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公开(公告)号：US11172868B2
公开(公告)日：2021-11-16
申请号：US16041084
申请日：2018-07-20
Applicant: Yi Zheng , Anna Zheng , Qi Wu , Hui Jiang , Shun Zhang , Weining Hu
Inventor： Yi Zheng , Anna Zheng , Qi Wu , Hui Jiang , Shun Zhang , Weining Hu
Abstract: A system and method to screen for malignant gliomas, other brain tumors, and brain injuries use disturbance coefficient, differential impedances, and artificial neural networks. The system uses prescribed excitation signals with several system configurations to measure the differential impedances, calculate harmonic responses and nonlinearity of brain tissue, and estimate the disturbance coefficient that indicates the likelihood of malignant gliomas, other brain tumors, and brain injuries. The disturbance coefficient is a weighted sum of many parameters such as receiving differential impedances, transmission differential impedances, harmonic responses, frequency dispersion, and nonlinear responses using different system configurations and different excitation signals. The method includes arranging the transmitters, receivers, and transmission lines to maximize the sensitivity of detecting brain tissue condition. The artificial neural network is trained to estimate the disturbance coefficient using clinical data. The method provides a sensitive and cost effective approach for screening malignant gliomas, other brain tumors, and brain injuries.
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公开(公告)号：US20190021647A1
公开(公告)日：2019-01-24
申请号：US16041084
申请日：2018-07-20
Applicant: Yi Zheng , Anna Zheng , Qi Wu , Hui Jiang , Shun Zhang , Weining Hu
Inventor： Yi Zheng , Anna Zheng , Qi Wu , Hui Jiang , Shun Zhang , Weining Hu
Abstract: A system and method to screen for malignant gliomas, other brain tumors, and brain injuries use disturbance coefficient, differential impedances, and artificial neural networks. The system uses prescribed excitation signals with several system configurations to measure the differential impedances, calculate harmonic responses and nonlinearity of brain tissue, and estimate the disturbance coefficient that indicates the likelihood of malignant gliomas, other brain tumors, and brain injuries. The disturbance coefficient is a weighted sum of many parameters such as receiving differential impedances, transmission differential impedances, harmonic responses, frequency dispersion, and nonlinear responses using different system configurations and different excitation signals. The method includes arranging the transmitters, receivers, and transmission lines to maximize the sensitivity of detecting brain tissue condition. The artificial neural network is trained to estimate the disturbance coefficient using clinical data. The method provides a sensitive and cost effective approach for screening malignant gliomas, other brain tumors, and brain injuries.
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公开(公告)号：US09734824B2
公开(公告)日：2017-08-15
申请号：US14720891
申请日：2015-05-25
Applicant: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO , Hui Jiang , Ossama Abdelhamid Mohamed Abdelhamid
Inventor： Gerald Bradley Penn , Hui Jiang , Ossama Abdelhamid Mohamed Abdelhamid , Abdel-rahman Samir Abdel-rahman Mohamed
Abstract: A system and method for applying a convolutional neural network (CNN) to speech recognition. The CNN may provide input to a hidden Markov model and has at least one pair of a convolution layer and a pooling layer. The CNN operates along the frequency axis. The CNN has units that operate upon one or more local frequency bands of an acoustic signal. The CNN mitigates acoustic variation.
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公开(公告)号：US09651662B2
公开(公告)日：2017-05-16
申请号：US12742255
申请日：2008-11-13
Applicant: Jochen Kruecker , Sheng Xu , Hui Jiang
Inventor： Jochen Kruecker , Sheng Xu , Hui Jiang
CPC classification number: G01S15/899 , A61B8/0833 , A61B8/4245 , A61B8/4263 , G01S7/52074 , G01S7/52098 , G01S15/8993
Abstract: A method for interventional navigation using 3D contrast-enhanced ultrasound (CEUS) imaging includes acquiring a reference 3D CEUS volume and tracking information during a useful lifetime of a contrast enhancement agent administered to the anatomy. Real-time tracked tissue images are acquired during the interventional procedure. In addition, a corresponding CEUS multiplanar reconstruction (MPR) for at least one of the acquired real-time tracked tissue images is generated. At least one of the acquired real-time tracked tissue images is displayed along with the corresponding CEUS MPR. The displayed real-time tracked tissue image includes at least an image of the instrument within the desired portion of the anatomy and the CEUS MPR corresponds to the displayed real-time tracked tissue image. Thus, the contrast enhanced image information and tissue image information are concurrently display for the interventional navigation at least subsequent to the expiration of the contrast enhancement useful lifetime.
