公开(公告)号：USRE46033E1

公开(公告)日：2016-06-21

申请号：US14121743

申请日：2014-10-10

Applicant: Monsanto Technology LLC

Inventor： Andrey A. Boukharov ,  Yongwei Cao ,  Stanton B. Dotson ,  Jeffrey M. Koshi ,  David K. Kovalic ,  Jingdong Liu ,  James D. McIninch ,  Wei Wu

IPC: C07H21/04 ,  A01H5/00 ,  C07H21/02 ,  C07K14/415 ,  C12N15/82

CPC classification number: C07K14/415 ,  C12N15/8216 ,  C12N15/8227 ,  C12Q1/6895 ,  C12Q2600/13

Abstract: The present invention discloses rice genomic promoter sequences. The promoters are particularly suited for use in rice and other cereal crops. Methods of modifying, producing, and using the promoters are also disclosed. The invention further discloses compositions, transformed host cells, transgenic plants, and seeds containing the rice genomic promoter sequences, and methods for preparing and using the same.

公开(公告)号：US20180312867A1

公开(公告)日：2018-11-01

申请号：US15979061

申请日：2018-05-14

Applicant: Monsanto Technology LLC

Inventor： Andrey A. Boukharov ,  Zijin Du ,  Liang Guo ,  Michelle C. Hresko ,  David K. Kovalic ,  Zhaolong Li ,  Maolong Lu ,  James P. McCarter ,  Nancy M. Miller ,  Mark Vaudin ,  Deryck J. Williams ,  Wei Wu

IPC: C12N15/82 ,  C12Q1/6888 ,  C07K14/435 ,  A01N57/16 ,  A61K31/713 ,  C12N15/113 ,  A23L33/105

Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.

公开(公告)号：US09388409B2

公开(公告)日：2016-07-12

申请号：US14011647

申请日：2013-08-27

Applicant: Monsanto Technology LLC

Inventor： Andrey A. Boukharov ,  Zijin Du ,  Liang Guo ,  Michelle C. Hresko ,  David K. Kovalic ,  Zhaolong Li ,  Maolong Lu ,  James P. McCarter ,  Nancy M. Miller ,  Mark Vaudin ,  Deryck J. Williams ,  Wei Wu

IPC: C12N15/82 ,  C12N15/87 ,  A01H1/00 ,  C12N15/113 ,  C07K14/435 ,  A61K31/713

CPC classification number: C12N15/8285 ,  A01N57/16 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/713 ,  C07K14/435 ,  C07K14/4354 ,  C12N15/113 ,  C12N15/1137 ,  C12N15/8261 ,  C12N15/8273 ,  C12N2310/11 ,  C12Q1/6888 ,  Y02A40/164

Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.

公开(公告)号：US20190241906A1

公开(公告)日：2019-08-08

申请号：US16242869

申请日：2019-01-08

Applicant: Monsanto Technology LLC

Inventor： Andrey A. Boukharov ,  Zijin Du ,  Liang Gou ,  Michelle C. Hresko ,  David K. Kovalic ,  Zhaolong Li ,  Maolong Lu ,  James P. McCarter ,  Nancy M. Miller ,  Mark Vaudin ,  Deryck J. Williams ,  Wei Wu

IPC: C12N15/82 ,  A61K31/713 ,  C12N15/113 ,  A01N57/16 ,  C12Q1/6888 ,  C07K14/435 ,  A23L33/105

CPC classification number: C12N15/8285 ,  A01N57/16 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/713 ,  C07K14/435 ,  C07K14/4354 ,  C12N15/113 ,  C12N15/1137 ,  C12N15/8261 ,  C12N15/8273 ,  C12N2310/11 ,  C12Q1/6888 ,  Y02A40/164

Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.

公开(公告)号：US10174340B2

公开(公告)日：2019-01-08

申请号：US15194355

申请日：2016-06-27

Applicant: Monsanto Technology LLC

Inventor： Andrey A. Boukharov ,  Zijin Du ,  Liang Guo ,  Michelle C. Hresko ,  David K. Kovalic ,  Zhaolong Li ,  Maolong Lu ,  James P. McCarter ,  Nancy M. Miller ,  Mark Vaudin ,  Deryck J. Williams ,  Wei Wu

IPC: C12N15/82 ,  C07K14/435 ,  A61K31/713 ,  C12N15/113 ,  A23L33/105 ,  A01N57/16 ,  C12Q1/6888

Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.

公开(公告)号：US09988642B2

公开(公告)日：2018-06-05

申请号：US14714068

申请日：2015-05-15

Applicant: Monsanto Technology LLC

Inventor： Andrey A. Boukharov ,  Zijin Du ,  Liang Guo ,  Michelle C. Hresko ,  David K. Kovalic ,  Zhaolong Li ,  Maolong Lu ,  James P. McCarter ,  Nancy M. Miller ,  Mark Vaudin ,  Deryck J. Williams ,  Wei Wu

IPC: C12N15/82 ,  C07K14/435 ,  A61K31/713 ,  C12N15/113 ,  A23L33/105 ,  A01N57/16 ,  C12Q1/68

CPC classification number: C12N15/8285 ,  A01N57/16 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/713 ,  C07K14/435 ,  C07K14/4354 ,  C12N15/113 ,  C12N15/1137 ,  C12N15/8261 ,  C12N15/8273 ,  C12N2310/11 ,  C12Q1/6888 ,  Y02A40/164

Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.

