公开(公告)号：US20180043106A1

公开(公告)日：2018-02-15

申请号：US15674974

申请日：2017-08-11

Applicant: Insulet Corporation

Inventor： David NAZZARO

IPC: A61M5/315

CPC classification number: A61M5/31578 ,  A61M5/145 ,  A61M5/2429 ,  A61M5/283 ,  A61M5/31513 ,  A61M5/31535 ,  A61M2005/3109

Abstract: Plunger systems for expelling a liquid drug from a drug container within a wearable drug delivery device are provided. A rotation system coupled to a plunger rotates the plunger about a central axis of the plunger to overcome a static friction between the plunger and the drug container. After rotating the plunger, a drive system moves the plunger forward into the drug container to expel the liquid drug for delivery to the patient. A collapsible plunger includes a cavity. A radial torsion spring positioned in the cavity can provide an outward radial force on the collapsible plunger. The cavity enables the collapsible plunger to compress radially when entering and passing through a region of a drug container having a relatively narrower width. The radial torsion spring can radially expand the collapsible plunger when entering and passing through a region of the drug container having a relatively wider width.

公开(公告)号：US20250108165A1

公开(公告)日：2025-04-03

申请号：US18929087

申请日：2024-10-28

Applicant: INSULET CORPORATION

Inventor： Steven CARDINALI ,  David NAZZARO ,  Ian MCLAUGHLIN

IPC: A61M5/172

Abstract: Embodiments of the present disclosure relate to approaches for more efficiently measuring glucose levels using a wearable drug delivery device. In some embodiments, the wearable drug delivery device may include a needle deployment component including a cannula and an optical conduit deployable into a user, the cannula operable to deliver a liquid drug to the user. The wearable drug delivery device may further include a glucose monitor including an optical sensor, the optical sensor operable to measure a light output received via the optical conduit.

公开(公告)号：US20240252753A1

公开(公告)日：2024-08-01

申请号：US18633816

申请日：2024-04-12

Applicant: INSULET CORPORATION

Inventor： Yibin ZHENG ,  Joon Bok LEE ,  Steven CARDINALI ,  Jason O'CONNOR ,  Eric BENJAMIN ,  Ian MCLAUGHLIN ,  David NAZZARO ,  Ashutosh ZADE

IPC: A61M5/172 ,  A61M5/142 ,  G01N33/49 ,  G16H10/60 ,  G16H20/17 ,  G16H20/60 ,  G16H40/40 ,  G16H40/67 ,  G16H50/30 ,  G16H50/70

CPC classification number: A61M5/1723 ,  A61M5/14248 ,  G01N33/49 ,  G16H10/60 ,  G16H20/17 ,  G16H20/60 ,  G16H40/40 ,  G16H40/67 ,  G16H50/30 ,  G16H50/70 ,  A61M2005/1726 ,  A61M2205/505 ,  A61M2205/52 ,  A61M2230/201

Abstract: Disclosed are a device, system, methods and computer-readable medium products that provide an updated insulin-to-carbohydrate ratio and an updated total daily insulin. The described processes may be used for periodic updating of the insulin-to-carbohydrate ratio and the total daily insulin. The insulin-to-carbohydrate ratio and/or the total may be used in the calculation of new doses of insulin that a drug delivery device may be commanded to deliver to a user.

公开(公告)号：US20230277762A1

公开(公告)日：2023-09-07

申请号：US18176969

申请日：2023-03-01

Applicant: INSULET CORPORATION

Inventor： Eric DUHAMEL ,  John D′ARCO ,  David NAZZARO ,  James CAUSEY

IPC: A61M5/142

CPC classification number: A61M5/14248 ,  A61B5/14532

Abstract: Disclosed herein is a combination of an automated insulin delivery system and a continuous glucose monitor integrated into a single, wearable package. The system may use any combination of delivery methods and detection methods, wherein the delivery methods include a cannula, a microneedle array, and a transdermal patch, and wherein the detection methods include electrochemical methods, opto-fluorescent methods, and spectrographic methods.

公开(公告)号：US20230162833A1

公开(公告)日：2023-05-25

申请号：US18151582

申请日：2023-01-09

Applicant: INSULET CORPORATION

Inventor： David NAZZARO ,  Steven CARDINALI ,  Nicholas CONTE ,  Daniel ALLIS ,  Jason O'CONNOR ,  Joon Bok LEE ,  Ashutosh ZADE ,  Timothy HENNING ,  Thomas METZMAKER ,  Ian MCLAUGHLIN

IPC: G16H20/60 ,  G16H20/17

CPC classification number: G16H20/60 ,  G16H20/17

Abstract: Disclosed are examples of a device, a system, methods and computer-readable medium products operable to implement functionality to determine and respond to a purpose of a meal. An algorithm or application may receive data that may include data related to a meal purpose from data sources and determine whether any of the data received from the plurality of data sources was received from a direct data source or an indirect data source. The data may be evaluated to determine a purpose of the meal. Based on the results of the evaluation, instructions may be generated to provide an appropriate response based on the determined purpose of the meal. The generated instructions to provide the appropriate response based on the determined purpose of the meal may be output.

