Biosensing systems and methods using a FET

    公开(公告)号:US10739305B1

    公开(公告)日:2020-08-11

    申请号:US16669621

    申请日:2019-10-31

    IPC分类号: G01N27/414

    摘要: Systems and methods for sensing analytes using an extended gate field effect transistor (EGFET) are provided. A biosensing system can utilize a biodetection layer on a substrate, which can be coupled to a field effect transistor (FET). The coupling can be such that the gate of the field effect transistor is connected to the substrate having the biodetection layer thereon. The functionalized substrate can include a well-defined area that can hold a specific, pre-determined volume of fluid on top of it. An external electrode can be dipped in the fluid and can then be connected to a power source supplying a gate voltage. The presence or concentration of the target analyte in the fluid can be determined based on the source-drain characteristics of the FET.

    Ion trap with notched ring electrode

    公开(公告)号:US10699893B1

    公开(公告)日:2020-06-30

    申请号:US16722971

    申请日:2019-12-20

    IPC分类号: H01J49/42 H01J49/00

    摘要: Cylindrical ion traps (CITs) that can be used for molecular sample identification, as well as systems and methods using the same, are provided. A CIT can utilize a notched ring electrode having an inner diameter that increases as a first end of the CIT is approached from the center of the CIT or from a second end of the CIT. The first end can be the one positioned closer to the ion detector than is the second end, which can be positioned closer to the ion source than is the first end.

    SENSOR FOR DETECTION OF ACETONE
    47.
    发明申请

    公开(公告)号:US20200103366A1

    公开(公告)日:2020-04-02

    申请号:US16582230

    申请日:2019-09-25

    摘要: Continuous monitoring of acetone is a challenge using related art sensing methods. Though real-time detection of acetone from different biofluids is promising, signal interference from other biomarkers remains an issue. A minor fluctuation of the signals in the micro-ampere range can cause substantial overlapping in linear/polynomial calibration fittings. To address the above in non-invasive detection, principal component analysis (PCA) can be used to generate specific patterns for different concentration points of acetone in the subspace. This results in improvement of the problem of overlapping of the signals between two different concentration points of the data sets while eliminating dimensionality and redundancy of data variables. An algorithm following PCA can be incorporated in a microcontroller of a sensor, resulting in a functional wearable acetone sensor. Acetone in the physiological range (0.5 ppm to 4 ppm) can be detected with such a sensor.

    MEMS microgenerator cell and microgenerator cell array
    50.
    发明授权
    MEMS microgenerator cell and microgenerator cell array 有权
    MEMS微发电机和微发电机阵列

    公开(公告)号:US08541910B1

    公开(公告)日:2013-09-24

    申请号:US11162697

    申请日:2005-09-20

    IPC分类号: H02K44/00

    CPC分类号: H02K44/08 H02N3/00

    摘要: A microelectrical mechanical system (MEMS) microgenerator cell and array is disclosed. The MEMS microgenerator cell of the present invention is effective in the conversion of thermal energy to electrical energy. In accordance with the present invention, an explosive material is loaded into a chamber. A diaphragm seals the chamber, containing a plasma material. The explosive material is subsequently heated to its ignition temperature thereby raising the pressure in the chamber until the diaphragm ruptures. The rupture of the diaphragm results in the flow of plasma out of the chamber. Upon exiting the chamber, the plasma is forced to flow between two parallel rectangular electrodes. A magnetic field is applied in a direction orthogonal to both the plasma flow and the electrodes, thereby generating an electromagnetic field sufficient to a power source for MEMS devices.

    摘要翻译: 公开了一种微电机械系统(MEMS)微发电机单元和阵列。 本发明的MEMS微发电机单元有效地将热能转换成电能。 根据本发明,将爆炸性材料装入室中。 隔膜密封腔室,包含等离子体材料。 随后将爆炸性材料加热至其着火温度,从而提高腔室内的压力,直到隔膜破裂为止。 隔膜的破裂导致等离子体流出室。 离开室后,迫使等离子体在两个平行的矩形电极之间流动。 在与等离子体流和电极两者正交的方向上施加磁场,从而产生足以用于MEMS器件的电源的电磁场。