公开(公告)号：US10829781B2

公开(公告)日：2020-11-10

申请号：US15979061

申请日：2018-05-14

Applicant: Monsanto Technology LLC

Inventor： Andrey A. Boukharov ,  Zijin Du ,  Liang Guo ,  Michelle C. Hresko ,  David K. Kovalic ,  Zhaolong Li ,  Maolong Lu ,  James P. McCarter ,  Nancy M. Miller ,  Mark Vaudin ,  Deryck J. Williams ,  Wei Wu

IPC: C12N15/82 ,  C07K14/435 ,  A61K31/713 ,  C12N15/113 ,  A23L33/105 ,  A01N57/16 ,  C12Q1/6888

Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.

公开(公告)号：US20160376606A1

公开(公告)日：2016-12-29

申请号：US15194355

申请日：2016-06-27

Applicant: Monsanto Technology LLC

Inventor： Andrey A. Boukharov ,  Zijin Du ,  Liang Guo ,  Michelle C. Hresko ,  David K. Kovalic ,  Zhaolong Li ,  Maolong Lu ,  James P. McCarter ,  Nancy M. Miller ,  Mark Vaudin ,  Deryck J. Williams ,  Wei Wu

IPC: C12N15/82 ,  A23L33/105 ,  A01N57/16 ,  C12Q1/68 ,  C12N15/113

CPC classification number: C12N15/8285 ,  A01N57/16 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/713 ,  C07K14/435 ,  C07K14/4354 ,  C12N15/113 ,  C12N15/1137 ,  C12N15/8261 ,  C12N15/8273 ,  C12N2310/11 ,  C12Q1/6888 ,  Y02A40/164

Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.

公开(公告)号：US20150252366A1

公开(公告)日：2015-09-10

申请号：US14714068

申请日：2015-05-15

Applicant: Monsanto Technology LLC

Inventor： Andrey A. Boukharov ,  Zijin Du ,  Liang Guo ,  Michelle C. Hresko ,  David K. Kovalic ,  Zhaolong Li ,  Maolong Lu ,  James P. McCarter ,  Nancy M. Miller ,  Mark Vaudin ,  Deryck J. Williams ,  Wei Wu

IPC: C12N15/113 ,  C07K14/435 ,  C12N15/82

CPC classification number: C12N15/8285 ,  A01N57/16 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/713 ,  C07K14/435 ,  C07K14/4354 ,  C12N15/113 ,  C12N15/1137 ,  C12N15/8261 ,  C12N15/8273 ,  C12N2310/11 ,  C12Q1/6888 ,  Y02A40/164

Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.

Abstract translation: 本发明涉及鉴定和评估通过抑制一种或多种生物学功能及其用途来控制植物寄生线虫的靶编码序列。 本发明提供用于鉴定这种序列并控制植物寄生线虫种群的方法和组合物。 通过将本发明提供的一种或多种重组双链RNA分子送入线虫，通过抑制线虫基因表达可以获得疾病的减少。 本发明还涉及用于制备表达双链RNA分子的转基因植物以及由此获得的植物细胞和植物的方法。

公开(公告)号：US20140004088A1

公开(公告)日：2014-01-02

申请号：US14011647

申请日：2013-08-27

Applicant: Monsanto Technology LLC

Inventor： Andrey A. Boukharov ,  Zijin Du ,  Liang Guo ,  Michelle C. Hresko ,  David K. Kovalic ,  Zhaolong Li ,  Maolong Lu ,  James P. McCarter ,  Nancy M. Miller ,  Mark Vaudin ,  Deryck J. Williams ,  Wei Wu

IPC: C12N15/113 ,  A61K31/713

CPC classification number: C12N15/8285 ,  A01N57/16 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/713 ,  C07K14/435 ,  C07K14/4354 ,  C12N15/113 ,  C12N15/1137 ,  C12N15/8261 ,  C12N15/8273 ,  C12N2310/11 ,  C12Q1/6888 ,  Y02A40/164

Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.

Abstract translation: 本发明涉及鉴定和评估通过抑制一种或多种生物学功能及其用途来控制植物寄生线虫的靶编码序列。 本发明提供用于鉴定这种序列并控制植物寄生线虫种群的方法和组合物。 通过将本发明提供的一种或多种重组双链RNA分子送入线虫，通过抑制线虫基因表达可以获得疾病的减少。 本发明还涉及用于制备表达双链RNA分子的转基因植物以及由此获得的植物细胞和植物的方法。