摘要:
Disclosed is a novel photosensitizer based on polymer derivatives-photosensitizer conjugates for photodynamic therapy capable of being selectively accumulated in cancerous tissues and producing singlet oxygen or free radical by laser irradiation. The polymer derivatives-photosensitizer conjugates for photodynamic therapy are prepared as nano-sized particles, and have excellent selection and accumulation ratio for cancerous tissues. The photosensitizer conjugates can produce singlet oxygen or free radical by a specific laser wavelength. Owing to the excellent selection and accumulation ratio for cancerous tissues, the conjugates minimizes photo-cytotoxicity of the conventional photosensitizer having a low molecular amount. Accordingly, the conjugates are very useful as a photosensitizes for photodynamic therapy with reduced side effects and excellent therapeutic effectiveness.
摘要:
A dry type adhesive device for teeth whitening in which a peroxide tooth whitening agent is stabilized is disclosed. The dry type adhesive device for tooth whitening comprises a matrix type adhesive layer and a backing layer wherein the adhesive layer contains a peroxide as a teeth whitening agent and a hydrophilic glassy polymer as a base polymer so that the hydrophilic glassy polymer provides strong adhesion to teeth when hydrated at the enamel layer of the teeth in the moist oral cavity and the whitening agent is released. In particular, although the dry type adhesive device is touched with the hands or contact the skin during attaching to the teeth prior to hydration, no stickiness and releasing of the whitening agent takes place, thus being safe. In addition, since the dry type patch has strong adhesive strength to the teeth and excellent adhesion maintenance after being hydrated and attached to the teeth, it can remain attached to the teeth for a long time and thus exhibits excellent whitening effect even low concentrations of a whitening agent. Furthermore, the dry type adhesive device can provide excellent whitening within a short period of time.
摘要:
Provided is a method for screening a biological molecule rapidly and economically with high-throughput using microbeads encoded with silver nanoparticles and a chemical compound and dielectrophoresis. A biological screening method particularly utilizes microbeads encoded with silver nanoparticles and a specific chemical compound and dielectrophoresis. Since this screening method does not use a fluorescent material and a dying agent, which are typically used in the conventional screening method, it is non-toxic and economical. Also, this screening method allows simultaneous identification of many target materials. Accordingly, a leading compound can be screened within a short period of time, and thus, this screening method can be implemented as an economical and effective system for developing new pharmaceutical products.
摘要:
The invention provides a cutting segment for a cutting tool for cutting or drilling a brittle work piece such as stone, bricks, concrete and asphalt, and a cutting tool having the cutting segment. The cutting segment includes a cutting surface for cutting a work piece and a plurality of abrasive particle layers. The abrasive particle layers are disposed perpendicular to a cutting direction. Each of the abrasive layers has a plurality of abrasive particle rows in a width direction of the cutting segment. Each of the abrasive rows has a plurality of abrasive particles arranged in a line. Further, the abrasive layers have a plurality of blank sections therebetween. In the blanks sections, abrasive particles are absent or have a concentration of 70% or less with respect to those in the abrasive rows. In addition, the blank sections include relatively thick blank sections and relatively thin blank sections.
摘要:
Disclosed are a communication mediation apparatus and a method for controlling the same for performing communication mediation while reducing a communication miss rate caused by collision of data. A performance of a moving object recognition system unavoidably varies with the number of moving objects to be recognized by a controller, and with a mediation parameter for use in a communication mediation algorithm. The apparatus/method dynamically varies a mediation parameter according to a difference in numbers of many moving objects, thus reducing a communication miss rate regardless of the difference (i.e., traffic volume variation) in numbers of the moving objects.
摘要:
The present invention relates to a novel bipyridinyl derivative having a structure of formula (1) and its pharmaceutically acceptable salts, optical isomer and method for preparing it as a highly selective cyclooxygenase-2 inhibitor, wherein R is defined in this specification.
摘要:
An apparatus and method for controlling a plurality of speakers, comprising an amplifier for amplifying and outputting a play signal to be played over the speakers; and at least one sensor disposed proximal to at least one of the speakers for sensing at least one environmental condition and outputting sensing data to a controller, wherein the controller adjusts the play signal to compensate for environmental changes based on the sensing data.
摘要:
The present invention relates to a dry type tooth whitening patch comprising peroxide as a tooth whitening agent. In particular, disclosed is a dry type tooth whitening patch in which a peroxide is contained, as a teeth whitening agent, in a matrix type adhesive layer. The adhesive layer includes, as a base polymer thereof, a hydrophilic glass polymer which provides a strong adhesion to teeth while releasing the tooth whitening agent when hydrated on the enamel layers of teeth in the moist oral cavity. The dry type patch according to the present invention is convenient in use, as compared to wet type patches. Further, it exhibits a superior adhesion while being maintained in a state attached to the teeth for a lengthened period of time so as to assure an enough contact time between the whitening agent in the patch and stains on the teeth, thereby giving a sufficient whitening effect.
摘要:
An air conditioning unit having a return air inlet and a supply air outlet upon the roof of a vehicle that includes a mounting frame located within an opening in the roof of a vehicle with the frame extending into the comfort region of said vehicle, with said comfort region having a front and rear section. The air conditioning unit is supported upon the top of the frame so that the return air inlet and supply air outlet are in fluid flow communication with the interior of said frame, which is enclosed at the bottom by a floor panel. A partition extends across the width of the frame dividing the frame into a return air compartment that communicates with the return air inlet of the air conditioning unit and a supply air compartment that communicates with the supply air outlet of the air conditioning unit. Longitudinal supply ducts are mounted in the opposed end walls of said frame and are in direct fluid flow communication with the frame supply air compartment. The air supply compartment further includes means for evenly distributing conditioned air to both the front and rear sections of the comfort region of the vehicle.
摘要:
A composition can include a nanostructure, and a linker associated with the nanostructure, wherein the linker is configured to interact with a capture protein. The nanostructure can include a single-walled carbon nanotube. A plurality of the compositions can be configured in an array.