公开(公告)号：US20210238151A1

公开(公告)日：2021-08-05

申请号：US17145357

申请日：2021-01-10

Applicant: KUWAIT UNIVERSITY

Inventor： CHARLES IFEAMALUME EZEAMUZIE ,  OLUDOTUN ADEBAYO PHILLIPS

IPC: C07D263/06 ,  A61P37/08 ,  A61P11/06

Abstract: Oxazolidione hydroxamic acid derivatives of the general formula (I): where R1 is hydrogen or hexanoyl and R2 is amino, methyl, ethyl, propyl, isopropyl, cyclopropyl, butyl, isobutyl, cyclobutyl, pentyl, cyclopentyl, hexyl or heptyl, and pharmaceutically acceptable salts thereof, act as dual inhibitors of 5-lipoxygenase and mast cell degranulation. The oxazolidinone hydroxamic acid derivatives or pharmaceutically acceptable salts thereof can be used in the prevention and treatment of asthma and allergies, as well as inflammatory conditions.

公开(公告)号：US20200330934A1

公开(公告)日：2020-10-22

申请号：US16386219

申请日：2019-04-16

Applicant: KUWAIT UNIVERSITY

Inventor： BADER SHAFAQA AL-ANZI

IPC: B01F5/02 ,  B01F3/04

Abstract: The confined plunging liquid jet reactor with modified downcomer includes a downcomer having an upper end, an open lower end, and a gas inlet for receiving gas. A plurality of longitudinally-extending baffles and/or a sieve are mounted in the downcomer, adjacent the open lower end thereof. A nozzle is mounted on the upper end of the downcomer for receiving a pressurized liquid from an external source to generate a liquid jet. The liquid jet impinges on liquid contained within the downcomer creating turbulence and bubbles with the gas entrained therein. The open lower end of the downcomer is positioned within a receiving tank holding a reservoir of the liquid such that a portion of the mixture of the liquid and the gas exits the open lower end of the downcomer to flow into the receiving tank.

公开(公告)号：US20190124883A1

公开(公告)日：2019-05-02

申请号：US15801157

申请日：2017-11-01

Applicant: KUWAIT UNIVERSITY

Inventor： HAMEED ALI AL-SARRAF

IPC: A01K1/035 ,  A01K15/02

CPC classification number: A01K1/035 ,  A01K1/031 ,  A01K1/0613 ,  A01K15/027

Abstract: A system for examining resistance exercise includes a first trap compartment, a second trap compartment, a main track compartment and a pulley system which can be aligned to form a continuous tunnel. Each of the compartments can have adjustable dimensions to retain small animals of various sizes. The pulley system includes a clamp and a pulley shaft. The pulley shaft is pivotally attached to the clamp at a lower end and a first pulley wheel at an upper end. A second pulley wheel is pivotally attached to the clamp. A rope is trained on the pulley wheels. The tunnel can be positioned on an elevated support surface. One end of the rope is attachable to a rat on the elevated support surface and the other end of the rope is to attached to liftable strength training objects positioned below the elevated support surface.

公开(公告)号：US20190103150A1

公开(公告)日：2019-04-04

申请号：US15724075

申请日：2017-10-03

Applicant: KUWAIT UNIVERSITY

Inventor： IMTIAZ AHMAD ,  MAHMOUD IMDOUKH ,  MOHAMMAD GH. ALFAILAKAWI

IPC: G11C11/16 ,  G11C11/56

CPC classification number: G11C11/1675 ,  G11C7/1006 ,  G11C11/1653 ,  G11C11/5607

Abstract: Data is stored in a multi-level MRAM (MLC MRAM) cell in a manner that reduces transition states that require high energy. A new data block is received, and the new data block is divided into one or more sub-groups of bits, with each sub-group comprising at least two bits. Each sub-group is assigned data bit locations in a memory store. The received bits are compared with sub-groups present at the data bit locations to determine subgroups of hot bits. For each subgroup of hot bits, an encoding flag value is determined by XORing their most significant bits. The most significant bits of each subgroup of hot bits are complemented and the encoding flag is SET. A data block is generated to establish a data group for each subgroup of hot bits including the subgroup of hot bits and the encoding flag for that subgroup.

公开(公告)号：US10206896B2

公开(公告)日：2019-02-19

申请号：US16020517

申请日：2018-06-27

Applicant: KUWAIT UNIVERSITY

Inventor： Milad S. Bitar ,  Fahd Al-Mulla

IPC: C07H21/02 ,  C07H21/04 ,  A61K31/70 ,  A61K31/19 ,  C12N15/113 ,  A61K31/56 ,  C12N5/00

Abstract: The method of treating delayed healing of a wound associated with diabetes includes administering to the wound a composition comprising an anti-senescence compound and a pharmaceutically acceptable carrier. The anti-senescence compound may be 18α-Glycyrrhetinic acid, a Caveolin-1 (Cav-1) inhibitory compound, or a Polymerase I Transcript Release Factor (PTRF-1) inhibitory compound. The anti-senescence compound may be effective in preventing and/or reversing premature cellular senescence. The anti-senescence compound may be effective in promoting healing of a wound, e.g., delayed or incompletely healed wound. The anti-senescence compound may be effective in promoting healing of a delayed healing wound or chronic wound of a diabetic patient, such as a diabetic ulcer or venous ulcer.

