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    METHOD OF MANAGING SECURE COMMUNICATIONS
    41.
    发明申请
    METHOD OF MANAGING SECURE COMMUNICATIONS 审中-公开
    管理安全通信的方法

    公开(公告)号：US20100318788A1

    公开(公告)日：2010-12-16

    申请号：US12483525

    申请日：2009-06-12

    申请人： Alexandro Salvarani ,  Ming Huang ,  Harvey Rubin ,  Hsien-Chuen Yu

    发明人： Alexandro Salvarani ,  Ming Huang ,  Harvey Rubin ,  Hsien-Chuen Yu

    IPC分类号： H04L9/32 ,  H04L9/30

    CPC分类号： H04L9/3263 ,  H04L2209/80

    摘要： An exemplary method of managing secure communications between nodes includes receiving a public key of a node associated with a certification authority. A root node certificate is provided to the node responsive to the received public key. The root node certificate indicates that the received public key belongs to the node. A root self-signed certificate corresponding to a public key of the certification authority is also provided to the node.

    摘要翻译： 管理节点之间的安全通信的示例性方法包括接收与认证机构相关联的节点的公共密钥。 响应于所接收的公共密钥，向节点提供根节点证书。 根节点证书表示接收到的公钥属于节点。 与认证机构的公钥相对应的根自签名证书也被提供给节点。

    Failure recovery in a multiprocessor configuration
    42.
    发明授权
    Failure recovery in a multiprocessor configuration 有权
    多处理器配置中的故障恢复

    公开(公告)号：US07210069B2

    公开(公告)日：2007-04-24

    申请号：US10436062

    申请日：2003-05-13

    申请人： Alejandro A. Kapauan ,  Michael John Lemke ,  Harvey Rubin ,  Omar Hernando Salvador

    发明人： Alejandro A. Kapauan ,  Michael John Lemke ,  Harvey Rubin ,  Omar Hernando Salvador

    IPC分类号： G06F11/00

    CPC分类号： G06F11/2007

    摘要： A multiprocessor configuration includes a plurality of processing groups connected to form both a first and second communication path, and an interpath connection connecting the first and second communication paths. The first and second communication paths and the interpath connection provide allow communication between processors in different processing groups even if one processing group fails and, thus, creates a discontinuity in both the first and second communication paths. One or more processors in each processing group may be operable to perform fault recovery in response to a detected failure in another processing group.

    摘要翻译： 多处理器配置包括连接以形成第一和第二通信路径的多个处理组以及连接第一和第二通信路径的间接连接。 第一和第二通信路径和间路连接提供允许在不同处理组中的处理器之间的通信，即使一个处理组发生故障，并因此在第一和第二通信路径中产生不连续性。 每个处理组中的一个或多个处理器可以用于响应于另一个处理组中检测到的故障来执行故障恢复。

    CDMA transmitter and method generating combined high-rate and low-rate CDMA signals
    43.
    发明授权
    CDMA transmitter and method generating combined high-rate and low-rate CDMA signals 有权

    公开(公告)号：US06781980B1

    公开(公告)日：2004-08-24

    申请号：US09176922

    申请日：1998-10-22

    申请人： Miguel Dajer ,  Peter K. LaConte ,  Harvey Rubin

    发明人： Miguel Dajer ,  Peter K. LaConte ,  Harvey Rubin

    IPC分类号： H04B7216

    CPC分类号： H04B1/0483 ,  H04B1/406 ,  H04B1/707 ,  H04B2201/70703

    摘要： A wideband code division multiple access (CDMA) communication system overlayed on an IS-95 network generates two or more digital bit streams from a group of wideband digital data streams, each digital bit stream spread to form a CDMA component signal. Each CDMA component signal is combined with a corresponding IS-95 digital bit stream to form a composite CDMA signal, allowing a base station to share transmitter subsystems between the wideband and IS-95 systems. For up to three carrier frequencies, up to three composite CDMA signals are employed. A digital bit stream for a group of summed user conversations in the IS-95 system modulates a respective RF carrier frequency to generate a low-power RF signal. The CDMA component signals of the wideband CDMA system are generated so each has a chip rate identical to the chip rate of the digital bit streams of the IS-95 system. The baseband digital data streams for all wideband user conversations are summed digitally for each targeted RF carrier frequency to produce the composite wideband digital signal for each targeted frequency. In one application, each composite wideband digital signal, each at the IS-95 chip rate, is then used to modulate a carrier frequency which is either the same, or has approximately the same frequency and phase as the carrier frequency used in the IS-95 system. Three low-power RF signals are produced in the wideband system, each having the same spectral characteristics as the corresponding low-power RF signals generated in the IS-95 system. These low-power RF signals at the same frequency are combined into a single signal provided to the amplifier and antenna subsystem of a base station transmitter. In another application, each composite digital signal is digitally combined with a respective IS-95 digital bit stream prior to modulation by respective RF carrier. Therefore, signal combining between the IS-95 and wideband CDMA portions of a base station system is accomplished either digitally or with RF signals prior to amplification, thereby allowing the IS-95 system and wideband CDMA system portions of the base station to share RF filters, amplifiers and antennas of the base station transmitters.

