利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

110 条记录 (耗时 0.028 秒)

    DNA molecules encoding human nuclear receptor proteins
    41.
    发明授权
    DNA molecules encoding human nuclear receptor proteins 失效

    公开(公告)号：US6054295A

    公开(公告)日：2000-04-25

    申请号：US141000

    申请日：1998-08-26

    申请人： Fang Chen

    发明人： Fang Chen

    IPC分类号： C07K14/705 ,  C12N15/12 ,  C12N5/10 ,  C12N15/63

    CPC分类号： C07K14/70567

    摘要： The present invention discloses the isolation and characterization of cDNA molecules encoding two human nuclear receptor proteins, designated nNR1, nNR2 and/or nNR2-1. Also within the scope of the disclosure are recombinant vectors, recombinant host cells, methods of screening for modulators of nNR1, nNR2 and/or nNR2-1 activity, and production of antibodies against nNR1, nNR2 and/or nNR2-1, or epitopes thereof.

    Apparatus and method for measuring contact force distribution of a tire
    42.
    发明授权
    Apparatus and method for measuring contact force distribution of a tire 失效
    用于测量轮胎的接触力分布的装置和方法

    公开(公告)号：US5616839A

    公开(公告)日：1997-04-01

    申请号：US593762

    申请日：1996-01-29

    申请人： Fang Chen ,  Christopher T. Griffen ,  Eel-Jeu Ni

    发明人： Fang Chen ,  Christopher T. Griffen ,  Eel-Jeu Ni

    IPC分类号： G01M17/02

    CPC分类号： G01M17/027

    摘要： An apparatus and method for measuring full-field contact force distribution of a tire. A transparent, elastically deformable contact member having an elasticity substantially less than the elasticity of the tire is supported by a transparent rigid support member. As the tire is pressed into the contact member, the contact member deforms. Laser light illuminates the tire-contact member interface and is reflected to an imaging device which measures the displacement of the tire-contact member interface using interferometry principles. Because the elasticity of the contact member is known, the contact force distribution of the tire may be calculated. The apparatus and method may also be used to measure three-dimensional as well as dynamic contact force displacement.

    摘要翻译： 一种用于测量轮胎的全场接触力分布的装置和方法。 具有基本上小于轮胎弹性的弹性的透明的可弹性变形的接触构件由透明刚性支撑构件支撑。 当轮胎被压入接触构件时，接触构件变形。 激光照亮轮胎 - 接触构件界面并被反射到成像装置，该成像装置使用干涉测量原理测量轮胎 - 接触构件界面的位移。 因为接触构件的弹性是已知的，所以可以计算轮胎的接触力分布。 该装置和方法也可用于测量三维以及动态接触力位移。

    Interlocking Work Platform System and Method
    44.
    发明申请
    Interlocking Work Platform System and Method 有权

    公开(公告)号：US20220282501A1

    公开(公告)日：2022-09-08

    申请号：US17681076

    申请日：2022-02-25

    申请人： Fang Chen ,  Liang He ,  Ling Zhu

    发明人： Fang Chen ,  Liang He ,  Ling Zhu

    IPC分类号： E04G1/30 ,  E06C1/393

    摘要： A work platform system having a first work platform. The first work platform having a first hook assembly and a first latch assembly. The system having a second work platform. The second work platform having a second hook assembly and a second latch assembly. The first work platform locked to the second work platform through the first hook assembly engaging with the second latch assembly and the first hook assembly in the use position. A method for using a work platform system. A method for producing a work platform.

    Method and system for providing a highly-personalized recommendation engine
    45.
    发明授权
    Method and system for providing a highly-personalized recommendation engine 有权

    公开(公告)号：US10956523B2

    公开(公告)日：2021-03-23

    申请号：US16129453

    申请日：2018-09-12

    申请人： Yu Huang ,  Fang Chen

    发明人： Yu Huang ,  Fang Chen

    IPC分类号： G06F16/9535 ,  G06K9/00 ,  G06N3/08 ,  G06F16/51 ,  G06F16/583 ,  G06K9/62

    摘要： Various embodiments of a deep learning (DL)-based face perception engine for constructing, providing, and applying a highly-personalized face perception model for an individual through a deep learning process are disclosed. In some embodiments, a disclosed face perception engine includes a deep neural network configured for training a personalized face perception model for a unique individual based on a standard set of training images and a corresponding set of decisions on the set of training images provided by the unique individual. When sufficiently trained using the standard set of training images and the corresponding set of decisions, the personalized face perception model for the unique individual perceives a new face photo/image as if through the eyes of that unique individual. Hence, the trained face perception model can be used an “agent” or “representative” of the associated person in making very personal decisions, such as to decide if a given face photo/image includes a desirable face in the eyes of that person.

    No Popping-off and No Bunching-up Simple Bedding System
    46.
    发明申请
    No Popping-off and No Bunching-up Simple Bedding System 审中-公开

    公开(公告)号：US20200260886A1

    公开(公告)日：2020-08-20

    申请号：US16278142

    申请日：2019-02-17

    申请人： Fang Chen

    发明人： Fang Chen

    IPC分类号： A47G9/04 ,  A47G9/02

    摘要： A bedding system termed “No Hassle Bedding System” is disclosed to solve the issues of mattress pad and/or fitted/bottom sheet popping off a mattress, lifting mattress to put on a mattress pad and/or fitted/bottom sheet, and flat/top sheet bunching up in a simple and economical way. The system consists of a strap system that is built-in on a mattress or in a mattress-free form, matching flat mattress pad and flat bottom sheet that can be secured onto a mattress, a flat/top sheet with built-in ribbons and a blanket/comforter/duvet/quilt/etc with built-in loops so that they can be assembled and disassembled easily.