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Patent Agency Ranking
公开(公告)号：US09215246B2
公开(公告)日：2015-12-15
申请号：US13878955
申请日：2011-10-21
Applicant: Da Zhou , Xiaoming Wang , Ming Lv , Hui Jiang , Guangxu Liu , Xiaohai Lu , Na Li , Xing Ye
Inventor： Da Zhou , Xiaoming Wang , Ming Lv , Hui Jiang , Guangxu Liu , Xiaohai Lu , Na Li , Xing Ye
CPC classification number: H04L63/1433 , G06F21/577 , G06F21/6209 , G06F2221/2119 , H04L63/1483 , H04L63/168 , H04L67/02
Abstract: The invention discloses a website scanning apparatus for performing a security vulnerability scanning on a target website, which apparatus comprises: a web page obtaining component obtaining current content and/or features of a web page corresponding to a link to be processed; a link processing component including a change judgment device for judging whether the web page corresponding to the link to be processed has been changed based on stored web page content and/or features corresponding to the link to be processed as well as the current web page content and/or features of the link to be processed; and a vulnerability detecting component for performing a security vulnerability detection on a web page corresponding to a link to be processed for which the web page has been changed. The invention also discloses a website scanning method corresponding thereto.
Abstract translation: 本发明公开了一种用于在目标网站上执行安全漏洞扫描的网站扫描装置，该装置包括：获取与要处理的链接相对应的网页的当前内容和/或特征的网页获取组件; 一种链接处理部件，包括：变更判断装置，用于基于所存储的网页内容和/或与要处理的链接相对应的特征以及当前网页内容来判断与要处理的链接相对应的网页是否已被改变 和/或要处理的链接的特征; 以及漏洞检测组件，用于在与要处理的链接相对应的网页上执行安全漏洞检测，网页已被改变。 本发明还公开了一种与其对应的网站扫描方法。
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公开(公告)号：US09133513B2
公开(公告)日：2015-09-15
申请号：US14119266
申请日：2012-05-22
Applicant: Huijuan Luo , Guanyu Ji , Hui Jiang , Mingzhi Wu , Jihua Sun , Renhua Wu , Junwen Wang , Fei Gao
Inventor： Huijuan Luo , Guanyu Ji , Hui Jiang , Mingzhi Wu , Jihua Sun , Renhua Wu , Junwen Wang , Fei Gao
CPC classification number: C12Q1/6874 , C12N15/1065 , C12Q1/6806 , C12Q1/6869 , C40B50/06 , C12Q2523/125 , C12Q2525/191 , C12Q2535/122 , C12Q2537/159
Abstract: Provided is a high throughput methylation detection method, particularly a combined sequence capture and bisulfite sequencing method. The method accurately and effectively analyzes the methylation status of the target area in several samples simultaneously, lowers the difficulty of probe design, enhances operation and application feasibility, and enables high throughput methylation detection of high accuracy on interested target sequences and areas in a complete genome. The method is targeted and conserves energy and time.
Abstract translation: 提供了高通量甲基化检测方法，特别是组合的序列捕获和亚硫酸氢盐测序方法。 该方法同时精确有效地分析了几个样本中目标区域的甲基化状态，降低了探针设计的难度，提高了操作和应用的可行性，并且使得在完整基因组中有兴趣的靶序列和区域具有高准确度的高通量甲基化检测 。 该方法是针对性的，节约能源和时间。
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公开(公告)号：US09099784B2
公开(公告)日：2015-08-04
申请号：US13976700
申请日：2011-06-13
CPC classification number: H01Q1/50 , H01Q1/243 , H01Q9/0407 , H01Q9/0414 , H01Q21/28 , H01Q21/29 , Y10T29/49016
Abstract: An antenna array of a mobile terminal and an implementing method thereof are disclosed in this document. The antenna array includes: a mobile terminal floorboard, configured to act as a radiation body to radiate antenna energy coupled by multiple pairs of coupling units, and multiple pairs of coupling units corresponding to multiple antennas, each of which are fixed at two ends of the mobile terminal floorboard and are configured to inspire a waveguide mode of the mobile terminal floorboard to radiate the coupled antenna energy through feed points of feed lines of each coupling unit therein, located at the same side of a dielectric material plate; and a matching circuit located at the other side of the dielectric material plate, connected with the feed points located at the opposite side of the dielectric material plate and configured to implement impedance matching of a micro-strip feed line of each coupling unit.