公开(公告)号：US20220331521A1

公开(公告)日：2022-10-20

申请号：US17855910

申请日：2022-07-01

Applicant: Insulet Corporation

Inventor： David NAZZARO ,  Ian MCLAUGHLIN ,  Maureen MCCAFFREY ,  Simon KOZIN ,  Jackie MAC

IPC: A61M5/20 ,  A61M5/142 ,  A61M5/315

Abstract: A wearable drug delivery device that can deliver a liquid drug stored in a container to a patient is provided. The container can be a prefilled cartridge that can be loaded into the drug delivery device by the patient or that can be preloaded within the drug delivery device when provided to the patient. A sealed end of the container is pierced to couple the stored liquid drug to a needle conduit that is coupled to a needle insertion component that provides access to the patient. A drive system of the drug delivery device can expel the liquid drug from the cartridge to the patient through the needle conduit. The drive system can be controlled to provide the liquid drug to the patient in a single dose or over multiple doses.

公开(公告)号：US20220233765A1

公开(公告)日：2022-07-28

申请号：US17580249

申请日：2022-01-20

Applicant: Insulet Corporation

Inventor： David NAZZARO ,  John D'ARCO ,  Nicholas CONTE ,  Kepei SUN

IPC: A61M5/142

Abstract: In an exemplary embodiment, a drug delivery device is configured for Body Channel Communication (BCC). The drug delivery device may include a conductive element embedded in an adhesive patch that secures the drug delivery device to the user. This conductive element acts as a coupler to the body of the user. Another conductive element may also be provided at a face of the housing. This conductive element acts as the other end of the coupler formed with the conductive coil in the adhesive patch. The conductive coil in the adhesive patch conforms well to the user's skin surface and thus facilitates a good quality coupling with the user.

公开(公告)号：US20220192543A1

公开(公告)日：2022-06-23

申请号：US17554455

申请日：2021-12-17

Applicant: Insulet Corporation

Inventor： David NAZZARO ,  John D'ARCO ,  Nicholas CONTE ,  Kepei SUN

IPC: A61B5/145 ,  A61B5/1486 ,  A61B5/00

Abstract: Exemplary embodiments may provide an adhesive pad that is designed to be used with an on-body medical device. The adhesive pad may partially or fully surround a perimeter of the on-body medical device. The adhesive pad may be the primary mechanism or may provide an additional mechanism for helping to secure the on-body medical device to the user. In addition, the adhesive pad may include a metallic coil, such as a metal loop, that is woven into the adhesive pad or otherwise inserted into or secured to the adhesive pad. The metallic coil may play multiple roles. First, the metallic coil may act as an antenna to facilitate wireless communications with the on-body medical device, such as NFC communications. In addition, the metallic coil may serve as a power source for electric components positioned on the adhesive pad.

公开(公告)号：US20220096749A1

公开(公告)日：2022-03-31

申请号：US17487570

申请日：2021-09-28

Applicant: Insulet Corporation

Inventor： Steven CARDINALI ,  David NAZZARO ,  Ian MCLAUGHLIN

IPC: A61M5/172

Abstract: Embodiments of the present disclosure relate to approaches for more efficiently measuring glucose levels using a wearable drug delivery device. In some embodiments, the wearable drug delivery device may include a needle deployment component including a cannula and an optical conduit deployable into a user, the cannula operable to deliver a liquid drug to the user. The wearable drug delivery device may further include a glucose monitor including an optical sensor, the optical sensor operable to measure a light output received via the optical conduit.

公开(公告)号：US20210379282A1

公开(公告)日：2021-12-09

申请号：US17403784

申请日：2021-08-16

Applicant: Insulet Corporation

Inventor： Jason O'CONNOR ,  Daniel ALLIS ,  David NAZZARO ,  John R. Bussiere ,  John D'ARCO

IPC: A61M5/172 ,  G16H40/63 ,  G16H20/17 ,  A61M5/142

Abstract: Systems and methods for automatically delivering medication to a user. An automated drug delivery system may include a sensor and a wearable automated drug delivery device. The wearable automated drug delivery device may be configured to couple to the skin of a user and may include a controller and a pump. The pump may be configured to output the medication. The controller may be within the wearable automated drug delivery device. The sensor may be coupled to the user and may be configured to collect information regarding the user. The controller of the wearable automated drug delivery device may use the collected information to locally determine an amount of medication to be output from the wearable automated drug delivery device and cause delivery of the amount of medication.