公开(公告)号：US20150020241A1

公开(公告)日：2015-01-15

申请号：US14298785

申请日：2014-06-06

Applicant: Monsanto Technology LLC

Inventor： Wei Wu ,  Qi Wang ,  Michael Edgerton ,  Kim Beazley ,  Jill Deikman ,  Michael W. Petersen ,  Bei Zhang

IPC: C12N15/82

CPC classification number: C12N15/8216 ,  A01H5/00 ,  C12N9/1085 ,  C12N15/8289 ,  C12Y205/01006

Abstract: The present invention provides non-coding regulatory element polynucleotide molecules isolated from the S-adenosyl methionine synthetase (SAMS3) gene of Arabidopsis thaliana and useful for expressing transgenes in plants. The invention further discloses compositions, polynucleotide constructs, transformed host cells, transgenic plants and seeds containing the Arabidopsis thaliana regulatory polynucleotide sequences, and methods for preparing and using the same.

Abstract translation: 本发明提供从拟南芥的S-腺苷甲硫氨酸合成酶（SAMS3）基因中分离的非编码调控元件多核苷酸分子，并且可用于在植物中表达转基因。 本发明还公开了组合物，多核苷酸构建体，转化的宿主细胞，转基因植物和含有拟南芥调节多核苷酸序列的种子，以及制备和使用拟南芥调节多核苷酸序列的方法。

公开(公告)号：US20140004088A1

公开(公告)日：2014-01-02

申请号：US14011647

申请日：2013-08-27

Applicant: Monsanto Technology LLC

Inventor： Andrey A. Boukharov ,  Zijin Du ,  Liang Guo ,  Michelle C. Hresko ,  David K. Kovalic ,  Zhaolong Li ,  Maolong Lu ,  James P. McCarter ,  Nancy M. Miller ,  Mark Vaudin ,  Deryck J. Williams ,  Wei Wu

IPC: C12N15/113 ,  A61K31/713

CPC classification number: C12N15/8285 ,  A01N57/16 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/713 ,  C07K14/435 ,  C07K14/4354 ,  C12N15/113 ,  C12N15/1137 ,  C12N15/8261 ,  C12N15/8273 ,  C12N2310/11 ,  C12Q1/6888 ,  Y02A40/164

Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.

Abstract translation: 本发明涉及鉴定和评估通过抑制一种或多种生物学功能及其用途来控制植物寄生线虫的靶编码序列。 本发明提供用于鉴定这种序列并控制植物寄生线虫种群的方法和组合物。 通过将本发明提供的一种或多种重组双链RNA分子送入线虫，通过抑制线虫基因表达可以获得疾病的减少。 本发明还涉及用于制备表达双链RNA分子的转基因植物以及由此获得的植物细胞和植物的方法。

公开(公告)号：US20250019712A1

公开(公告)日：2025-01-16

申请号：US18905108

申请日：2024-10-02

Applicant: Monsanto Technology LLC

Inventor： Stanislaw Flasinski ,  Barrett C. Foat ,  Mohammed Oufattole ,  Randall W. Shultz ,  Xiaoping Wei ,  Wei Wu ,  Shiaw-Pyng Yang

IPC: C12N15/82

Abstract: The invention provides DNA molecules and constructs, including their nucleotide sequences, useful for modulating gene expression in plants and plant cells. Transgenic plants, plant cells, plant parts, seeds, and commodity products comprising the DNA molecules operably linked to heterologous transcribable polynucleotides are also provided, as are methods of their use.

公开(公告)号：US20240271148A1

公开(公告)日：2024-08-15

申请号：US18630830

申请日：2024-04-09

Applicant: Monsanto Technology LLC

Inventor： Stanislaw Flasinski ,  Charles R. Dietrich ,  Wei Wu ,  Zhaolong Li ,  Bo-Xing Qiu ,  Liang Guo ,  Jaishree M. Chittoor

IPC: C12N15/82 ,  C12N15/113

CPC classification number: C12N15/8221 ,  C12N15/113 ,  C12N15/8222

Abstract: The invention provides DNA molecules and constructs, and their nucleotide sequences, useful for modulating gene expression in plants, and for specifying intracellular or extracellular localization of a gene product of interest. Transgenic plants, plant cells, plant parts, and seeds, comprising the DNA molecules operably linked to heterologous transcribable polynucleotides are also provided.

