ZWITTERION SURFACE MODIFICATIONS FOR CONTINUOUS SENSORS

    公开(公告)号:US20210361205A1

    公开(公告)日:2021-11-25

    申请号:US17394690

    申请日:2021-08-05

    Applicant: DexCom, Inc.

    Abstract: Devices are provided for measurement of an analyte concentration, e.g., glucose in a host. The device can include a sensor configured to generate a signal associated with a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises a diffusion resistance domain configured to control a flux of the analyte therethrough. The diffusion resistance domain comprises one or more zwitterionic compounds and a base polymer comprising both hydrophilic and hydrophobic regions.

    Zwitterion surface modifications for continuous sensors

    公开(公告)号:US09936909B2

    公开(公告)日:2018-04-10

    申请号:US15458817

    申请日:2017-03-14

    Applicant: DexCom, Inc.

    CPC classification number: A61B5/14865 A61B5/14532 A61B5/14546 A61B5/1486

    Abstract: Devices are provided for measurement of an analyte concentration, e.g., glucose in a host. The device can include a sensor configured to generate a signal associated with a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises a diffusion resistance domain configured to control a flux of the analyte therethrough. The diffusion resistance domain comprises one or more zwitterionic compounds and a base polymer comprising both hydrophilic and hydrophobic regions.

    MEMBRANE FOR CONTINUOUS ANALYTE SENSORS
    49.
    发明申请
    MEMBRANE FOR CONTINUOUS ANALYTE SENSORS 有权
    连续分析仪传感器膜

    公开(公告)号:US20140275896A1

    公开(公告)日:2014-09-18

    申请号:US13836530

    申请日:2013-03-15

    Applicant: DexCom, Inc.

    CPC classification number: A61B5/14865 A61B5/14532 A61B5/14546

    Abstract: Devices are presented for measurement of an analyte concentration. The devices comprise: a sensor configured to generate a signal indicative of a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme domain comprising an enzyme, a base polymer, and a hydrophilic polymer which makes up from about 5 wt. % to about 30 wt. % of the enzyme domain.

    Abstract translation: 用于测量分析物浓度的装置。 所述装置包括:传感器,被配置为产生指示分析物浓度的信号; 以及位于传感器上方的感测膜。 感测膜包括酶结构域,其包含酶,基础聚合物和亲水性聚合物,其由约5wt。 %至约30wt。 %的酶结构域。

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