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公开(公告)号:US10234282B2
公开(公告)日:2019-03-19
申请号:US15643344
申请日:2017-07-06
Applicant: Bruker Nano GmbH , University of Strathclyde
Inventor: Aimo Winkelmann , Stefano Vespucci
IPC: G01N23/203 , G01B15/00 , G01T1/29
Abstract: The present invention refers to a method for determining a position of a divergent radiation source (1), comprising Irradiating a pixel detector (2) with a predetermined intensity distribution of radiation with wavelength λ originated from the radiation source (1), wherein the pixel detector (2) comprises a plurality of pixels with pixel coordinates (xi, yi, zi); Detecting, for each of the plurality of pixels, an intensity of the incident radiation (10); Determining, for each of the plurality of pixels, an incidence direction of the incident radiation using information on an orientation of an internal periodic structure at the pixel and the predetermined intensity distribution, wavelength λ and the detected intensity; and Determining the position (xp, yp, zp) of the radiation source (1) using the pixel coordinates (xi, yi, zi) and the incidence direction for each of the plurality of pixels. The invention further refers to a system, a computer-related product and a sample (8) for performing such method and to the use of a pixel detector (2) for determining a position of a divergent radiation source (1).
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公开(公告)号:US20180010909A1
公开(公告)日:2018-01-11
申请号:US15643344
申请日:2017-07-06
Applicant: Bruker Nano GmbH , University of Strathclyde
Inventor: Aimo WINKELMANN , Stefano VESPUCCI
IPC: G01B15/00 , G01N23/203
CPC classification number: G01B15/00 , G01N23/203 , G01N2223/501 , G01T1/2907
Abstract: The present invention refers to a method for determining a position of a divergent radiation source (1), comprising Irradiating a pixel detector (2) with a predetermined intensity distribution of radiation with wavelength λ originated from the radiation source (1), wherein the pixel detector (2) comprises a plurality of pixels with pixel coordinates (xi, yi, zi); Detecting, for each of the plurality of pixels, an intensity of the incident radiation (10); Determining, for each of the plurality of pixels, an incidence direction of the incident radiation using information on an orientation of an internal periodic structure at the pixel and the predetermined intensity distribution, wavelength λ and the detected intensity; and Determining the position (xp, yp, zp) of the radiation source (1) using the pixel coordinates (xi, yi, zi) and the incidence direction for each of the plurality of pixels. The invention further refers to a system, a computer-related product and a sample (8) for performing such method and to the use of a pixel detector (2) for determining a position of a divergent radiation source (1)
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公开(公告)号:US20180000704A1
公开(公告)日:2018-01-04
申请号:US15547457
申请日:2016-02-01
Applicant: University of Strathclyde
Inventor: Iain OSWALD , Amit DELORI
IPC: A61K8/362 , C09B67/48 , A61Q5/10 , A61K8/365 , A61K8/41 , A61K8/49 , A61K8/46 , C09B67/22 , A61Q5/06
CPC classification number: A61K8/362 , A61K8/365 , A61K8/41 , A61K8/411 , A61K8/46 , A61K8/492 , A61K8/498 , A61K2800/56 , A61Q5/065 , A61Q5/10 , C09B67/0025 , C09B67/0033
Abstract: The present invention discloses new uses of coloured co-crystals and associated salts formed by co-crystallization reactions in the dye, ink and paint industries. The present invention also provides novel co-crystals for use in, for example, the dye, ink and/or paint industries.
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公开(公告)号:US20140348852A1
公开(公告)日:2014-11-27
申请号:US14367088
申请日:2012-12-24
Applicant: University of Strathclyde
Inventor: Jan Vos , Andrew John MacLeod , Barry Douglas Moore
CPC classification number: A61K47/26 , A61K9/145 , A61K9/19 , A61K39/39591 , A61K47/12 , A61K47/183 , A61K2039/505 , C07K16/00 , C07K16/18
Abstract: The present invention relates to the provision of a novel method for preparing dry amorphous precipitated protein particles. In particular to a method provides amorphous precipitated protein particles suitable for use in dry protein formulations which can be reconstituted to provide clear, foam free concentrated protein solutions.
Abstract translation: 本发明涉及提供一种制备干无定形沉淀蛋白质颗粒的新方法。 特别地,一种方法提供适用于干蛋白制剂的无定形沉淀蛋白颗粒,其可重构以提供透明,无泡沫的浓缩蛋白质溶液。
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公开(公告)号:US20140320859A1
公开(公告)日:2014-10-30
申请号:US14358653
申请日:2012-11-21
Applicant: University of Strathclyde
Inventor: Suresh N. Thennadil , Yi-Chieh Chen
CPC classification number: G01N21/03 , G01N21/0303 , G01N21/4738 , G01N21/55 , G01N21/59 , G01N2021/0307 , G01N2021/4742 , G01N2021/4769 , G01N2021/4783 , G01N2021/558 , G01N2201/065
Abstract: A measurement system (5) comprises a radiation source (10) and a detection system (15), wherein the radiation source is arranged such that radiation from the radiation source is incident on a sample (25) and the detection system is configured to receive at least part of the radiation via the sample, wherein the system is reconfigurable so as to vary a path length that the radiation travels through the sample and/or a reflectance of at least one surface upon which the radiation is incident after passing through at least part of the sample. A property of the sample may be determined based on at least the first and second measurements.
