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    Systems and methods of optical coherence tomography with a multi-focal delay line
    41.
    发明授权
    Systems and methods of optical coherence tomography with a multi-focal delay line 有权

    公开(公告)号：US10085634B2

    公开(公告)日：2018-10-02

    申请号：US14968615

    申请日：2015-12-14

    申请人： AMO WaveFront Sciences, LLC

    发明人： Paul Pulaski ,  Daniel R. Neal ,  Thomas D. Raymond ,  Stephen W. Farrer ,  Daniel R. Hamrick ,  Richard J. Copland

    IPC分类号： A61B3/10 ,  A61B3/00 ,  G02B6/12

    摘要： An optical coherence tomography (OCT) system includes: a light source; a multi-focal delay line; and a light detector. The multi-focal delay line includes: a positive lens; and an optical switch configured to: receive a light from the light source; selectively direct the sample light to the positive lens via a selected one of a plurality of light interfaces each located a different distance from the focal plane of the positive lens; and direct the sample light to an object to be measured. The light detector is configured to receive return light returned from the object to be measured in response to the sample light, and to receive a reference light produced from the light from the light source, and in response thereto to detect at least one interference signal. An associated OCT method may be performed with the OCT system.

    Non-invasive refractive treatment using nanoparticles
    44.
    发明授权
    Non-invasive refractive treatment using nanoparticles 有权
    使用纳米粒子的非侵入性折射治疗

    公开(公告)号：US09241901B2

    公开(公告)日：2016-01-26

    申请号：US14199766

    申请日：2014-03-06

    申请人： AMO Wavefront Sciences, LLC.

    发明人： Thomas D. Raymond ,  Richard J. Copland

    IPC分类号： A61F9/007 ,  A61F9/01 ,  A61K9/00 ,  A61F2/14

    CPC分类号： A61F2/14 ,  A61F2/145 ,  A61F2/147 ,  A61F2/148 ,  A61F2250/0067 ,  A61K9/0048 ,  A61K9/0051 ,  A61K33/24

    摘要： Embodiments of this invention generally relate to systems and methods for optical treatment and more particularly to non-invasive refractive treatment method based on sub wavelength particle implantation. In an embodiment, a method for optical treatment identifies an optical aberration of an eye, determines a dopant delivery device configuration in response to the optical aberration of the eye, wherein the determined dopant delivery device is configured to impose a desired correction to the eye to mitigate the identified optical aberration of the eye by applying a doping pattern to the eye so as to locally change a refractive index of the eye.

    摘要翻译： 本发明的实施方案一般涉及用于光学治疗的系统和方法，更具体地涉及基于亚波长粒子植入的非侵入性折射治疗方法。 在一个实施例中，用于光学处理的方法识别眼睛的光学像差，响应于眼睛的光学像差确定掺杂剂递送装置配置，其中所确定的掺杂剂递送装置被配置为对眼睛施加期望的校正 通过向眼睛施加掺杂图案来局部改变眼睛的折射率来减轻所识别的眼睛的光学像差。

    OPTICAL MEASUREMENT SYSTEM AND METHOD WITH TARGET BRIGHTNESS LEVEL ADJUSTMENT
    45.
    发明申请
    OPTICAL MEASUREMENT SYSTEM AND METHOD WITH TARGET BRIGHTNESS LEVEL ADJUSTMENT 有权
    光学测量系统和方法与目标亮度水平调整

    公开(公告)号：US20160000316A1

    公开(公告)日：2016-01-07

    申请号：US14791175

    申请日：2015-07-02

    申请人： AMO WAVEFRONT SCIENCES, LLC

    发明人： RICHARD J. COPLAND ,  DAVID J. TANZER ,  THOMAS D. RAYMOND

    IPC分类号： A61B3/00 ,  A61B3/11 ,  A61B3/103

    CPC分类号： A61B3/0091 ,  A61B3/0025 ,  A61B3/0075 ,  A61B3/103 ,  A61B3/1035 ,  A61B3/112

    摘要： A system and method for measuring a characteristic of an eye of a subject receive data pertaining to the subject; assign the subject to an assigned age category based on the data pertaining to the subject; adjust a brightness level of a fixation target according to the assigned age category for the subject; provide the fixation target for a subject to view; and objectively measure at least one characteristic of the eye of the subject while the subject views the fixation target at the adjusted brightness level.