    Method and system for recovering from a software failure
    44.
    发明授权
    Method and system for recovering from a software failure 有权
    从软件故障中恢复的方法和系统

    公开(公告)号：US06314532B1

    公开(公告)日：2001-11-06

    申请号：US09205735

    申请日：1998-12-04

    申请人： Douglas Streeter Daudelin ,  Harvey Rubin

    发明人： Douglas Streeter Daudelin ,  Harvey Rubin

    IPC分类号： G06F1100

    CPC分类号： G06F11/1433 ,  G06F11/1417 ,  H04W24/04

    摘要： A method and system recover from a failure of an operational software program. A second software program which is known to function properly and is capable of downloading an updated copy of operational software is stored on the computer with the first software program. The second software program is a boot program which monitors resets of the first software program, determines if the number of resets which have occurred without the operational software first having reached a set operating point (such as establishing communication with a remote computer) reaches a threshold, and preempts operation of the first software program when the threshold is reached.

    摘要翻译： 方法和系统从操作软件程序的故障中恢复。 已知可正常工作并且能够下载更新的操作软件的副本的第二软件程序使用第一软件程序存储在计算机上。 第二软件程序是监视第一软件程序的复位的引导程序，确定在没有操作软件的情况下首先已经达到设定的操作点（例如建立与远程计算机的通信）的复位次数达到阈值 并且当达到阈值时，抢占第一软件程序的操作。

    Method for remotely and reliably updating of the software on a computer with provision for roll back
    45.
    发明授权
    Method for remotely and reliably updating of the software on a computer with provision for roll back 失效
    用于在计算机上远程可靠地更新软件的方法，其中提供回滚

    公开(公告)号：US6141683A

    公开(公告)日：2000-10-31

    申请号：US16574

    申请日：1998-01-30

    申请人： Mark Heinrich Kraml ,  Jane Mary Leonard ,  Harvey Rubin ,  Laurel Ann Salvador

    发明人： Mark Heinrich Kraml ,  Jane Mary Leonard ,  Harvey Rubin ,  Laurel Ann Salvador

    IPC分类号： G06F9/445 ,  G06F15/177

    CPC分类号： G06F8/65 ,  G06F8/67

    摘要： A technique for updating the software in a remote computer (e.g., a base station, a spacecraft in space, an electronic postage meter in an office, a medical monitoring device in a patient's home, etc.) from a central control (e.g., a wireless switching center, the National Aeronautics and Space Administration's Houston Control, a postage meter facility, a medical equipment manufacturer's factory, etc.) is disclosed. An illustrative embodiment of the present invention comprises: checking the integrity of a first software application at a first location in a first memory that is pointed to by a first address in a pointer; copying the first software application from the first memory to the second memory and executing the first software application from the second memory, when the integrity of the first software application is nominal; transmitting a first message indicating that the integrity of the first software application is not nominal, when the integrity of the first software application is not nominal; and receiving a first command to store a second address in the pointer, in response to the first message.

    摘要翻译： 一种用于从远程计算机（例如，基站，空间中的航天器，办公室中的电子邮资计费器，患者家庭中的医疗监视设备等）更新软件的技术，其从中央控制器（例如， 无线交换中心，国家航空航天局的休斯顿控制，邮资计费设备，医疗设备制造厂等）。 本发明的说明性实施例包括：在由指针中的第一地址指向的第一存储器中的第一位置处检查第一软件应用的完整性; 当第一软件应用的完整性是标称的时，将第一软件应用从第一存储器复制到第二存储器并且从第二存储器执行第一软件应用; 当第一软件应用的完整性不是名义时，传送指示第一软件应用的完整性不是标称的第一消息; 以及响应于所述第一消息，接收指针中存储第二地址的第一命令。

    .alpha.-1-antichymotrypsin analogues having chymase inhibiting activity
    46.
    发明授权
    .alpha.-1-antichymotrypsin analogues having chymase inhibiting activity 失效
    具有糜酶抑制活性的α-1抗胰凝乳蛋白酶类似物

