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公开(公告)号：US20220002678A1
公开(公告)日：2022-01-06
申请号：US17294913
申请日：2019-11-19
发明人： Yuzo YOSHIDA , Tsutomu SOMA , Jiro KISHIMOTO , Takashi MATSUZAKI
IPC分类号： C12N5/071 , C12N5/077 , A01K67/027
摘要： The present invention provides: a composition for reconstituting human skin tissue having hair follicles, the composition characterized by containing human epidermal cells and human dermal cells, the human dermal cells containing cell groups of human hair papilla derived from non-embryos via spheroid formation; and a human skin tissue model animal to which said composition is applied. The invention also provides a method for producing said composition and animal.
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公开(公告)号：US11213463B2
公开(公告)日：2022-01-04
申请号：US15206639
申请日：2016-07-11
发明人： Shun Kubota , Hideo Hata , Malyn Concina , Michelle Lou , Hideki Takahashi , Julie Shown , Yosuke Ikebe
摘要： An oil-in-water type emulsified cosmetic and a method of making can be prepared in a system not containing a silicone and is surprisingly produced without a wet-type dispersion apparatus by using a specific combination of the oil component constituting the oily phase and a hydrophobizing agent for a hydrophobized powder. The composition includes an aqueous phase; an oily phase dispersed in the aqueous phase; and a powder dispersed in the oily phase. The oily phase comprises (a) volatile hydrocarbon oil and (b) non-volatile hydrocarbon oil in a combined amount of 40% by mass or more with respect to the total oil content, wherein the blending ratio of (b) non-volatile hydrocarbon oil to (a) volatile hydrocarbon oil, [(b)/(a)], is within a range of 0 to 2.5, and the powder comprises a powder having a surface hydrophobized by a treatment with a metallic soap consisting of a higher fatty acid and a divalent metal or a composite treatment with a higher fatty acid and a divalent metal hydroxide.
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公开(公告)号：US11191703B2
公开(公告)日：2021-12-07
申请号：US16481682
申请日：2018-01-30
发明人： Noriko Tomita
摘要： A non-sticky body surface patch is provided, which is attachable on a body surface to add a look of fullness to the body surface, exhibits excellent followability to skin deformation, and imposes little burden on body surfaces and thus is widely applicable to body surfaces. The non-sticky body surface patch includes a silicone rubber having a thickness in the range from 50 to 600 μm, wherein the silicone rubber consists of a silicone rubber composition having a rubber hardness of 20 or less measured with a Type A durometer as defined in JIS K6249 standard.
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44.发明申请公开(公告)号：US20210353701A1
公开(公告)日：2021-11-18
申请号：US17290664
申请日：2019-11-01
IPC分类号： A61K36/53 , A61P29/00 , A61K36/899 , A61K36/65 , A61K36/82 , A61K36/738 , A61K36/38 , A61K36/185 , G01N33/50
摘要： The present invention addresses the problem of providing an ultraviolet light-induced inflammation suppressing agent. The present invention is based on the finding that an alternative autophagy (Atg5/Atg7-independent autophagy) participates in the suppression of ultraviolet light-induced inflammation. Thus, the above problem is solved by providing an alternative autophagy inducing agent.
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公开(公告)号：US20210350577A1
公开(公告)日：2021-11-11
申请号：US17273975
申请日：2019-09-04
发明人： Yuji MASUDA , Megumi SEKINO , Hironobu YOSHIKAWA , David Christopher BERENDS , Michael Anthony ISNARDI , Yuzheng ZHANG
摘要： An image analysis device according to the present invention includes: an image capturing unit that captures a subject; a light emitting unit that emits light to the subject; a control unit that causes the image capturing unit to capture a first image of the subject while causing the light emitting unit to emit light and causes the image capturing unit to capture a second image of the subject while not causing the light emitting unit to emit light; and an estimation unit that estimates color of the subject based on a differential value between color information on the first image and the color information on the second image.