Abstract translation: 本文中公开了移动终端的天线阵列及其实现方法。 天线阵列包括：移动终端地板块，其被配置为充当辐射体以辐射由多对耦合单元耦合的天线能量，以及对应于多个天线的多对耦合单元，每对耦合单元固定在 配置为启动移动终端地板块的波导模式，以通过位于介电材料板的同一侧的每个耦合单元的馈送线的馈送点辐射耦合的天线能量; 以及匹配电路，位于电介质材料板的另一侧，与位于电介质材料板的相对侧的馈电点相连，并被配置为实现每个耦合单元的微带馈电线的阻抗匹配。
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9.发明申请METHOD AND SYSTEM FOR DETERMINING WHETHER COPY NUMBER VARIATION EXISTS IN SAMPLE GENOME, AND COMPUTER READABLE MEDIUM 审中-公开用于确定样品基因组中复制数量变化现象的方法和系统以及计算机可读介质公开(公告)号：US20150012252A1
公开(公告)日：2015-01-08
申请号：US14373072
申请日：2012-01-20
Applicant: Xuyang Yin , Chunlei Zhang , Shengpei Chen , Chunsheng Zhang , Xiaoyu Pan , Hui Jiang , Xiuqing Zhang
Inventor： Xuyang Yin , Chunlei Zhang , Shengpei Chen , Chunsheng Zhang , Xiaoyu Pan , Hui Jiang , Xiuqing Zhang
CPC classification number: G16B5/00 , C12Q1/6809 , G06F17/5009 , G16B30/00 , C12Q2535/122 , C12Q2537/16 , C12Q2537/165
Abstract: Provided are a method, system, and computer-readable medium for determining whether a copy number variation exists in a sample genome. The method includes sequencing a sample genome to obtain a sequencing result formed by multiple reads; comparing the sequencing result with a reference genome sequence to determine the distribution of the reads on the reference genome sequence; determining, based on the distribution of the reads on the reference genome sequence, multiple breakpoints on the reference genome sequence, wherein the number of the reads on either side of each breakpoint are significantly different; determining, based on the plurality of breakpoints, a detection window on the reference genome; determining, based on the reads falling in the detection window, a parameter; and determining, based on the difference between the first parameter and a preset threshold, whether a copy number variation exists in the sample genome against the detection window.
Abstract translation: 提供了用于确定样本基因组中是否存在拷贝数变异的方法，系统和计算机可读介质。 该方法包括对样品基因组进行测序以获得通过多次读取形成的测序结果; 将测序结果与参考基因组序列进行比较，以确定参考基因组序列上读数的分布; 基于参考基因组序列上的读数的分布来确定参考基因组序列上的多个断点，其中每个断点的任一侧的读数显着不同; 基于所述多个断点确定所述参考基因组上的检测窗口; 基于落在检测窗口中的读取来确定参数; 以及基于所述第一参数和预设阈值之间的差来确定所述样本基因组中是否存在根据所述检测窗口的拷贝数变异。
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10.发明申请公开(公告)号：US20140274745A1
公开(公告)日：2014-09-18
申请号：US14354109
申请日：2011-10-28
Applicant: Fang Chen , Xiaoyu Pan , Shengpei Chen , Xuchao Li , Hui Jiang , Xiuqing Zhang
Inventor： Fang Chen , Xiaoyu Pan , Shengpei Chen , Xuchao Li , Hui Jiang , Xiuqing Zhang
CPC classification number: C12Q1/6874 , C12Q1/6883 , C12Q2600/156 , G16B30/00
Abstract: The present invention relates to the field of genomic mutation detection, and in particular, to the detection of the copy number variation (CNV) in cellular chromosomal DNA fragments. The present invention also relates to the detection of diseases related to the copy number variation in the cellular chromosomal DNA fragments.
Abstract translation: 本发明涉及基因组突变检测领域，特别涉及检测细胞染色体DNA片段中的拷贝数变异（CNV）。 本发明还涉及与细胞染色体DNA片段的拷贝数变异相关的疾病的检测。
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