公开(公告)号：US20090010245A1

公开(公告)日：2009-01-08

申请号：US12231563

申请日：2008-09-04

申请人： Patrick Worfolk ,  Xiaoming Zhou

发明人： Patrick Worfolk ,  Xiaoming Zhou

IPC分类号： H04J3/06

CPC分类号： H04W56/002

摘要： A device and method for of synchronizing a MAC superframe of a wireless device is disclosed. The wireless device can be located within a chain of a plurality of other wireless devices. The method includes receiving beacons from at least one other device during a superframe of the wireless device, determining a superframe offset for each of the other wireless devices based on timing of the received beacons, determining a corrective delay based on the superframe offsets, inserting the corrective delay within a current superframe of the wireless device, and inserting a predictive delay within the current superframe, the predictive delay being determined by an estimate of a difference between a frequency a clock of the wireless device and a frequency of a slowest clock of the other wireless devices within the chain.

摘要翻译： 公开了一种用于同步无线设备的MAC超帧的设备和方法。 无线设备可以位于多个其他无线设备的链路内。 该方法包括在无线设备的超帧期间从至少一个其他设备接收信标，基于接收到的信标的定时确定每个其他无线设备的超帧偏移，基于超帧偏移确定校正延迟，插入 在无线设备的当前超帧内的校正延迟，以及在当前超帧内插入预测延迟，所述预测延迟由所述无线设备的时钟频率与所述无线设备的最慢时钟的频率之间的差的估计来确定 链中的其他无线设备。

公开(公告)号：US20070072636A1

公开(公告)日：2007-03-29

申请号：US11239584

申请日：2005-09-29

申请人： Patrick Worfolk ,  Xiaoming Zhou

发明人： Patrick Worfolk ,  Xiaoming Zhou

IPC分类号： H04B7/00 ,  H04B15/00

CPC分类号： H04W56/002

摘要： A device and method for of synchronizing a MAC superframe of a wireless device is disclosed. The wireless device can be located within a chain of a plurality of other wireless devices. The method includes receiving beacons from at least one other device during a superframe of the wireless device, determining a superframe offset for each of the other wireless devices based on timing of the received beacons, determining a corrective delay based on the superframe offsets, inserting the corrective delay within a current superframe of the wireless device, and inserting a predictive delay within the current superframe, the predictive delay being determined by an estimate of a difference between a frequency a clock of the wireless device and a frequency of a slowest clock of the other wireless devices within the chain.

摘要翻译： 公开了一种用于同步无线设备的MAC超帧的设备和方法。 无线设备可以位于多个其他无线设备的链路内。 该方法包括在无线设备的超帧期间从至少一个其他设备接收信标，基于接收到的信标的定时确定每个其他无线设备的超帧偏移，基于超帧偏移确定校正延迟，插入 在无线设备的当前超帧内的校正延迟，以及在当前超帧内插入预测延迟，所述预测延迟由所述无线设备的时钟频率与所述无线设备的最慢时钟的频率之间的差的估计来确定 链中的其他无线设备。

公开(公告)号：US07022714B2

公开(公告)日：2006-04-04

申请号：US10630896

申请日：2003-07-31

申请人： Qun Sun ,  Xiaoming Zhou ,  Donald J. Kyle

发明人： Qun Sun ,  Xiaoming Zhou ,  Donald J. Kyle

IPC分类号： A61K31/454 ,  C07D401/06 ,  C07D401/14

CPC分类号： C07D403/06 ,  C07D235/08 ,  C07D235/12

摘要： This invention relates aryl substituted benzimidazoles of Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein R1, R2, R10 and n are defined in the specification. The invention is also directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.

摘要翻译： 本发明涉及式I的芳基取代的苯并咪唑或其药学上可接受的盐，前药或溶剂合物，其中R 1，R 2，R 10， >和n在本说明书中定义。 本发明还涉及式I化合物用于治疗全身和局部缺血后的神经元损伤，用于治疗或预防神经变性疾病如肌萎缩性侧索硬化（ALS）以及治疗，预防或改善的用途 作为抗惊厥剂，作为抗惊厥剂，作为抗躁狂抑制剂，作为局部麻醉剂，作为抗心律失常药物和用于治疗或预防糖尿病性神经病变。

公开(公告)号：US20160272640A1

公开(公告)日：2016-09-22

申请号：US14655882

申请日：2013-12-23

申请人： Kevin BROWN ,  Dawit TADESSE ,  Naoki TSUNO ,  Nobuyuki TANAKA ,  Xiaoming Zhou ,  SHIONOGI & CO., LTD.

