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51 条记录 (耗时 0.033 秒)

    DOWNHOLE ACTIVATION SYSTEM USING MAGNETS AND METHOD THEREOF
    41.
    发明申请
    DOWNHOLE ACTIVATION SYSTEM USING MAGNETS AND METHOD THEREOF 审中-公开
    使用磁铁的井下活动系统及其方法

    公开(公告)号：US20140338924A1

    公开(公告)日：2014-11-20

    申请号：US14449374

    申请日：2014-08-01

    申请人： Kenneth Wilson

    发明人： Kenneth Wilson

    IPC分类号： E21B23/00

    CPC分类号： E21B23/00 ,  E21B4/00 ,  E21B34/066 ,  E21B34/102 ,  E21B41/00

    摘要： A downhole activation system within a tubular. The system includes an axially movable member; a first magnetic field source having a first field with a first axial orientation movable with the member. A second magnetic field source having a second field with an axial orientation different from the first orientation and separated from the first magnetic field source. The second field being magnetically repulsed by the first field; and, a biasing device urging the second magnetic field source towards the first magnetic field source; wherein movement of the first magnet via the member towards the second magnet moves the second magnet in a direction against the biasing device. A method of activating an activatable member in a downhole tubular.

    摘要翻译： 管内的井下活化系统。 该系统包括一个可轴向移动的构件; 第一磁场源具有第一场，其具有可与构件一起移动的第一轴向取向。 第二磁场源，其具有轴向取向不同于第一取向并与第一磁场源分离的第二场。 第二场由第一场磁力排斥; 以及施加所述第二磁场源朝向所述第一磁场源的偏置装置; 其中所述第一磁体经由所述构件朝向所述第二磁体的移动使所述第二磁体沿着抵靠所述偏置装置的方向移动。 一种在井下管中激活可活化构件的方法。

    DOWNHOLE ACTIVATION SYSTEM USING MAGNETS AND METHOD THEREOF
    44.
    发明申请
    DOWNHOLE ACTIVATION SYSTEM USING MAGNETS AND METHOD THEREOF 有权
    使用磁铁的井下活动系统及其方法

    公开(公告)号：US20130181719A1

    公开(公告)日：2013-07-18

    申请号：US13351904

    申请日：2012-01-17

    申请人： Kenneth Wilson

    发明人： Kenneth Wilson

    IPC分类号： G01V3/08

    CPC分类号： E21B23/00 ,  E21B4/00 ,  E21B34/066 ,  E21B34/102 ,  E21B41/00

    摘要： A downhole activation system within a tubular. The system includes an axially movable mover. A first magnet attached to the mover. The first magnet axially movable with the mover. A second magnet separated from the first magnet. The second magnet magnetically repulsed by the first magnet. A biasing device urging the second magnet towards the first magnet; wherein movement of the first magnet via the mover towards the second magnet moves the second magnet in a direction against the biasing device. Also included is a method of activating an activatable member in a downhole tubular.

    摘要翻译： 管内的井下活化系统。 该系统包括可轴向移动的移动器。 附在动臂上的第一颗磁铁。 第一个磁体与动子可以轴向移动。 与第一磁体分离的第二磁体。 由第一磁铁磁力排斥的第二磁体。 朝向第一磁体推动第二磁体的偏置装置; 其中所述第一磁体经由所述动子朝向所述第二磁体的移动使所述第二磁体沿抵靠所述偏置装置的方向移动。 还包括激活井下管中的可激活构件的方法。

    Sediment retention bag
    45.
    发明申请
    Sediment retention bag 审中-公开

    公开(公告)号：US20130098817A1

    公开(公告)日：2013-04-25

    申请号：US13317683

    申请日：2011-10-25

    申请人： Kenneth Wilson

    发明人： Kenneth Wilson

    IPC分类号： B01D35/02 ,  C02F1/52 ,  C02F1/28 ,  B01D29/11

    CPC分类号： E02B3/023 ,  C02F1/286 ,  C02F1/52 ,  C02F1/5263 ,  C02F1/56 ,  C02F2001/007 ,  Y02A10/28

    摘要： A sediment retention device including a water-permeable outer containment structure, a water-impermeable injection tube including an outlet disposed within the outer containment structure, and a flocculent treatment material disposed within the injection tube. The injection tube can include an agitation structure to promote mixing contaminated water with the treatment material. A baffle including water distribution openings can be disposed over the outlet to distribute water into the outer containment structure.

