公开(公告)号：US20050255481A1

公开(公告)日：2005-11-17

申请号：US10843717

申请日：2004-05-11

Applicant: Xiao-Jun Ma ,  Edward Enright ,  Mark Erlander

Inventor： Xiao-Jun Ma ,  Edward Enright ,  Mark Erlander

IPC: C12Q1/68 ,  C12Q1/00 ,  C07H21/04 ,  C07K14/72 ,  C12N15/09

CPC classification number: C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/112 ,  C12Q2600/156

Abstract: The invention relates to the identification and use of sequences from expressed progesterone receptor transcripts in relation to breast cancer. In particular, the invention provides the identities of polynucleotide sequences that may be used to identify populations that are positive for estrogen receptor expression. The expressed polynucleotide sequences may be used in the study and/or diagnosis of cells and tissue in breast cancer as well as for the study and/or determination of prognosis of a patient.

Abstract translation: 本发明涉及鉴定和使用与乳腺癌相关的来自表达的孕酮受体转录物的序列。 特别地，本发明提供可用于鉴定对雌激素受体表达呈阳性的群体的多核苷酸序列的身份。 表达的多核苷酸序列可用于研究和/或诊断乳腺癌中的细胞和组织，以及用于研究和/或确定患者的预后。

公开(公告)号：US09447470B2

公开(公告)日：2016-09-20

申请号：US12718973

申请日：2010-03-06

Applicant: Mark G. Erlander ,  Xiao-Jun Ma ,  Dennis C. Sgroi

Inventor： Mark G. Erlander ,  Xiao-Jun Ma ,  Dennis C. Sgroi

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/112

Abstract: The disclosure includes the identification and use of gene expression profiles, or patterns, with clinical relevance to cancer. In particular, the disclosure includes the identities of genes that are expressed in correlation with tumor grade. The levels of gene expression are disclosed as a molecular index for determining tumor grade in a patient and predicting clinical outcome, and so prognosis, for the patient. The molecular grading of cancer may optionally be used in combination with a second molecular index for diagnosing cancer and its prognosis. The disclosure further includes methods for predicting cancer recurrence, and/or predicting occurrence of metastatic cancer. For diagnosis or prognosis, the disclosure further includes methods for determining or selecting the treatment of cancer based upon the likelihood of life expectancy, cancer recurrence, and/or cancer metastasis.

Abstract translation: 该公开内容包括鉴定和使用与癌症具有临床相关性的基因表达谱或模式。 特别地，本公开包括与肿瘤等级相关表达的基因的身份。 公开了基因表达水平作为确定患者肿瘤分级的分子指标，并预测了患者的临床结果以及预后。 癌症的分子分级可以任选地与用于诊断癌症及其预后的第二分子指数组合使用。 本公开还包括用于预测癌症复发和/或预测转移性癌症发生的方法。 为了诊断或预后，本公开还包括基于预期寿命，癌症复发和/或癌症转移的可能性来确定或选择癌症治疗的方法。

公开(公告)号：US08773989B2

公开(公告)日：2014-07-08

申请号：US13320603

申请日：2010-05-18

Applicant: Yong He ,  Xiao-Jun Ma ,  Jun Li

Inventor： Yong He ,  Xiao-Jun Ma ,  Jun Li

IPC: H04L12/26

CPC classification number: H04W74/0841

Abstract: A method and system are described including retrieving a sparseness indication, retrieving an indication of a number of failed transmissions, comparing the sparseness indication to an optimal sparseness, comparing the number of failed transmissions to a first threshold, adjusting a size of a set of triggering events responsive to both the first and the second comparison, comparing a data buffer push rate to a data buffer arrival rate, further adjusting the size of the triggering set responsive to the third comparison, determining system fairness, comparing the size of the triggering set to a second threshold and further adjusting the size of the triggering set responsive to one of the determination and a combination of the determination and the fourth comparison.

Abstract translation: 描述了一种方法和系统，包括检索稀疏指示，检索多个故障传输的指示，将稀疏指示与最佳稀疏比较，将失败传输的数量与第一阈值进行比较，调整一组触发的大小 响应于第一和第二比较的事件，将数据缓冲器推送速率与数据缓冲器到达速率进行比较，响应于第三比较进一步调整触发集合的大小，确定系统公平性，将触发集合的大小与 第二阈值，并且响应于所述确定中的一个和所述确定和所述第四比较的组合进一步调整所述触发集合的大小。

公开(公告)号：US08755281B2

公开(公告)日：2014-06-17

申请号：US13320616

申请日：2010-05-18

Applicant: Yong He ,  Xiao-Jun Ma ,  Jun Li

Inventor： Yong He ,  Xiao-Jun Ma ,  Jun Li

IPC: G01R31/08

CPC classification number: H04L47/14 ,  H04W74/085

Abstract: A method and apparatus are described including determining a target congestion index, determining a congestion index based on information from a last back-off round, comparing the target congestion index with the congestion index, performing one of increasing a triggering set size by a first factor and decreasing the triggering set size by a second factor responsive to the comparison, determining if a communications medium is idle, adjusting a back-off counter responsive to the third determining act, determining if the back-off counter is equal to a triggering point in the triggering set and transmitting data responsive to the fourth determining act.

