公开(公告)号：US07118900B2

公开(公告)日：2006-10-10

申请号：US10176551

申请日：2002-06-21

Applicant: Michael Seul ,  Sukanta Banerjee ,  Kairali Podual ,  Ye Hong

Inventor： Michael Seul ,  Sukanta Banerjee ,  Kairali Podual ,  Ye Hong

IPC: C12N11/04

CPC classification number: C08J3/075 ,  C08J3/28 ,  C08J2333/26 ,  C08J2425/06 ,  C12Q1/6837 ,  G01N33/5005 ,  G01N33/545 ,  G03F7/0047 ,  G03F7/164 ,  Y10T428/249952 ,  Y10T428/25

Abstract: The present invention relates to a systematic process for the creation of functionally organized, spatially patterned assemblies of polymer-microparticle composites including the AC electric field-mediated assembly of patterned, self-supporting organic (polymeric) films and organic-polymer-microparticle composites of tailored composition and morphology. The present invention further relates to the incorporation of said assemblies into other structures. The present invention also relates to the application of such functional assemblies in materials science and biology. Additional areas of application include sensors, catalysts, membranes, and micro-reactors, and miniaturized format for generation of multifunctional thin films. This invention also provides simple methods and apparatus for synthesizing thin films of tailored composition and morphology.

Abstract translation: 本发明涉及一种用于创建聚合物 - 微粒复合材料的功能组织的，空间上图案化的组件的系统方法，其包括图案化的自支撑有机（聚合物）膜和有机 - 聚合物 - 微粒复合材料的AC电场介导组装 定制组合和形态。 本发明还涉及将所述组件结合到其它结构中。 本发明还涉及这种功能组件在材料科学和生物学中的应用。 其他应用领域包括传感器，催化剂，膜和微反应器以及用于产生多功能薄膜的小型化形式。 本发明还提供用于合成定制组合物和形态的薄膜的简单方法和装置。

公开(公告)号：US09360594B2

公开(公告)日：2016-06-07

申请号：US13985109

申请日：2012-02-23

Applicant: Yuwen Liu ,  Charlie Chen ,  Ye Hong ,  Charles A. Francis ,  Li Yao ,  Arthur Back

Inventor： Yuwen Liu ,  Charlie Chen ,  Ye Hong ,  Charles A. Francis ,  Li Yao ,  Arthur Back

IPC: C08L101/14 ,  G02B1/04 ,  G02C7/04 ,  C08G77/04 ,  C08L51/08 ,  C08F283/06

CPC classification number: G02B1/043 ,  C08F283/065 ,  C08L51/085 ,  C08L101/14

Abstract: Silicone hydrogel contact lenses having a high water content are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): wherein m of formula (1) represents one integer from 3 to 10, n of formula (1) represents one integer from 1 to 10, R1 of formula (1) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (1) is independently either a hydrogen atom or a methyl group; the lenses also include units derived from a second siloxane monomer having a number average molecular weight of at least 7,000 daltons, and at least one vinyl-containing cross-linking agent. The lenses have average equilibrium water contents from about 30% wt/wt to about 70% wt/wt when fully hydrated. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.

Abstract translation: 描述了具有高水含量的硅氧烷水凝胶隐形眼镜。 透镜衍生自包含由式（1）表示的第一硅氧烷单体的可聚合组合物：其中式（1）的m表示3至10的一个整数，式（1）的n表示1至10的整数，R 1 式（1）的烷基是碳原子数为1〜4的烷基，式（1）的各R 2独立地为氢原子或甲基。 透镜还包括衍生自数均分子量为至少7,000道尔顿的第二硅氧烷单体的单元和至少一种含乙烯基交联剂。 当完全水合时，透镜具有约30重量％至约70重量％的平均水含量。 还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

公开(公告)号：US08642677B2

公开(公告)日：2014-02-04

申请号：US13404028

申请日：2012-02-24

Applicant: Guigui Wang ,  Yun Zhang ,  Yuwen Liu ,  Ye Hong ,  Charlie Chen ,  Peter Zhu

Inventor： Guigui Wang ,  Yun Zhang ,  Yuwen Liu ,  Ye Hong ,  Charlie Chen ,  Peter Zhu

IPC: C08F8/00

CPC classification number: G02B1/043 ,  A45C11/005 ,  B65D81/22 ,  C08L83/04

Abstract: Hydrogel contact lenses that are derived from a polymerizable composition including at least one hydrophilic monomer and at least one phosphine-containing component are described. The hydrogel of the contact lenses can be a silicone hydrogel or a non-silicone hydrogel. Use of polymerizable compositions comprising a phosphine-containing component can be cured under both inert and air atmospheres, and can be used to form hydrogel contact lenses having improved shape retention properties, having improved resistance to discoloration. Batches of hydrogel contact lenses and methods of making hydrogel contact lenses are also described.

