公开(公告)号：US06467862B1

公开(公告)日：2002-10-22

申请号：US09163765

申请日：1998-09-30

申请人： Eric Peeters ,  Jaan Noolandi ,  Raj B. Apte ,  Philip D. Floyd ,  Jonathan A. Small ,  Gregory J. Kovacs ,  Meng H. Lean ,  Armin R. Volkel ,  Steven B. Bolte ,  An-Chang Shi ,  Frederick J. Endicott ,  Gregory B. Anderson ,  Dan A. Hays ,  Joel A. Kubby ,  Warren B. Jackson

发明人： Eric Peeters ,  Jaan Noolandi ,  Raj B. Apte ,  Philip D. Floyd ,  Jonathan A. Small ,  Gregory J. Kovacs ,  Meng H. Lean ,  Armin R. Volkel ,  Steven B. Bolte ,  An-Chang Shi ,  Frederick J. Endicott ,  Gregory B. Anderson ,  Dan A. Hays ,  Joel A. Kubby ,  Warren B. Jackson

IPC分类号： B41J300

CPC分类号： B41J2/14 ,  B41J2/01 ,  B41J2/211 ,  B41J2202/02

摘要： A cartridge is disclosed for use in a marking apparatus in which a propellant stream is passed through a channel and directed toward a substrate. Marking material, such as ink, toner, etc., is controllably introduced into the propellant stream and imparted with sufficient kinetic energy thereby to be made incident upon a substrate. A multiplicity of channels for directing the propellant and marking material allow for high throughput, high resolution marking. Multiple marking materials may be introduced into the channel and mixed therein prior to being made incident on the substrate, or mixed or superimposed on the substrate without re-registration. The cartridge may be replacably attached to the marking apparatus, and may contain one or more marking materials, propellant, etc.

摘要翻译： 公开了一种用于标记装置的盒，其中推进剂流通过通道并指向衬底。 诸如油墨，调色剂等的标记材料被可控地引入推进剂流中并且赋予足够的动能从而被入射到基底上。 用于引导推进剂和标记材料的多个通道允许高通量，高分辨率标记。 可以将多种标记材料引入通道中并在其入射到基板之前混合，或者混合或叠加在基板上而不重新配准。 墨盒可以可替代地附接到打标设备，并且可以包含一种或多种标记材料，推进剂等。

公开(公告)号：US06454384B1

公开(公告)日：2002-09-24

申请号：US09163924

申请日：1998-09-30

申请人： Eric Peeters ,  Jaan Noolandi ,  Raj B. Apte ,  Philip D. Floyd ,  Jonathan A. Small ,  Gregory J. Kovacs ,  Meng H. Lean ,  Armin R. Volkel ,  Steven B. Bolte ,  An-Chang Shi ,  Frederick J. Endicott ,  Gregory B. Anderson ,  Dan A. Hays ,  Joel A. Kubby ,  Warren B. Jackson ,  Andrew A. Berlin ,  G. A. Neville Connell

发明人： Eric Peeters ,  Jaan Noolandi ,  Raj B. Apte ,  Philip D. Floyd ,  Jonathan A. Small ,  Gregory J. Kovacs ,  Meng H. Lean ,  Armin R. Volkel ,  Steven B. Bolte ,  An-Chang Shi ,  Frederick J. Endicott ,  Gregory B. Anderson ,  Dan A. Hays ,  Joel A. Kubby ,  Warren B. Jackson ,  Andrew A. Berlin ,  G. A. Neville Connell

IPC分类号： B41J205

CPC分类号： B41J2/14 ,  B41J2/01 ,  B41J2/211 ,  B41J2202/02

摘要： A method of marking is disclosed in which a propellant stream is passed through a channel and directed toward a substrate. Liquid marking material, such as ink, is controllably introduced into the propellant stream and imparted with sufficient kinetic energy thereby to be made incident upon a substrate. A multiplicity of channels for directing the propellant and marking material allow for high throughput, high resolution marking. Multiple marking materials may be introduced into the channel and mixed therein prior to being made incident on the substrate, or mixed or superimposed on the substrate without registration. One example is a single-pass, full-color printer.