发明人： Kevin Brown ,  Dawit Tadesse ,  Nobuyuki Tanaka ,  Naoki Tsuno ,  Xiaoming Zhou

IPC分类号： C07D471/08 ,  C07D211/58 ,  C07C235/74

CPC分类号： C07D471/08 ,  C07C235/74 ,  C07C2602/46 ,  C07D211/58

摘要： The disclosure relates to Substituted Piperidin-4-amino-Type Compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof wherein R1, R2, R3, Q1, Q2, E1, E2, A, B, D, W, Z, a, b, n, and x are as defined herein, compositions comprising an effective amount of a Substituted Piperidin-4-amino-Type Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted Piperidin-4-amino-Type Compound.

公开(公告)号：US20130342702A1

公开(公告)日：2013-12-26

申请号：US13533706

申请日：2012-06-26

申请人： Xiaopeng Zhang ,  Xiaokang Zhang ,  Jilai Wang ,  Xiaoming Zhou ,  Gang Qiu ,  Liang Shen ,  Chen Feng

发明人： Xiaopeng Zhang ,  Xiaokang Zhang ,  Jilai Wang ,  Xiaoming Zhou ,  Gang Qiu ,  Liang Shen ,  Chen Feng

IPC分类号： H04N5/33 ,  G06K9/00

CPC分类号： G06K9/00255 ,  G06K9/00906 ,  G06K9/2018

摘要： Systems and methods for detecting a live human face in an image are disclosed. The methods and systems are capable of receiving multispectral image data that includes a human face. The multispectral image data can comprise visible light image data and near-infrared (NIR) image data. The multispectral image data can be processed to detect the human face. The detected human face in the visible light image data can be associated with the detected human face in the NIR image data to determine whether the detected human face is a live human face.

摘要翻译： 公开了用于检测图像中的活人脸的系统和方法。 方法和系统能够接收包含人脸的多光谱图像数据。 多光谱图像数据可以包括可见光图像数据和近红外（NIR）图像数据。 可以处理多光谱图像数据以检测人脸。 可见光图像数据中检测到的人脸可以与NIR图像数据中检测到的人脸相关联，以确定检测到的人脸是否是活人脸。

公开(公告)号：US08481743B2

公开(公告)日：2013-07-09

申请号：US12447758

申请日：2007-10-31

申请人： Xiaoming Zhou

发明人： Xiaoming Zhou

IPC分类号： C07D211/56 ,  A61K31/445

CPC分类号： C07D211/58 ,  A61K31/4468 ,  A61K31/58 ,  A61K45/06 ,  C07D401/06 ,  A61K2300/00

摘要： The invention relates to phenylpropionamide compounds of Formula (I): and pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein A, B, R1, R2, R3, R4 and R5 are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula (I) to treat, prevent or ameliorate a disorder responsive to the activation of opioid receptors, particularly μ-opioid receptors. Compounds of the present invention are especially useful for treating pain.

摘要翻译： 本发明涉及式（I）的苯基丙酰胺化合物及其药学上可接受的盐，前药和溶剂化物，其中A，B，R 1，R 2，R 3，R 4和R 5如说明书所述定义。 本发明还涉及式（I）化合物用于治疗，预防或改善对阿片样物质受体，特别是阿片受体的激活有反应的病症。 本发明的化合物特别适用于治疗疼痛。

公开(公告)号：US08349842B2

公开(公告)日：2013-01-08

申请号：US12506040

申请日：2009-07-20

申请人： Qun Sun ,  Kate Xin Wen ,  Xiaoming Zhou

发明人： Qun Sun ,  Kate Xin Wen ,  Xiaoming Zhou

IPC分类号： A61K31/497

CPC分类号： C07D417/14 ,  C07D401/04

摘要： Piperidine Compounds; compositions comprising a Piperidine Compound; and methods for treating or preventing pain, UI, an ulcer, IBD, IBS, an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy, stroke, a seizure, a pruritic condition, psychosis, a cognitive disorder, a memory deficit, restricted brain function, Huntington's chorea, amyotrophic lateral sclerosis, dementia, retinopathy, a muscle spasm, a migraine, vomiting, dyskinesia, or depression in an animal comprising administering to an animal in need thereof an effective amount of a Piperidine Compound are disclosed. In one embodiment, the Piperidine Compound has the formula: and pharmaceutically acceptable salts thereof, wherein Ar1, Ar2, X, R3, R4, and m are as disclosed herein.

