公开(公告)号：US20070078327A1

公开(公告)日：2007-04-05

申请号：US11187941

申请日：2005-07-25

申请人： Johann Kindlein

发明人： Johann Kindlein

IPC分类号： A61B5/05

CPC分类号： A61N5/1007 ,  A61B2034/2051 ,  A61N5/103 ,  A61N5/1048 ,  A61N2005/1008 ,  A61N2005/1012 ,  A61N2005/1018 ,  A61N2005/1058

摘要： The invention relates to a method for identifying the location at least one treatment channel from a group of a plurality of treatment channels as wells as a system for effecting radiation treatment on a pre-selected anatomical portion of an animal body. According to the invention the identifying method being characterized by the steps of A selecting at least one of said plurality of treatment channels; B reconstructing the actual location of said selected treatment channel relative to said animal body; and C comparing said reconstructed location said pre-planned plurality of locations. Furthermore the system according to the invention is characterized in that identifying means are present for identifying the location of at least one treatment channel from said group of said plurality of inserted treatment channels and comparing said identified location with one or more of said pre-planned locations present in said treatment plan.

摘要翻译： 本发明涉及一种用于鉴定来自多个治疗通道的组的至少一个治疗通道的位置的方法，作为用于对预先选择的动物体的解剖部分进行辐射治疗的系统。 根据本发明，识别方法的特征在于以下步骤：A选择所述多个治疗通道中的至少一个; B重建所述选择的治疗通道相对于所述动物体的实际位置; 和C比较所述重建位置所述预先计划的多个位置。 此外，根据本发明的系统的特征在于，存在用于识别来自所述多个插入的治疗通道的所述组的至少一个治疗通道的位置的识别装置，并且将所述识别的位置与一个或多个所述预先计划的位置进行比较 出现在治疗计划中。

公开(公告)号：US20060014997A1

公开(公告)日：2006-01-19

申请号：US11167166

申请日：2005-06-28

申请人： Johann Kindlein ,  Frits Van Krieken

发明人： Johann Kindlein ,  Frits Van Krieken

IPC分类号： A61N5/00

CPC分类号： A61N5/1015

摘要： The invention relates to a device for radiation treatment of proliferative tissue surrounding a cavity in an animal body comprising at least an inflatable balloon system having a balloon wall for placement in said cavity; a supportive probe having an elongated body with a distal end connected with said inflatable balloon system and a proximal end remaining outside said cavity; inflation means for inflating and deflating said balloon system with a pressurized medium; radiation delivering means for placing at least one energy emitting source within said cavity for performing said radiation treatment. It is an object of the invention to provide a device for radiation treatment of proliferative tissue surrounding a cavity in an animal patient body according to the above preamble capable in controlling the real, actual status of the inflated balloon system present inside said body cavity, especially when said device is utilized with an after loading apparatus. The device is according to the invention characterized in that said device comprises monitoring means for monitoring the inflation status of the inflatable balloon system. Hence with the device according to the invention the actual inflation status of the inflated balloon system can be determined, providing accurate information about the operational conditions of the device during radiation treatments being performed in an animal body. Any malfunction can be easily detected thereby obviating the risk of any misadministration of a radiation dose to the patient.

摘要翻译： 本发明涉及一种用于放射治疗包围动物体腔内的增生组织的装置，该装置包括至少一个具有用于放置在所述空腔中的球囊壁的可膨胀球囊系统; 支撑探针，其具有细长体，其远端与所述可充气球囊系统连接，并且近端保持在所述空腔外; 膨胀装置用于用加压介质对所述球囊系统进行充气和放气; 辐射传送装置，用于将至少一个能量发射源放置在所述空腔内用于进行所述辐射处理。 本发明的一个目的是提供一种用于根据上述前序能够对动物患者体内空腔周围的增生组织进行放射治疗的装置，其能够控制存在于所述体腔内的充气球囊系统的实际状态，特别是 当所述装置与后装载装置一起使用时。 根据本发明的装置，其特征在于，所述装置包括用于监测可充气球囊系统的充气状态的监视装置。 因此，根据本发明的装置，可以确定充气球囊系统的实际充气状态，在动物体内执行放射治疗期间提供关于装置的操作条件的准确信息。 可以容易地检测到任何故障，从而避免了向患者施加辐射剂量的任何错误的风险。

