Process for the production of anilines
    42.
    发明授权
    Process for the production of anilines 有权
    生产苯胺的方法

    公开(公告)号:US07737301B2

    公开(公告)日:2010-06-15

    申请号:US12065304

    申请日:2006-08-28

    摘要: The present invention relates to a process for the preparation of compounds of formula wherein R1, R2 and R3 are each independently of the others hydrogen or C1-C4alkyl, by a) reacting compounds of formula (II) wherein R1, R2 and R3 are as defined for formula (I) and X is bromine or chlorine, with a compound of formula (III) wherein R4 is hydrogen or C1-C4alkyl, in the presence of a base and catalytic amounts of at least one palladium complex compound, to form compounds of formula (IV) wherein R1, R2, R3 and R4 are as defined for formula (I), and b) converting those compounds, using a reducing agent, into compounds of formula (I).

    摘要翻译: 本发明涉及制备下式化合物的方法,其中R 1,R 2和R 3各自独立地为氢或C 1 -C 4烷基,通过a)使式(Ⅱ)化合物(其中R 1,R 2和R 3为 与式(Ⅲ)化合物(其中R 4是氢或C 1 -C 4烷基)在碱和催化量的至少一种钯络合物的存在下形成化合物(I),X是溴或氯, 其中R 1,R 2,R 3和R 4如式(I)所定义,并且b)使用还原剂将这些化合物转化为式(I)化合物。

    Heterocyclic amide derivatives useful as microbiocides
    43.
    发明授权
    Heterocyclic amide derivatives useful as microbiocides 有权
    用作杀微生物剂的杂环酰胺衍生物

    公开(公告)号:US07732469B2

    公开(公告)日:2010-06-08

    申请号:US12091189

    申请日:2006-10-23

    摘要: The invention relates to a fungicidally active compound of formula (I): where Het is a 5- or 6-membered heterocyclic ring containing one to three heteroatoms, each independently selected from oxygen, nitrogen and sulphur, the ring being substituted by the groups R6, R7 and R8; R1 is hydrogen, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy, C1-4 haloalkoxy, CH2 C≡CR9, CH2 CR10═CHR11, CH═C═CH2 or COR12; R2 and R3 are each, independently, hydrogen, halo, C1-4 alkyl, C1-4 alkoxy, C1-4 haloalkyl or C1-4 haloalkoxy; R4 and R5 are each independently selected from halo, cyano and nitro; or one of R4 and R5 is hydrogen and the other is selected from halo, cyano and nitro; R6, R7 and R8 are each, independently, hydrogen, halo, cyano, nitro, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy(C1-4)alkyl, C1-4 haloalkoxy(C1-4)alkyl or C1-4 haloalkoxy, provided that at least one of R6, R7 and R8 is not hydrogen; R9, R10 and R11 are each, independently, hydrogen, halo, C1-4 alkyl, C1-4 haloalkyl or C1-4 alkoxy(C1-4)alkyl; and R12 is hydrogen, C1-6 alkyl, C1-6 haloalkyl, C1-4 alkoxy(C1-4)alkyl, C1-4 alkylthio(C1-4)-alkyl, C1-4 alkoxy or aryl; to the preparation of these compounds, to novel intermediates used in the preparation of these compounds, to agrochemical compositions which comprise at least one of the novel compounds as active ingredient, to the preparation of the compositions mentioned and to the use of the active ingredients or compositions in agriculture or horticulture for controlling or preventing infestation of plants by phytopathogenic microorganisms, preferably fungi.

    摘要翻译: 本发明涉及式(I)的杀真菌活性化合物:其中Het是含有一至三个杂原子的5-或6-元杂环,各自独立地选自氧,氮和硫,该环被R6基团取代 ,R7和R8; R 1是氢,C 1-4烷基,C 1-4卤代烷基,C 1-4烷氧基,C 1-4卤代烷氧基,CH 2C≡CR9,CH 2 CR 10 = CHR 11,CH = C = CH 2或COR 12; R 2和R 3各自独立地为氢,卤素,C 1-4烷基,C 1-4烷氧基,C 1-4卤代烷基或C 1-4卤代烷氧基; R4和R5各自独立地选自卤素,氰基和硝基; 或者R4和R5之一是氢,另一个选自卤素,氰基和硝基; R 6,R 7和R 8各自独立地为氢,卤素,氰基,硝基,C 1-4烷基,C 1-4卤代烷基,C 1-4烷氧基(C 1-4)烷基,C 1-4卤代烷氧基(C 1-4)烷基或 C 1-4卤代烷氧基,条件是R 6,R 7和R 8中的至少一个不是氢; R 9,R 10和R 11各自独立地为氢,卤素,C 1-4烷基,C 1-4卤代烷基或C 1-4烷氧基(C 1-4)烷基; 和R 12是氢,C 1-6烷基,C 1-6卤代烷基,C 1-4烷氧基(C 1-4)烷基,C 1-4烷硫基(C 1-4) - 烷基,C 1-4烷氧基或芳基; 涉及这些化合物的制备,用于制备这些化合物的新型中间体,包括至少一种新化合物作为活性成分的农用化学组合物,所述组合物的制备以及使用活性成分或 用于通过植物病原微生物,优选真菌控制或预防植物感染的农业或园艺成分。

    Process For the Production of Carboxanilides
    44.
    发明申请
    Process For the Production of Carboxanilides 有权
    碳酰苯胺生产工艺

    公开(公告)号:US20080262242A1

    公开(公告)日:2008-10-23

    申请号:US12093619

    申请日:2006-11-13

    IPC分类号: C07D231/14

    CPC分类号: C07D231/14

    摘要: The present invention relates to a novel process for the preparation of a compound of general formula (I): wherein R1 is H or C1-4 alkyl and R2 is difluoromethyl or trifluoromethyl, which comprises reacting a compound of general formula (II): wherein R1 has the meaning given above and X is chloro or bromo, with a compound of general formula (III): wherein R2 has the meaning given above, in the presence of a base, a palladium catalyst and a ferrocenyl biphoshine ligand of the Josiphos type, the reaction being carried out in an ether solvent at a reflux temperature of at least 100° C.

    摘要翻译: 本发明涉及一种制备通式(I)化合物的新方法:其中R 1是H或C 1-4烷基,R SUP 其中R 2是二氟甲基或三氟甲基,其包括使通式(II)的化合物:其中R 1具有上面给出的含义和X是氯或溴的化合物与通式 式(III):其中R 2具有上面给出的含义,在Josiphos型的碱,钯催化剂和二茂铁基二膦配体的存在下,该反应在醚溶剂中进行 在至少100℃的回流温度下

    Insecticidal compounds
    47.
    发明授权
    Insecticidal compounds 有权
    杀虫化合物

    公开(公告)号:US08586593B2

    公开(公告)日:2013-11-19

    申请号:US13382688

    申请日:2010-06-07

    IPC分类号: C07D401/14 A01N43/54

    CPC分类号: C07D401/14 A01N43/54

    摘要: A compound of formula (I) wherein A, p, R1, R3, R4, R5, and R8 are as defined in claim 1. Furthermore, the present invention relates to intermediates used to prepare compounds of formula (I), to methods of using them to combat and control insect, acarine, nematode and mollusc pests and to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising them.

    摘要翻译: 其中A,p,R 1,R 3,R 4,R 5和R 8如权利要求1中所定义的式(I)化合物。此外,本发明涉及用于制备式(I)化合物的中间体, 使用它们来对抗和控制昆虫,螨虫,线虫和软体动物害虫以及包含它们的杀虫,杀螨,杀线虫和杀软体动物的组合物。