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公开(公告)号：US11166887B2
公开(公告)日：2021-11-09
申请号：US16620234
申请日：2018-06-06
摘要： A water-in-oil emulsified cosmetic preparation that, even without substantially comprising a UV scattering agent: exhibits a higher UV protection effect than immediately after application, as a result of coming in contact with moisture, has excellent appearance, usability, and washability. The water-in-oil emulsified cosmetic preparation includes 6%-40% by mass of a UV absorber (A), an oil phase thickener (B), and at least one hydrophobic powder (C) selected from (i)-(iii), namely (i) hydrophobized talc, (ii) silicone powder having an average particle diameter of at least 30 μm, and (iii) crosslinked polymethyl methacrylate powder having a crosslinking density of at least 40%; and not including a UV scattering agent or containing no more than 6% by mass of same.
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公开(公告)号：US20210338552A1
公开(公告)日：2021-11-04
申请号：US17267330
申请日：2019-08-09
摘要： The present invention relates to an oil-based cosmetic having the innovative, unprecedented property in which the ultraviolet protection effects increase due to heat. The oil-based cosmetic of the present invention contains (A) an ultraviolet protectant; and (B) at least one compound that is water-soluble and that has an IOB of 5.0 or lower, selected from among (i) alkylene oxide derivatives and (ii) polyhydric alcohols; wherein the (B) (i) alkylene oxide derivatives are polyoxyalkylene/polyoxyethylene copolymer dialkyl ethers represented by the following formula (I): R1O-[(AO)m(EO)n]—R2 (I) wherein R1 and R2, each independently, denote a hydrogen atom or a hydrocarbon group having one to four carbon atoms, AO denotes an oxyalkylene group having three or four carbon atoms, EO denotes an oxyethylene group, 1≤m≤70, 1≤n≤70 and m+n≤40; and the oil-based cosmetic has a water content of 5% by mass or less.
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公开(公告)号：US20210330574A1
公开(公告)日：2021-10-28
申请号：US17284287
申请日：2019-10-10
发明人： Yukari SAITO , Tomoko IKEDA
摘要： An objective of the present invention is to provide an external preparation for concealing roughness that is easy to spread when applied, while also having effects of concealing roughness such as fine wrinkles. The external preparation for concealing roughness of the present invention comprises (a) 1% to 15% by mass of a wax; and (b) 4% to 25% by mass of a non-spherical powder; and has a viscosity of 50,000 to 150,000 mPa·s.
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公开(公告)号：US20210330573A1
公开(公告)日：2021-10-28
申请号：US17362206
申请日：2021-06-29
发明人： YUKI SUGIYAMA , Ryushi FUKUHARA , Yang HAN
IPC分类号： A61K8/91 , A61K8/06 , A61Q19/00 , C08F290/06 , A61K8/00 , A61Q1/00 , A61Q17/04 , A61K8/86 , A61Q5/00 , A61K8/81
摘要： A method of emulsification of an oil phase in an aqueous continuous phase, by dispersing core-corona microparticles into the aqueous phase, adding the oil phase, and applying shearing force for a time sufficient to emulsify the resulting mixture. The core-corona microparticles are obtained by radical co-polymerization of a polyethylene oxide macromonomer with at least one hydrophobic acrylate monomer and at least one hydrophobic acrylamide monomer.
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公开(公告)号：US11123269B2
公开(公告)日：2021-09-21
申请号：US16320507
申请日：2017-08-07
发明人： Shun Kubota , Hiroki Gomi
IPC分类号： A61K8/02 , A61K8/31 , A61K8/35 , A61K8/36 , A61K8/37 , A61K8/41 , A61K8/49 , A61K8/88 , A61K8/92 , A61Q17/04
摘要： To provide a transparent solid composition having a high ultraviolet ray blocking effect, as well as superior moldability and stability. A transparent solid composition includes: (a) 12-hydroxystearic acid in an amount within a range from 1 to 15% by mass; (b) an oil having a refractive index within a range from 1.5 to 1.7; (c) an oil having a refractive index of 1.3 or greater and less than 1.5; and (d) one type or two or more types of an ultraviolet ray absorbing agent in an amount within a range from 5 to 50% by mass. The refractive index of the transparent solid composition is within a range from 1.47 to 1.55.
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