Abstract translation: 测量系统(5)包括辐射源(10)和检测系统(15),其中所述辐射源被布置成使得来自所述辐射源的辐射入射到样品(25)上,并且所述检测系统被配置为接收 经由样品的辐射的至少一部分,其中该系统是可重构的,以便改变辐射穿过样品的路径长度和/或至少一个表面的反射率,在至少一个表面上通过至少一个表面 部分样本。 可以至少基于第一和第二测量来确定样品的性质。
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公开(公告)号:US20040235730A1
公开(公告)日:2004-11-25
申请号:US10657404
申请日:2003-09-08
Applicant: University of Strathclyde
Inventor: Gavin William Halbert , Moira Doreen Owens , George Baillie
IPC: A61K038/17 , C07K014/775
CPC classification number: A61K9/1275 , A61K38/00 , C07K14/775
Abstract: Non-naturally occurring lipoprotein particles, process for preparing such particles and uses thereof.
Abstract translation: 非天然存在的脂蛋白颗粒,制备这种颗粒的方法及其用途。
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公开(公告)号:US20030004959A1
公开(公告)日:2003-01-02
申请号:US10121502
申请日:2002-04-12
Applicant: University of Strathclyde
Inventor: Nikolaos Kotsis , Douglas Robert MacGregor
IPC: G06F007/00
CPC classification number: G06F17/30595 , G06F17/3061 , G06F19/00 , Y10S707/99932 , Y10S707/99934
Abstract: A database processor for on-line transaction processing has significantly reduced storage. The processor is arranged to obtain multi-dimensional aggregates of an input relation after a pre-processing stage which identifies aggregates which can be obtained without computation, said pre-processing stage being arranged to: i) identify and store the primary keys derived from the schema of the input relation; ii) establish a Group-by schema generator to generate schemas from minimum arity to maximum arity of aggregate for the possible aggregates of the input relation; iii) sequentially in an arity order beginning with single columns and proceeding in an order in which each lower level of every sub-tree is visited before any root (i.e., breadth-wise from the lowest level to the highest node of the lattice) comparing the generated schemas with the primary keys stored in step (i) augmented by any previous schema identified as being a key and in the event of a generated schema containing a stored key treating the input relation as the virtual representation of the corresponding Group-by aggregate without computation.
Abstract translation: 用于在线事务处理的数据库处理器显着减少了存储。 处理器被安排成在预处理阶段之后获得输入关系的多维聚合,该预处理阶段标识可以在没有计算的情况下获得的聚集,所述预处理阶段被设置为:i)识别并存储从 输入关系模式; ii)建立一个分组式模式生成器,以便从输入关系的可能聚合的最小值到最大的集合生成模式; iii)按照以单列开始的逻辑顺序依次进行,并以每个子树的每个较低级别在任何根(即从网格的最低级到最高级的广度)之间访问的顺序进行比较 在步骤(i)中存储的主密钥的生成模式由被标识为密钥的任何先前模式增加,并且在生成的模式的情况下,将生成的模式包含处理输入关系的存储密钥作为对应的分组聚合的虚拟表示 没有计算。
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公开(公告)号:US20020198212A1
公开(公告)日:2002-12-26
申请号:US10228820
申请日:2002-08-27
Applicant: The University of Strathclyde
IPC: A61K031/525 , C07D475/00
CPC classification number: C07D475/04
Abstract: The present invention relates to the preparation of substantially pure diastereoisomers of derivatives of tetrahydrofolate and the use of such diastereoisomers. More particularly the present invention provides a process for the preparation of a desired substantially pure (6R or 6S) diastereoisomer of a derivative of tetrahydrofolic acid or salt or ester. The process comprises the steps of: attaching a chiral auxiliary group at either N-5 or N-10 of a mixture of 6R and 6S diastereoisomers of tetrahydrofolic acid, separating the new diastereoisomers, recovering the desired new diastereoisomer (6R or 6S) corresponding to the desired (6R or 6S) diastereoisomer, and converting the substantially pure new diastereoisomer recovered into the corresponding diastereoisomer.
Abstract translation: 本发明涉及制备基本上纯的四氢叶酸衍生物的非对映异构体和这种非对映异构体的用途。 更具体地,本发明提供了制备四氢叶酸或其盐或酯衍生物的所需基本上纯的(6R或6S)非对映异构体的方法。 该方法包括以下步骤:将六氢叶酸的6R和6S非对映异构体的混合物的N-5或N-10的手性辅助基团连接,分离新的非对映异构体,回收对应于新的非对映异构体的所需新的非对映异构体(6R或6S) 所需的(6R或6S)非对映异构体,并将基本上纯的新的非对映异构体转化成相应的非对映异构体。
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公开(公告)号:US20250120588A1
公开(公告)日:2025-04-17
申请号:US18723130
申请日:2022-11-28
Applicant: University of Strathclyde
Inventor: Mario E. GIARDINI , Ian COGHILL , Kristy JORDAN , Richard BLACK
IPC: A61B3/14
Abstract: An eye imaging system including: an illumination device configured to illuminate a structure of an eye with a patterned or otherwise textured image; one or more image collection devices wherein; the one or more image collection devices are arranged to capture one or more images of the structure of the eye from one of a plurality of physical locations and/or from different perspectives, e.g. the capture images of the structure of the eye whilst the structure of the eye is illuminated by the patterned or otherwise textured image.
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公开(公告)号:US12188967B2
公开(公告)日:2025-01-07
申请号:US17788158
申请日:2020-12-22
Applicant: University of Strathclyde
Inventor: Pawel Niewczas , Grzegorz Fusiek
Abstract: The invention enables an optical voltage sensor, comprising a piezoelectric actuator mechanically coupled to an optical strain sensor (such as a fibre Bragg grating), to withstand lightning impulses, the effects of which would otherwise be harmful or destructive to the piezoelectric actuator and/or other sensitive components. As such, the optical voltage sensor, comprised within a photonic voltage transducer which also comprises a lightning impulse attenuator, is able to comply with relevant standards and be used for applications in power networks and exposed to the highest voltages for equipment.
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