公开(公告)号：US20110082152A1

公开(公告)日：2011-04-07

申请号：US12943739

申请日：2010-11-10

申请人： Qun Sun ,  Xiaoming Zhou

发明人： Qun Sun ,  Xiaoming Zhou

IPC分类号： A61K31/501 ,  C07D403/04 ,  C12N5/071 ,  A61P29/02 ,  A61P25/04

CPC分类号： C07D401/04 ,  C07D403/04 ,  C07D417/04

摘要： A compound of formula: wherein Ar, Ar1, Ar2, R3, R4, R5, R6, R13, m, t, and x are disclosed herein, or a pharmaceutically acceptable salt thereof (a “Hydroxyiminopiperazine Compound”); compositions comprising an effective amount of a Hydroxyiminopiperazine Compound; and methods for treating or preventing pain and other conditions in an animal comprising administering to an animal in need thereof an effective amount of a Hydroxyiminopiperazine Compound are disclosed.

摘要翻译： 式中的化合物：其中Ar，Ar1，Ar2，R3，R4，R5，R6，R13，m，t和x在本文中公开，或其药学上可接受的盐（“羟基亚氨基哌嗪化合物”）; 包含有效量的羟基亚氨基哌嗪化合物的组合物; 以及用于治疗或预防动物中的疼痛和其它病症的方法，包括向有需要的动物施用有效量的羟基亚氨基哌嗪化合物。

公开(公告)号：US20110022992A1

公开(公告)日：2011-01-27

申请号：US12933920

申请日：2009-03-24

申请人： Xiaoming Zhou ,  Paul Marcel Carl Lemmens ,  Alphons Antonius Maria Lambertus Bruekers ,  Andrew Alexander Tokmakoff ,  Evelijne Machteld Hart De Ruijter-Bekker ,  Serverius Petrus Paulus Pronk

发明人： Xiaoming Zhou ,  Paul Marcel Carl Lemmens ,  Alphons Antonius Maria Lambertus Bruekers ,  Andrew Alexander Tokmakoff ,  Evelijne Machteld Hart De Ruijter-Bekker ,  Serverius Petrus Paulus Pronk

IPC分类号： G06T13/00 ,  G06F3/033

CPC分类号： G09B11/00 ,  G06T13/205 ,  G06T13/40

摘要： The invention relates to a method for modifying a representation based upon a user instruction and a system for producing a modified representation by said method. Conventional drawing systems, such as pen and paper and writing tablets, require a reasonable degree of drawing skill which not all users possess. Additionally, these conventional systems produce static drawings. The method of the invention comprises receiving a representation from a first user, associating the representation with an input object classification, receiving an instruction from a second user, associating the instruction with an animation classification, determining a modification of the representation using the input object classification and the animation classification, and modifying the representation using the modification. When the first user provides a representation of something, for example a character in a story, it is identified to a certain degree by associating it with an object classification. In other words, the best possible match is determined. As the second user imagines a story involving the representation, dynamic elements of the story are exhibited in one or more communication forms such as writing, speech, gestures, facial expressions. By deriving an instruction from these signals, the representation may be modified, or animated, to illustrate the dynamic element in the story. This improves the feedback to the users, and increases the enjoyment of the users.

摘要翻译： 本发明涉及一种用于基于用户指令修改表示的方法和用于通过所述方法产生修改表示的系统。 传统的绘图系统，如笔和纸和书写片，需要合理的绘图技能，而不是所有用户都拥有。 另外，这些常规系统产生静态图。 本发明的方法包括从第一用户接收表示，将表示与输入对象分类相关联，从第二用户接收指令，将指令与动画分类相关联，使用输入对象分类来确定表示的修改 和动画分类，并使用修改修改表示。 当第一个用户提供某种东西的表示时，例如故事中的角色，通过将其与对象分类相关联来确定它在一定程度上。 换句话说，确定最佳匹配。 作为第二个用户想象一个涉及表示的故事，故事的动态元素以一种或多种通信形式展现，如写作，言语，手势，面部表情。 通过从这些信号导出指令，可以修改或动画表示以说明故事中的动态元素。 这提高了对用户的反馈，并增加了用户的享受。

公开(公告)号：US07827459B1

公开(公告)日：2010-11-02

申请号：US11651314

申请日：2007-01-08

申请人： Xiaoming Zhou ,  John S. Baras

发明人： Xiaoming Zhou ,  John S. Baras

IPC分类号： H04L1/18

CPC分类号： H04L1/1812 ,  H04L1/1671 ,  H04L1/1854

摘要： The present invention relates to an improved communications protocol which increases the efficiency of transmission in return channels on a multi-channel slotted Alohas system by incorporating advanced error correction algorithms, selective retransmission protocols and the use of reserved channels to satisfy the retransmission requests.

摘要翻译： 本发明涉及一种改进的通信协议，其通过结合先进的纠错算法，选择性重传协议以及使用保留信道来满足重传请求，从而提高多信道时隙阿罗哈斯系统上返回信道的传输效率。