公开(公告)号：US20070087452A1

公开(公告)日：2007-04-19

申请号：US11250722

申请日：2005-10-14

申请人： David Parker ,  Paul Atkinson ,  Filip Kielar ,  Annegret Boge ,  J. Sportsman ,  Elizabeth Gaudet ,  George Yi

发明人： David Parker ,  Paul Atkinson ,  Filip Kielar ,  Annegret Boge ,  J. Sportsman ,  Elizabeth Gaudet ,  George Yi

IPC分类号： G01N33/543 ,  C07F5/00 ,  C07D403/02 ,  C07K16/46

CPC分类号： C07D471/04 ,  C07D403/02 ,  C07D471/14 ,  C07D491/04 ,  C07D495/04 ,  C09B57/10 ,  G01N33/582 ,  G01N2458/40 ,  Y10T436/13

摘要： Systems, including compositions, kits, and methods, particularly for photoluminescence applications. The systems may include, among others, (1) organic chelators, (2) complexes between the chelators and lanthanide ions, and (3) precursors, derivatives, and uses thereof. The chelators may include a 1,4,7,10-tetraazacyclododecane ring system, for example, having the formula: Here, R1, R2, and R3 are substituents of the tetraazacyclododecane ring system, that is further substituted at the 10-position by a sensitizer Z that is typically a polyheterocyclic ring system. The organic chelator may be capable of forming a luminescent complex with a lanthanide ion, and is optionally further substituted by a reactive functional group or a conjugated substance. The resulting lanthanide complex may be useful in luminescence-based assays, such as energy transfer assays, among others.

摘要翻译： 系统，包括组合物，试剂盒和方法，特别是用于光致发光应用。 该系统可以包括（1）有机螯合剂，（2）螯合剂和镧系元素离子之间的络合物，和（3）前体，衍生物及其用途。 螯合剂可以包括例如具有下式的1,4,7,10-四氮杂环十二烷环体系：这里，R 1，R 2和R 2 > 3是四氮杂环十二烷环系的取代基，其在10位被通常为多杂环系的敏化剂Z进一步取代。 有机螯合剂可能能够与镧系元素离子形成发光配合物，并且任选地进一步被反应性官能团或共轭物质取代。 所得镧系元素络合物可用于基于发光的测定，例如能量转移测定等。

公开(公告)号：US07195893B2

公开(公告)日：2007-03-27

申请号：US10918602

申请日：2004-08-12

申请人： David Parker ,  Xianghong Xu ,  Afsheen Khawaja ,  Janette Mezeyova ,  Terrance P. Snutch

发明人： David Parker ,  Xianghong Xu ,  Afsheen Khawaja ,  Janette Mezeyova ,  Terrance P. Snutch

IPC分类号： C12P21/06

CPC分类号： C07K14/465

摘要： A new class of α2δ subunits which function in calcium ion channels is described. This class is avian derived.

摘要翻译： 描述了在钙离子通道中起作用的新类型的α2 N 3亚基。 这个类是禽类衍生的。

公开(公告)号：US20070061517A1

公开(公告)日：2007-03-15

申请号：US11226086

申请日：2005-09-13

申请人： Claus Pribbernow ,  David Parker

发明人： Claus Pribbernow ,  David Parker

IPC分类号： G06F12/00

CPC分类号： G06F12/0802 ,  G06F2212/601

摘要： A data-processing system and method include a processor core associated with a cache controller. A plurality of cached memory components is associated with the processor core and the cache controller. A cached processor is provided, which supports a plurality of varying sizes of instruction and data cache, wherein the cached processor comprises a processor core separated from the cache controller and the plurality of cached memory components, thereby permitted the cached processor to support varying sizes of cache memory in a flexible memory arrangement thereof.

