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公开(公告)号:US07115612B2
公开(公告)日:2006-10-03
申请号:US10474916
申请日:2002-04-08
申请人: Tobias Wunberg , Wolfgang Bender , Peter Eckenberg , Sabine Hallenberger , Kerstin Henninger , Jörg Keldenich , Armin Kern , Siegfried Raddatz , Jürgen Reefschläger , Gunter Schmidt , Holger Zimmermann , Franz Zumpe , Martin Radtke
发明人: Tobias Wunberg , Wolfgang Bender , Peter Eckenberg , Sabine Hallenberger , Kerstin Henninger , Jörg Keldenich , Armin Kern , Siegfried Raddatz , Jürgen Reefschläger , Gunter Schmidt , Holger Zimmermann , Franz Zumpe , Martin Radtke
IPC分类号: A61K31/497 , A61K31/4709 , A61K31/4439 , A61K31/433 , A61K31/4245
CPC分类号: C07D271/06 , C07D413/04 , C07D417/04
摘要: The present invention relates to novel sulphonamides of the general formula (I) in which the substituents R1, R2, R3, R4 and A and X are as defined in claim 1 and other claims, and also to processes for their preparation and to their use as antiviral agents, in particular against cytomegaloviruses.
摘要翻译: 本发明涉及通式(I)的新型磺酰胺,其中取代基R 1,R 2,R 3,R 3, A 4和A和X如权利要求1和其它权利要求中所定义,并且还涉及其制备方法及其作为抗病毒剂,特别是针对巨细胞病毒的用途。
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公开(公告)号:US06500817B1
公开(公告)日:2002-12-31
申请号:US09914554
申请日:2001-08-31
申请人: Rüdiger Fischer , Gerald Kleymann , Judith Baumeister , Wolfgang Bender , Ulrich Betz , Peter Eckenberg , Gabriele Handke , Martin Hendrix , Udo Schneider , Olaf Weber , Kerstin Henninger , Axel Jensen , Jörg Keldenich
发明人: Rüdiger Fischer , Gerald Kleymann , Judith Baumeister , Wolfgang Bender , Ulrich Betz , Peter Eckenberg , Gabriele Handke , Martin Hendrix , Udo Schneider , Olaf Weber , Kerstin Henninger , Axel Jensen , Jörg Keldenich
IPC分类号: A61K31426
CPC分类号: C07D231/12 , C07D233/56 , C07D249/08 , C07D277/54 , C07D417/12 , C07D487/04
摘要: The present invention relates to thiazolylurea derivatives, a process for their preparation, and their use as pharmaceuticals, in particular as antiviral pharmaceuticals.
摘要翻译: 本发明涉及噻唑基脲衍生物,其制备方法及其作为药物,特别是作为抗病毒药物的用途。
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公开(公告)号:US08318761B2
公开(公告)日:2012-11-27
申请号:US12203793
申请日:2008-09-03
申请人: Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
发明人: Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
IPC分类号: A01N43/40 , A61K31/435 , A61K31/44
CPC分类号: C07D413/04 , C07D213/73
摘要: The invention relates to substituted arylsulfonamides of formula (I) and methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
摘要翻译: 本发明涉及式(I)的取代芳基磺酰胺及其制备方法及其用于生产用于治疗和/或预防疾病的药物的用途,特别是用作抗病毒剂,特别是用于巨细胞病毒的药物。
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公开(公告)号:US20110172207A1
公开(公告)日:2011-07-14
申请号:US12884113
申请日:2010-09-16
申请人: Rudolf SCHOHE-LOOP , Reinhold Welker , Arnold Paessens , Marcus Bauser , Friederike Stoll , Frank Dittmer , Kerstin Henninger , Daniela Paulsen , Dieter Lang
发明人: Rudolf SCHOHE-LOOP , Reinhold Welker , Arnold Paessens , Marcus Bauser , Friederike Stoll , Frank Dittmer , Kerstin Henninger , Daniela Paulsen , Dieter Lang
IPC分类号: A61K31/4155 , C07D413/06 , C07D403/06 , C07D417/06 , A61K31/5377 , A61K31/553 , A61K31/427 , A61K31/5386 , A61K31/541 , A61K31/496 , A61P31/12 , A61P31/18
CPC分类号: C07D231/14 , A61K31/4155 , C07D401/06 , C07D403/06 , C07D413/06 , C07D417/06 , C07D451/06 , C07D491/08 , C07D498/08
摘要: The present invention relates to novel substituted pyrazolamides, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of retroviral diseases, in humans and/or animals.
