comprising administering to the human an effective amount of one or more human milk oligosaccharides.
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40.
公开(公告)号:US11040021B2
公开(公告)日:2021-06-22
申请号:US16732861
申请日:2020-01-02
申请人: UCL Business PLC
发明人: Rajiv Jalan , Rajeshwar Prosad Mookerjee , Krista Rombouts , Fausto Andreola , Francesco De Chiara , Karen Louise Thomsen
IPC分类号: A61K31/216 , A61K33/42 , A61K31/192 , A61K31/198 , A61K31/437 , A61K31/7004 , A61K31/7016 , A61K45/06 , A61K9/00
摘要: Disclosed herein are methods of preventing, treating, and delaying the onset or progression of diseases associated with hepatic stellate cells (HSCs), such as non-alcoholic fatty liver disease (NAFLD), fibrosis, and liver cancer, using ammonia-lowering therapies.
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