摘要翻译： 数据处理系统和方法包括与高速缓存控制器相关联的处理器核心。 多个缓存的存储器组件与处理器核心和高速缓存控制器相关联。 提供了缓存的处理器，其支持多个不同大小的指令和数据高速缓存，其中缓存的处理器包括与高速缓存控制器和多个高速缓存的存储器组件分离的处理器核，从而允许高速缓存的处理器支持不同大小的 缓存存储器在其灵活的存储器布置中。

公开(公告)号：US20070060569A1

公开(公告)日：2007-03-15

申请号：US11591861

申请日：2006-11-02

申请人： Roger Fujimoto ,  Leslie McQuire ,  Lauren Monovich ,  Philippe Nantermet ,  David Parker ,  Leslie Robinson ,  Jerry Skiles ,  Ruben Tommasi

发明人： Roger Fujimoto ,  Leslie McQuire ,  Lauren Monovich ,  Philippe Nantermet ,  David Parker ,  Leslie Robinson ,  Jerry Skiles ,  Ruben Tommasi

IPC分类号： A61K31/55 ,  A61K31/501 ,  A61K31/454 ,  A61K31/4545 ,  C07D409/02 ,  C07D417/02 ,  C07D405/02 ,  C07D403/02

CPC分类号： C07D401/12 ,  C07D211/34 ,  C07D405/14 ,  C07D409/12 ,  C07D409/14 ,  C07D413/14 ,  C07D417/04 ,  C07D417/12

摘要： Compound of the formula wherein R represents OH or NHOH; R1 represents hydrogen, optically substituted lower alkyl, aryl-lower alkyl, cycloalkyl-lower alkyl, or acyl derived from a carboxylic acid, from a carbonic acid, from a carbamic acid or from a sulfonic acid; R2 represents biarylsulfonyl or aryloxyrylsulfonyl; R3 represents hydrogen, optionally substituted lower alkyl, aryl-lower alkyl, cycloalkyl-lower alkyl or acyl derived from a carboxylic acid, from a carbonic acid or from a carbamic acid; R4 and R5 represent independently hydrogen, lower alkyl, lower alkoxycarbonyl, aryl-lower alkyl or cycloalkyl-lower alkyl; m is zero, 1, 2 or 3; pharmaceutically acceptable prodrug derivatives thereof; pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising said compounds; and their use for inhibiting matrix degrading metalloproteinases and preventing or treating matrix metalloproteinase dependent conditions in mammals.

摘要翻译： 下式的化合物其中R表示OH或NHOH; R 1表示氢，光取代的低级烷基，芳基 - 低级烷基，环烷基 - 低级烷基或衍生自羧酸的酰基，来自碳酸，氨基甲酸或磺酸; R 2表示联芳基磺酰基或芳氧基酰基磺酰基; R 3表示氢，任选取代的低级烷基，芳基 - 低级烷基，环烷基 - 低级烷基或衍生自羧酸的酰基，来自碳酸或氨基甲酸; R 4和R 5独立地表示氢，低级烷基，低级烷氧基羰基，芳基 - 低级烷基或环烷基 - 低级烷基; m为零，1,2或3; 其药学上可接受的前药衍生物; 其药学上可接受的盐; 包含所述化合物的药物组合物; 以及它们用于抑制基质降解金属蛋白酶和预防或治疗哺乳动物中基质金属蛋白酶依赖性条件的用途。

公开(公告)号：US20070000228A1

公开(公告)日：2007-01-04

申请号：US11169478

申请日：2005-06-29

申请人： Rajeev Ohri ,  Kristian Wetzl ,  Herbert Reid ,  Arthur Harris ,  David Parker ,  Stephen Mumford

发明人： Rajeev Ohri ,  Kristian Wetzl ,  Herbert Reid ,  Arthur Harris ,  David Parker ,  Stephen Mumford

