公开(公告)号：US20170218531A1

公开(公告)日：2017-08-03

申请号：US15484536

申请日：2017-04-11

申请人： THE DOSHISHA

发明人： Masatsugu MORIMITSU

IPC分类号： C25C1/08 ,  C25C7/02

CPC分类号： C25C1/08 ,  C25C1/16 ,  C25C7/02 ,  C25C7/06

摘要： An electrowinning system is provided that is capable of suppressing accumulation of a side reaction product on an anode and a rise of an electrolysis voltage caused thereby, and an electrowinning method is provided using the system. To solve this problem, the electrowinning system of the present invention applies predetermined electrolysis current between an anode and a cathode placed in an electrolyte, thereby depositing a desired metal on the cathode, in which the electrolyte is a sulfuric acid-based or chloride-based solution containing ions of the metal, and the anode has a catalytic layer, containing amorphous iridium oxide or amorphous ruthenium oxide, formed on a conductive substrate.

公开(公告)号：US09555028B2

公开(公告)日：2017-01-31

申请号：US14413455

申请日：2013-04-05

申请人： JAPAN BIO PRODUCTS CO., LTD. ,  THE DOSHISHA

发明人： Taiichi Kaku ,  Yoshiharu Kadota ,  Shumpei Yamaguchi ,  Takahiro Nakamura ,  Masashi Akitsu

IPC分类号： A61K31/50 ,  A61K31/4985 ,  A61K38/05 ,  A61K38/12 ,  A61K9/00 ,  A61K9/08

CPC分类号： A61K31/4985 ,  A61K9/0048 ,  A61K9/08 ,  A61K38/05 ,  A61K38/12

摘要： The present invention relates to a medicament for preventing or treating an ocular disease comprising cyclo-trans-4-L-hydroxyprolyl-L-serine as an active ingredient, a medicament for preventing or treating dry eye comprising the compound as an active ingredient, and, in particular, a medicament for preventing or treating dry eye having an action of enhancing mucin secretion and an action of enhancing repair of ocular tissue damage caused by dry eye.

摘要翻译： 本发明涉及用于预防或治疗眼部疾病的药物，其包含环 - 反式-4-L-脯氨酰-L-丝氨酸作为活性成分，用于预防或治疗含有该化合物作为活性成分的干眼剂的药物，以及 特别是用于预防或治疗具有增强粘蛋白分泌作用的干眼剂和增强由干眼引起的眼组织损伤修复作用的药物。

公开(公告)号：US20160331736A1

公开(公告)日：2016-11-17

申请号：US15034710

申请日：2014-11-13

申请人： THE DOSHISHA

发明人： Noriko KOIZUMI ,  Naoki OKUMURA ,  Shigeru KINOSHITA

IPC分类号： A61K31/4439 ,  A61K31/437 ,  A61K31/4418 ,  A61K31/44 ,  A61K31/167 ,  A61K31/5377

摘要： Provided is an agent for treating or preventing a corneal endothelial disorder wherein cell proliferation is required. More specifically, provided is an agent for treating or preventing a corneal endothelial disorder, wherein cell proliferation is required, said agent comprising a p38MAP kinase inhibitor. In a preferred embodiment, the corneal endothelial disorder is a wound. In a preferred embodiment, the p38MAP kinase inhibitor is soluble in water. The p38MAP kinase inhibitor may comprise 4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazole-5-yl]pyridine (SB203580) or a salt thereof.

摘要翻译： 提供用于治疗或预防需要细胞增殖的角膜内皮细胞病症的药剂。 更具体地，提供了治疗或预防角膜内皮细胞障碍的药剂，其中需要细胞增殖，所述药物包含p38MAP激酶抑制剂。 在优选的实施方案中，角膜内皮细胞病变是伤口。 在优选的实施方案中，p38MAP激酶抑制剂可溶于水。 p38MAP激酶抑制剂可以包含4- [4-（4-氟苯基）-2-（4-甲基亚磺酰基苯基）-1H-咪唑-5-基]吡啶（SB203580）或其盐。

