Abstract:
A core-shell emulsion polymer comprising A) a core composition comprising components (a) and (b): (a) from about 40 to about 95% of styrene, alkyl substituted styrene, or alkyl (meth)acrylate; and (b) from about 5 to about 60% of vinylidene chloride, vinyl chloride, or combinations thereof; and B) a shell composition components (c) and (d): (c) from about 50 to about 85% of (I) Rf1(CH2)m Z-C(O)—C(R1)═CH2 (II) Rf2(CH2CF2)q(CH2CH2)rZ-C(O)—C(R1)═CH2, or (III) Rf3O(CF2CF2)q(CH2CH2)rZ-C(O)—C(R1)═CH2 wherein R1 is hydrogen, Cl, F or CH3; Z is —O—, —NH— or —S—; Rf1 and Rf2 are each a C4 or C6 perfluoroalkyl; and Rf3 is a C2 to C7 perfluoroalkyl optionally interrupted by one to three ether oxygens; and (d) from about 15 to about 50% of styrene, alkyl substituted styrene, or alkyl (meth)acrylate, provided that i) the core composition comprises from about 20 to about 75% of the polymer; ii) when Rf1 or Rf2 has 4 carbons, R1 is CH3; and iii) when Rf3 has 2 or 3 carbons, R1 is CH3.
Abstract:
A composition which provides surface effects to substrates comprising a polymer containing at least one urea linkage prepared by (i) reacting (1) at least one organic diioscyanate, polyisocyanate, or mixture thereof, and (2) at least one fluorochemical compound of Formula I Rf—O(CF2CF2)r(CH2CH2)q(R1)sXH Formula (I) wherein Rf is a linear or branched C1 to C7 perfluoroalkyl optionally interrupted by one to three oxygen atoms, r is 1 to 3, q is 1 to 3, s is 0 or 1, X is O, S, or NR2 wherein R2 is H, or C1 to C6 alkyl, and R1 is a divalent radical selected from —S(CH2)n—, p is 1 to 50, and R3, R4 and R5 are each independently H or C1 to C6 alkyl; (ii) and then reacting with (3) water, a linking agent, or a mixture thereof.
Abstract:
Polypeptides having an amino acid sequence of SEQ ID NO: 2, and having amino acid residues 9 to 27 of SEQ ID NO: 2 are disclosed, which are together named C-terminal polypeptides of CKLF1. Also disclosed is a pharmaceutical composition containing a therapeutically effective amount of the CKLF1 C-terminal polypeptide and pharmaceutically acceptable salts, carrier or excipient. Further disclosed are the polynucleotides encoding the C-terminal polypeptides of CKLF1, and vectors and host cells containing the polynucleotides; the in vitro assays for detecting the expression level of the polypeptide or polynucleotide in a test sample; and the monoclonal or polyclonal antibodies against the polypeptides or active fragments thereof. The polypeptides of the present invention can be pharmaceutically used for treating the HIV infection, allergic disease, allograft rejection, diseases in brain and autoimmune diseases.
Abstract translation:公开了具有SEQ ID NO:2的氨基酸序列并且具有SEQ ID NO:2的氨基酸残基9至27的多肽,它们共同命名为CKLF1的C末端多肽。 还公开了含有治疗有效量的CKLF1 C末端多肽和药学上可接受的盐,载体或赋形剂的药物组合物。 还公开了编码CKLF1的C末端多肽的多核苷酸,以及含有多核苷酸的载体和宿主细胞; 用于检测测试样品中多肽或多核苷酸的表达水平的体外测定; 以及针对多肽或其活性片段的单克隆或多克隆抗体。 本发明的多肽可以用于治疗HIV感染,过敏性疾病,同种异体移植排斥,脑部疾病和自身免疫性疾病。
Abstract:
In a data packet router, a router fabric card for routing data packets is provided. The router fabric card comprises a plurality of ingress/egress ports, the ports connected through a switching facility for switching connection states of the port paths between individual ingress paths and individual egress paths on the fabric card, and a scheduling component for scheduling communication between ports on the fabric card. Data coming into ingress on the card is organized into individual data-packet trains, each individual train comprising data packets and inserted data denoting a starting point and an ending point of a train. The switching facility recognizes the start data and the end data of a train and switches port paths to a next-assigned connection state accordingly.