    摘要翻译： 用于测量对象的眼睛的特征的系统和方法接收与被摄体有关的数据; 根据与被摄体有关的数据，将受试者分配给指定的年龄类别; 根据被摄体的分配年龄类别调整固定目标的亮度水平; 提供受试者观察的固定目标; 并且客观地测量被摄体的眼睛的至少一个特征，同时被摄体以调节的亮度水平来观看固视目标。

    SYSTEM AND METHOD FOR OCULAR TOMOGRAPHY USING PLENOPTIC IMAGING
    47.
    发明申请
    SYSTEM AND METHOD FOR OCULAR TOMOGRAPHY USING PLENOPTIC IMAGING 有权
    使用PLENOPTIC IMAGING进行眼科TOMOGRAPHY的系统和方法

    公开(公告)号：US20140268041A1

    公开(公告)日：2014-09-18

    申请号：US13829317

    申请日：2013-03-14

    申请人： AMO WAVEFRONT SCIENCES, LLC.

    发明人： Richard J. Copland

    IPC分类号： A61B3/10

    CPC分类号： A61B3/102 ,  A61B3/1015 ,  A61B3/14

    摘要： Improved systems and methods for ocular tomography are provided. These systems and methods can be used to improve the effectiveness of a wide variety of different ophthalmic diagnostic procedures, and various surgical and non-surgical treatments. One embodiment provides a system and method for determining ocular tomography data for the eye using a plenoptic detector. For example, an ocular tomography system can comprise a set of light sources configured to illuminate an eye, a plenoptic detector configured to receive images of the light sources reflected from surfaces of the eye and generate plenoptic image data representing the images, and a processing system coupled to the plenoptic detector. The processing system is configured to analyze the plenoptic image data to determine tomography data for the eye.

    摘要翻译： 提供了用于眼部断层扫描的改进的系统和方法。 这些系统和方法可用于改善各种不同眼科诊断程序以及各种手术和非手术治疗的有效性。 一个实施例提供了一种使用全光检测器确定眼睛的眼部断层摄影数据的系统和方法。 例如，眼部断层摄影系统可以包括被配置为照亮眼睛的一组光源，全光检测器，被配置为接收从眼睛表面反射的光源的图像，并且生成表示图像的全光图像数据，以及处理系统 耦合到全光检测器。 处理系统被配置为分析全光图像数据以确定眼睛的断层摄影数据。

    Model eye producing a speckle pattern having a reduced bright-to-dark ratio
    48.
    发明授权
    Model eye producing a speckle pattern having a reduced bright-to-dark ratio 有权
    模型眼睛产生具有降低的明暗比的斑点图案

    公开(公告)号：US08517538B2

    公开(公告)日：2013-08-27

    申请号：US13011003

    申请日：2011-01-21

    申请人： Richard James Copland

    发明人： Richard James Copland

    IPC分类号： A61B3/00

    CPC分类号： A61B3/0025 ,  A61B3/1015 ,  A61B3/102 ,  A61B2017/00716 ,  A61B2560/0233 ,  G02B27/48

    摘要： A model eye includes an optically transmissive structure having a front curved surface to receive a coherent light beam, and an opposite rear planar surface for directing a portion of the coherent light beam back out the model eye through the front curved surface; and a material structure adhered to the rear planar surface of the optically transmissive structure that has a characteristic to cause a speckle pattern of the portion of the coherent light beam that is directed back out the front curved surface of the optically transmissive structure to have a bright-to-dark ratio of less than 2:1. In some embodiments, the material structure may include a fabric-reinforced polyethylene tape adhered to the rear planar surface of the optically transmissive structure by an adhesive. One example material structure which may be employed is duct tape.