摘要翻译： 公开了一种标记方法，其中推进剂流通过通道并指向衬底。 诸如油墨的液体标记材料被可控地引入推进剂流中并且赋予足够的动能，从而使其入射到基底上。 用于引导推进剂和标记材料的多个通道允许高通量，高分辨率标记。 可以将多个标记材料引入通道中并在其入射到基板之前混合，或者混合或叠加在基板上而不进行配准。 一个例子是单程全彩色打印机。

公开(公告)号：US06454260B1

公开(公告)日：2002-09-24

申请号：US09730159

申请日：2000-12-05

申请人： Jaan Noolandi ,  David K. Biegelsen ,  Patrick C. P. Cheung ,  Andrew A. Berlin

发明人： Jaan Noolandi ,  David K. Biegelsen ,  Patrick C. P. Cheung ,  Andrew A. Berlin

IPC分类号： A63F736

CPC分类号： B65H29/245 ,  A63F7/06 ,  A63F7/066 ,  A63F7/3603 ,  B65H2406/1132 ,  B65H2406/14

摘要： An air jet game comprising an air jet conduiting member having a plurality of air jet outlets and a controller adapted to selectively control at least partially, the flow of air out of the air jet outlets in order to move an object located in an air flow path of the outlet in a desired direction.

摘要翻译： 一种喷气式飞机，包括具有多个空气喷射出口的空气喷射导管构件和适于选择性地至少部分地控制空气流出空气喷射出口的空气流的流量的控制器，以便移动位于空气流路 的出口。

公开(公告)号：US06416158B1

公开(公告)日：2002-07-09

申请号：US09407908

申请日：1999-09-29

申请人： Philip D. Floyd ,  Tuan Anh Vo ,  Kaiser H. Wong ,  Gregory B. Anderson ,  Eric Peeters ,  Jaan Noolandi ,  Meng H. Lean ,  Armin R. Volkel ,  John E. Northrup ,  Jurgen Daniel ,  G. A. Neville Connell

发明人： Philip D. Floyd ,  Tuan Anh Vo ,  Kaiser H. Wong ,  Gregory B. Anderson ,  Eric Peeters ,  Jaan Noolandi ,  Meng H. Lean ,  Armin R. Volkel ,  John E. Northrup ,  Jurgen Daniel ,  G. A. Neville Connell

IPC分类号： B41J2035

CPC分类号： B41J2/01 ,  B41J2/14 ,  B41J2/211 ,  B41J2202/02

摘要： A device for the transport and/or metering of marking material includes a plurality of phased electrodes, for example formed on a substrate. An electrostatic traveling wave may be generated along the electrodes to sequentially attract particles of marking material, and thereby transport them to a desired location. The electrodes may be formed in a planar structure. A matrix interconnection scheme allows for reduced lead count.

摘要翻译： 用于运输和/或计量标记材料的装置包括多个相控电极，例如形成在基底上。 可以沿着电极产生静电行波，以顺序地吸引标记材料的颗粒，从而将它们运送到期望的位置。 电极可以形成为平面结构。 矩阵互连方案允许减少引线数。

公开(公告)号：US06340216B1

公开(公告)日：2002-01-22

申请号：US09164250

申请日：1998-09-30

申请人： Eric Peeters ,  Jaan Noolandi ,  Raj B. Apte ,  Philip D. Floyd ,  Jonathan A. Small ,  Gregory J. Kovacs ,  Meng H. Lean ,  Armin R. Volkel ,  Steven B. Bolte ,  An-Chang Shi ,  Frederick J. Endicott ,  Gregory B. Anderson ,  Dan A. Hays ,  Joel A. Kubby ,  Warren B. Jackson ,  Karen A. Moffat ,  T. Brian McAneney ,  Richard P. N. Veregin ,  Maria N. V. McDougall ,  Danielle C. Boils ,  Paul D. Szabo

发明人： Eric Peeters ,  Jaan Noolandi ,  Raj B. Apte ,  Philip D. Floyd ,  Jonathan A. Small ,  Gregory J. Kovacs ,  Meng H. Lean ,  Armin R. Volkel ,  Steven B. Bolte ,  An-Chang Shi ,  Frederick J. Endicott ,  Gregory B. Anderson ,  Dan A. Hays ,  Joel A. Kubby ,  Warren B. Jackson ,  Karen A. Moffat ,  T. Brian McAneney ,  Richard P. N. Veregin ,  Maria N. V. McDougall ,  Danielle C. Boils ,  Paul D. Szabo