公开(公告)号：US20160168733A1

公开(公告)日：2016-06-16

申请号：US15048019

申请日：2016-02-19

申请人： THE DOSHISHA

发明人： Masatsugu MORIMITSU

IPC分类号： C25B11/04 ,  C25B1/26

CPC分类号： C25B11/0484 ,  C02F1/4674 ,  C02F2001/46142 ,  C02F2001/46147 ,  C02F2103/08 ,  C25B1/26 ,  C25B11/0405 ,  C25C7/02

摘要： Provided is a chlorine evolution method which includes contacting an anode with chloride based aqueous solution and generating chlorine as a main reaction at the anode, in which a main reaction of the anode is chlorine evolution, and the chlorine evolution anode which is low in potential of the anode for chlorine evolution, thereby being able to decrease an electrolytic voltage and lower an electric energy consumption rate. The chlorine evolution anode of the present invention is a chlorine evolution anode in which chlorine evolution from an aqueous solution is a main reaction of the anode and also in which a catalytic layer containing amorphous ruthenium oxide and amorphous tantalum oxide is formed on a conductive substrate.

摘要翻译： 提供了一种氯析出方法，其包括使阳极与氯化物基水溶液接触，并在阳极产生氯作为主反应，其中阳极的主反应是氯析出，并且电位低的氯析阳极 用于产生氯的阳极，从而能够降低电解电压并降低电能消耗率。 本发明的析出阳极是氯离子阳极，其中从水溶液中析出的氯是阳极的主反应，并且其中在导电基材上形成含有无定形氧化钌和非晶形氧化钽的催化剂层。

公开(公告)号：US08931286B2

公开(公告)日：2015-01-13

申请号：US11662252

申请日：2005-04-22

申请人： Yoshiaki Watanabe ,  Shinichi Sakamoto

发明人： Yoshiaki Watanabe ,  Shinichi Sakamoto

IPC分类号： F25B9/00 ,  B01D8/00 ,  F28D15/00 ,  F25B9/14

CPC分类号： F28D15/00 ,  F02G2243/54 ,  F25B9/145 ,  F25B2309/003 ,  F25B2309/1403 ,  F25B2309/1405 ,  F25B2309/1416

摘要： A thermoacoustic device 1 for improving heat exchange efficiency is provided which has a first stack 3a including stack constituent elements 3eL and 3eH laminated together, and a first high-temperature side heat exchanger 4 and a first low-temperature side heat exchanger 5, which are provided at two ends of the first stack 3a, in which a self-excited acoustic wave is generated by a temperature difference between the first high-temperature side heat exchanger 4 and the first low-temperature side heat exchanger 5 and is then converted to thermal energy in a stack 3b provided between a second high-temperature side heat exchanger 6 and a second low-temperature side heat exchanger 7. Between the first high-temperature side heat exchanger 4 and the first low-temperature side heat exchanger 5, and between the second high-temperature side heat exchanger 6 and the second low-temperature side heat exchanger 7, a stack constituent element 3eL having a low thermal conductivity, a stack constituent element 3eH having a high thermal conductivity, and a stack constituent element 3eL having a low thermal conductivity are provided in that order.

摘要翻译： 提供了一种用于提高热交换效率的热声装置1，其具有包括层叠在一起的堆叠构成元素3eL和3eH的第一堆叠3a和第一高温侧热交换器4和第一低温侧热交换器5， 设置在第一堆叠3a的两端，其中通过第一高温侧热交换器4和第一低温侧热交换器5之间的温差产生自激式声波，然后将其转换成热 设置在第二高温侧热交换器6和第二低温侧热交换器7之间的堆3b的能量。在第一高温侧热交换器4和第一低温侧热交换器5之间， 第二高温侧热交换器6和第二低温侧热交换器7，具有低导热性的堆叠构成元件3eL，堆叠成分 具有高导热性的元件3eH和具有低导热性的叠层构成元件3eL以该顺序提供。

