Calcium-containing structures and methods of making and using the same
    43.
    发明授权
    Calcium-containing structures and methods of making and using the same 有权
    含钙结构及其制造和使用方法

    公开(公告)号:US08389017B1

    公开(公告)日:2013-03-05

    申请号:US10030578

    申请日:2000-07-07

    IPC分类号: A61K33/00 A61K33/14 A01N59/08

    摘要: The present invention generally relates to calcium-containing structures and methods of making and using the structures. In one aspect, hollow calcium containing microstructures are used in conjunction with bone tissues/by-products to augment bone defects and extend the supply of bone tissues/by-products for bone augmentation. Bonding agents, such as calcium cements, are also used in the preparation of the hollow calcium microstructures combined with bone tissues/by-products or for use in preparing the hollow microstructures. The calcium-containing microstructures of the present invention are also useful as delivery vehicles of nitric oxide and/or nitric oxide containing or producing compounds for a variety of in vitro and in vivo uses. Calcium containing contoured substrates upon which cells/tissues can be grown in vitro for replacement and repair of tissues in vivo that conform in size and shape to the tissue surface to be replaced are also provided.

    摘要翻译: 本发明一般涉及含钙结构及其制造和使用方法。 在一个方面,含空心钙微结构与骨组织/副产物结合使用,以增加骨缺损并延长骨组织/副产物的供应以增加骨骼。 粘结剂,例如钙粘结剂,也用于制备与骨组织/副产物组合的中空钙微结构或用于制备中空微结构。 本发明的含钙微结构也可用作含有或用于各种体外和体内用途的化合物的一氧化氮和/或一氧化氮的输送载体。 还提供含钙成分的基质,细胞/组织可以在其上体外生长,用于体内组织的组织替换和修复,其尺寸和形状与待替换的组织表面一致。

    Method and apparatus for producing a stablized antimicrobial non-toxic electrolyzed saline solution exhibiting potential as a therapeutic
    44.
    发明授权
    Method and apparatus for producing a stablized antimicrobial non-toxic electrolyzed saline solution exhibiting potential as a therapeutic 有权
    用于生产稳定的抗微生物无毒电解盐水溶液的方法和装置,其表现出作为治疗剂的潜力

    公开(公告)号:US08367120B1

    公开(公告)日:2013-02-05

    申请号:US12383212

    申请日:2009-03-20

    摘要: An improved method and apparatus for producing a stable, non-toxic, antimicrobial electrolyzed saline solution with a broad range of anti-infective and therapeutic applications. The resulting electrolyzed saline solution exhibits a marked lack of toxicity upon intravenous, aspired, oral or topical application in mammals for therapeutic applications providing a broad platform, including topical disinfection, antimicrobial application, wound treatment, oxidative stress reduction and enhancement of immune function to better detect malfunctioning cells.

    摘要翻译: 一种用于生产具有广泛抗感染和治疗应用的稳定,无毒,抗菌的电解盐水溶液的改进方法和装置。 所得到的电解盐水溶液在哺乳动物中的静脉内,吸入,口服或局部施用时显示出明显的毒性,用于提供广泛平台的治疗应用,包括局部消毒,抗微生物施用,伤口治疗,氧化应激降低和增强免疫功能以达到更佳 检测故障单元。

    Nasal composition
    46.
    发明授权
    Nasal composition 失效
    鼻组成

    公开(公告)号:US08337906B2

    公开(公告)日:2012-12-25

    申请号:US12885715

    申请日:2010-09-20

    摘要: A nasal spray solution for use as a nasal spray and methods of using the solution are disclosed. The nasal spray solution moisturizes nasal passages and alleviates nasal dryness. The solution includes a hypotonic saline solution, wherein the saline solution is hypotonic with respect to cells of the nasal mucosa of the nasal passages, a buffering agent, a lubricating agent, and an anti-microbial agent.

    摘要翻译: 公开了用作鼻喷雾剂的鼻喷雾溶液和使用该溶液的方法。 鼻喷雾溶液滋润鼻道,减轻鼻腔干燥。 溶液包括低渗盐水溶液,其中盐溶液相对于鼻通道的鼻粘膜的细胞,缓冲剂,润滑剂和抗微生物剂是低渗的。