    公开(公告)号：US5723316A

    公开(公告)日：1998-03-03

    申请号：US221171

    申请日：1994-03-31

    申请人： Barry S. Cooperman ,  Harvey Rubin ,  Norman Schechter ,  Zhi Mei Wang

    发明人： Barry S. Cooperman ,  Harvey Rubin ,  Norman Schechter ,  Zhi Mei Wang

    IPC分类号： C12N15/09 ,  A61K38/00 ,  A61K38/55 ,  A61P7/02 ,  A61P9/00 ,  A61P29/00 ,  A61P31/04 ,  C07H21/04 ,  C07K14/81 ,  C12N1/21 ,  C12N5/10 ,  C12N9/99 ,  C12P21/02 ,  C12R1/19 ,  C12N15/00 ,  A61K38/43

    CPC分类号： C07K14/8121 ,  C07K14/8125 ,  A61K38/00

    摘要： The invention provides analogues of .alpha.-1-antichymotrypsin having amino acid substitutions at position 358. .alpha.-1-antichymotrypsin analogues having amino acid substitutions at positions 356-361 and analogues having amino acid substitutions at positions 356-361 wherein the amino acid at position 358 is substituted are also within the scope of the invention. These analogues exhibit chymase inhibitory activity. Also provided are novel .alpha.-1-antichymotrypsins having an N-terminal extension of methionine-alanine-serine or alanine-serine. Expression vectors for the production of .alpha.-1-antichymotrypsins are also provided. The present invention also provides host cells and cell cultures capable of expressing analogues of .alpha.-1-antichymotrypsin, as well as protein preparations from the host cells. Methods of producing and using the analogues of .alpha.-1-antichymotrypsin to inhibit chymase activity are also provided.

    摘要翻译： 本发明提供了在358位具有氨基酸取代的α-1-抗胰凝乳蛋白酶的类似物。在356-361位具有氨基酸取代的α1-抗胰凝乳蛋白酶类似物和在位置356-361处具有氨基酸取代的类似物，其中位置处的氨基酸 358也在本发明的范围内。 这些类似物表现出糜酶抑制活性。 还提供了具有甲硫氨酸 - 丙氨酸 - 丝氨酸或丙氨酸 - 丝氨酸的N-末端延伸的新型α-1抗胰凝乳蛋白。 还提供了用于产生α-1抗胰凝乳蛋白的表达载体。 本发明还提供能够表达α-1-胰凝乳蛋白酶类似物的宿主细胞和细胞培养物，以及来自宿主细胞的蛋白质制剂。 还提供了产生和使用α-1抗胰凝乳蛋白酶类似物以抑制胃促胰酶活性的方法。

    .alpha.-1-antichymotrypsin, analogues and methods of production
    49.
    发明授权
    .alpha.-1-antichymotrypsin, analogues and methods of production 失效
    α-1抗胰凝乳蛋白酶，类似物和生产方法

    公开(公告)号：US5367064A

    公开(公告)日：1994-11-22

    申请号：US5908

    申请日：1993-01-15

    申请人： Harvey Rubin ,  Zhi M. Wang ,  Barry S. Cooperman ,  Norman Schechter

    发明人： Harvey Rubin ,  Zhi M. Wang ,  Barry S. Cooperman ,  Norman Schechter

    IPC分类号： A61K38/00 ,  C07K14/81 ,  C07H21/04 ,  C07K13/00 ,  C12N15/22

    CPC分类号： C07K14/8125 ,  A61K38/00

    摘要： The invention provides .alpha.-1-antichymotrypsin and protein preparations comprising human .alpha.-1-antichymotrypsin produced by E. coli cells transformed with a DNA sequence encoding human .alpha.-1-antichymotrypsin. The invention also provides methods for producing .alpha.-1-antichymotrypsin. The invention further provides analogues of .alpha.-1-antichymotrypsin that exhibit antichymotrypsin, anti-trypsin and anti-thrombin activity and methods of producing the analogues.

    摘要翻译： 本发明提供了包含用编码人α1-抗胰凝乳蛋白酶的DNA序列转化的大肠杆菌细胞产生的人α1-抗胰凝乳蛋白酶的α-1抗胰凝乳蛋白酶和蛋白质制剂。 本发明还提供了生产α-1抗胰凝乳蛋白酶的方法。 本发明还提供表现出抗胰凝乳蛋白酶，抗胰蛋白酶和抗凝血酶活性的α-1-抗胰凝乳蛋白酶的类似物和产生类似物的方法。