    Inhibitors of C-FMS kinase
    46.
    发明授权
    Inhibitors of C-FMS kinase 有权
    C-FMS激酶抑制剂

    公开(公告)号：US07973035B2

    公开(公告)日：2011-07-05

    申请号：US12139876

    申请日：2008-06-16

    申请人： Carl R. Illig ,  Shelley K. Ballentine ,  Jinsheng Chen ,  Renee Louise DesJarlais ,  Sanath K. Meegalla ,  Mark Wall ,  Kenneth Wilson

    发明人： Carl R. Illig ,  Shelley K. Ballentine ,  Jinsheng Chen ,  Renee Louise DesJarlais ,  Sanath K. Meegalla ,  Mark Wall ,  Kenneth Wilson

    IPC分类号： A61K31/54 ,  A61K31/505 ,  C07D285/16 ,  C07D239/02

    CPC分类号： C07D403/12 ,  C07D401/12 ,  C07D401/14 ,  C07D403/14 ,  C07D405/12 ,  C07D405/14 ,  C07D417/12 ,  C07D417/14

    摘要： The invention is directed to compounds of Formula I: wherein Z, X, J, R2 and W are set forth in the specification, as well as solvates, hydrates, tautomers and pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially c-fms kinase. Methods of treating autoimmune diseases; and diseases with an inflammatory component; treating metastasis from ovarian cancer, uterine cancer, breast cancer, prostate cancer, lung cancer, colon cancer, stomach cancer, hairy cell leukemia; and treating pain, including skeletal pain caused by tumor metastasis or osteoarthritis, or visceral, inflammatory, and neurogenic pain; as well as osteoporosis, Paget's disease, and other diseases in which bone resorption mediates morbidity including rheumatoid arthritis, and other forms of inflammatory arthritis, osteoarthritis, prosthesis failure, osteolytic sarcoma, myeloma, and tumor metastasis to bone with the compounds of Formula I, are also provided.

    摘要翻译： 本发明涉及式I化合物：其中Z，X，J，R 2和W在本说明书中列出，以及其抑制蛋白酪氨酸激酶，特别是c-型的溶剂化物，水合物，互变异构体和药学上可接受的盐， fms激酶。 治疗自身免疫性疾病的方法 和具有炎症成分的疾病; 治疗卵巢癌，子宫癌，乳腺癌，前列腺癌，肺癌，结肠癌，胃癌，毛细胞白血病的转移; 并治疗疼痛，包括由肿瘤转移或骨关节炎引起的骨骼疼痛，或内脏，炎症和神经源性疼痛; 骨质疏松症，佩吉特氏病和其他疾病，其中骨吸收介导包括类风湿性关节炎和其它形式的炎症性关节炎，骨关节炎，假体衰竭，溶骨性肉瘤，骨髓瘤和肿瘤转移至骨骼的发病率与式I化合物， 也提供。

    Inhibitors of C-FMS Kinase
    49.
    发明申请
    Inhibitors of C-FMS Kinase 有权
    C-FMS激酶抑制剂

    公开(公告)号：US20080275031A1

    公开(公告)日：2008-11-06

    申请号：US12139876

    申请日：2008-06-16

    申请人： Carl R. Illig ,  Shelley K. Ballentine ,  Jinsheng Chen ,  Renee Louise DesJarlais ,  Sanath K. Meegalla ,  Mark Wall ,  Kenneth Wilson

    发明人： Carl R. Illig ,  Shelley K. Ballentine ,  Jinsheng Chen ,  Renee Louise DesJarlais ,  Sanath K. Meegalla ,  Mark Wall ,  Kenneth Wilson

    IPC分类号： A61K31/549 ,  C07D401/12 ,  C07D285/16 ,  A61K31/506 ,  A61P35/00 ,  A61P25/00 ,  A61P37/00 ,  A61P35/04 ,  A61P9/00 ,  A61P29/00 ,  C07D239/04 ,  A61K31/454

    CPC分类号： C07D403/12 ,  C07D401/12 ,  C07D401/14 ,  C07D403/14 ,  C07D405/12 ,  C07D405/14 ,  C07D417/12 ,  C07D417/14

    摘要： The invention is directed to compounds of Formula I: wherein Z, X, J, R2 and W are set forth in the specification, as well as solvates, hydrates, tautomers and pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially c-fms kinase. Methods of treating autoimmune diseases; and diseases with an inflammatory component; treating metastasis from ovarian cancer, uterine cancer, breast cancer, prostate cancer, lung cancer, colon cancer, stomach cancer, hairy cell leukemia; and treating pain, including skeletal pain caused by tumor metastasis or osteoarthritis, or visceral, inflammatory, and neurogenic pain; as well as osteoporosis, Paget's disease, and other diseases in which bone resorption mediates morbidity including rheumatoid arthritis, and other forms of inflammatory arthritis, osteoarthritis, prosthesis failure, osteolytic sarcoma, myeloma, and tumor metastasis to bone with the compounds of Formula I, are also provided.