IPC分类号： F02C3/14

CPC分类号： F23R3/14

摘要： A fuel/air mixing apparatus, such as a main swirler assembly (400) comprising a sleeve (410), provides for additional air entry around the perimeter of a bore (440) through which passes a fuel/air mixture. The additional air reduces or eliminates flashback during operation of a gas turbine comprising the assembly (400). In some embodiments, a plurality of gaps (464) exists between spaced apart tabs (462) along a downstream end (460) of the sleeve (410). During gas turbine operation, air flows through both a flashback annulus (411) and the gaps (464). In other embodiments, a plurality of holes are placed upstream and in line with the tabs (1004) to supplement the air flow through gaps (1006). In yet other embodiments, rows (1102) of holes (1104) are provided to supplement the airflow. Downstream ends (460,1218) may interface with a downstream-oriented lip (460) or with an upstream-oriented lip (1224). The interfacing may comprise a fit effective to damp vibration and to increase the natural frequency.

摘要翻译： 诸如包括套筒（410）的主旋流器组件（400）的燃料/空气混合设备提供围绕通过燃料/空气混合物的孔（440）的周边的附加空气进入。 在包括组件（400）的燃气涡轮机的操作期间，附加空气减少或消除了回火。 在一些实施例中，沿着套筒（410）的下游端（460）的间隔开的突片（462）之间存在多个间隙（464）。 在燃气轮机操作期间，空气流过回流环（411）和间隙（464）。 在其他实施例中，多个孔被放置在上游并且与突片（1004）成一直线，以补充通过间隙（1006）的空气流。 在其它实施例中，提供孔（1104）的孔（1104）以补充气流。 下游端（460,1218）可以与下游定向的唇缘（460）或与上游取向唇缘（1224）相接触。 接口可以包括有效地阻尼振动并增加固有频率的配合。

公开(公告)号：US20060292855A1

公开(公告)日：2006-12-28

申请号：US11160428

申请日：2005-06-23

申请人： Howard Landis ,  David Parker ,  Jeanne-Tania Sucharitaves

发明人： Howard Landis ,  David Parker ,  Jeanne-Tania Sucharitaves

IPC分类号： H01L21/66 ,  G01R31/28 ,  H01L21/4763

CPC分类号： H01L23/528 ,  H01L21/76816 ,  H01L2924/0002 ,  H01L2924/00

摘要： A method, system and program product for replacing isotropic hole shapes in a wiring layout with non-equiaxial hole shapes that are arranged in a direction of current flow, which increases current flow along the wire's longitudinal axis while decreasing current flow along the wire's transverse axis. One aspect of the invention includes a method including determining a direction of electrical current flow in a portion of a wiring layout; and placing at least one non-equiaxial hole shape within the portion of the wiring layout, wherein the non-equiaxial hole shape is arranged in the direction of electrical current flow. The invention accommodates the limitations of copper CMP within an automated tool without sacrificing the efficiency of a hand-tuned layout. The invention also includes a semiconductor device including at least one non-equiaxial hole shape.

摘要翻译： 一种方法，系统和程序产品，用于在沿着电流流动方向布置的非等轴孔形状的布线布局中替换各向同性孔形状，其沿着线的纵向轴线增加电流，同时沿着线的横轴减小电流 。 本发明的一个方面包括一种方法，其包括确定布线布局的一部分中的电流流动的方向; 并且在所述布线布置部分内布置至少一个非等轴孔形状，其中所述非等轴孔形状沿电流流动方向布置。 本发明在自动化工具中适应铜CMP的限制，而不牺牲手动布局的效率。 本发明还包括包括至少一个非等轴孔形状的半导体器件。

公开(公告)号：US20060194060A1

公开(公告)日：2006-08-31

申请号：US11359473

申请日：2006-02-23

申请人： Alan Arico ,  David Parker ,  Akshay Waghray

发明人： Alan Arico ,  David Parker ,  Akshay Waghray

IPC分类号： B32B9/00 ,  B32B17/10 ,  C04B35/64

CPC分类号： F27D5/00 ,  C04B35/522 ,  C04B35/83 ,  C04B2235/9623 ,  Y10T428/30 ,  Y10T428/31

摘要： A set of furnace spacers for spacing a first preform from a second preform, the first and second preforms each having an outer periphery, a width, an inner opening having a periphery and a width, a first side defined by the outer periphery and said inner opening, the first side having a surface area, and a second side spaced from the first side. Each spacer in the set of spacers has a body having a first side having a surface area, and the sum of the first side surface areas of the spacers in a set is greater than about thirty percent of the preform first side surface area.