    LED illumination device and validation methodology of LED illumination device's lifespan
    48.
    发明授权
    LED illumination device and validation methodology of LED illumination device's lifespan 有权
    LED照明装置及LED照明装置使用寿命的验证方法

    公开(公告)号：US08975818B2

    公开(公告)日：2015-03-10

    申请号：US14130928

    申请日：2012-07-19

    申请人： Fang Chen ,  Yehua Wan ,  Jinxiang Shen

    发明人： Fang Chen ,  Yehua Wan ,  Jinxiang Shen

    IPC分类号： H05B33/08 ,  G01J1/42 ,  F21V3/00 ,  F21V23/00 ,  F21V23/04 ,  F21Y101/02

    CPC分类号： H05B33/0884 ,  F21V3/00 ,  F21V23/003 ,  F21V23/004 ,  F21V23/0464 ,  F21Y2115/10 ,  G01J1/42 ,  G01J2001/4247 ,  H05B33/0803 ,  H05B33/0893 ,  Y02B20/42

    摘要： A LED illumination device and validation methodology of LED illumination device's lifespan, comprises a controller, timing chip and low-voltage DC power supply, the controller is connected to the display terminal, the timing chip is positioned inside the LED illumination device, so as to get real-time recording of the operating time of the LED illumination device which is transmitted to the display terminal for display; meanwhile, a light sensor is placed in the luminous zone to obtain luminosity data so as to measure real-time luminous maintenance rate. When the measured luminous maintenance rate gets lower than the luminous maintenance rate predetermined for critical lifespan, the operating time recorded by the LED illumination device at this moment is the lifespan of this LED illumination device.

    摘要翻译： LED照明装置和LED照明装置寿命的验证方法包括控制器，定时芯片和低压直流电源，控制器连接到显示终端，定时芯片位于LED照明装置的内部，以便 实时记录发送到显示终端进行显示的LED照明装置的工作时间; 同时，将光传感器放置在发光区域以获得亮度数据，以便测量实时的发光维持率。 当测量的发光维持率低于关键寿命预定的发光维持率时，此时由LED照明装置记录的工作时间是该LED照明装置的寿命。

    METHOD AND SYSTEM FOR DETERMINING COPY NUMBER VARIATION
    49.
    发明申请
    METHOD AND SYSTEM FOR DETERMINING COPY NUMBER VARIATION 审中-公开
    用于确定复制数变化的方法和系统

    公开(公告)号：US20150056619A1

    公开(公告)日：2015-02-26

    申请号：US14389898

    申请日：2012-04-05

    申请人： Xuchao Li ,  Shengpei Chen ,  Fang Chen ,  Weiwei Xie ,  Jian Wang ,  Jun Wang ,  Huanming Yang ,  Xiuqing Zhang

    发明人： Xuchao Li ,  Shengpei Chen ,  Fang Chen ,  Weiwei Xie ,  Jian Wang ,  Jun Wang ,  Huanming Yang ,  Xiuqing Zhang

    IPC分类号： C12Q1/68

    CPC分类号： C12Q1/68 ,  C12Q1/6869 ,  C12Q2535/122 ,  C12Q2537/165 ,  G16B15/00 ,  G16B30/00 ,  G16C99/00

    摘要： Disclosed are a method and a system for determining genome copy number variation, which relates to the technical field of bioinformatics. The method comprises obtaining reads; determining sequence labels according to the reads; counting the number of sequence labels falling into each window; performing GC correction on the sequence label number of each window and a correction according to an expected sequence label number adjusted by a control set to obtain a corrected sequence label number; selecting a demarcation point with a small significance value as a candidate CNV breaking point; rejecting the least significant candidate CNV breaking point at every turn, updating difference significance values of two candidate CNV breaking points on the left and right of the rejected candidate CNV breaking point and performing cyclic iteration until difference significance values of all candidate CNV breaking points are smaller than a termination threshold value, thereby determining a CNV breaking point. The method and the system the present invention have clinical feasibility, and can precisely detect a micro-deletion/micro-duplication area of 0.5 M under the situation of using data of about 50 M.

    摘要翻译： 公开了用于确定与生物信息学技术领域有关的基因组拷贝数变异的方法和系统。 该方法包括获取读数; 根据读数确定序列标签; 计算落入每个窗口的序列标签的数量; 对每个窗口的序列标签号执行GC校正，并根据由控制集调整的预期序列标号进行校正，以获得校正的序列标号; 选择具有较小重要性值的分界点作为候选CNV断点; 拒绝每一回合中最不重要的候选CNV断点，更新拒绝的候选CNV断点左侧和右侧的两个候选CNV断点的差异有效值，并执行循环迭代，直到所有候选CNV断点的差值显着值较小 比终止阈值，从而确定CNV断点。 本发明的方法和系统具有临床可行性，并且可以在使用约50M的数据的情况下精确地检测到0.5M的微缺失/微复制区域。