公开(公告)号：USD709381S1

公开(公告)日：2014-07-22

申请号：US29458572

申请日：2013-06-20

Applicant: Hisamitsu Pharmaceutical Co., Inc.

Designer： Sayaka Mochizuki ,  Yui Takanishi

公开(公告)号：US20040064084A1

公开(公告)日：2004-04-01

申请号：US10687810

申请日：2003-10-20

Applicant: Hisamitsu Pharmaceutical Co., Inc.

Inventor： Kazutaka Inoue

IPC: A61N001/30

CPC classification number: A61N1/325

Abstract: An iontophoresis system comprises a power supply apparatus having a chargeable battery, a positive output terminal, a negative output terminal and a positive charge terminal, and a preparation having input terminals connected to output terminals of the power supply apparatus. The negative output terminal of the power supply apparatus also serves as a negative charge terminal for charging the battery. During charging, the preparation is removed, and terminals of a charger are connected to terminals of the power supply apparatus, respectively. The power supply apparatus comprises a power supply monitoring portion which gives a warning when a battery voltage becomes a predetermined value or lower and a control portion for controlling a power supply state from the output terminal.

公开(公告)号：US20250090822A1

公开(公告)日：2025-03-20

申请号：US18292103

申请日：2022-08-19

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Tetsuji KUWAHARA ,  Keiichiro TSURUSHIMA ,  Masafumi ONO ,  Masato WAKAMATSU ,  Tetsuro TATEISHI

IPC: A61M37/00 ,  A61K9/00 ,  A61K47/32

Abstract: A microneedle patch according to one example includes a backing, an adhesive layer provided on the main surface of the backing, and a microneedle array at least a part of which is positioned within the adhesive layer, wherein the adhesive layer includes a water-soluble polymer and water, and a loss tangent of the adhesive layer under measurement conditions of an environmental temperature of 25° C. and a frequency of 1 Hz is 0.20 to 0.41.

公开(公告)号：US20240139119A1

公开(公告)日：2024-05-02

申请号：US18278279

申请日：2022-02-18

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Hisakazu KURITA ,  Naoto KAMAKURA ,  Tatsuya SAKAKURA

IPC: A61K9/70 ,  A61K31/196

CPC classification number: A61K9/7053 ,  A61K31/196

Abstract: A diclofenac-containing patch package product, in which a diclofenac-containing patch, including an adhesive layer containing diclofenac sodium as a drug and dimethyl sulfoxide as a solvent, and a backing layer, is sealed in a packaging bag,



the packaging bag being formed of a laminate at least comprising:
an innermost layer composed of at least one selected from the group consisting of polyethylene terephthalate and cycloolefin polymer;
an oxygen barrier layer arranged outside the innermost layer; and
an outer layer arranged outside the oxygen barrier layer.

公开(公告)号：US11872320B2

公开(公告)日：2024-01-16

申请号：US17184797

申请日：2021-02-25

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Hiroyuki Sato ,  Hirochika Takano

IPC: A61K47/12 ,  A61K31/196 ,  A61K9/70 ,  A61K9/00

CPC classification number: A61K9/7053 ,  A61K9/0014 ,  A61K9/7076 ,  A61K31/196 ,  A61K47/12

Abstract: Disclosed is a method for treating osteoarthritis comprising a step of administering a patch to a patient. The patch comprises a backing layer and an adhesive layer laminated on the backing layer, the adhesive layer comprises an adhesive base, diclofenac sodium, dimethyl sulfoxide, and an organic acid, and a content of the organic acid is 6 mass % to 8 mass % with respect to a total mass of the adhesive layer. The patch is applied to an affected part once a day, and a dose of diclofenac sodium per administration is 70 mg to 150 mg.

公开(公告)号：US11813364B2

公开(公告)日：2023-11-14

申请号：US17404571

申请日：2021-08-17

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Atsushi Sonobe ,  Takashi Yasukochi ,  Yasunori Takada

IPC: A61K9/70 ,  A61K31/407 ,  A61K47/14 ,  A61K47/10 ,  A61K47/12

CPC classification number: A61K9/7069 ,  A61K9/7053 ,  A61K31/407 ,  A61K47/10 ,  A61K47/14 ,  A61K9/7061 ,  A61K47/12

Abstract: In a patch comprising a support layer and an adhesive agent layer, the adhesive agent layer comprises free asenapine, a maleic acid alkali salt, and a rubber-based adhesive agent.

公开(公告)号：US20230286724A1

公开(公告)日：2023-09-14

申请号：US18040188

申请日：2021-07-30

Applicant: TOPPAN INC. ,  HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Kazuyoshi OKADA ,  Yoshikazu KUWANO ,  Hiroshi OISHI ,  Tetsuhiro KAWANO

IPC: B65D77/38 ,  B65D65/40 ,  B65D77/12

CPC classification number: B65D77/38 ,  B65D65/40 ,  B65D77/12

Abstract: A packaging bag includes a cutting guide band extending along a transverse direction. The cutting guide band includes, a first guide band having first cut lines that are inclined at a predetermined angle with respect to the transverse direction; a second guide band having second cut lines that are inclined at a predetermined angle in a direction opposite a direction of the first cut lines with respect to the transverse direction; and a third guide band having third cut lines that are inclined at a predetermined angle in the same direction as the direction of the first cut lines with respect to the transverse direction. The cutting guide band has a fourth cut line between the first guide band and the second guide band and/or between the second guide band and the third guide band, the fourth cut line being perforated and extending along the transverse direction.

公开(公告)号：US20230071174A1

公开(公告)日：2023-03-09

申请号：US17796365

申请日：2021-02-09

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Hiroyuki SATO ,  Hiroshi INAKURA

IPC: A61K9/70 ,  A61K31/196

Abstract: The present invention provides a patch for relieving lumbago, the patch comprising a backing and an adhesive layer laminated on the backing, wherein the adhesive layer comprises an adhesive base and 0.70 to 1.50 mg of diclofenac sodium per cm2 of application area, and the patch is used by applying the patch once a day to the chest region, the abdominal region, the dorsal region, the brachial region, or the femoral region of a human.

公开(公告)号：US20230015492A1

公开(公告)日：2023-01-19

申请号：US17779885

申请日：2020-11-20

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Naoyuki UCHIDA ,  Satoshi AMANO

IPC: A61K9/70 ,  A61K31/4045 ,  A61K47/08

Abstract: A method for improving holding power of an adhesive agent layer in a ropinirole-containing patch comprising a backing layer and the adhesive agent layer, wherein the adhesive agent layer contains at least one selected from the group consisting of ropinirole and a pharmaceutically acceptable salt thereof and an adhesive agent, the method comprising: causing the adhesive agent layer to further contain a sodium salt of carbonic acid.

公开(公告)号：US20220117934A1

公开(公告)日：2022-04-21

申请号：US17428699

申请日：2020-01-23

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Takao KUROKAWA ,  Hiroyuki ARAKI ,  Kimiko KOMATANI

IPC: A61K31/381 ,  A61K9/70 ,  A61K47/32 ,  A61K47/06

Abstract: The present invention provides a rotigotine stabilization method for stabilizing rotigotine and/or a pharmaceutically acceptable salt thereof in a rotigotine-containing patch comprising a backing layer and an adhesive agent layer, the adhesive agent layer containing the rotigotine and/or the pharmaceutically acceptable salt thereof and a styrene-based thermoplastic elastomer, the method comprising further incorporating cross-linked polyvinylpyrrolidone in the adhesive agent layer in a content of 3 to 25% by mass in the adhesive agent layer.