Abstract translation: 描述了一种方法和装置，包括确定目标拥塞指标，基于来自最后回退轮的信息确定拥塞指数，将目标拥塞指数与拥塞指数进行比较，执行将触发集大小增加第一因子 以及响应于所述比较将所述触发设置大小减小第二因素，确定通信介质是否空闲，响应于所述第三确定动作来调整回退计数器，确定所述退避计数器是否等于所述触发点的触发点 响应于第四确定动作的触发设置和发送数据。

公开(公告)号：US08737425B2

公开(公告)日：2014-05-27

申请号：US12452162

申请日：2007-06-22

Applicant: Charles Chunaming Wang ,  Jun Li ,  Huanqiang Zhang ,  Zhigang Zhang ,  Xiao-Jun Ma ,  Yong He

Inventor： Charles Chunaming Wang ,  Jun Li ,  Huanqiang Zhang ,  Zhigang Zhang ,  Xiao-Jun Ma ,  Yong He

IPC: H04L12/43 ,  H04L12/413 ,  H04Q11/04

CPC classification number: H04L12/413 ,  H04Q11/04 ,  H04W74/0875

Abstract: A method and apparatus are described for gaining access to a communication medium in a contention-based network, including determining a slot count based on a number of stations in the contention-based network, adjusting the slot count, initiating a frame transmission when the slot count reaches a predetermined value and wherein said number of stations and an address queue are adjusted to reflect one of a priority and traffic patterns. Further, a method and apparatus are described for gaining access to a communication medium in a contention-based network, including receiving a slot count based on a number of stations in the contention-based network, adjusting the slot count, initiating a frame transmission when the slot count reaches a predetermined value and wherein said number of stations and an address queue are adjusted to reflect a priority.

Abstract translation: 描述了一种用于在基于竞争的网络中获取对通信介质的访问的方法和装置，包括基于在基于竞争的网络中的站数量来确定时隙计数，调整时隙计数，当时隙发起帧传输 计数达到预定值，并且其中调整所述站数和地址队列以反映优先级和业务模式之一。 此外，描述了一种用于在基于竞争的网络中获取对通信介质的访问的方法和装置，包括基于在基于竞争的网络中的站点数目接收时隙计数，调整时隙计数，启动帧传输， 时隙计数达到预定值，并且其中所述站数和地址队列被调整以反映优先级。

公开(公告)号：US08683049B2

公开(公告)日：2014-03-25

申请号：US12737095

申请日：2009-06-05

Applicant: Ren Lei Chen ,  Xiao Jun Ma ,  Guang Hua Zhou ,  Jun Li

Inventor： Ren Lei Chen ,  Xiao Jun Ma ,  Guang Hua Zhou ,  Jun Li

IPC: G06F15/16

CPC classification number: H04L12/185

Abstract: The present invention provides a method for sending a message to a network device with a specific MAC address, in an IP network implementing a interne group management protocol IGMP, comprising: sending, by a network terminal, to the network device, a multicast group management status message including a destination address set as the specific MAC address.

Abstract translation: 本发明提供了一种在实现国际组织管理协议IGMP的IP网络中向具有特定MAC地址的网络设备发送消息的方法，包括：由网络终端向网络设备发送组播组管理 状态消息，包括设置为特定MAC地址的目的地址。

公开(公告)号：US08656241B2

公开(公告)日：2014-02-18

申请号：US12995587

申请日：2009-05-27

Applicant: Hang Liu ,  Huanqiang Zhang ,  Xiao-jun Ma ,  Mingquan Wu ,  Jun Li

Inventor： Hang Liu ,  Huanqiang Zhang ,  Xiao-jun Ma ,  Mingquan Wu ,  Jun Li

IPC: H04L1/18 ,  G08C25/02

CPC classification number: H04W4/06 ,  H04L1/1819 ,  H04L1/1848 ,  H04L1/188 ,  H04L2001/0093 ,  H04W4/08 ,  H04W8/26 ,  H04W28/04 ,  H04W72/005

Abstract: A method and apparatus are described including determining address using an access point address and a multicast group address, transmitting a recovery request message to a recovery server to request recovery data using the address and receiving the recovery data from the recovery server. Also described are a method and apparatus including receiving a registration message, transmitting a reply to the registration message, receiving a recovery request message, transmitting recovery data responsive to the recovery request message and transmitting a message to a recovery multicast group to determine status of the recovery multicast group.

