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    METHOD AND SYSTEM FOR MICROBIOME ANALYSIS
    47.
    发明申请
    METHOD AND SYSTEM FOR MICROBIOME ANALYSIS 审中-公开

    公开(公告)号：US20170268046A1

    公开(公告)日：2017-09-21

    申请号：US15606709

    申请日：2017-05-26

    Applicant: uBiome, Inc.

    Inventor： Zachary Apte ,  Jessica Richman ,  Daniel Almonacid

    IPC: C12Q1/68 ,  G06F19/22

    CPC classification number: C12Q1/689 ,  C12Q1/6869 ,  C12Q1/6888 ,  G06F19/22

    Abstract: A method and system for analyzing a microbiome of an individual, comprising: providing a sampling kit to the individual at a location remote from the sample processing network, the sampling kit including a sample container having a lysing component and a sample preservation component and configured to receive a sample from a collection site of the individual; receiving the sample container with the sample from the collection site of the individual; generating a microbiome sequence dataset based upon sequencing nucleic acid content of a microorganism portion of the sample; identifying a set of microorganisms represented in the microorganism portion based upon performance of a mapping operation on portions of the microbiome sequence dataset; generating an analysis based upon a set of features related to the microorganism portion; and transmitting information derived from the analysis to the individual.

    METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS FOR CONDITIONS ASSOCIATED WITH MICROBIOME TAXONOMIC FEATURES
    48.
    发明申请
    METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS FOR CONDITIONS ASSOCIATED WITH MICROBIOME TAXONOMIC FEATURES 审中-公开
    用微生物衍生的诊断方法和系统和与微生物特征特征相关的条件的治疗方法

    公开(公告)号：US20170035346A1

    公开(公告)日：2017-02-09

    申请号：US15294526

    申请日：2016-10-14

    Applicant: uBiome, Inc.

    Inventor： Zachary Apte ,  Daniel Almonacid ,  Jessica Richman ,  Siavosh Rezvan Behbahani

    IPC: A61B5/00 ,  C12Q1/68 ,  G06F19/00

    CPC classification number: A61B5/4211 ,  A61B5/4233 ,  A61B5/4836 ,  A61B5/4839 ,  C12Q1/689 ,  C12Q2600/112 ,  G06F19/3418 ,  G16B40/00 ,  G16B50/00 ,  G16H20/00 ,  G16H40/63 ,  G16H50/20 ,  G16H50/50 ,  G16H50/70 ,  Y02A90/26

    Abstract: A method for at least one of characterizing, diagnosing, and treating a condition associated with microbiome taxonomic features in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

    Abstract translation: 用于表征，诊断和治疗与至少一个受试者中的微生物组分类特征有关的病症中的至少一种的方法，所述方法包括：从受试者群体接收聚集的一组生物样品; 为受试者群体生成微生物组合数据集和微生物群功能分集数据集中的至少一个; 基于从至少一个微生物组合数据集和微生物组合功能分集数据集中提取的特征产生条件的表征; 基于所述表征，产生被配置为校正所述状况的治疗模型; 并且在与受试者相关联的输出装置处，基于表征和治疗模型促进对受试者的治疗。

    METHOD AND SYSTEM FOR MICROBIOME-DERIVED CHARACTERIZATION, DIAGNOSTICS AND THERAPEUTICS FOR CUTANEOUS CONDITIONS
    49.
    发明申请
    METHOD AND SYSTEM FOR MICROBIOME-DERIVED CHARACTERIZATION, DIAGNOSTICS AND THERAPEUTICS FOR CUTANEOUS CONDITIONS 审中-公开
    微生物表达特征的诊断和治疗方法与系统

    公开(公告)号：US20160232319A1

    公开(公告)日：2016-08-11

    申请号：US15098153

    申请日：2016-04-13

    Applicant: uBiome, Inc.

    Inventor： Zachary Apte ,  Daniel Almonacid ,  Jessica Richman ,  Siavosh Rezvan Behbahani

    IPC: G06F19/00 ,  C12Q1/68

    CPC classification number: G16H50/20 ,  C12Q1/6874 ,  G06F19/3418 ,  G16B40/00 ,  G16B50/00 ,  G16B50/10 ,  G16H10/40 ,  G16H40/67 ,  Y02A90/26

    Abstract: A method for at least one of characterizing, diagnosing, and treating a cutaneous condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the cutaneous condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the cutaneous condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

    Abstract translation: 一种至少一种在至少一个受试者中表征，诊断和治疗皮肤病症的方法，所述方法包括：从受试者群体接收一组聚集的生物样品; 为受试者群体生成微生物组合数据集和微生物群功能分集数据集中的至少一个; 基于从至少一个微生物组合数据集和微生物组合功能分集数据集提取的特征产生皮肤病症的表征; 基于表征，产生构造成校正皮肤病症的治疗模型; 并且在与受试者相关联的输出装置处，基于表征和治疗模型促进对受试者的治疗。

    Method and system for microbiome-derived diagnostics and therapeutics
    50.
    发明授权
    Method and system for microbiome-derived diagnostics and therapeutics 有权

    公开(公告)号：US10380325B2

    公开(公告)日：2019-08-13

    申请号：US15606975

    申请日：2017-05-26

    Applicant: uBiome, Inc.

    Inventor： Zachary Apte ,  Jessica Richman ,  Daniel Almonacid

    IPC: G01N33/48 ,  G06F19/00 ,  C12Q1/68 ,  C12Q1/6883 ,  C12Q1/689 ,  G06F19/10 ,  G06F19/28 ,  G06F19/12 ,  G16H50/20 ,  G16H20/10 ,  G06G7/58

    Abstract: A method for diagnosing and treating an immune microbial dysfunction in a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the immune microbial dysfunction based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset, wherein the characterization is diagnostic of at least one of Crohn's disease, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), ulcerative colitis, and celiac disease; based upon the characterization, generating a therapy model configured to correct the immune microbial dysfunction; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

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