公开(公告)号：US20230045752A1

公开(公告)日：2023-02-09

申请号：US17880866

申请日：2022-08-04

申请人： Nan Chen ,  He Zhao ,  Yunshui Chen

发明人： Nan Chen ,  He Zhao ,  Yunshui Chen

IPC分类号： H05K7/20

摘要： A system and method for cooling electronic equipment having a power supply unit separate from the equipment, sprayers that spray a dielectric liquid coolant on the top of the equipment lengthwise along one or more fins of one or more heat sinks on the equipment, a reservoir, connectors, and pumps for pumping the liquid coolant from the reservoir and through the sprayer, and an external housing.

公开(公告)号：US20220418155A1

公开(公告)日：2022-12-29

申请号：US17487000

申请日：2021-09-28

申请人： Nan Chen ,  He Zhao ,  Yunshui Chen

发明人： Nan Chen ,  He Zhao ,  Yunshui Chen

IPC分类号： H05K7/20

摘要： A device including a microchannel heat sink having a first layer circle A and circle B fins and a second layer circle A and circle B fins, wherein circle A fins includes a plurality of outer ring fins and circle B fins includes a plurality of inner ring fins; a cover assembly, in which the cover assembly includes adaptors, a liquid channel, a vapor channel, and a TRV chamber; a thermal regulation valve (TRV), wherein the thermal regulation valve (TRV) is configured to enable dynamic responses for temperature control in the microchannel heat sink; and a temperature sensing mechanism, in which the temperature sensing mechanism is configured to be operable for detecting temperature variations and converting the temperature variations to pressure variations.

公开(公告)号：US11022700B2

公开(公告)日：2021-06-01

申请号：US16221946

申请日：2018-12-17

申请人： Shanghai Astronomical Observatory, Chinese Academy of Sciences ,  Jianhua Zhou ,  He Zhao ,  ComNav Technology Ltd.

发明人： Junping Chen ,  Jianhua Zhou ,  Yongquan Wang ,  He Zhao

IPC分类号： G01S19/41 ,  G01S19/43 ,  G01S19/13

摘要： The present application provides a method for navigation and positioning of a receiver, including: receiving basic broadcast messages and correction parameters of a plurality of satellites, and establishing a pseudorange observation equation and a carrier-phase observation equation corresponding to each of satellites respectively; correcting the pseudorange observation equation and the carrier-phase observation equation using the received correction parameters to obtain the corrected pseudorange observation equation and the corrected carrier-phase observation equation; constructing a first observation according to the corrected pseudorange observation equation and the corrected carrier-phase observation equation; constructing a second observation according to the corrected pseudorange observation equation and the corrected carrier-phase observation equation; and jointly solving the obtained first observations and second observations of the plurality of satellites to obtain anoperation result of user positioning.

公开(公告)号：US20150344897A1

公开(公告)日：2015-12-03

申请号：US14422661

申请日：2012-09-14

申请人： Haibo Wang ,  Fushuang Dong ,  Mengyu Lv ,  Yanmin Zhang ,  Zhiheng Ren ,  Fan Yang ,  Xinchao Liang ,  Wenbo Zuo ,  Xueping Shi ,  Huanhuan Zhang ,  Yiping Gao ,  He Zhao ,  Xian Xu ,  Guozhong Sun ,  Jianfang Chai ,  Yongwei Liu ,  Jinyong Zhu ,  Qiufen Han ,  Qiang Zhang ,  Huijie Ma ,  Zhanwu Wang ,  Junfeng Guan

发明人： Haibo Wang ,  Fushuang Dong ,  Mengyu Lv ,  Yanmin Zhang ,  Zhiheng Ren ,  Fan Yang ,  Xinchao Liang ,  Wenbo Zuo ,  Xueping Shi ,  Huanhuan Zhang ,  Yiping Gao ,  He Zhao ,  Xian Xu ,  Guozhong Sun ,  Jianfang Chai ,  Yongwei Liu ,  Jinyong Zhu ,  Qiufen Han ,  Qiang Zhang ,  Huijie Ma ,  Zhanwu Wang ,  Junfeng Guan

IPC分类号： C12N15/82

CPC分类号： C12N15/8205 ,  C12N15/8207

摘要： The present invention is a method of shoot apical meristem transformation for monocot plant via sufficient and micro wounding (SMW). The technical process includes: expose the apical meristem by removing the coleoptile away when the shoot grows to 0.2-2 cm after 1-2 days of seed germination; make sufficient and micro wounding transformation to the apical meristem by stabbing and brushing for 2-3 times using the SMW brush having 100-5000 bristles which is 4-20 μm in diameter for each one and 0.5-3 mm in exposed length, and dipped with the Agrobacterium tumefaciens containing binary vector harboring exogenous genes; develop the treated meristems directly to normal plants after co-cultivation; promote the plants to develop big spikes and set more seeds; harvest the seeds of T0 plants separately; detect and identify the transformation results in T1 generation which is bred from each individual T0 plant. The advantages of the invention are independent of tissue culture, unlimited in genotype, unnecessary to carry resistant marker, simple and large scale to perform, and applicable to all monocot plants which can set seeds. The transformation efficiencies for wheat, rice and maize using this method are 49%, 66.3%, and 100%, respectively.