Abstract translation: 描述了一种方法和装置，包括使用接入点地址和多播组地址确定地址，向恢复服务器发送恢复请求消息以使用该地址请求恢复数据并从恢复服务器接收恢复数据。 还描述了一种方法和装置，包括接收注册消息，发送对注册消息的回复，接收恢复请求消息，响应于恢复请求消息发送恢复数据，并向恢复组播组发送消息以确定 恢复组播组。

公开(公告)号：US20120258442A1

公开(公告)日：2012-10-11

申请号：US13083552

申请日：2011-04-09

Applicant: Mark Erlander ,  Xiao-Jun Ma

Inventor： Mark Erlander ,  Xiao-Jun Ma

IPC: C12Q1/70 ,  C12Q1/68

CPC classification number: C12Q1/6888 ,  C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/158 ,  C12Q2600/16

Abstract: The disclosure provides methods for the use of gene expression measurements to classify or identify among 54 cancer types in samples obtained from a subject in a clinical setting, such as in cases of formalin fixed, paraffin embedded (FFPE) samples.

Abstract translation: 本公开提供了使用基因表达测量法在例如在福尔马林固定，石蜡包埋（FFPE）样品的情况下从临床环境中从受试者获得的样品中的54种癌症类型中进行分类或鉴定的方法。

公开(公告)号：US20120196761A1

公开(公告)日：2012-08-02

申请号：US13196818

申请日：2011-08-02

Applicant: XIAO-JUN MA ,  Mark Erlander ,  Sgroi Dennis

Inventor： XIAO-JUN MA ,  Mark Erlander ,  Sgroi Dennis

IPC: C40B30/04 ,  C12Q1/68

CPC classification number: C07K14/4748 ,  C07K14/47 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/112 ,  C12Q2600/158 ,  G01N33/57415 ,  G01N2333/96494 ,  G01N2800/52 ,  G01N2800/54

Abstract: The disclosure includes the use of gene expression profiles, or patterns, with clinical relevance to breast cancer. In particular, the disclosure provides the identities of genes that are expressed in correlation with the presence of breast cancer, the grade of breast cancer, and the type of breast cancer. The disclosed methods assist in the detection and identification of breast cancer in a patient and so helps determine treatment and clinical outcome, and so prognosis, for the patient. The gene expression levels, whether embodied in nucleic acid expression, protein expression, or other expression formats, may be used detect the presence of in situ or invasive breast cancer.

Abstract translation: 本公开包括使用与乳腺癌临床相关的基因表达谱或模式。 特别地，本公开提供了与乳腺癌的存在，乳腺癌的级别和乳腺癌的类型相关表达的基因的身份。 所公开的方法有助于检测和鉴定患者中的乳腺癌，因此有助于确定患者的治疗和临床结果以及预后。 可以使用基因表达水平，无论是体现在核酸表达，蛋白质表达或其他表达形式中，都可以检测原位或浸润性乳腺癌的存在。

公开(公告)号：US08193952B2

公开(公告)日：2012-06-05

申请号：US12737936

申请日：2009-09-04

Applicant: Ren Lei Chen ,  Guang Hua Zhou ,  Wen Juan Song ,  Xiao Jun Ma

Inventor： Ren Lei Chen ,  Guang Hua Zhou ,  Wen Juan Song ,  Xiao Jun Ma

IPC: H03M7/00

CPC classification number: G06F17/2247 ,  G06F17/2252 ,  H03M7/3084

Abstract: It provides a method for encoding a set of elements by using components defining the structure of each of the set of elements, wherein each element comprises data structure information and at least one data value. The method comprises the steps of: selecting a current element for encoding; determining whether the current element has the same data structure information as a previously encoded element; in the negative, encoding the data structure information of the current element and the at least one data value of the current element; and in the affirmative, encoding the at least one data value of the current element and providing an indication value associated with the current element indicating the current element has the same data structure information as said previously encoded element. The method is used to reduce the encoding redundancy of the structure information.

Abstract translation: 它提供了一种通过使用定义每组元素的结构的组件对一组元素进行编码的方法，其中每个元素包括数据结构信息和至少一个数据值。 该方法包括以下步骤：选择当前要编码的元素; 确定当前元素是否具有与先前编码的元素相同的数据结构信息; 否则，对当前元素的数据结构信息和当前元素的至少一个数据值进行编码; 并且肯定地，编码当前元素的至少一个数据值并提供与指示当前元素的当前元素相关联的指示值具有与所述先前编码元素相同的数据结构信息。 该方法用于减少结构信息的编码冗余度。