摘要翻译： 一组用于将第一预成型件与第二预制件间隔开的炉间隔件，所述第一和第二预成型件各自具有外周边，宽度，具有周边和宽度的内部开口，由外周限定的第一侧和所述内部 开口，具有表面积的第一侧和与第一侧间隔开的第二侧。 该组隔离物中的每个间隔物具有主体，该主体具有第一侧面，该主体具有表面积，并且一组中间隔物的第一侧表面积的总和大于预成型件第一侧表面积的大约百分之三十。

公开(公告)号：US20060126349A1

公开(公告)日：2006-06-15

申请号：US11350675

申请日：2006-02-08

申请人： David Parker ,  Kevin Deighton ,  Mac Kidakarn

发明人： David Parker ,  Kevin Deighton ,  Mac Kidakarn

IPC分类号： F21V21/08

CPC分类号： F21V23/0414 ,  F21L4/00 ,  F21L4/027 ,  F21L4/045 ,  F21V21/0885 ,  F21V21/0965 ,  F21W2131/3005 ,  F21Y2115/10

摘要： A portable light intended for mounting on a garment as support includes two LED light sources spaced apart towards the rear of the portable light. A clipped base below on anchor facilitates locating a garment between the anchor and the base, and a spring action urges the base toward the anchor. A hingedly movable head for the LEDs is mounted on the housing to move to and form the housing. An opening of the housing causes a switch in the housing to move between an opened and closed position such that a circuit actives or de activates the LED lights when the head opens or closes relative to the housing.

公开(公告)号：US20050226242A1

公开(公告)日：2005-10-13

申请号：US10835598

申请日：2004-04-28

申请人： David Parker

发明人： David Parker

IPC分类号： H04L12/56

CPC分类号： H04L12/56 ,  H04L45/7453 ,  H04L47/2441

摘要： A pipelined packet processor is described having at least one pipeline, the at least one pipeline having one or more processing slots. Packets are assigned to available ones of the slots, and each of one or more of the assigned packets are processed during one or more cycles of processing. Upon or after a packet has undergone one or more cycles of processing, a packet classification or filtering decision is derived for the packet.

摘要翻译： 描述了流水线分组处理器具有至少一个流水线，该至少一个流水线具有一个或多个处理槽。 分组被分配给可用的时隙，并且一个或多个所分配的分组中的每一个在一个或多个处理周期期间被处理。 在分组经过一个或多个处理周期之后或之后，为分组导出分组分类或过滤决定。

公开(公告)号：US20050220094A1

公开(公告)日：2005-10-06

申请号：US10814727

申请日：2004-03-30

申请人： David Parker ,  Erik Swenson ,  Christopher Young

发明人： David Parker ,  Erik Swenson ,  Christopher Young

IPC分类号： H04L12/28 ,  H04L29/06

CPC分类号： H04L63/101 ,  H04L69/12

摘要： A command instruction set for a packet data modification processor has a format in which a packet address, if present, specifies an encapsulated layer within the packet and a location within this encapsulated layer. The at least one command within the command instruction set specifies deriving at least a portion of a first packet from data taken from a second packet or the command.

摘要翻译： 用于分组数据修改处理器的命令指令集具有其中分组地址（如果存在）指定分组内的封装层和该封装层内的位置的格式。 命令指令集中的至少一个命令指定从从第二数据包或命令获得的数据中导出第一数据包的至少一部分。