IPC分类号： B41J2015

CPC分类号： B41J2/211 ,  B41J2/01 ,  B41J2/14 ,  B41J2/14008 ,  B41J2202/02

摘要： An apparatus for treating a substrate is disclosed in which a propellant stream is passed through a channel and directed toward a substrate. Substrate pre-marking or post-marking treatment material is controllably introduced into the propellant stream and imparted with sufficient kinetic energy thereby to be made incident upon a substrate. A multiplicity of channels for directing the propellant and treatment material allow for high throughput, high resolution in-situ treatment. Marking materials and treatment materials may be introduced into the channel and mixed therein prior to being made incident on the substrate, or mixed or superimposed on the substrate without registration. One example is a single-pass, full-color printer.

摘要翻译： 公开了一种用于处理基底的装置，其中推进剂流通过通道并指向基底。 将基板预标记或后标记处理材料可控地引入推进剂流中并赋予足够的动能，从而使其入射到基底上。 用于引导推进剂和处理材料的多个通道允许高产量，高分辨率原位处理。 可以将标记材料和处理材料引入通道并在其入射到基板之前混合，或者混合或叠加在基板上而不进行配准。 一个例子是单程全彩色打印机。

公开(公告)号：US5788749A

公开(公告)日：1998-08-04

申请号：US799946

申请日：1997-02-14

申请人： Marcel P. Breton ,  Susanne Birkel ,  Carl P. Tripp ,  Jaan Noolandi

发明人： Marcel P. Breton ,  Susanne Birkel ,  Carl P. Tripp ,  Jaan Noolandi

IPC分类号： C09D11/02 ,  C09D11/00 ,  C09D11/06

CPC分类号： C09D11/322

摘要： Disclosed is an ink composition which comprises an aqueous liquid vehicle, a pigment, and a vesicle-forming lipid, wherein vesicles of the lipid are present in the ink.

摘要翻译： 公开了一种油墨组合物，其包含水性液体载体，颜料和形成小泡的脂质，其中所述脂质的小泡存在于所述油墨中。

公开(公告)号：US20180318610A1

公开(公告)日：2018-11-08

申请号：US15965868

申请日：2018-04-28

申请人： Jaan Noolandi

发明人： Jaan Noolandi

IPC分类号： A61N7/00

CPC分类号： A61N7/00 ,  A61N2007/0021

摘要： A method is provided to disrupt tau entanglements and amyloid plaques in a person's brain. An ultrasound profile generated by an ultrasound device is applied to the person's brain. The generated ultrasound profile is characterized by a frequency between 20-100 kHz, a pulse power greater than 10 W/cm−2, a pulse length greater than 1 microsecond, and an interval between pulses greater than 1 millisecond. The method is performed without intravenous injection of microbubbles to the person or use of preformed microbubbles.

公开(公告)号：US08070956B2

公开(公告)日：2011-12-06

申请号：US12082094

申请日：2008-04-07

申请人： Mark Peterman ,  Jaan Noolandi

发明人： Mark Peterman ,  Jaan Noolandi

IPC分类号： B01D15/08 ,  B01D57/02 ,  C02F1/28

CPC分类号： B01D15/38

摘要： A method of using electrokinetics for separating particles in a buffer solution is provided, where a chromatographic column is provided having a non-uniform internal longitudinal cross-section. At least one main inlet for inputting solution and at least one main outlet for outputting solution are provided. At least one sample inlet and at least one sample outlet are provided. The particle is introduced to the column from the sample inlet and fractionated samples are eluted from the sample outlet, where quality control and further analysis are enabled. An electric field is applied to the solution in the column to generate a charged double layer at a solid-liquid interface within the column. The electric filed moves ions within the double layer, and a non-uniform velocity profile is induced to the buffer solution. The moving ions carry the particles along the column and the particles are separated according to size or charge.