公开(公告)号：US20140249180A1

公开(公告)日：2014-09-04

申请号：US14349160

申请日：2012-10-03

申请人： THE DOSHISHA ,  National Center for Geriatrics and Gerontology

发明人： Akihiko Takashima ,  Yoshiyuki Soeda ,  Hiroyuki Nagata ,  Yasuo Ihara ,  Tomohiro Miyasaka ,  Hachiro Sugimoto

IPC分类号： A61K31/137 ,  A61K31/472 ,  A61K31/198

CPC分类号： A61K31/137 ,  A61K31/198 ,  A61K31/472

摘要： A tau aggregation inhibitor reduces tau aggregation in cells. The tau aggregation inhibitor can include a catechol structure-containing compound or a salt thereof, and the catechol structure-containing compound can be one of isoprenaline, dopamine, dobutamine, levodopa, levodopa/carbidopa, trimetoquinol, hexoprenaline, methyldopa, and droxidopa. One example of the catechol structure-containing compound is isoprenaline, which can be d-enantiomer of isoprenaline or d/l-racemic mixture of isoprenaline. Tauopathies to be prevented or treated by the inhibitor include AD, Down's syndrome, Pick's disease, corticobasal degeneration, and progressive supranuclear palsy.

摘要翻译： tau聚集抑制剂减少细胞中的tau聚集。 tau聚集抑制剂可以包括含儿茶酚结构的化合物或其盐，并且含儿茶酚结构的化合物可以是异丙肾上腺素，多巴胺，多巴酚丁胺，左旋多巴，左旋多巴/卡比多巴，三甲基喹诺酮，六苯丙氨酸，甲基多巴和洛奇多巴之一。 含邻苯二酚结构的化合物的一个例子是异丙肾上腺素，其可以是异丙肾上腺素的d-对映体或异丙肾上腺素的d / l-外消旋混合物。 由抑制剂预防或治疗的Tauopathies包括AD，唐氏综合征，皮克氏病，皮质基底膜变性和进行性核上性麻痹。

公开(公告)号：US20140231249A1

公开(公告)日：2014-08-21

申请号：US14344757

申请日：2012-08-31

申请人： Masatsugu Morimitsu

发明人： Masatsugu Morimitsu

IPC分类号： C25B11/04 ,  C25C7/02

CPC分类号： C25B11/0484 ,  C02F1/4674 ,  C02F2001/46142 ,  C02F2001/46147 ,  C02F2103/08 ,  C25B1/26 ,  C25B11/0405 ,  C25C7/02

摘要： Provided is a chlorine evolution anode in which a main reaction of the anode is chlorine evolution, and the chlorine evolution anode which is low in potential of the anode for chlorine evolution, thereby being able to decrease an electrolytic voltage and lower an electric energy consumption rate. The chlorine evolution anode of the present invention is a chlorine evolution anode in which chlorine evolution from an aqueous solution is a main reaction of the anode and also in which a catalytic layer containing amorphous ruthenium oxide and amorphous tantalum oxide is formed on a conductive substrate.

摘要翻译： 提供了一种氯离子阳极，其中阳极的主要反应是氯析出，而氯离子阳极的阳极电位低，从而能够降低电解电压并降低电能消耗率 。 本发明的析出阳极是氯离子阳极，其中从水溶液中析出的氯是阳极的主反应，并且其中在导电基材上形成含有无定形氧化钌和非晶形氧化钽的催化剂层。

公开(公告)号：US08806875B2

公开(公告)日：2014-08-19

申请号：US11662253

申请日：2005-04-22

申请人： Yoshiaki Watanabe ,  Shinichi Sakamoto

发明人： Yoshiaki Watanabe ,  Shinichi Sakamoto

IPC分类号： F25B9/00 ,  F25B9/14

CPC分类号： F25B9/145 ,  F02G2243/52 ,  F02G2243/54 ,  F25B2309/1402 ,  F25B2309/1403 ,  F25B2309/1404 ,  F25B2309/1405 ,  F25B2309/1416

摘要： There is provided a thermoacoustic device 1 which has in a loop tube 2, a first stack 3a between a first high-temperature side heat exchanger 4 and a first low-temperature side heat exchanger 5, and a second stack 3b provided between a second high-temperature side heat exchanger 6 and a second low-temperature side heat exchanger 7, so that heat at the first stack side is prevented from being transported to the second stack side even when a large acoustic wave is generated in the tube. In the device, self-excited standing and traveling waves are generated by heating the first high-temperature side heat exchanger 4, and by the standing and traveling waves, the second low-temperature side heat exchanger 7 is cooled. a piezoelectric film 81 is provided to suppress an acoustic streaming and/or a direct-current type flow of a working fluid.

