Free reactant use in nucleic acid-templated synthesis
    42.
    发明申请
    Free reactant use in nucleic acid-templated synthesis 有权
    自由反应物用于核酸模板合成

    公开(公告)号:US20060223086A1

    公开(公告)日:2006-10-05

    申请号:US11336405

    申请日:2006-01-20

    IPC分类号: C12Q1/68 C12P19/34

    CPC分类号: C07H21/00

    摘要: The present invention provides methods and compositions for expanding the scope of chemical reactions that can be performed during nucleic acid-templated organic syntheses. In particular, nucleic acid-templated chemistries are used to produce reaction intermediates attached to an oligonucleotide that can be used to identify the reaction intermediates and/or the resulting reaction products. The reaction intermediates then are reacted with free reactants (for example, reactants that are difficult or impractical to couple to an oligonucleotide) to produce a reaction product. This approach expands the scope of reagents useful in nucleic acid-templated syntheses to reagents that do not need to be or cannot be tethered to an oligonucleotide. The reagents, however, still permit the synthesis of reaction products attached to oligonucleotides that can be used to identify the reaction products.

    摘要翻译: 本发明提供用于扩大可以在核酸模板化有机合成过程中进行的化学反应范围的方法和组合物。 特别地,核酸模板化学物质用于产生连接到寡核苷酸上的反应中间体,其可用于鉴定反应中间体和/或所得反应产物。 然后将反应中间体与游离反应物(例如,与寡核苷酸偶联困难或不切实际的反应物)反应以产生反应产物。 这种方法将可用于核酸模板合成的试剂的范围扩大到不需要或不能束缚于寡核苷酸的试剂。 然而,试剂仍然允许合成与可用于鉴定反应产物的寡核苷酸连接的反应产物。

    Combination advanced corneal to topography/wave front aberration measurement
    45.
    发明授权
    Combination advanced corneal to topography/wave front aberration measurement 失效
    组合高级角膜到地形/波前像差测量

    公开(公告)号:US06428168B2

    公开(公告)日:2002-08-06

    申请号:US09860558

    申请日:2001-05-21

    IPC分类号: A61B310

    摘要: A method and apparatus for the simultaneous measurement of the anterior and posterior corneal surfaces, corneal thickness, and optical aberrations of the eye. The method employs direct measurements and ray tracing to provide a wide range of measurements for use by the ophthalmic community.

    摘要翻译: 用于同时测量前角膜和后角膜表面,角膜厚度和眼睛的光学像差的方法和装置。 该方法采用直接测量和光线跟踪,以提供广泛的测量范围,供眼科社区使用。

    Health care shoe
    46.
    发明授权
    Health care shoe 失效
    保健鞋

    公开(公告)号:US6151807A

    公开(公告)日:2000-11-28

    申请号:US240791

    申请日:1999-01-30

    IPC分类号: A43B7/00 A61F5/14 A13B7/06

    CPC分类号: A43B7/146 A43B1/0054 A43B7/00

    摘要: A health care shoe, which can continuously provide adequate magnetic field arranged to penetrate through the wearer's foot for improving the wearer's blood circulation and metabolism, includes a sole having a plurality of magnet cavities specifically indented and distributed on an inner surface thereof, a shoe body which includes a vamp and sides rigidly attached on top of the sole to define a foot chamber between the shoe body and the sole; an insole placed on the sole inside the foot chamber; a plurality of base magnet elements fittingly received in the magnet cavities respectively; and a plurality of upper magnet elements embedded inside the shoe body with respect to the positions of the base magnet elements, wherein the upper magnet elements are arranged to enable magnetic fields flowing between the base magnet elements and the upper magnet elements. Moreover, the sole further has at least a medicine receiving cavity to receive a medicine unit which contains a medicine tablet made of painkiller or Chinese medical herb being incased therein. The medicine unit further includes a bottom magnet element positioned thereunder so as to produce magnetic filed around the medicine unit.

