公开(公告)号：US11512105B2

公开(公告)日：2022-11-29

申请号：US16840871

申请日：2020-04-06

Applicant: Samsung Electronics Co., Ltd.

Inventor： Kum Hee Lee ,  Seungyeon Kwak ,  Yoonhyun Kwak ,  Ohyun Kwon ,  Aram Jeon ,  Whail Choi ,  Kyuyoung Hwang ,  Byoungki Choi ,  Hyeonho Choi

IPC: C07F15/00 ,  H01L51/00 ,  C09K11/06 ,  C07D293/10 ,  C07D329/00 ,  C07D339/00 ,  C07D419/02

Abstract: An organometallic compound represented by Formula 1, an organic light-emitting device including the organometallic compound, and a diagnostic composition including the organometallic compound: M(L1)n1(L2)n2,  Formula 1 wherein, in Formula 1, M, L1, L2, n1, and n2 are each independently the same as described herein.

公开(公告)号：US08765934B2

公开(公告)日：2014-07-01

申请号：US13188989

申请日：2011-07-22

Applicant: Tzu-Pin Wang ,  Yi-Jhang Ciou

Inventor： Tzu-Pin Wang ,  Yi-Jhang Ciou

IPC: C07H21/00 ,  C12Q1/68 ,  C07D293/10 ,  C07D235/02

CPC classification number: C07H21/04 ,  A61K31/7105 ,  C07D495/04 ,  C07H21/02 ,  C07K1/1077

Abstract: A method for conjugating a nucleic acid with a molecule is provided. The method includes steps of (a) reacting the nucleic acid having a 5′-monophosphate with an activating agent in a first buffer to form a solution; (b) mixing an alcohol with the solution formed in the step (a) to obtain an intermediate; and (c) dissolving the intermediate in a second buffer containing an ethylenediaminetetraacetic acid (EDTA) and adding a nucleophile thereinto to react the intermediate with the nucleophile.

Abstract translation: 提供了用于将核酸与分子缀合的方法。 该方法包括以下步骤：（a）使具有5'-单磷酸的核酸与活化剂在第一缓冲液中反应形成溶液; （b）将醇与步骤（a）中形成的溶液混合以获得中间体; 和（c）将中间体溶解在含有乙二胺四乙酸（EDTA）的第二缓冲液中并加入亲核试剂以使中间体与亲核试剂反应。

公开(公告)号：US08663804B2

公开(公告)日：2014-03-04

申请号：US13168069

申请日：2011-06-24

Applicant: George Elias Zahr

Inventor： George Elias Zahr

IPC: B32B27/38 ,  C07D293/10 ,  C07D251/00 ,  C08L63/00 ,  C08K9/00

CPC classification number: H05K3/386 ,  H05K3/281 ,  H05K2203/1189 ,  Y10T428/31511

Abstract: The present invention deals with a flexible printed wiring board in the form of a printed wiring board wherein the conductive elements are fully encapsulated by an epoxy adhesive comprising a novel aromatic di-isoimide chemical compound. The conductive elements are thereby protected. The flexible printed wiring board is readily cured at a temperature in the range of 100 to 250° C. However, before curing, by virtue of the latent cure feature of the epoxy adhesive, the adhesive component of the printed wiring board has an extended shelf life, and avoids premature curing during processing.

Abstract translation: 本发明涉及印刷电路板形式的柔性印刷线路板，其中导电元件被包含新型芳族二异亚酰亚胺化合物的环氧粘合剂完全包封。 从而保护导电元件。 柔性印刷电路板容易在100-250℃的温度下固化。然而，在固化之前，通过环氧树脂粘合剂的潜固化特征，印刷电路板的粘合剂组分具有延伸架 生活，避免加工过早固化。

公开(公告)号：US08580386B2

公开(公告)日：2013-11-12

申请号：US13168062

申请日：2011-06-24

Applicant: George Elias Zahr

Inventor： George Elias Zahr

IPC: B32B27/38 ,  C08G61/02 ,  C07D251/00 ,  C08L63/00 ,  C07D293/10 ,  C08K9/00

CPC classification number: C08J7/047 ,  C08J2463/00 ,  Y10T428/269 ,  Y10T428/31511

Abstract: The present invention deals with a laminate useful for forming fully encapsulated flexible printed wiring boards. The laminate comprises a dielectric substrate coated with a curable composition comprising an epoxy and a novel aromatic di-isoimide chemical compound. The curable composition provides the benefit of thermal latency, improving shelf-life, and reducing premature curing during processing. Fully encapsulated printed wiring boards are also disclosed.