摘要翻译： 提供了一种使用电动力学分离缓冲溶液中的颗粒的方法，其中提供了具有不均匀内部纵向横截面的色谱柱。 提供至少一个用于输入溶液的主入口和用于输出溶液的至少一个主出口。 提供至少一个样品入口和至少一个样品出口。 将颗粒从样品入口引入柱中，分馏的样品从样品出口洗脱出来，其中进行质量控制和进一步分析。 将电场施加到柱中的溶液中，以在柱内的固 - 液界面产生带电双层。 电场在双层内移动离子，并且向缓冲溶液中引入不均匀的速度分布。 移动的离子沿着柱子携带颗粒，并且颗粒根据尺寸或电荷分离。

公开(公告)号：US20090314861A1

公开(公告)日：2009-12-24

申请号：US12214552

申请日：2008-06-18

申请人： Jaan Noolandi

发明人： Jaan Noolandi

IPC分类号： B05B5/00

CPC分类号： B05B5/0255

摘要： Fluid ejection using multiple voltage pulses and removable well modules is provided. Ejection of an electrically conductive fluid is accomplished by the application of two or more high voltage pulses. The high voltage pulses are applied across a conducting nozzle for transporting the fluid and a grounded conducting ring positioned below the nozzle. Ejected fluid droplets fall through the center of the conducting ring and onto a substrate. The presence and approximate size of the ejected droplets can be sensed and used for feedback for the high voltage pulses. The conductive fluids are stored in well modules that are not permanently attached to a well plate. Each removable well module includes a conducting nozzle and can include valves and a memory chip. Control circuits are also provided to independently control the high voltage pulses applied to the individual well modules.

摘要翻译： 提供使用多个电压脉冲和可移除的井模块的流体喷射。 通过施加两个或多个高电压脉冲来实现导电流体的喷射。 高电压脉冲施加在用于输送流体的导电喷嘴和位于喷嘴下方的接地导电环。 弹出的液滴从导电环的中心落到基板上。 喷射的液滴的存在和大致尺寸可被感测并用于高电压脉冲的反馈。 导电流体存储在不永久地附着到孔板的孔模块中。 每个可移除的井模块包括导电喷嘴，并且可以包括阀和存储芯片。 还提供控制电路以独立地控制施加到各个井模块的高电压脉冲。

公开(公告)号：US20060287721A1

公开(公告)日：2006-12-21

申请号：US11409218

申请日：2006-04-20

申请人： David Myung ,  Christopher Ta ,  Nabeel Farooqui ,  Curtis Frank ,  Won-Gun Koh ,  Jungmin Ko ,  Jaan Noolandi ,  Michael Carrasco

发明人： David Myung ,  Christopher Ta ,  Nabeel Farooqui ,  Curtis Frank ,  Won-Gun Koh ,  Jungmin Ko ,  Jaan Noolandi ,  Michael Carrasco

IPC分类号： A61F2/14

CPC分类号： A61F2/142 ,  A61F2/15 ,  A61K35/12

摘要： The present invention provides an artificial corneal implant having an optically clear central core and a porous, hydrophilic, biocompatible skirt peripheral to the central core. In one embodiment, the central core is made of an interpenetrating double network hydrogel and the skirt is made of poly(2-hydroxyethyl acrylate) (PHEA). In another embodiment, both the central core and the skirt are made of interpenetrating double network hydrogels. The artificial corneal implant may also have an interdiffusion zone in which the skirt component is interpenetrated with the core component, or vice versa. In a preferred embodiment, biomolecules are linked to the skirt, central core or both. These biomolecules may be any type of biomolecule, but are preferably biomolecules that support epithelial and/or fibroblast cell survival and growth. Preferably, the biomolecules are linked in a spatially selective manner. The present invention also provides a method of making an artificial corneal implant using photolithography.

摘要翻译： 本发明提供了一种人造角膜植入物，其具有光学透明的中心纤芯和围绕中心纤芯的多孔，亲水的，生物相容的裙部。 在一个实施方案中，中心芯由互穿双网络水凝胶制成，裙部由聚（丙烯酸2-羟乙酯）（PHEA）制成。 在另一个实施例中，中心芯和裙部均由互穿双网络水凝胶制成。 人造角膜植入物也可以具有相互扩散区​​域，其中裙部组件与芯部件互穿，反之亦然。 在优选的实施方案中，生物分子连接到裙部，中心芯或两者。 这些生物分子可以是任何类型的生物分子，但优选支持上皮和/或成纤维细胞存活和生长的生物分子。 优选地，生物分子以空间选择性方式连接。 本发明还提供了使用光刻法制造人造角膜植入物的方法。