公开(公告)号：US20140364398A1

公开(公告)日：2014-12-11

申请号：US14469657

申请日：2014-08-27

Applicant: Pfizer Inc.

Inventor： Matthew Frank Brown ,  Anthony Marfat ,  Michael Joseph Melnick ,  Usa Reilly

IPC: C07C317/50 ,  C07F9/09 ,  C07D239/26 ,  C07D231/12 ,  C07D233/36 ,  C07D213/30 ,  C07D213/56 ,  C07D261/08

CPC classification number: C07C317/50 ,  C07C317/44 ,  C07C317/46 ,  C07C317/48 ,  C07C323/65 ,  C07C2601/02 ,  C07C2601/08 ,  C07C2601/16 ,  C07C2601/18 ,  C07D213/30 ,  C07D213/56 ,  C07D215/06 ,  C07D231/12 ,  C07D231/56 ,  C07D233/36 ,  C07D239/26 ,  C07D261/08 ,  C07D263/08 ,  C07D263/20 ,  C07D295/03 ,  C07D335/02 ,  C07F9/09 ,  C07F9/12

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.

Abstract translation: 本发明涉及一类新的异羟肟酸衍生物，它们用作LpxC抑制剂，更具体地说是它们用于治疗细菌感染的用途。

公开(公告)号：US08779148B2

公开(公告)日：2014-07-15

申请号：US14068956

申请日：2013-10-31

Applicant: Pfizer Inc.

Inventor： Usa Reilly ,  Michael Joseph Melnick ,  Matthew Frank Brown ,  Mark Stephen Plummer ,  Justin Ian Montgomery ,  Ye Che ,  Loren Michael Price

IPC: A61K31/44 ,  C07D211/72 ,  C07D413/10 ,  C07D417/12 ,  C07D213/64 ,  C07D405/12 ,  C07D213/69 ,  C07D405/04 ,  C07D401/04 ,  C07D401/10

CPC classification number: C07D405/04 ,  C07D213/64 ,  C07D213/69 ,  C07D401/04 ,  C07D401/10 ,  C07D405/12 ,  C07D413/10 ,  C07D417/12

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

公开(公告)号：US20140128363A1

公开(公告)日：2014-05-08

申请号：US14154239

申请日：2014-01-14

Applicant: Pfizer Inc.

Inventor： Matthew Frank Brown ,  Ye Che ,  Anthony Marfat ,  Michael Joseph Melnick ,  Justin Ian Montgomery ,  Usa Reilly

IPC: C07D413/10 ,  C07D211/86 ,  C07D401/04 ,  C07D403/04 ,  C07D401/10 ,  C07D401/12

CPC classification number: A61K31/4412 ,  A61K31/4439 ,  C07D211/86 ,  C07D213/64 ,  C07D401/04 ,  C07D401/08 ,  C07D401/10 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D405/04 ,  C07D405/10 ,  C07D409/04 ,  C07D413/10 ,  C07D413/12 ,  C07D417/04 ,  C07D417/10 ,  C07D417/12 ,  Y02A50/473

Abstract: The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.