Abstract translation: 本发明涉及用于形成完全封装的柔性印刷线路板的层压板。 层压体包括涂覆有包含环氧树脂和新型芳族二异亚酰亚胺化合物的可固化组合物的电介质基材。 可固化组合物提供热潜伏期的益处，改善保存期限，并减少加工过程中的过早固化。 还公开了完全封装的印刷线路板。

公开(公告)号：US07744672B2

公开(公告)日：2010-06-29

申请号：US11719674

申请日：2005-11-17

Applicant: Sergey Mikhailovich Kononov ,  Anatoliy Nikolaevich Avramenko ,  Oleg Anatolievich Shirobokov ,  Victor Nikolaevich Gromotkov ,  Victor Filippovich Perepechko ,  Victor Alekseevich Tzarevskiy ,  Igor Andreevich Mitzak ,  Vyacheslav Mikhailovich Ovchinnikov ,  Stanislava Stanislavovna Kostuchenko ,  Evdokiya Nikolaevna Kontareva

Inventor： Sergey Mikhailovich Kononov ,  Anatoliy Nikolaevich Avramenko ,  Oleg Anatolievich Shirobokov ,  Victor Nikolaevich Gromotkov ,  Victor Filippovich Perepechko ,  Victor Alekseevich Tzarevskiy ,  Igor Andreevich Mitzak ,  Vyacheslav Mikhailovich Ovchinnikov ,  Stanislava Stanislavovna Kostuchenko ,  Evdokiya Nikolaevna Kontareva

IPC: C05D9/02 ,  C07D293/10

CPC classification number: C05C1/02 ,  C05D1/02

Abstract: The invention relates to the chemical industry and can be used while producing granulated nitrogen-potash fertilizers. An ammonia nitrate melt in the amount of 33-69 weight %, potassium chloride in the amount of 22-65 weight %, and a specific mineral admixture—phosphogypsum in the amount of 2-9 weight % are fed into a mixture as well as ammonia, which is necessary for keeping pH value of the mixture within the range of 6.5-7.5. The obtained slurry is sprayed onto a recycle product in a drum granulator and granulated under a recycle ratio being equal to 1:(2-2.5), the final product is dried. A stirring is carried out under the optimal operational mode within the temperature range of 100-130° C. during 20-30 minutes. Due to such conditions, a productivity rate of the process is increased and granules of the fertilizer have higher strength and reduced leachability from the soil.

Abstract translation: 本发明涉及化学工业，可用于生产粒状氮钾肥。 将33-69重量％的氨氮熔体，22-65重量％的氯化钾和2-9重量％的特定矿物掺合物 - 磷石膏加入混合物中， 氨，这是将混合物的pH值保持在6.5-7.5的范围内所必需的。 将获得的浆料在鼓式造粒机中喷射到再循环产物上，并以等于1（2-2.5）的循环比造粒，将最终产物干燥。 在100〜130℃的温度范围内，在20-30分钟内，在最佳操作模式下进行搅拌。 由于这样的条件，该方法的生产率提高，并且肥料颗粒具有较高的强度和降低了从土壤的浸出性。

公开(公告)号：US07301028B2

公开(公告)日：2007-11-27

申请号：US10517576

申请日：2003-06-12

Applicant: Kenneth L. Arrington ,  Mark E. Fraley

Inventor： Kenneth L. Arrington ,  Mark E. Fraley

IPC: C07D401/02 ,  C07D293/10 ,  C07D291/00 ,  C07D265/00 ,  C07D257/12 ,  C07D251/00 ,  C07D213/00 ,  C07D221/02 ,  C07D211/00 ,  C07D421/00 ,  C07D271/00 ,  C07D277/04 ,  C07D513/00 ,  A01N43/00 ,  A01N43/62 ,  A01N43/66 ,  A01N43/58 ,  A01N43/40 ,  A01N43/64 ,  A61K31/54 ,  A61K31/535 ,  A61K31/40

CPC classification number: C07D207/27 ,  C07D207/20

Abstract: The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.

Abstract translation: 本发明涉及可用于治疗细胞增殖性疾病，治疗与KSP驱动蛋白活性相关的疾病和用于抑制KSP驱动蛋白的二氢吡唑化合物。 本发明还涉及包含这些化合物的组合物，以及使用它们治疗哺乳动物癌症的方法。

公开(公告)号：US20070123501A1

公开(公告)日：2007-05-31

申请号：US11543994

申请日：2006-10-06

Applicant: Dusan Kuzma ,  Thomas Back ,  Noah Berkowitz

Inventor： Dusan Kuzma ,  Thomas Back ,  Noah Berkowitz

IPC: C07D293/10 ,  C07D345/00 ,  A61K31/33

CPC classification number: C07D345/00 ,  C07D329/00 ,  C07D517/10

Abstract: This invention relates to novel organoselenium and tellurium compounds, processes of producing the same and methods of use thereof. The compounds function as mimetics for the catalyst selenoenzyme glutathione peroxidase, which protects cells from oxidative stress.