    摘要翻译： 本发明涉及式I化合物：其中Z，X，J，R 2和W在本说明书中列出，以及溶剂合物，水合物，互变异构体及其药学上可接受的盐，其中 抑制蛋白酪氨酸激酶，特别是c-fms激酶。 治疗自身免疫性疾病的方法 和具有炎症成分的疾病; 治疗卵巢癌，子宫癌，乳腺癌，前列腺癌，肺癌，结肠癌，胃癌，毛细胞白血病的转移; 并治疗疼痛，包括由肿瘤转移或骨关节炎引起的骨骼疼痛，或内脏，炎症和神经源性疼痛; 骨质疏松症，佩吉特氏病和其他疾病，其中骨吸收介导包括类风湿性关节炎和其它形式的炎症性关节炎，骨关节炎，假体衰竭，溶骨性肉瘤，骨髓瘤和肿瘤转移至骨骼的发病率与式I化合物， 也提供。

    Inhibitors of c-fms kinase
    50.
    发明授权
    Inhibitors of c-fms kinase 有权
    c-fms激酶抑制剂

    公开(公告)号：US07414050B2

    公开(公告)日：2008-08-19

    申请号：US11736617

    申请日：2007-04-18

    申请人： Carl R. Illig ,  Shelly K. Ballentine ,  Jinsheng Chen ,  Renee Louise DesJarlais ,  Sanath K. Meegalla ,  Mark Wall ,  Kenneth Wilson

    发明人： Carl R. Illig ,  Shelly K. Ballentine ,  Jinsheng Chen ,  Renee Louise DesJarlais ,  Sanath K. Meegalla ,  Mark Wall ,  Kenneth Wilson

    IPC分类号： C07D417/04 ,  C07D417/14 ,  A61K31/541

    CPC分类号： C07D403/12 ,  C07D401/12 ,  C07D401/14 ,  C07D403/14 ,  C07D405/12 ,  C07D405/14 ,  C07D417/12 ,  C07D417/14

    摘要： The invention is directed to compounds of Formula I: wherein Z, X, J, R2 and W are set forth in the specification, as well as solvates, hydrates, tautomers and pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially c-fms kinase. Methods of treating autoimmune diseases; and diseases with an inflammatory component; treating metastasis from ovarian cancer, uterine cancer, breast cancer, prostate cancer, lung cancer, colon cancer, stomach cancer, hairy cell leukemia; and treating pain, including skeletal pain caused by tumor metastasis or osteoarthritis, or visceral, inflammatory, and neurogenic pain; as well as osteoporosis, Paget's disease, and other diseases in which bone resorption mediates morbidity including rheumatoid arthritis, and other forms of inflammatory arthritis, osteoarthritis, prosthesis failure, osteolytic sarcoma, myeloma, and tumor metastasis to bone with the compounds of Formula I, are also provided.

    摘要翻译： 本发明涉及式I化合物：其中Z，X，J，R 2和W在本说明书中列出，以及溶剂合物，水合物，互变异构体及其药学上可接受的盐，其中 抑制蛋白酪氨酸激酶，特别是c-fms激酶。 治疗自身免疫性疾病的方法 和具有炎症成分的疾病; 治疗卵巢癌，子宫癌，乳腺癌，前列腺癌，肺癌，结肠癌，胃癌，毛细胞白血病的转移; 并治疗疼痛，包括由肿瘤转移或骨关节炎引起的骨骼疼痛，或内脏，炎症和神经源性疼痛; 骨质疏松症，佩吉特氏病和其他疾病，其中骨吸收介导包括类风湿性关节炎和其它形式的炎症性关节炎，骨关节炎，假体衰竭，溶骨性肉瘤，骨髓瘤和肿瘤转移至骨骼的发病率与式I化合物， 也提供。