Abstract:
In a data packet router, a router fabric card for routing data packets is provided. The router fabric card comprises a plurality of ingress/egress ports, the ports connected through a switching facility for switching connection states of the port paths between individual ingress paths and individual egress paths on the fabric card, and a scheduling component for scheduling communication between ports on the fabric card. Data coming into ingress on the card is organized into individual data-packet trains, each individual train comprising data packets and inserted data denoting a starting point and an ending point of a train. The switching facility recognizes the start data and the end data of a train and switches port paths to a next-assigned connection state accordingly.
Abstract:
The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formula I both alone and in combination with one or more additional therapeutic agents. The compounds have the general Formula I: including all prodrugs, pharmaceutically acceptable salts and stereoisomers, R1, R2, R3, R6, R7, m and n are described herein.
Abstract:
A polymer having at least one urea linkage prepared by: (i) reacting (a) at least one diisocyanate, polyisocyanate, or mixture thereof, having isocyanate groups, and (b) at least one fluorinated compound selected from the formula (I): Rf(CH2CF2)p(CH2CH2)q(R1)r—XH Formula (I) wherein p and q are each independently an integer of 1 to 3; r is 0 or 1; X is —O—, —NH— or —S—; R1 is a divalent radical selected from the group consisting of —S(CH2)n—, n is an integer of 2 to 4; s is an integer of 1 to 50; R2, R3, and R4 are each independently hydrogen or an alkyl group containing 1 to 6 carbon atoms; and Rf is a linear or branched chain perfluoroalkyl group having 1 to 6 carbon atoms; and (ii) reacting with (c) water, a linking agent, or a mixture thereof and methods for treating substrates to obtain surface effects is disclosed.
Abstract:
A composition which provides surface effects to substrates comprising a polymer containing at least one urea linkage prepared by (i) reacting (1) at least one organic diioscyanate, polyisocyanate, or mixture thereof, and (2) at least one fluorochemical compound of Formula I Rf—O(CF2CF2)r(CH2CH2)q(R1)sXH Formula (I) wherein Rf is a linear or branched C1 to C7 perfluoroalkyl optionally interrupted by one to three oxygen atoms, r is 1 to 3, q is 1 to 3, s is 0 or 1, X is O, S, or NR2 wherein R2 is H, or C1 to C6 alkyl, and R1 is a divalent radical selected from —S(CH2)n—, p is 1 to 50, and R3, R4 and R5 are each independently H or C1 to C6 alkyl; (ii) and then reacting with (3) water, a linking agent, or a mixture thereof.
Abstract translation:提供对包含含有至少一个脲键的聚合物的基材的表面效果的组合物,其通过以下步骤制备:(i)使(1)至少一种有机二硫氰酸酯,多异氰酸酯或其混合物反应,和(2)至少一种式I的含氟化合物 <?in-line-formula description =“In-line Formulas”end =“lead”?> R&lt; f&gt; -O(CF 2 2 CF 2) (CH 2)q(CH 2)2(CH 2)n(CH 2) XH式(I)<?in-line-formula description =“In-line Formulas”end =“tail”?>其中R≠直链或支链 C 1至C 7全氟烷基,任选被一至三个氧原子间隔,r为1至3,q为1至3,s为0或1,X为O ,S或NR 2其中R 2为H或C 1至C 6烷基,且R 1是选自-S(CH 2)n - ,p是1至50,R 3, R 4,R 4和R 5各自独立地为H o R C 1至C 6烷基; (ii),然后与(3)水,连接剂或其混合物反应。
Abstract:
Tetrasubstituted coronenes are provided. Also provided are electronic devices in which the active layer includes a tetrasubstituted coronene.
Abstract:
Disclosed herein is an organic electronic device comprising a charge transport layer comprising a host charge transport material and a guest charge transport material, wherein the guest material is not homogeneously distributed in the host material and is spatially doped within the host material. The charge transport layer may be either a hole or electron transport layer and is useful in a variety of organic electronic devices.