公开(公告)号：US11492638B2

公开(公告)日：2022-11-08

申请号：US15709291

申请日：2017-09-19

Applicant: MONSANTO TECHNOLOGY LLC

Inventor： James A. Baum ,  Larry A. Gilbertson ,  David K. Kovalic ,  Thomas J. LaRosa ,  Maolong Lu ,  Tichafa R. I. Munyikwa ,  James K. Roberts ,  Wei Wu ,  Bei Zhang

IPC: C12N15/82 ,  A01N63/50 ,  A01N63/60

Abstract: The present invention is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The invention discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.

公开(公告)号：US11180768B2

公开(公告)日：2021-11-23

申请号：US16722287

申请日：2019-12-20

Applicant: Monsanto Technology LLC

Inventor： Stanislaw Flasinski ,  Barrett C. Foat ,  Mohammed Oufattole ,  Randall W. Shultz ,  Xiaoping Wei ,  Wei Wu ,  Shiaw-Pyng Yang

IPC: C12N15/82

Abstract: The invention provides DNA molecules and constructs, including their nucleotide sequences, useful for modulating gene expression in plants and plant cells. Transgenic plants, plant cells, plant parts, seeds, and commodity products comprising the DNA molecules operably linked to heterologous transcribable polynucleotides are also provided, as are methods of their use.

公开(公告)号：US11046966B2

公开(公告)日：2021-06-29

申请号：US16549573

申请日：2019-08-23

Applicant: Monsanto Technology LLC

Inventor： Stanislaw Flasinski ,  Barrett C. Foat ,  Mohammed Oufattole ,  Randall W. Shultz ,  Xiaoping Wei ,  Wei Wu ,  Shiaw-Pyng Yang

IPC: C12N15/82

Abstract: The invention provides DNA molecules and constructs, including their nucleotide sequences, useful for modulating gene expression in plants and plant cells. Transgenic plants, plant cells, plant parts, seeds, and commodity products comprising the DNA molecules operably linked to heterologous transcribable polynucleotides are also provided, as are methods of their use.

公开(公告)号：US20200056195A1

公开(公告)日：2020-02-20

申请号：US16549573

申请日：2019-08-23

Applicant: Monsanto Technology LLC

Inventor： Stanislaw Flasinski ,  Barrett C. Foat ,  Mohammed Oufattole ,  Randall W. Shultz ,  Xiaoping Wei ,  Wei Wu ,  Shiaw-Pyng Yang

IPC: C12N15/82

Abstract: The invention provides DNA molecules and constructs, including their nucleotide sequences, useful for modulating gene expression in plants and plant cells. Transgenic plants, plant cells, plant parts, seeds, and commodity products comprising the DNA molecules operably linked to heterologous transcribable polynucleotides are also provided, as are methods of their use.

公开(公告)号：US20190241906A1

公开(公告)日：2019-08-08

申请号：US16242869

申请日：2019-01-08

Applicant: Monsanto Technology LLC

Inventor： Andrey A. Boukharov ,  Zijin Du ,  Liang Gou ,  Michelle C. Hresko ,  David K. Kovalic ,  Zhaolong Li ,  Maolong Lu ,  James P. McCarter ,  Nancy M. Miller ,  Mark Vaudin ,  Deryck J. Williams ,  Wei Wu

IPC: C12N15/82 ,  A61K31/713 ,  C12N15/113 ,  A01N57/16 ,  C12Q1/6888 ,  C07K14/435 ,  A23L33/105

CPC classification number: C12N15/8285 ,  A01N57/16 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/713 ,  C07K14/435 ,  C07K14/4354 ,  C12N15/113 ,  C12N15/1137 ,  C12N15/8261 ,  C12N15/8273 ,  C12N2310/11 ,  C12Q1/6888 ,  Y02A40/164

Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.

公开(公告)号：US10301625B2

公开(公告)日：2019-05-28

申请号：US15476701

申请日：2017-03-31

Applicant: Monsanto Technology LLC

Inventor： Stanislaw Flasinski ,  Charles R. Dietrich ,  Wei Wu ,  Zhaolong Li ,  Bo-Xing Qiu ,  Liang Guo ,  Jaishree M. Chittoor

IPC: C12N15/113 ,  C12N15/82

Abstract: The invention provides DNA molecules and constructs, and their nucleotide sequences, useful for modulating gene expression in plants, and for specifying intracellular or extracellular localization of a gene product of interest. Transgenic plants, plant cells, plant parts, and seeds, comprising the DNA molecules operably linked to heterologous transcribable polynucleotides are also provided.