摘要翻译: 本发明涉及新型取代的吡唑啉酰胺,其制备方法,其用于治疗和/或预防疾病的用途,以及其用于制备用于治疗和/或预防疾病尤其是逆转录病毒疾病的药物的用途 ,在人类和/或动物中。
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公开(公告)号:US20090176842A1
公开(公告)日:2009-07-09
申请号:US12203793
申请日:2008-09-03
申请人: Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
发明人: Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
IPC分类号: A61K31/4439 , C07D413/04 , C07D213/73 , A61P31/12
CPC分类号: C07D413/04 , C07D213/73
摘要: The invention relates to substituted arylsulfonamides of formula (I) and methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
摘要翻译: 本发明涉及式(I)的取代芳基磺酰胺及其制备方法及其用于生产用于治疗和/或预防疾病的药物的用途,特别是用作抗病毒剂,特别是用于巨细胞病毒的药物。
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公开(公告)号:US20070293478A1
公开(公告)日:2007-12-20
申请号:US11655589
申请日:2007-01-19
申请人: Holger Zimmermann , Rudolph Schohe-loop , Kerstin Henninger , Daniela Paulsen , Thomas Roelle , Dieter Lang , Kai Thede , Chantal Fuerstner , David Brueckner , Johannes Koebberling , Marcus Bauser
发明人: Holger Zimmermann , Rudolph Schohe-loop , Kerstin Henninger , Daniela Paulsen , Thomas Roelle , Dieter Lang , Kai Thede , Chantal Fuerstner , David Brueckner , Johannes Koebberling , Marcus Bauser
IPC分类号: A61K31/497 , A61K31/5377 , A61K31/5513 , A61P31/22 , C07D243/08 , C07D401/02 , C07D413/14
CPC分类号: C07D215/56 , C07D401/04
摘要: The invention relates to substituted quinolones and to processes for their preparation as well as to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
摘要翻译: 本发明涉及取代的喹诺酮及其制备方法,以及它们用于生产用于治疗和/或预防疾病的药物的用途,特别是用作抗病毒剂,特别是用于巨细胞病毒的药物。
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公开(公告)号:US20070099929A1
公开(公告)日:2007-05-03
申请号:US11455253
申请日:2006-06-16
申请人: Kai Thede , Tobias Wunberg , Timothy Lowinger , Diana Koletzki , Andreas Urban , Judith Baumeister , Kerstin Henninger
发明人: Kai Thede , Tobias Wunberg , Timothy Lowinger , Diana Koletzki , Andreas Urban , Judith Baumeister , Kerstin Henninger
IPC分类号: A61K31/496 , A61K31/453 , A61K31/4436 , A61K31/4025 , A61K31/381 , C07D409/02
CPC分类号: C07D409/04 , C07D333/38 , C07D409/12 , C07D409/14 , C07D417/04
摘要: The invention relates to substituted thiophenes and processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, in particular for hepatitis C viruses.
摘要翻译: 本发明涉及取代的噻吩及其制备方法,其用于治疗和/或预防疾病的用途及其用于生产用于治疗和/或预防疾病,特别是用作抗病毒剂的药物的用途 特别适用于丙型肝炎病毒。
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公开(公告)号:US20050107288A1
公开(公告)日:2005-05-19
申请号:US10490192
申请日:2002-09-06
申请人: Berthold Hinzen , Heike Brotz-Oesterhelt , Rainer Endermann , Kerstin Henninger , Holger Paulsen , Siegfried Raddatz , Thomas Lampe , Veronika Hellwig , Andreas Schumacher
发明人: Berthold Hinzen , Heike Brotz-Oesterhelt , Rainer Endermann , Kerstin Henninger , Holger Paulsen , Siegfried Raddatz , Thomas Lampe , Veronika Hellwig , Andreas Schumacher
摘要: The present invention relates to compounds of the general formula (I), processes for their preparation, pharmaceutical compositions comprising them, and their use in the treatment of diseases in humans or animals.
摘要翻译: 本发明涉及通式(I)的化合物,其制备方法,包含它们的药物组合物及其在治疗人或动物疾病中的用途。
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公开(公告)号:US20050059658A1
公开(公告)日:2005-03-17
申请号:US10482520
申请日:2002-06-17
申请人: Tobias Wunberg , Ulrich Betz , Sabine Hallenberger , Gerald Kleymann , Thomas Lampe , Susanne Nikolic , Jurgen Reefschlager , Franz Zumpe , Marcus Bauser , Wolfgang Bender , Rolf Grosser , Kerstin Henninger , Guy Hewlett , Axel Jensen , Jorg Keldenich , Holger Zimmermann
发明人: Tobias Wunberg , Ulrich Betz , Sabine Hallenberger , Gerald Kleymann , Thomas Lampe , Susanne Nikolic , Jurgen Reefschlager , Franz Zumpe , Marcus Bauser , Wolfgang Bender , Rolf Grosser , Kerstin Henninger , Guy Hewlett , Axel Jensen , Jorg Keldenich , Holger Zimmermann
IPC分类号: A61K31/50 , A61K31/501 , A61P31/12 , C07D237/04 , C07D237/32 , C07D417/12
CPC分类号: C07D417/12 , C07D237/04 , C07D237/32
摘要: The invention relates to novel compounds, to a method for the production of said compounds and to the use thereof as medicaments, more particularly as antiviral agents, especially against cytomegalovirus.
摘要翻译: 本发明涉及新化合物,所述化合物的制备方法及其作为药物的用途,更特别地涉及抗病毒剂,特别是抗巨细胞病毒。
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