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    Personal care composition containing leghemoglobin
    41.
    发明申请
    Personal care composition containing leghemoglobin 有权
    含有血红蛋白的个人护理组合物

    公开(公告)号：US20030198700A1

    公开(公告)日：2003-10-23

    申请号：US10366231

    申请日：2003-02-13

    发明人： James V. Gruber

    IPC分类号： A61K038/16 ,  A61K031/715 ,  A61K009/70 ,  A61K035/78

    CPC分类号： A61K8/068 ,  A61K8/645 ,  A61K8/97 ,  A61Q17/00 ,  A61Q19/00 ,  A61Q19/04

    摘要： A personal care composition comprising leghemoglobin and at least one preservative selected from the group consisting of alcohols, glycols, parabens, hydantoins, quaternary nitrogen-containing compounds, isothiazolinones, aldehyde-releasing agents, and halogenated compounds. Preferably, the leghemoglobin is a nitrogen fixation root nodule extract providing a leghemoglobin concentration in the composition of between 0.0001% and about 10% based upon the total weight of the composition. Also disclosed is a method for preparing the personal care composition.

    摘要翻译： 一种个人护理组合物，其包含腿血红蛋白和选自醇，二醇，对羟基苯甲酸酯，乙内酰脲，含季氮化合物，异噻唑啉酮，醛释放剂和卤代化合物的至少一种防腐剂。 优选地，血红蛋白是固氮根结节提取物，其组合物中基于组合物的总重量提供0.0001％至约10％之间的血红蛋白浓度。 还公开了一种制备个人护理组合物的方法。

    Method for treatment of inflammation and pain in mammals
    45.
    发明申请
    Method for treatment of inflammation and pain in mammals 有权
    哺乳动物炎症和疼痛的治疗方法

    公开(公告)号：US20030185907A1

    公开(公告)日：2003-10-02

    申请号：US10378572

    申请日：2003-03-03

    发明人： Kim Carleton Krumhar

    IPC分类号： A61K035/78 ,  A61K031/715

    CPC分类号： A61K36/324 ,  A61K36/67 ,  A61K36/752 ,  A61K36/9066 ,  A61K2300/00

    摘要： A composition for treating inflammation and pain in mammals, particularly humans. Effective amounts of a boswellic acid, a curcuminoid, a gingerol, a capsaicinoid, a bioflavonoid, and a vitamin C source, in various combinations, all preferably from a botanical source, are blended to form a dose for oral administration. Administration of the dose provides relief from pain and inflammation of connective tissue. The dose may be administered as a tablet, a liquid, or a powder.

    摘要翻译： 用于治疗哺乳动物，特别是人类的炎症和疼痛的组合物。 将各种组合的所有优选来自植物来源的保乳酸，姜黄素，姜醇，辣椒素，生物类黄酮和维生素C源的有效量混合以形成口服给药剂量。 剂量的施用提供缓解结缔组织的疼痛和炎症。 该剂量可以片剂，液体或粉末施用。

    Hemostatic bone wax composition
    47.
    发明申请
    Hemostatic bone wax composition 审中-公开
    止血骨蜡组成

    公开(公告)号：US20030153528A1

    公开(公告)日：2003-08-14

    申请号：US10267940

    申请日：2002-10-09

    发明人： Melvin E. Levinson

    IPC分类号： A61K031/715

    CPC分类号： A61K31/715 ,  A61B17/0057 ,  A61F13/00 ,  A61F2013/00412 ,  A61F2013/00472 ,  A61L2400/04

    摘要： A hemostatic composition for effecting hemostasis at a hemorrhaging site comprises a hemostatically effective amount of cationic substance and a wax base, wherein the cationic substance is substantially uniformly dispersed in the bone wax base. The method of preparing the hemostatic composition includes admixing an aqueous solution of a cationic substance and a bone wax, and freeze-drying the mixture to remove substantially all of the water to yield a viscous water soluble composition of fine particles of cationic which is substantially uniformly dispersed throughout the bone wax base. The method for effecting hemostasis comprises making the hemostatic composition and applying a hemostatically effective amount of the hemostatic composition to the hemorrhaging site.

    摘要翻译： 用于在出血部位进行止血的止血组合物包含止血有效量的阳离子物质和蜡碱，其中阳离子物质基本均匀地分散在骨蜡基质中。 制备止血组合物的方法包括混合阳离子物质和骨蜡的水溶液，并将混合物冷冻干燥以除去基本上所有的水，得到基本均匀的阳离子细颗粒的粘性水溶性组合物 分散在骨蜡基底部。 进行止血的方法包括使止血组合物和止血组合物施用至出血部位。

    Hemostatic composition
    48.
    发明申请
    Hemostatic composition 审中-公开
    止血组成

    公开(公告)号：US20030148994A1

    公开(公告)日：2003-08-07

    申请号：US10267902

    申请日：2002-10-09

    发明人： Melvin E. Levinson

    IPC分类号： A61K031/715

    CPC分类号： A61K31/715 ,  A61B17/0057 ,  A61F13/00 ,  A61F2013/00412 ,  A61F2013/00472 ,  A61L2400/04

    摘要： A hemostatic composition for effecting hemostasis at a hemorrhaging site comprises a hemostatically effective amount of cationic substance and a base, wherein the base is in a form of an ointment, a cream, a gel, a foam or a paste, and wherein the cationic substance is substantially uniformly dispersed in the base. The method of preparing the hemostatic composition includes admixing an aqueous solution of a cationic substance and the base, and freeze-drying the mixture to remove substantially all of the water to yield a viscous water soluble composition of fine particles of cationic which is substantially uniformly dispersed throughout the base, and the method of its use to provide hemostasis to a hemorrhaging site of a mammal.

    摘要翻译： 用于在出血部位进行止血的止血组合物包括止血有效量的阳离子物质和碱，其中所述碱为软膏，霜剂，凝胶，泡沫或糊剂的形式，并且其中所述阳离子物质 基本均匀地分散在基材中。 制备止血组合物的方法包括将阳离子物质的水溶液与碱混合，并将混合物冷冻干燥以除去基本上所有的水，得到基本均匀分散的阳离子细颗粒的粘性水溶性组合物 在整个基地，以及其用于向哺乳动物的出血部位提供止血的方法。

    Method of achieving persistent transgene expression
    49.
    发明申请
    Method of achieving persistent transgene expression 审中-公开
    实现持续转基因表达的方法

    公开(公告)号：US20030148975A1

    公开(公告)日：2003-08-07

    申请号：US10169323

    申请日：2002-10-23

    发明人： David Ennist ,  Patrick Lu ,  Mervat Mina

    IPC分类号： A61K048/00 ,  A61K031/715 ,  A61K031/573

    CPC分类号： C12N15/87 ,  A61K48/0075 ,  A61K48/0083

    摘要： Non-inflammatory vector compositions are provided that are suitable for repeated transgene delivery and that result in persistent transgene expression. The compositions are non-inflammatory, the present compositions are suitable for readministration and do not induce expression-limiting immune or inflammatory responses. Thus, these compositions are useful in methods of repeated administration to achieve persistent transgene expression, and are especially suited to treating genetic, acquired and inflammation-associated conditions.

    摘要翻译： 提供非炎症载体组合物，其适用于重复的转基因递送，并导致持续的转基因表达。 组合物是非炎性的，本发明的组合物适用于再次给药并且不诱导表达限制性免疫或炎症反应。 因此，这些组合物可用于重复施用以实现持续转基因表达的方法，并且特别适合于治疗遗传，获得性和炎症相关病症。