摘要翻译： 本发明是通过足够和微伤（SMW）的单子叶植物的茎顶分生组织转化的方法。 技术过程包括：通过在种子发芽1-2天后枝条生长至0.2-2厘米时，通过去除胚芽鞘来揭开顶端分生组织; 使用具有直径为4-20μm，暴露长度为0.5-3mm的直径为4-20μm的100-5000个刷毛的SMW刷，通过刺入和刷刷2-3次来对顶端分生组织进行充分和微小的伤口转化，并浸渍 含有包含外源基因的二元载体的根癌农杆菌; 共培养后将经处理的分生组织直接发育至正常植物; 促进植物发展大穗，种植更多种子; 分别收获T0植物的种子; 检测和识别从每个T0植物繁殖的T1代转化结果。 本发明的优点独立于组织培养，基因型无限，不需携带抗性标记，简单大规模进行，适用于可以设置种子的所有单子叶植物。 使用该方法对小麦，水稻和玉米的转化效率分别为49％，66.3％和100％。

公开(公告)号：US09067949B2

公开(公告)日：2015-06-30

申请号：US13352864

申请日：2012-01-18

申请人： Peter R. Guzzo ,  Alan J. Henderson ,  Matthew Isherwood ,  Chong Yew Lee ,  Animesh Ghosh ,  He Zhao

发明人： Peter R. Guzzo ,  Alan J. Henderson ,  Matthew Isherwood ,  Chong Yew Lee ,  Animesh Ghosh ,  He Zhao

IPC分类号： C07D491/048 ,  C07D307/91 ,  C07D491/18 ,  C07D491/08

CPC分类号： C07D491/048 ,  C07D307/91 ,  C07D491/08 ,  C07D491/18

摘要： The present invention relates to benzofuro[3,2-c]pyridine and azepine analogs as serotonin sub-type 6 (5-HT6) modulators, pharmaceutical compositions including these compounds, methods of preparation, and use thereof. These compounds are useful in the treatment of central nervous system disorders including obesity, metabolic syndrome, cognition, schizophrenia, attention deficit hyperactivity disorder, bipolar disorder, rare and orphan diseases, and sleep disorders. The subject compounds have the structure of formula (I) with the substituents being described herein.

摘要翻译： 本发明涉及作为血清素亚型6（5-HT6）调节剂的苯并呋喃并[3,2-c]吡啶和吖庚因类似物，包括这些化合物的药物组合物，其制备方法和用途。 这些化合物可用于治疗中枢神经系统疾病，包括肥胖，代谢综合征，认知，精神分裂症，注意缺陷多动障碍，双相情感障碍，罕见和孤儿疾病以及睡眠障碍。 本发明化合物具有式（I）的结构，其中取代基在本文中描述。

公开(公告)号：US20100216763A1

公开(公告)日：2010-08-26

申请号：US12516480

申请日：2007-11-27

申请人： Alan J. Hutchison ,  Hongbin Li ,  Jianmin Mao ,  David J. Wustrow ,  Jun Yuan ,  He Zhao

发明人： Alan J. Hutchison ,  Hongbin Li ,  Jianmin Mao ,  David J. Wustrow ,  Jun Yuan ,  He Zhao

IPC分类号： A61K31/397 ,  C07D471/04 ,  A61K31/437 ,  C07D403/14 ,  A61K31/496 ,  C07D413/14 ,  A61K31/5377 ,  C07D223/04 ,  A61K31/55 ,  C07D221/20 ,  A61K31/438 ,  C07D295/15 ,  A61K31/4995 ,  C07D243/08 ,  A61K31/551 ,  C07D221/22 ,  A61K31/439 ,  C07D417/14 ,  A61K31/541 ,  C07D281/06 ,  A61K31/553 ,  A61P29/00 ,  A61P25/24 ,  A61P25/22 ,  A61P25/18

CPC分类号： C07D471/04 ,  C07D471/10 ,  C07D487/04 ,  C07D487/08 ,  C07D491/113 ,  C07D519/00

摘要： Heteroaryl amide derivatives are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

