ALPHA-AMYLASE MUTANTS
    45.
    发明申请

    公开(公告)号:US20160222365A1

    公开(公告)日:2016-08-04

    申请号:US15012229

    申请日:2016-02-01

    申请人: NOVOZYMES A/S

    IPC分类号: C12N9/28

    摘要: The invention relates to a variant of a parent Termamyl-like α-amylase, which exhibits an alteration in at least one of the following properties relative to said parent α-amylase: i) improved pH stability at a pH from 8 to 10.5; and/or ii) improved Ca2+ stability at pH 8 to 10.5, and/or iii) increased specific activity at temperatures from 10 to 60° C.

    摘要翻译: 本发明涉及相对于所述亲本α-淀粉酶显示出至少一种以下特性的母体类戊酰样α-淀粉酶的变体:i)在8至10.5的pH下改善的pH稳定性; 和/或ii)在pH8至10.5时提高的Ca 2+稳定性,和/或iii)在10至60℃的温度下提高比活性。

    ALPHA-AMYLASE VARIANTS WITH ALTERED PROPERTIES
    46.
    发明申请
    ALPHA-AMYLASE VARIANTS WITH ALTERED PROPERTIES 审中-公开
    具有改性性质的ALPHA-AMYLASE变体

    公开(公告)号:US20160053244A1

    公开(公告)日:2016-02-25

    申请号:US14755048

    申请日:2015-06-30

    申请人: NOVOZYMES A/S

    IPC分类号: C12N9/28

    摘要: The present invention relates to variants (mutants) of polypeptides, in particular Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits an alteration in at least one of the following properties relative to said parent alpha-amylase: substrate specificity, substrate binding, substrate cleavage pattern, thermal stability, pH/activity profile, pH/stability profile, stability towards oxidation, Ca2+ dependency, specific activity, in particular laundry and dish-wash applications.

    摘要翻译: 本发明涉及多肽的变体(突变体),特别是类戊酰样α-淀粉酶,该变体具有α-淀粉酶活性并且相对于所述亲本α-淀粉酶在至少一个以下性质中具有改变:底物特异性 ,底物结合,底物切割模式,热稳定性,pH /活性分布,pH /稳定性分布,对氧化的稳定性,Ca 2+依赖性,比活性,特别是洗衣和洗碗应用。

    Phytase Variants
    48.
    发明申请
    Phytase Variants 审中-公开
    植酸酶变体

    公开(公告)号:US20150024084A1

    公开(公告)日:2015-01-22

    申请号:US14504517

    申请日:2014-10-02

    申请人: NOVOZYMES A/S

    IPC分类号: A23K1/165 C12N9/16

    摘要: The present invention relates to a phytase which has at least 74% identity to a phytase derived from Citrobacter braakii and comprises at least one alteration as compared to this phytase. These phytase variants have amended, preferably improved, properties, such as thermostability, temperature profile, pH profile, specific activity, performance in animal feed, reduced protease sensitiliby, and/or an amended glycosylation pattern. The invention also relates to DNA encoding these phytases, methods of their production, as well as the use thereof, e.g., in animal feed and animal feed additives.

    摘要翻译: 本发明涉及一种植酸酶,其与来自柠檬酸杆菌的植酸酶具有至少74%的同一性,并且与该植酸酶相比包含至少一个改变。 这些植酸酶变体具有修饰,优选改进的性质,例如热稳定性,温度曲线,pH曲线,比活性,动物饲料中的性能,降低的蛋白酶敏感性和/或修饰的糖基化模式。 本发明还涉及编码这些植酸酶的DNA,其生产方法及其用途,例如在动物饲料和动物饲料添加剂中。