    摘要翻译: 一种能够连续地提供足够的磁场以穿透穿戴者的脚部以改善佩戴者的血液循环和新陈代谢的保健鞋,包括具有多个在其内表面上凹进并分布的磁体空腔的鞋底,鞋体 其包括鞋面和刚性地附接在鞋底顶部上的侧边,以在鞋身和鞋底之间限定脚室; 放置在脚室内的鞋底上的鞋垫; 多个基本磁体元件分别适配地容纳在磁体腔中; 以及相对于所述基体磁体元件的位置嵌入到所述鞋体内的多个上部磁体,其中,所述上部磁体元件被布置成使得能够在所述基础磁体元件和所述上部磁体元件之间流动的磁场。 此外,鞋底还具有至少一个药物容纳腔,以容纳药物单元,该药物单元含有由止痛药制成的药片或其中含有的中草药。 药物单元还包括位于其下方的底部磁体元件,以便产生药物单元周围的磁场。

    Plasma cleaning method for removing residues in a plasma treatment
chamber
    47.
    发明授权
    Plasma cleaning method for removing residues in a plasma treatment chamber 失效
    用于去除等离子体处理室中的残留物的等离子体清洁方法

    公开(公告)号:US5356478A

    公开(公告)日:1994-10-18

    申请号:US176935

    申请日:1994-01-03

    摘要: A plasma cleaning method for removing residues previously formed in a plasma treatment chamber by dry etching layers such as photoresist, barriers, etc., on a wafer. The method includes introducing a cleaning gas mixture of an oxidizing gas and a chlorine containing gas into the chamber followed by performing a plasma cleaning step. The plasma cleaning step is performed by activating the cleaning gas mixture and forming a plasma cleaning gas, contacting interior surfaces of the chamber with the plasma cleaning gas and removing residues on the interior surfaces. The cleaning gas mixture can also include a fluorine-based gas. For instance, the cleaning gas can include Cl.sub.2 and O.sub.2 and optionally CF.sub.4. An advantage of the cleaning method is that it is not necessary to open the plasma treatment chamber. Also, it is possible to completely remove all residues and prevent by-products formed during the cleaning step from remaining after the cleaning step.

    摘要翻译: 一种等离子体清洗方法,用于通过诸如光致抗蚀剂,阻挡层等的干蚀刻层去除等离子体处理室中先前形成的残留物。 该方法包括将氧化气体和含氯气体的清洁气体混合物引入室中,然后执行等离子体清洗步骤。 通过激活清洁气体混合物并形成等离子体清洁气体,使室的内表面与等离子体清洁气体接触并除去内表面上的残留物来进行等离子体清洗步骤。 清洁气体混合物还可以包括氟基气体。 例如,清洁气体可以包括Cl 2和O 2以及任选的CF 4。 清洗方法的优点在于不需要打开等离子体处理室。 此外,可以完全除去所有残留物并且防止在清洁步骤后形成的副产物在清洁步骤之后残留。

    Plasma apparatus including dielectric window for inducing a uniform
electric field in a plasma chamber
    48.
    发明授权
    Plasma apparatus including dielectric window for inducing a uniform electric field in a plasma chamber 失效
    等离子体设备包括用于在等离子体室中诱导均匀电场的介电窗口

    公开(公告)号:US5226967A

    公开(公告)日:1993-07-13

    申请号:US883201

    申请日:1992-05-14

    摘要: An apparatus for plasma etching or plasma deposition including a housing having a chamber in which a wafer can be treated with plasma. The housing includes at least one inlet port connected to an interior of the chamber through which process gas can be supplied to the chamber. A radiofrequency energy source is arranged to pass radiofrequency energy into the chamber and induce plasma in the interior of the chamber by activating, with an electric field induced by the radiofrequency energy source, process gas supplied to the chamber through the inlet port. A dielectric window having an inner surface thereof forms part of an inner wall of the chamber. Radiofrequency energy passes from the radiofrequency energy source to the interior of the chamber through the dielectric window. The dielectric window has a thickness which varies at different points along the inner surface thereof such that the thickness is largest at a central portion of the dielectric window. The dielectric window is effective to decrease the induced electric field in the interior of the chamber near the central portion of the dielectric window.

    摘要翻译: 一种用于等离子体蚀刻或等离子体沉积的装置,包括具有可以用等离子体处理晶片的室的壳体。 壳体包括连接到室的内部的至少一个入口端口,通过该入口端口可将工艺气体供应到室。 射频能源设置成将射频能量传递到腔室中并且通过由射频能量源引起的电场通过入口端口供应到腔室的处理气体进行激活而在腔室的内部引起等离子体。 具有内表面的电介质窗形成室的内壁的一部分。 射频能量通过电介质窗从射频能量传递到腔室的内部。 电介质窗口具有在其内表面的不同点处变化的厚度,使得在电介质窗口的中心部分处的厚度最大。 电介质窗口有效地减小在电介质窗口的中心部分附近的室内的感应电场。