公开(公告)号：US20050101823A1

公开(公告)日：2005-05-12

申请号：US10669359

申请日：2003-09-25

申请人： Luis Linares ,  Johann Kindlein

发明人： Luis Linares ,  Johann Kindlein

IPC分类号： A61N5/10 ,  A61M36/04

CPC分类号： A61N5/1015 ,  A61N2005/1018

摘要： The invention relates to a device for radiation treatment of proliferative tissue surrounding a cavity in an animal body comprising: at least a first inflatable chamber having a wall for placement in said cavity; a supportive probe having an elongated body with a distal end connected with said at least first inflatable chamber and a proximal end remaining outside said cavity; inflation means for inflating and deflating said at least first chamber; radiation delivering means for placing at least one energy emitting source within said cavity for performing said radiation treatment. The invention aims to provide a device according the above preamble, wherein it is possible to temporarily position a solid energy emitting source in a reproducible manner at different locations within the inflated chamber, such that subsequent identical radiation treatment sessions can be performed, whereas the comfort of the patient is maxim and an out hospitalization treatment is possible. According to the invention said radiation delivering means comprises at least one hollow, flexible tunnel channel having at least one fixation point to said wall of said first inflatable chamber and a proximal end remaining outside said cavity; wherein said at least one hollow, flexible tunnel channel serves to guide said at least one radiation emitting source inside said cavity.

摘要翻译： 本发明涉及一种用于放射治疗包围动物体腔内的增生组织的装置，包括：至少第一充气室，其具有用于放置在所述空腔中的壁; 支撑探针，其具有细长体，远端与所述至少第一可充气室连接，远端保持在所述空腔外; 膨胀装置用于使所述至少第一室充气和放气; 辐射传送装置，用于将至少一个能量发射源放置在所述空腔内用于进行所述辐射处理。 本发明旨在提供一种根据上述前序部分的装置，其中可以将可再生能量的固体能量发射源临时定位在充气室内的不同位置，使得可以执行后续相同的辐射治疗会话，而舒适度 的患者是最大的，可以进行住院治疗。 根据本发明，所述辐射递送装置包括至少一个中空的柔性隧道通道，其具有至少一个固定点到所述第一可充气室的所述壁，以及保持在所述空腔外部的近端; 其中所述至少一个中空柔性隧道通道用于在所述空腔内引导所述至少一个辐射发射源。

公开(公告)号：US20050031083A1

公开(公告)日：2005-02-10

申请号：US10878160

申请日：2004-06-29

申请人： Johann Kindlein

发明人： Johann Kindlein

IPC分类号： A61N5/10 ,  H01J35/06 ,  H01J35/16 ,  H01J35/20 ,  H01J35/32 ,  H01J29/50

CPC分类号： A61N5/1001 ,  H01J35/20 ,  H01J35/32 ,  H01J2235/205

摘要： The invention relates to a miniature X-ray source device connected to a distal end of a guiding wire for insertion towards a desired location within an animal body for effecting radiation therapy, said X-ray source device at least comprising a vacuum tube containing a cathode and an anode spaced apart at some distance from each other; emitting means for emitting free electrons from the cathode; electric field generating means for applying during use a high-voltage electric field between said cathode and said anode for accelerating said emitted free electrons towards said anode; a getter material located in a high-voltage electric field free region in said vacuum tube; wherein said vacuum tube being at least partly transparent to X-ray radiation emitted by said anode. It is necessary to locate the getter material inside the vacuum tube at a location, where no electric field between the anode and cathode exits. An essentially electric field free location of the getter material is required as therefore the getter would not present any internal electrical problems associated with surface arcing or breakdown. To this end, in order to benefit from the use of a getter material inside the vacuum tube for improving the vacuum level inside as well as avoiding any electrical problems as mentioned above and to obtain an improved miniature X-ray tube source device having reduced constructional dimensions according to the invention said cathode is arranged for shielding said getter material from said high-voltage electric field.

摘要翻译： 本发明涉及连接到导丝线的远端的微型X射线源装置，用于插入到动物体内的所需位置以进行放射治疗，所述X射线源装置至少包括含有阴极的真空管 以及在彼此间隔一定距离的阳极; 用于从阴极发射自由电子的发射装置; 电场产生装置，用于在使用期间施加所述阴极和所述阳极之间的高压电场，用于将所述发射的自由电子加速到所述阳极; 位于所述真空管中的高压无电场区域中的吸气剂材料; 其中所述真空管对于由所述阳极发射的X射线辐射至少部分透明。 必须将吸气剂材料定位在真空管内的阳极和阴极之间没有电场的位置。 因此，吸气剂材料基本上无电场的位置是必需的，因此吸气剂不会呈现与表面起弧或击穿相关的任何内部电气问题。 为此，为了在真空管内部使用吸气材料以改善内部的真空度以及避免如上所述的任何电气问题，并且获得具有减小的结构的改进的微型X射线管源装置 根据本发明的尺寸，所述阴极被布置用于从所述高压电场屏蔽所述吸气材料。