Abstract translation: 本发明涉及新型有机硒和碲化合物，其制备方法及其使用方法。 该化合物作为催化剂硒酶酶谷胱甘肽过氧化物酶的模拟物，其保护细胞免受氧化应激。

公开(公告)号：US20060135569A1

公开(公告)日：2006-06-22

申请号：US10518647

申请日：2003-06-19

Applicant: Xiaoliang Wang ,  Zongru Guo ,  Jing Lu ,  Fengming Chu ,  Yaping Pan ,  Ling Wang

Inventor： Xiaoliang Wang ,  Zongru Guo ,  Jing Lu ,  Fengming Chu ,  Yaping Pan ,  Ling Wang

IPC: A61K31/41 ,  C07D293/10

CPC classification number: A61K31/41

Abstract: The invention discloses use of benzisoselenazolones, particularly compounds represented by the general formula (I) against ischemic myocardial injury. The compounds are characterized by selectively inhibiting Na+/Ca2+ exchange, dilating coronary artery and decreasing myocardial oxygen consumption, which possess the advantages of high activity, potent specificity and low toxicity.

Abstract translation: 本发明公开了苯并异恶唑啉酮，特别是通式（I）表示的化合物对缺血性心肌损伤的应用。 该化合物的特征在于选择性抑制Na + / ATP 2 +交换，扩张冠状动脉和降低心肌耗氧量，其具有高活性，有效特异性和低 毒性。

公开(公告)号：US20030165711A1

公开(公告)日：2003-09-04

申请号：US09992409

申请日：2001-11-26

Inventor： Youngkyoo Kim ,  Jae-Gyoung Lee

IPC: H05B033/14 ,  C07D235/04 ,  C07D263/54 ,  C07D293/10

CPC classification number: H01L51/0077 ,  C07D215/36 ,  H01L51/0034 ,  H01L51/0035 ,  H01L51/0059 ,  H01L51/0089 ,  H01L51/5012 ,  Y10S428/917

Abstract: An organometallic luminescent material comprising the compound of formula (I) of the present invention can emit pure blue light and have high thermal stability: 1 wherein, M1 is a monovalent or tetravalent metal selected from the group consisting of Li, Na, K, Zr, Si, Ti, Sn, Cs, Fr, Rb, Hf, Pr, Pa, Ge, Pb, Tm and Md; R is hydrogen or C1-10 alkyl; B is O, S, Se or Te; D is O or S; and n is an integer ranging from 1 to 4.

Abstract translation: 包含本发明式（I）化合物的有机金属发光材料可以发出纯蓝光并具有高热稳定性：其中，M1是选自Li，Na，K，Zr等的一价或四价金属， Si，Ti，Sn，Cs，Fr，Rb，Hf，Pr，Pa，Ge，Pb，Tm和Md; R是氢或C 1-10烷基; B是O，S，Se或Te; D为O或S; n为1〜4的整数。

公开(公告)号：US6130212A

公开(公告)日：2000-10-10

申请号：US329755

申请日：1999-06-10

Applicant: Jinzhu Xu ,  Georges Appere ,  Jean Chaudiere ,  Jean-Claude Yadan

Inventor： Jinzhu Xu ,  Georges Appere ,  Jean Chaudiere ,  Jean-Claude Yadan

IPC: A61K33/04 ,  C07D293/10 ,  C07D293/12 ,  C07J51/00 ,  A61K31/58 ,  A61K31/395 ,  A61K31/41

CPC classification number: C07D293/12 ,  C07D293/10 ,  C07J51/00

Abstract: Compounds represented by the following formula I: ##STR1## in which: R.sup.1 to R.sup.5 can have various meanings of which alkyl, substituted or non-substituted aryl, and m is equal to 0 or 1, X is selected from (CR.sup.6 R.sup.7).sub.n in which n=0 or 1, and CO are disclosed. These compounds are useful as anti-tumor drugs, especially with pro-oxidizing activity.

Abstract translation: 由下式I表示的化合物：其中：R 1至R 5可以具有其中烷基，取代或未取代的芳基，m等于0或1的各种含义，X选自（​​CR 6 R 7）n，其中n = 0或1，并公开CO。 这些化合物可用作抗肿瘤药物，特别是具有促氧化活性。