摘要翻译： 提供了一种热声装置1，其在环管2中，在第一高温侧热交换器4和第一低温侧热交换器5之间的第一堆叠3a和设置在第二高温侧热交换器5之间的第二堆叠3b 温度侧热交换器6和第二低温侧热交换器7，使得即使在管内产生大的声波，也能够防止第一堆叠侧的热被输送到第二堆叠侧。 在该装置中，通过加热第一高温侧热交换器4而产生自激站立和行波，并且通过立起和行波，第二低温侧热交换器7被冷却。 提供压电膜81以抑制工作流体的声流和/或直流型流。

公开(公告)号：US08618019B2

公开(公告)日：2013-12-31

申请号：US12491799

申请日：2009-06-25

申请人： Takeshi Kamizono ,  Gang Xie ,  Minoru Inaba

发明人： Takeshi Kamizono ,  Gang Xie ,  Minoru Inaba

IPC分类号： B01J23/42 ,  B01J21/00 ,  C22B11/00 ,  B22F1/00

CPC分类号： B01J23/58 ,  B01J21/18 ,  B01J37/16 ,  B22F1/0018 ,  B22F9/26 ,  B22F2001/0037 ,  B82Y30/00 ,  H01M4/92 ,  H01M4/926

摘要： A producing method includes a preparing step of preparing a chemical compound having at least one of elements of alkali metals and alkali earth metals along with platinum, and a reducing step of reducing the prepared chemical compound with a reducing agent to form platinum nanoparticles.

摘要翻译： 一种制备方法包括制备具有至少一种碱金属和碱土金属元素与铂的化合物的制备步骤，以及还原步骤，用还原剂还原所制备的化合物以形成铂纳米颗粒。

公开(公告)号：US20130134155A1

公开(公告)日：2013-05-30

申请号：US13686668

申请日：2012-11-27

申请人： MURATA MACHINERY, LTD. ,  THE DOSHISHA

发明人： Shinzo YOSHIKADO ,  Yoshihiro SHOJO ,  Isao FUKUDA

IPC分类号： H05B6/64

CPC分类号： H05B6/6402 ,  H05B6/701 ,  H05B6/74 ,  H05B6/78

摘要： A heating chamber is divided into a plurality of spaces by barrier sections including a conductive material. Phase shifters having different lengths with respect to a direction and including a dielectric body having permittivity higher than air are inserted in positions of a terminal section, in the spaces except for at least one space, to differentiate positions of bottoms of standing microwaves formed in the respective spaces from each other with respect to the direction. In addition, impedance adjusters having different lengths with respect to the direction and including a dielectric body having permittivity higher than air are inserted in positions on an upstream side of a region passed by the object to be heated, in the spaces except for at least one space, to reduce differences in impedance of the spaces from an entrance of the heating chamber to the terminal section including the phase shifters.

摘要翻译： 加热室由包括导电材料的阻挡部分分成多个空间。 相对于方向具有不同长度的相位移器并且包括具有高于空气的介电常数的电介质的介电体被插入在除了至少一个空间之外的空间中的端子部分的位置中，以区分形成在该位置的立式微波的底部的位置 相对于方向彼此相对应的空间。 此外，具有相对于方向具有不同长度的阻抗调节器并且包括具有高于空气的介电常数的电介质的介电体被插入到被待加热物体通过的区域的上游侧的位置中，除了至少一个 空间，以减少空间与加热室的入口到包括移相器的端子部分的阻抗的差异。