-
公开(公告)号：US20250154451A1
公开(公告)日：2025-05-15
申请号：US18838822
申请日：2023-02-22
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventor： Congqiang Zhang , Xixian Chen , Sudha Devi D/O Manbahal Shukal , Nicola Yen Min (Chen Yuanming) Tan , Jian Ting Leonard Ong , Chin Chin Lim
Abstract: The present invention relates to host cells comprising genes of the mevalonate and linalool pathways, methods as well as kits for producing linalool.
-
公开(公告)号：US20250137069A1
公开(公告)日：2025-05-01
申请号：US18989874
申请日：2024-12-20
Applicant: Agency for Science, Technology and Research
Inventor： Bong Hwa GAN , Masafumi INOUE , Veronica DIERMAYR
IPC: C12Q1/6886 , A61K31/519 , A61K31/522
Abstract: The present disclosure provides a multiplexed amplification reaction kit for identifying a subject suffering from a malignancy sensitive to treatment with an inhibitor of the Wnt signaling pathway, a method of identifying a subject suffering from a malignancy, a method of identifying sensitivity to an inhibitor of Wnt signaling in a subject suffering from a malignancy, and a method of treating a subject with a malignancy.
-
公开(公告)号：US20250122964A1
公开(公告)日：2025-04-17
申请号：US18685465
申请日：2022-08-18
Applicant: Agency for Science, Technology and Research
Inventor： Ying Ying Wu , Jia Sheng Zach Lee , Ahmad Amirul Bin Abdul Rahim
IPC: F16L37/38 , F16L37/244
Abstract: A connector system having a pair of connector components capable of being used as a reuseable aseptic connection in bioprocessing and/or cell manufacturing processes. Each connector component includes a connector housing having a mating surface with an opening and a door moveable to close and open the opening, and a connector assembly therein. The connector assembly includes a base member having a fluid port; an engagement piece having a pusher portion; and a valve unit therebetween, the valve unit having a resilient deformable valve member. The pusher portion is moveable to cause the pusher portion to urge open the resilient deformable valve member for enabling the fluid flow. When the pair of connector components are interlocked, the doors open and the connector assemblies move and engage with each other through the openings causing the resilient deformable valve members to open for establishing a fluid connection.
-
公开(公告)号：US12278682B2
公开(公告)日：2025-04-15
申请号：US18284022
申请日：2022-03-28
Applicant: Agency for Science, Technology and Research
Inventor： Yijun Zhou , Yan Wah Michael Chia , Xianming Qing
IPC: H04B7/06 , H04B7/0426
Abstract: A method of spatial modulation using an antenna array including radiating elements having power amplifiers communicatively coupled thereto. An amplitude of an output signal to be formed in space is determined by the antenna array based on an input signal. Output amplitude levels for the radiating elements are determined based on the amplitude of the output signal and a current output amplitude level of the antenna array. The first signal(s) for a first subarray of the antenna array and the second signal(s) for a second subarray of the antenna array are generated based on the input signal. The output amplitude levels are assigned to the power amplifiers of the radiating elements. The first signal(s) are sent to radiating elements of the first subarray and the second signal(s) are sent to radiating elements of the second subarray for transmission therefrom to form a combined signal in space as the output signal.
-
公开(公告)号：US20250098963A1
公开(公告)日：2025-03-27
申请号：US18727127
申请日：2023-01-04
Applicant: Agency for Science, Technology and Research , National University Hospital (Singapore) Pte Ltd
Inventor： Malini OLIVO , Yong Geng GOH , Ghayathri BALASUNDARAM , Mohesh MOOTHANCHERY , Renzhe BI , Ruochong ZHANG
Abstract: “Herein disclosed is an ex vivo method of identifying a state of a tumor margin in a sample. The method comprises operating a system to generate an ultrasound image and a photoacoustic image, wherein the system comprises: a probe configured to deliver a pulsed laser from a laser source to a sample, wherein the laser source is operable to generate the pulsed laser; arrays coupled to the probe, wherein one of the arrays comprises transducing elements arranged thereon which are operable to transmit and collect ultrasound signals, and wherein one of the arrays comprises transducing elements arranged thereon which are operable to collect photoacoustic signals; and a data acquisition module which converts the ultrasound signals and the photoacoustic signals into the ultrasound image and the photoacoustic image, respectively.”