    摘要翻译： 模型眼包括具有前曲面以接收相干光束的光透射结构，以及相对的后平面表面，用于将相干光束的一部分通过前曲面反射回模眼; 以及粘附到光学透射结构的后平面的材料结构，其具有使相干光束的部分的光斑图案从光学透射结构的前曲面引导出来的特征，具有明亮 - 暗比例小于2：1。 在一些实施例中，材料结构可以包括通过粘合剂粘附到光学透射结构的后平面表面上的织物增强聚乙烯带。 可以使用的一个示例性材料结构是导管带。

    SYSTEMS AND METHODS OF PHASE DIVERSITY WAVEFRONT SENSING
    49.
    发明申请
    SYSTEMS AND METHODS OF PHASE DIVERSITY WAVEFRONT SENSING 有权
    相位差波浪感测的系统与方法

    公开(公告)号：US20120293769A1

    公开(公告)日：2012-11-22

    申请号：US13299466

    申请日：2011-11-18

    申请人： Thomas D. Raymond ,  Paul Pulaski ,  Stephen W. Farrer ,  Daniel R. Neal ,  Alan H. Greenaway ,  David M. Faichnie ,  Heather I. Campbell Dalgarno ,  Graham N. Craik

    发明人： Thomas D. Raymond ,  Paul Pulaski ,  Stephen W. Farrer ,  Daniel R. Neal ,  Alan H. Greenaway ,  David M. Faichnie ,  Heather I. Campbell Dalgarno ,  Graham N. Craik

    IPC分类号： A61B3/14 ,  G01M11/02 ,  A61B3/10

    CPC分类号： G01M11/0292 ,  A61B3/1015 ,  G01J9/00

    摘要： A phase diversity wavefront sensor includes an optical system including at least one optical element for receiving a light beam; a diffractive optical element having a diffractive pattern defining a filter function, the diffractive optical element being arranged to produce, in conjunction with the optical system, images from the light beam associated with at least two diffraction orders; and a detector for detecting the images and outputting image data corresponding to the detected images. In one embodiment, the optical system, diffractive optical element, and detector are arranged to provide telecentric, pupil plane images of the light beam. A processor receives the image data from the detector, and executes a Gerchberg-Saxton phase retrieval algorithm to measure the wavefront of the light beam.

    摘要翻译： 相位分集波前传感器包括光学系统，该光学系统包括用于接收光束的至少一个光学元件; 具有限定滤光器功能的衍射图案的衍射光学元件，所述衍射光学元件布置成与所述光学系统结合产生与至少两个衍射级相关联的光束的图像; 以及用于检测图像并输出与检测到的图像相对应的图像数据的检测器。 在一个实施例中，光学系统，衍射光学元件和检测器被布置成提供光束的远心光瞳平面图像。 处理器从检测器接收图像数据，并且执行Gerchberg-Saxton相位检索算法来测量光束的波前。

    TREATMENT PLANNING METHOD AND SYSTEM FOR CONTROLLING LASER REFRACTIVE SURGERY
    50.
    发明申请
    TREATMENT PLANNING METHOD AND SYSTEM FOR CONTROLLING LASER REFRACTIVE SURGERY 审中-公开
    用于控制激光折射手术的治疗计划方法和系统

    公开(公告)号：US20120172854A1

    公开(公告)日：2012-07-05

    申请号：US13341385

    申请日：2011-12-30

    申请人： Thomas D. Raymond ,  Daniel R. Neal

    发明人： Thomas D. Raymond ,  Daniel R. Neal

    IPC分类号： A61B3/107 ,  A61F9/01 ,  A61B3/10

    CPC分类号： A61F9/008 ,  A61F2009/00857 ,  A61F2009/00859 ,  A61F2009/00872 ,  A61F2009/0088

    摘要： Improved devices, systems, and methods for diagnosing, planning treatments of, and/or treating the refractive structures of an eye of a patient incorporate results of prior refractive corrections into a planned refractive treatment of a particular patient by driving an effective treatment vector function based on data from the prior eye treatments. The exemplary effective treatment vector employs an influence matrix which may allow improved refractive corrections to be generated so as to increase the overall accuracy of laser eye surgery (including LASIK, PRK, and the like), customized intraocular lenses (IOLs), refractive femtosecond treatments, and the like.

    摘要翻译： 用于诊断，规划治疗和/或治疗患者的眼睛的折射结构的改进的装置，系统和方法将先前的屈光矫正的结果并入特定患者的计划折射治疗中，通过基于有效的治疗向量函数 来自先前的眼睛治疗的数据。 示例性的有效治疗载体使用影响矩阵，其可以允许产生改善的屈光矫正以增加激光眼睛手术（包括LASIK，PRK等），定制的眼内透镜（IOL），折射飞秒处理 ，等等。