Biopolymer-Dye Complex and Use as a Bioassay
    402.
    发明申请
    Biopolymer-Dye Complex and Use as a Bioassay 审中-公开
    生物聚合物 - 染料复合物和用作生物测定

    公开(公告)号:US20080044805A1

    公开(公告)日:2008-02-21

    申请号:US11842710

    申请日:2007-08-21

    CPC classification number: G01N33/48714

    Abstract: The present disclosure provides rapid, simple, robust and sensitive label and label-free assays for use in drug discovery, bioagent detection and medical diagnostics as well as means for reading such assays. The assays disclosed in the present disclosure use the formation, disruption and destruction of self-assembling fluorescent dye:biopolymer complexes to indicate the presence or absence of an analyte of interest. Such assays are suitable for high throughput screening and can achieve high sensitivity due to the enhanced fluorescence and changes of absorption spectra of certain dyes, particularly cyanine dyes, when they bind to specific biopolymers.

    Abstract translation: 本公开内容提供用于药物发现,生物代谢检测和医学诊断的快速,简单,稳健且灵敏的标记和无标记测定,以及用于阅读这些测定的手段。 本公开中公开的测定法使用自组装荧光染料:生物聚合物复合物的形成,破坏和破坏,以指示感兴趣的分析物的存在或不存在。 这种测定法适用于高通量筛选,并且由于当某些染料,特别是花青染料结合特定的生物聚合物时,增强的荧光和吸收光谱的变化,可以实现高灵敏度。

    Energy Focus for Distance of Flight Mass Spectometry with Constant Momentum Acceleration and an Ion Mirror
    403.
    发明申请
    Energy Focus for Distance of Flight Mass Spectometry with Constant Momentum Acceleration and an Ion Mirror 有权
    具有恒定动量加速度和离子镜的飞行质谱距离的能量聚焦

    公开(公告)号:US20080017792A1

    公开(公告)日:2008-01-24

    申请号:US11865812

    申请日:2007-10-02

    CPC classification number: H01J49/40

    Abstract: A distance-of-flight mass spectrometer (DOF-MS) imparts constant momentum acceleration to ions in an ion source and uses an ion mirror to enhance energy focusing. Embodiments of DOF-MS with ion mirror are shown. Further, a method of compensating for the dispersion of initial ion position and velocity in the ion source is discussed.

    Abstract translation: 飞行时间质谱仪(DOF-MS)对离子源中的离子施加恒定的动量加速度,并使用离子镜增强能量聚焦。 示出了具有离子镜的DOF-MS的实施例。 此外,讨论了补偿离子源中初始离子位置和速度的分散的方法。

    DETECTOR WITH TUNABLE SPECTRAL RESPONSE
    404.
    发明申请
    DETECTOR WITH TUNABLE SPECTRAL RESPONSE 有权
    具有可调光谱响应的探测器

    公开(公告)号:US20070252134A1

    公开(公告)日:2007-11-01

    申请号:US11695429

    申请日:2007-04-02

    Abstract: A semiconductor detector has a tunable spectral response. These detectors may be used with processing techniques that permit the creation of “synthetic” sensors that have spectral responses that are beyond the spectral responses attainable by the underlying detectors. For example, the processing techniques may permit continuous and independent tuning of both the center wavelength and the spectral resolution of the synthesized spectral response. Other processing techniques can also generate responses that are matched to specific target signatures.

    Abstract translation: 半导体检测器具有可调谐的光谱响应。 这些检测器可以与处理技术一起使用,这些处理技术允许创建具有超过下层检测器可获得的光谱响应的光谱响应的“合成”传感器。 例如,处理技术可以允许中心波长和合成光谱响应的光谱分辨率的连续且独立的调谐。 其他处理技术也可以产生与特定目标签名匹配的响应。

    Intersubband detector with avalanche multiplier region
    405.
    发明授权
    Intersubband detector with avalanche multiplier region 有权
    带雪崩乘法器区域的Intersubband检测器

    公开(公告)号:US07271405B2

    公开(公告)日:2007-09-18

    申请号:US10965702

    申请日:2004-10-13

    CPC classification number: H01L31/1075 B82Y10/00 B82Y20/00 H01L31/0352

    Abstract: A photodetector for use at wavelengths of 2 μm and longer has an intersubband absorption region to provide absorption at wavelengths beyond 2 μm, integrated with an avalanche multiplier region to provide low-noise gain. In one particular design, the intersubband absorption region is a quantum-confined absorption region (e.g., based on quantum wells and/or quantum dots).

    Abstract translation: 用于2μm和更长波长的光电检测器具有带间吸收区域,以在超过2μm的波长处提供吸收,与雪崩倍增器区域集成以提供低噪声增益。 在一个特定设计中,子带间吸收区域是量子限制吸收区域(例如,基于量子阱和/或量子点)。

    DENSELY STACKED AND STRAIN-COMPENSATED QUANTUM DOT ACTIVE REGIONS
    406.
    发明申请
    DENSELY STACKED AND STRAIN-COMPENSATED QUANTUM DOT ACTIVE REGIONS 有权
    密封堆积和应变补偿量子有源区

    公开(公告)号:US20070201522A1

    公开(公告)日:2007-08-30

    申请号:US11462777

    申请日:2006-08-07

    CPC classification number: H01S5/34 B82Y20/00

    Abstract: Embodiments provide a quantum dot active structure and a methodology for its fabrication. The quantum dot active structure includes a substrate, a plurality of alternating regions of a quantum dot active region and a strain-compensation region, and a cap layer. The strain-compensation region is formed to eliminate the compressive strain of an adjacent quantum dot active region, thus allowing quantum dot active regions to be densely-stacked. The densely-stacked quantum dot active region provides increased optical modal gain for semiconductor light emitting devices such as edge emitting lasers, vertical cavity lasers, detectors, micro-cavity emitters, optical amplifiers or modulators.

    Abstract translation: 实施例提供量子点有源结构及其制造方法。 量子点有源结构包括基板,量子点有源区域和应变补偿区域的多个交替区域和盖层。 形成应变补偿区域以消除相邻量子点有源区域的压缩应变,从而允许量子点有源区域被密集堆叠。 密集堆叠的量子点有源区域为诸如边缘发射激光器,垂直腔激光器,检测器,微腔发射器,光放大器或调制器的半导体发光器件提供增加的光学模态增益。

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