摘要翻译： 提供了以下分子式的杂芳酰胺衍生物：其中变量如本文所述。 这些化合物是可用于在体内或体外调节特异性受体活性的配体，并且特别可用于治疗与人类，驯养伴侣动物和家畜中的病理受体激活相关的病症。 还提供了使用这些化合物治疗这种病症的药物组合物和方法，以及使用这些配体进行受体定位研究的方法。

公开(公告)号：US20070007254A1

公开(公告)日：2007-01-11

申请号：US11178097

申请日：2005-07-08

申请人： Pei-Chung Wang ,  Xihua Zhao ,  He Zhao

发明人： Pei-Chung Wang ,  Xihua Zhao ,  He Zhao

IPC分类号： B23K26/00

CPC分类号： B23K28/02 ,  B23K11/061 ,  B23K11/11 ,  B23K26/244 ,  B23K2101/18

摘要： An improved fusion welding system having a heating unit and welding device is adapted for increasing the efficiency of welding a plurality of workpieces. The system preferably presents a single-sided process, and includes first and second electrode wheels operable to heat a portion of the workpieces to a minimum temperature, and a translatable laser cooperatively configured to form a continuous weld within the heated portion. The preferred system provides the advantages of laser welding, such as precision, while enabling weld production at lower laser power outputs or faster welding speeds than conventional laser welding systems.

摘要翻译： 具有加热单元和焊接装置的改进的熔焊系统适于提高焊接多个工件的效率。 该系统优选地呈现单面工艺，并且包括可操作以将一部分工件加热到最低温度的第一和第二电极轮以及协同地构造成在加热部分内形成连续焊接的可平移激光器。 优选的系统提供激光焊接的优点，例如精度，同时能够实现比传统激光焊接系统更低的激光功率输出的焊接生产或更快的焊接速度。

公开(公告)号：US20220418166A1

公开(公告)日：2022-12-29

申请号：US17360003

申请日：2021-06-28

申请人： Nan Chen ,  He Zhao ,  Yunshui Chen

发明人： Nan Chen ,  He Zhao ,  Yunshui Chen

IPC分类号： H05K7/20

摘要： A reverse-return parallel loop system is provided, including a cooling cycle comprised of a plurality of heat sinks, at least one heat exchanger, and at least one liquid pump to carry liquid coolant through the system. Each heat sink has a vapor inlet, a liquid inlet, a vapor outlet, and a liquid outlet. The liquid coolant is pumped into the heat sink through the liquid inlet where the coolant splits in to two streams, where one stream flows out of the liquid outlet towards the next heat sink downstream, and the other stream flows through the heat sink, and through the heat exchanger core to absorb heat from the heat sources and become at least partially vaporized by the heat. This stream then merges with vapor from other heat sinks upstream and flows out through the vapor outlet back towards the heat exchanger of the system.

公开(公告)号：US20220418160A1

公开(公告)日：2022-12-29

申请号：US17487013

申请日：2021-09-28

申请人： Nan Chen ,  He Zhao ,  Yunshui Chen

发明人： Nan Chen ,  He Zhao ,  Yunshui Chen

IPC分类号： H05K7/20

摘要： A system having a shell with a shell interior for housing a heat exchanger that is configured to be operable for heat transfer between a first fluid and a second fluid; a refrigerant inlet, wherein the first fluid passes from the refrigerant inlet to the shell interior for heat transfer; a refrigerant inlet manifold, wherein the refrigerant inlet manifold is configured to collect the first fluid from the refrigerant inlet for the heat transfer; a refrigerant outlet, the refrigerant outlet is configured to be operable for supplying the first fluid for electronic device cooling; a coolant inlet, wherein the second fluid flows from the coolant inlet and into the shell interior for the heat transfer; and a coolant outlet for discharging the second fluid out of the shell interior.

公开(公告)号：US20220206349A1

公开(公告)日：2022-06-30

申请号：US17431125

申请日：2020-12-29

申请人： He Zhao

发明人： He Zhao

IPC分类号： G02F1/1362 ,  G02F1/1343 ,  G02F1/1368 ,  H01L27/12

摘要： A display panel and a device are provided. The display panel includes a first substrate. The first substrate includes a first metal layer and a second metal layer. The first metal layer includes first metal portions. Each of the first metal portions includes a plurality of second sub-portions arranged along a second direction. The second metal layer includes a plurality of data lines. Each of the second sub-portions is disposed between two adjacent data lines. In a top view, the display panel includes a plurality of columns of pixels or a plurality of rows of pixels. Each of two sides of each of the columns of pixels is provided with one of the data lines.