公开(公告)号：US10202261B2

公开(公告)日：2019-02-12

申请号：US15490513

申请日：2017-04-18

Applicant: KUWAIT UNIVERSITY

Inventor： Naif B. Almutairi ,  Mohamed Zribi

IPC: G06F7/70 ,  G06F19/00 ,  G06G7/00 ,  G06G7/76 ,  B66C13/18 ,  G05B13/02 ,  B66C19/00

Abstract: The heuristic fuzzy controller for gantry cranes provides for controlling the position of the cart of a gantry crane while suppressing the swing angle of the payload. The rules of the controller are obtained taking into account the knowledge of an experienced crane operator. The controller uses only one fuzzy system to achieve the two control objectives.

公开(公告)号：US10087238B2

公开(公告)日：2018-10-02

申请号：US15439807

申请日：2017-02-22

Applicant: KUWAIT UNIVERSITY

Inventor： Waleed Ebrahim Al-Herz ,  Fawzi Abdalla Babiker

IPC: A61P9/10 ,  A61K39/395 ,  C07K16/00 ,  A61K9/00 ,  C07K16/18

Abstract: The method of preventing reperfusion injury in reperfusion therapy is a medical technique for prevention of reperfusion injury in a patient where reperfusion therapy is necessary, such as following myocardial infarction (MI) or heat transplant in the patient. The patient is treated with intravenous immunoglobulin (IVIG) prior to an ischemic event or, alternatively, following the ischemic event, with the intravenous immunoglobulin providing cardio-protective effects to the patient for preventing reperfusion injury. The treatment with the IVIG may be used with any suitable type of reperfusion therapy, such as thrombolytic therapy, coronary angioplasty or coronary artery bypass surgery.

公开(公告)号：US10045880B2

公开(公告)日：2018-08-14

申请号：US15003739

申请日：2016-01-21

Applicant: KUWAIT UNIVERSITY

Inventor： Bader Shafaqa Al-Anzi

IPC: A61F7/02 ,  A61F7/00 ,  A61B5/01 ,  A61B5/00

Abstract: The cooling system for patients with fever is a mechanical, fluid-based system for cooling patients suffering from fever. The cooling system for patients with fever includes a reservoir for containing a cooling fluid, which is maintained at a desired temperature. A temperature sensor is received in the reservoir. The temperature sensor is immersed in the cooling fluid for measuring the temperature thereof. A chiller is also received in the reservoir for selectively cooling the cooling fluid when the temperature thereof, measured by the temperature sensor, is above a pre-set temperature threshold. The reservoir communicates with a cooling pad, which is formed from a padded layer having at least one channel embedded therein. At least one pump and tubing is provided for circulating the cooling fluid through the reservoir and the cooling pad. In use, the cooling pad is applied to the skin of a patient with a fever.

公开(公告)号：US09904961B2

公开(公告)日：2018-02-27

申请号：US14706940

申请日：2015-05-07

Applicant: KUWAIT UNIVERSITY

Inventor： Ghufran Abdullah Al-Shiridah ,  Khaled Mahdi ,  Maytham Safar

IPC: G06F15/16 ,  G06Q50/00 ,  H04L12/24

CPC classification number: G06Q50/01 ,  H04L41/145 ,  H04L41/16

Abstract: The system and method for determining the feedback capacity of information distributed in a complex network determines feedback capacity as information is received and diffused throughout the network. Traditionally, real networks, such as computer networks, were used in determining network feedback. However, current complex networks typically incorporate graphing models for network analysis. The system and method provide a process to determine the quality of a complex network with respect to feedback capacity, such as can be determined by a corresponding Belief Propagation algorithm and a corresponding entropy equation. The system and method can also determine the cyclic entropy per penetration in a complex network, the depth penetration for nodes in the complex network and a plurality of cycle counts per node in the complex network based on a source node.

公开(公告)号：US20150352064A1

公开(公告)日：2015-12-10

申请号：US14301301

申请日：2014-06-10

Applicant: Kuwait University

Inventor： MILAD S. BITAR ,  FAHD AL-MULLA

IPC: A61K31/19 ,  C12N15/113

CPC classification number: A61K31/19 ,  A61K31/56 ,  C12N15/113 ,  C12N2310/11 ,  C12N2310/14 ,  C12N2310/3233

Abstract: The method of treating delayed healing of a wound associated with diabetes includes administering to the wound a composition comprising an anti-senescence compound and a pharmaceutically acceptable carrier. The anti-senescence compound may be 18α-Glycyrrhetinic acid, a Caveolin-1 (Cav-1) inhibitory compound, or a Polymerase I Transcript Release Factor (PTRF-1) inhibitory compound. The anti-senescence compound may be effective in preventing and/or reversing premature cellular senescence. The anti-senescence compound may be effective in promoting healing of a wound, e.g., delayed or incompletely healed wound. The anti-senescence compound may be effective in promoting healing of a delayed healing wound or chronic wound of a diabetic patient, such as a diabetic ulcer or venous ulcer.

Abstract translation: 治疗与糖尿病相关的伤口的延迟愈合的方法包括向伤口施用包含抗衰老化合物和药学上可接受的载体的组合物。 抗衰老化合物可以是18α-甘草次酸，窖蛋白-1（Cav-1）抑制化合物或聚合酶I转录物释放因子（PTRF-1）抑制化合物。 抗衰老化合物可以有效预防和/或逆转过早的细胞衰老。 抗衰老化合物可有效促进伤口愈合，例如延迟或不完全愈合的伤口。 抗衰老化合物可有效促进糖尿病患者如糖尿病性溃疡或静脉溃疡的延迟愈合伤口或慢性伤口的愈合。