Abstract translation: 描述了衍生自包含至少一种亲水性单体和至少一种含膦组分的可聚合组合物的水凝胶隐形眼镜。 隐形眼镜的水凝胶可以是硅酮水凝胶或非硅氧水凝胶。 包含含膦组分的可聚合组合物的使用可以在惰性和空气气氛下固化，并且可用于形成具有改善的变色保持性能的具有改进的抗变色性的水凝胶隐形眼镜。 还描述了水凝胶隐形眼镜的批次和制备水凝胶隐形眼镜的方法。

公开(公告)号：US08476337B2

公开(公告)日：2013-07-02

申请号：US12496228

申请日：2009-07-01

Applicant: Charlie Chen ,  Ye Hong ,  Nick Manesis

Inventor： Charlie Chen ,  Ye Hong ,  Nick Manesis

IPC: G02C7/04 ,  C08G77/06

CPC classification number: C08L83/14 ,  G02B1/043

Abstract: Silicone hydrogel contact lenses having ophthalmically acceptable surface wettabilities are obtained from pre-extracted polymerized silicone hydrogel contact lens products having relatively large amounts of removable or extractable materials. The silicone hydrogel contact lenses can be obtained from non-polar resin based contact lens molds and without surface treatments or an interpenetrating polymeric network of a polymeric wetting agent. Related lens products, polymerizable compositions, and methods are also described.

公开(公告)号：US07572841B2

公开(公告)日：2009-08-11

申请号：US11761324

申请日：2007-06-11

Applicant: Charlie Chen ,  Ye Hong ,  Nick Manesis

Inventor： Charlie Chen ,  Ye Hong ,  Nick Manesis

IPC: G02C7/04 ,  C08G77/14 ,  C08F290/06

CPC classification number: C08L83/14 ,  G02B1/043

Abstract: Silicone hydrogel contact lenses having ophthalmically acceptable surface wettabilities are obtained from pre-extracted polymerized silicone hydrogel contact lens products having relatively large amounts of removable or extractable materials. The silicone hydrogel contact lenses can be obtained from non-polar resin based contact lens molds and without surface treatments or an interpenetrating polymeric network of a polymeric wetting agent. Related lens products, polymerizable compositions, and methods are also described.

Abstract translation: 具有眼科可接受的表面润湿性的硅酮水凝胶隐形眼镜由具有相对大量的可移除或可萃取材料的预提取聚合的硅氧水凝胶隐形眼镜产品获得。 硅酮水凝胶隐形眼镜可以从非极性树脂基隐形眼镜模具获得，而不用表面处理或聚合润湿剂的互穿聚合物网络获得。 还描述了相关的透镜产品，可聚合组合物和方法。

公开(公告)号：US07540609B2

公开(公告)日：2009-06-02

申请号：US11761272

申请日：2007-06-11

Applicant: Charlie Chen ,  Ye Hong ,  Nick Manesis

Inventor： Charlie Chen ,  Ye Hong ,  Nick Manesis

IPC: G02C7/04 ,  G02B1/04 ,  C08F290/08 ,  C08G77/04

CPC classification number: C08L83/14 ,  C08F283/12 ,  C08F290/068 ,  C08L51/085 ,  G02B1/043 ,  C08L2666/02

Abstract: Silicone hydrogel contact lenses having ophthalmically acceptable surface wettabilities are obtained from pre-extracted polymerized silicone hydrogel contact lens products produced from a polymerizable composition comprising a combination of particular components. The silicone hydrogel contact lenses can be obtained from non-polar resin based contact lens molds and without surface treatments or an interpenetrating polymeric network of a polymeric wetting agent. Related lens products, polymerizable compositions, and methods are also described.

Abstract translation: 具有眼睛可接受的表面润湿性的硅酮水凝胶隐形眼镜是由包含特定组分的组合的可聚合组合物制备的预提取聚合的硅氧水凝胶隐形眼镜产品获得的。 硅酮水凝胶隐形眼镜可以从非极性树脂基隐形眼镜模具获得，而不用表面处理或聚合润湿剂的互穿聚合物网络获得。 还描述了相关的透镜产品，可聚合组合物和方法。

公开(公告)号：US20080048350A1

公开(公告)日：2008-02-28

申请号：US11761324

申请日：2007-06-11

Applicant: Charlie Chen ,  Ye Hong ,  Nick Manesis

Inventor： Charlie Chen ,  Ye Hong ,  Nick Manesis

IPC: C08F290/06 ,  B29D11/00

CPC classification number: C08L83/14 ,  G02B1/043

Abstract: Silicone hydrogel contact lenses having ophthalmically acceptable surface wettabilities are obtained from pre-extracted polymerized silicone hydrogel contact lens products having relatively large amounts of removable or extractable materials. The silicone hydrogel contact lenses can be obtained from non-polar resin based contact lens molds and without surface treatments or an interpenetrating polymeric network of a polymeric wetting agent. Related lens products, polymerizable compositions, and methods are also described.

Abstract translation: 具有眼科可接受的表面润湿性的硅酮水凝胶隐形眼镜由具有相对大量的可移除或可萃取材料的预提取聚合的硅氧水凝胶隐形眼镜产品获得。 硅酮水凝胶隐形眼镜可以从非极性树脂基隐形眼镜模具获得，而不用表面处理或聚合润湿剂的互穿聚合物网络获得。 还描述了相关的透镜产品，可聚合组合物和方法。