-
Patent Agency Ranking
公开(公告)号：US12258449B2
公开(公告)日：2025-03-25
申请号：US17610738
申请日：2020-05-15
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventor： Fuke Wang , Chaobin He , Fei Wang , Yi Ting Chong
Abstract: Photocurable compositions comprising 20-90% by weight of a polymerizable core resin; 20-90% by weight of a diluent resin miscible with said core resin; and at least about 1% by weight of at least one rheology modifier which is distinct from said diluent resin. Rheology modifiers of the present disclosure include compounds which may form covalent bonds with the core resin or diluent resin and compounds which have a particle size of 1-200 nm. Rheology modifiers which may form covalent bonds have at least one terminal functional group selected from the group consisting of acrylates, methacrylates, epoxides, oxetanes, nitriles, alkenes and alkynes.
-
公开(公告)号：US12227511B2
公开(公告)日：2025-02-18
申请号：US18144641
申请日：2023-05-08
Applicant: Agency for Science, Technology and Research
Inventor： Vikrant Arun Adsool
IPC: C07D491/08 , C07D215/233 , C07D401/12 , C07D451/06 , C07D451/14
Abstract: The present disclosure relates to derivatives of bicyclic compounds and their uses in therapy. In particular, the present disclosure relates to derivatives of bicyclic compounds for use in modulating kinase enzymatic activity and accordingly modulating kinase-dependent diseases and conditions such as cancer and in specific embodiments, hepatocellular carcinoma (HCC). The present disclosure also relates to methods of synthesizing these compounds.
-
公开(公告)号：US12195526B2
公开(公告)日：2025-01-14
申请号：US18172773
申请日：2023-02-22
Applicant: Agency for Science, Technology and Research , Singapore Health Services Pte. Ltd. , National University of Singapore
Inventor： Tr Kanaga Sabapathy , David P. Lane , Le-Ann Hwang , Xin Yu Koh , Liew Oi Wah
Abstract: The invention relates to methods for producing an antibody which is specific for a mutant p53 polypeptide over wildtype p53 polypeptide, comprising using as an immunogen a peptide or polypeptide comprising: (i) an antigen sequence, comprising an amino acid sequence of the mutant p53 polypeptide including the mutation and at least one amino acid immediately adjacent to the mutation, and (ii) a scaffold sequence for providing the antigen sequence in a solvent-accessible configuration. Also provided are antibodies produced by such methods, and uses thereof.
-
439.发明申请公开(公告)号：US20250012763A1
公开(公告)日：2025-01-09
申请号：US18704834
申请日：2022-10-26
Applicant: Agency for Science, Technology and Research
IPC: G01N29/24 , A61B8/10 , G01N29/04 , G01N29/07 , G01N33/483
Abstract: There is provided a system and a method of non-contact measurement of one or more mechanical properties of a material, the system comprising an ultrasonic module comprising an ultrasonic applicator configured to apply ultrasonic pressure on a target region of the material; a detection module comprising an electromagnetic wave emitter and an electromagnetic wave detector, said electromagnetic wave emitter being configured to emit an incident beam of electromagnetic waves towards the target region of the material, and said electromagnetic wave detector being configured to detect an emergent beam of electromagnetic waves reflected from the target region and/or transmitted through the target region; and a processing module configured to determine one or more measures corresponding to the one or more mechanical properties of the material, based on changes in the emergent beam of electromagnetic waves.
-
公开(公告)号：US20250011825A1
公开(公告)日：2025-01-09
申请号：US18711011
申请日：2022-12-20
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventor： Zhiwei Song , Wen Min Lau
Abstract: This technology relates to the production of lactose and human milk oligosaccharides (HMOs) in cells.
-
-
-
-
-
-
-
-
-
Search Results
2235
records
(took 0.033 seconds)
